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Items: 1 to 50 of 117

1.

Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome.

Manners MT, Yohn NL, Lahens NF, Grant GR, Bartolomei MS, Blendy JA.

Genes Brain Behav. 2018 Jun 13:e12493. doi: 10.1111/gbb.12493. [Epub ahead of print]

PMID:
29896789
2.

Activation of AMPK by metformin improves withdrawal signs precipitated by nicotine withdrawal.

Brynildsen JK, Lee BG, Perron IJ, Jin S, Kim SF, Blendy JA.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4282-4287. doi: 10.1073/pnas.1707047115. Epub 2018 Apr 2.

3.

Genetic variation in the behavioral effects of buprenorphine in female mice derived from a murine model of the OPRM1 A118G polymorphism.

Browne CA, Erickson RL, Blendy JA, Lucki I.

Neuropharmacology. 2017 May 1;117:401-407. doi: 10.1016/j.neuropharm.2017.02.005. Epub 2017 Feb 7.

4.

Adolescent Chronic Unpredictable Stress Exposure Is a Sensitive Window for Long-Term Changes in Adult Behavior in Mice.

Yohn NL, Blendy JA.

Neuropsychopharmacology. 2017 Jul;42(8):1670-1678. doi: 10.1038/npp.2017.11. Epub 2017 Jan 17.

5.

Long-lasting effects of adolescent oxycodone exposure on reward-related behavior and gene expression in mice.

Sanchez V, Carpenter MD, Yohn NL, Blendy JA.

Psychopharmacology (Berl). 2016 Dec;233(23-24):3991-4002. Epub 2016 Sep 13.

6.

Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions.

Wood KH, Johnson BS, Welsh SA, Lee JY, Cui Y, Krizman E, Brodkin ES, Blendy JA, Robinson MB, Bartolomei MS, Zhou Z.

Epigenomics. 2016 Apr;8(4):455-73. doi: 10.2217/epi-2015-0004. Epub 2016 Apr 12.

7.

Translational Research on Nicotine Dependence.

Falcone M, Lee B, Lerman C, Blendy JA.

Curr Top Behav Neurosci. 2016;28:121-50. doi: 10.1007/7854_2015_5005. Review.

PMID:
26873019
8.

Anxiolytic- and antidepressant-like effects of the methadone metabolite 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP).

Forcelli PA, Turner JR, Lee BG, Olson TT, Xie T, Xiao Y, Blendy JA, Kellar KJ.

Neuropharmacology. 2016 Feb;101:46-56. doi: 10.1016/j.neuropharm.2015.09.012. Epub 2015 Sep 11.

9.

Multigenerational and transgenerational inheritance of drug exposure: The effects of alcohol, opiates, cocaine, marijuana, and nicotine.

Yohn NL, Bartolomei MS, Blendy JA.

Prog Biophys Mol Biol. 2015 Jul;118(1-2):21-33. doi: 10.1016/j.pbiomolbio.2015.03.002. Epub 2015 Apr 1. Review.

10.

Effects of the BDNF Val66Met Polymorphism on Anxiety-Like Behavior Following Nicotine Withdrawal in Mice.

Lee BG, Anastasia A, Hempstead BL, Lee FS, Blendy JA.

Nicotine Tob Res. 2015 Dec;17(12):1428-35. doi: 10.1093/ntr/ntv047. Epub 2015 Mar 5.

11.

Mouse model of OPRM1 (A118G) polymorphism increases sociability and dominance and confers resilience to social defeat.

Briand LA, Hilario M, Dow HC, Brodkin ES, Blendy JA, Berton O.

J Neurosci. 2015 Feb 25;35(8):3582-90. doi: 10.1523/JNEUROSCI.4685-14.2015.

12.

Serine 133 phosphorylation is not required for hippocampal CREB-mediated transcription and behavior.

Briand LA, Lee BG, Lelay J, Kaestner KH, Blendy JA.

Learn Mem. 2015 Jan 15;22(2):109-15. doi: 10.1101/lm.037044.114. Print 2015 Feb.

13.

Mouse model of the OPRM1 (A118G) polymorphism: differential heroin self-administration behavior compared with wild-type mice.

Zhang Y, Picetti R, Butelman ER, Ho A, Blendy JA, Kreek MJ.

Neuropsychopharmacology. 2015 Mar 13;40(5):1091-100. doi: 10.1038/npp.2014.286.

14.

Cellular origins of auditory event-related potential deficits in Rett syndrome.

Goffin D, Brodkin ES, Blendy JA, Siegel SJ, Zhou Z.

Nat Neurosci. 2014 Jun;17(6):804-6. doi: 10.1038/nn.3710. Epub 2014 Apr 28.

15.

Activation of α4β2*/α6β2* nicotinic receptors alleviates anxiety during nicotine withdrawal without upregulating nicotinic receptors.

Yohn NL, Turner JR, Blendy JA.

J Pharmacol Exp Ther. 2014 May;349(2):348-54. doi: 10.1124/jpet.113.211706. Epub 2014 Mar 13.

16.

Dissociation of tolerance and nicotine withdrawal-associated deficits in contextual fear.

Gould TJ, Wilkinson DS, Yildirim E, Blendy JA, Adoff MD.

Brain Res. 2014 Apr 22;1559:1-10. doi: 10.1016/j.brainres.2014.02.038. Epub 2014 Mar 2.

17.

Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits.

Ting JH, Marks DR, Schleidt SS, Wu JN, Zyskind JW, Lindl KA, Blendy JA, Pierce RC, Jordan-Sciutto KL.

J Neurochem. 2014 Jun;129(5):850-63. doi: 10.1111/jnc.12655. Epub 2014 Feb 12.

18.

Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain.

Hussmann GP, DeDominicis KE, Turner JR, Yasuda RP, Klehm J, Forcelli PA, Xiao Y, Richardson JR, Sahibzada N, Wolfe BB, Lindstrom J, Blendy JA, Kellar KJ.

J Neurochem. 2014 May;129(4):721-31. doi: 10.1111/jnc.12653. Epub 2014 Feb 7.

19.

Evidence from mouse and man for a role of neuregulin 3 in nicotine dependence.

Turner JR, Ray R, Lee B, Everett L, Xiang J, Jepson C, Kaestner KH, Lerman C, Blendy JA.

Mol Psychiatry. 2014 Jul;19(7):801-10. doi: 10.1038/mp.2013.104. Epub 2013 Sep 3.

20.

Increased hippocampal neurogenesis and accelerated response to antidepressants in mice with specific deletion of CREB in the hippocampus: role of cAMP response-element modulator τ.

Gundersen BB, Briand LA, Onksen JL, Lelay J, Kaestner KH, Blendy JA.

J Neurosci. 2013 Aug 21;33(34):13673-85. doi: 10.1523/JNEUROSCI.1669-13.2013.

21.

Antidepressant-like properties of novel HDAC6-selective inhibitors with improved brain bioavailability.

Jochems J, Boulden J, Lee BG, Blendy JA, Jarpe M, Mazitschek R, Van Duzer JH, Jones S, Berton O.

Neuropsychopharmacology. 2014 Jan;39(2):389-400. doi: 10.1038/npp.2013.207. Epub 2013 Aug 19.

22.

Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal.

Turner JR, Wilkinson DS, Poole RL, Gould TJ, Carlson GC, Blendy JA.

Neuropsychopharmacology. 2013 Sep;38(10):2035-47. doi: 10.1038/npp.2013.105. Epub 2013 Apr 29.

23.

Not all stress is equal: CREB is not necessary for restraint stress reinstatement of cocaine-conditioned reward.

Briand LA, Blendy JA.

Behav Brain Res. 2013 Jun 1;246:63-8. doi: 10.1016/j.bbr.2013.02.026. Epub 2013 Mar 1.

24.

Translational research in nicotine dependence.

Turner JR, Gold A, Schnoll R, Blendy JA.

Cold Spring Harb Perspect Med. 2013 Mar 1;3(3):a012153. doi: 10.1101/cshperspect.a012153. Review.

25.

Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice.

Wang IT, Allen M, Goffin D, Zhu X, Fairless AH, Brodkin ES, Siegel SJ, Marsh ED, Blendy JA, Zhou Z.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21516-21. doi: 10.1073/pnas.1216988110. Epub 2012 Dec 10.

26.

Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice.

Balu DT, Turner JR, Brookshire BR, Hill-Smith TE, Blendy JA, Lucki I.

Neuropharmacology. 2013 Apr;67:503-10. doi: 10.1016/j.neuropharm.2012.11.027. Epub 2012 Dec 6.

27.

Cocaine-related behaviors in mice with deficient gliotransmission.

Turner JR, Ecke LE, Briand LA, Haydon PG, Blendy JA.

Psychopharmacology (Berl). 2013 Mar;226(1):167-76. doi: 10.1007/s00213-012-2897-4. Epub 2012 Oct 27.

28.

Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.

Hussmann GP, Turner JR, Lomazzo E, Venkatesh R, Cousins V, Xiao Y, Yasuda RP, Wolfe BB, Perry DC, Rezvani AH, Levin ED, Blendy JA, Kellar KJ.

J Pharmacol Exp Ther. 2012 Nov;343(2):441-50. doi: 10.1124/jpet.112.198085. Epub 2012 Aug 16.

29.

Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G.

Wang YJ, Huang P, Blendy JA, Liu-Chen LY.

Addict Biol. 2014 May;19(3):354-61. doi: 10.1111/j.1369-1600.2012.00484.x. Epub 2012 Aug 2.

30.

Genetic background influences the effects of withdrawal from chronic nicotine on learning and high-affinity nicotinic acetylcholine receptor binding in the dorsal and ventral hippocampus.

Wilkinson DS, Turner JR, Blendy JA, Gould TJ.

Psychopharmacology (Berl). 2013 Jan;225(1):201-8. doi: 10.1007/s00213-012-2808-8. Epub 2012 Jul 27.

31.

Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice.

Hilario MR, Turner JR, Blendy JA.

Neuropsychopharmacology. 2012 Nov;37(12):2661-70. doi: 10.1038/npp.2012.130. Epub 2012 Jul 25.

32.

Galantamine, an acetylcholinesterase inhibitor and positive allosteric modulator of nicotinic acetylcholine receptors, attenuates nicotine taking and seeking in rats.

Hopkins TJ, Rupprecht LE, Hayes MR, Blendy JA, Schmidt HD.

Neuropsychopharmacology. 2012 Sep;37(10):2310-21. doi: 10.1038/npp.2012.83. Epub 2012 Jun 6.

33.

Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning.

Portugal GS, Wilkinson DS, Turner JR, Blendy JA, Gould TJ.

Neurobiol Learn Mem. 2012 May;97(4):482-94. doi: 10.1016/j.nlm.2012.04.003. Epub 2012 Apr 11.

34.

Running-induced anxiety is dependent on increases in hippocampal neurogenesis.

Onksen JL, Briand LA, Galante RJ, Pack AI, Blendy JA.

Genes Brain Behav. 2012 Jul;11(5):529-38. doi: 10.1111/j.1601-183X.2012.00788.x. Epub 2012 May 3.

35.

Enhanced extinction of cocaine seeking in brain-derived neurotrophic factor Val66Met knock-in mice.

Briand LA, Lee FS, Blendy JA, Pierce RC.

Eur J Neurosci. 2012 Mar;35(6):932-9. doi: 10.1111/j.1460-9568.2012.08021.x. Epub 2012 Mar 7.

36.

μ-Opioid receptor availability in the amygdala is associated with smoking for negative affect relief.

Falcone M, Gold AB, Wileyto EP, Ray R, Ruparel K, Newberg A, Dubroff J, Logan J, Zubieta JK, Blendy JA, Lerman C.

Psychopharmacology (Berl). 2012 Aug;222(4):701-8. doi: 10.1007/s00213-012-2673-5. Epub 2012 Mar 3.

37.

Behavioral and activity assessment of laboratory mice (Mus musculus) after tail biopsy under isoflurane anesthesia.

Hankenson FC, Braden-Weiss GC, Blendy JA.

J Am Assoc Lab Anim Sci. 2011 Sep;50(5):686-94.

38.

Reduced expression of the μ opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G.

Wang YJ, Huang P, Ung A, Blendy JA, Liu-Chen LY.

Neuroscience. 2012 Mar 15;205:178-84. doi: 10.1016/j.neuroscience.2011.12.033. Epub 2012 Jan 3.

39.

Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses.

Goffin D, Allen M, Zhang L, Amorim M, Wang IT, Reyes AR, Mercado-Berton A, Ong C, Cohen S, Hu L, Blendy JA, Carlson GC, Siegel SJ, Greenberg ME, Zhou Z.

Nat Neurosci. 2011 Nov 27;15(2):274-83. doi: 10.1038/nn.2997.

40.

Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 (Pdss2) mutant mice.

Ziegler CG, Peng M, Falk MJ, Polyak E, Tsika E, Ischiropoulos H, Bakalar D, Blendy JA, Gasser DL.

Mitochondrion. 2012 Mar;12(2):248-57. doi: 10.1016/j.mito.2011.09.011. Epub 2011 Oct 1.

41.

Depressive phenotypes evoked by experimental diabetes are reversed by insulin.

Ho N, Balu DT, Hilario MR, Blendy JA, Lucki I.

Physiol Behav. 2012 Feb 1;105(3):702-8. doi: 10.1016/j.physbeh.2011.09.003. Epub 2011 Sep 10.

42.

The role of the Asn40Asp polymorphism of the mu opioid receptor gene (OPRM1) on alcoholism etiology and treatment: a critical review.

Ray LA, Barr CS, Blendy JA, Oslin D, Goldman D, Anton RF.

Alcohol Clin Exp Res. 2012 Mar;36(3):385-94. doi: 10.1111/j.1530-0277.2011.01633.x. Epub 2011 Sep 6. Review.

43.

Decreased CREB levels suppress epilepsy.

Zhu X, Han X, Blendy JA, Porter BE.

Neurobiol Dis. 2012 Jan;45(1):253-63. doi: 10.1016/j.nbd.2011.08.009. Epub 2011 Aug 10.

44.

A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability.

Huang P, Chen C, Mague SD, Blendy JA, Liu-Chen LY.

Biochem J. 2012 Jan 1;441(1):379-86. doi: 10.1042/BJ20111050.

45.

Human Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers.

Ray R, Ruparel K, Newberg A, Wileyto EP, Loughead JW, Divgi C, Blendy JA, Logan J, Zubieta JK, Lerman C.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9268-73. doi: 10.1073/pnas.1018699108. Epub 2011 May 16.

46.

Selective deletion of a cell cycle checkpoint kinase (ATR) reduces neurogenesis and alters responses in rodent models of behavioral affect.

Onksen JL, Brown EJ, Blendy JA.

Neuropsychopharmacology. 2011 Apr;36(5):960-9. doi: 10.1038/npp.2010.234. Epub 2011 Jan 19.

47.

CREB-mediated alterations in the amygdala transcriptome: coordinated regulation of immune response genes following cocaine.

Ecke LE, Cleck JN, White P, Schug J, Mifflin L, Blendy JA.

Int J Neuropsychopharmacol. 2011 Sep;14(8):1111-26. doi: 10.1017/S1461145710001392. Epub 2010 Dec 8.

48.

Ventral tegmental afferents in stress-induced reinstatement: the role of cAMP response element-binding protein.

Briand LA, Vassoler FM, Pierce RC, Valentino RJ, Blendy JA.

J Neurosci. 2010 Dec 1;30(48):16149-59. doi: 10.1523/JNEUROSCI.2827-10.2010.

49.

Modeling neuropsychiatric disease-relevant human SNPs in mice.

Blendy JA.

Neuropsychopharmacology. 2011 Jan;36(1):364-5. doi: 10.1038/npp.2010.143. No abstract available.

50.

Parallel anxiolytic-like effects and upregulation of neuronal nicotinic acetylcholine receptors following chronic nicotine and varenicline.

Turner JR, Castellano LM, Blendy JA.

Nicotine Tob Res. 2011 Jan;13(1):41-6. doi: 10.1093/ntr/ntq206. Epub 2010 Nov 22.

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