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Items: 1 to 50 of 222

1.

An In Vitro Model for Identifying Cardiac Side Effects of Anesthetics.

Chang ACY, Chang ACH, Nicin L, Weber GJ, Holbrook C, Davies MF, Blau HM, Bertaccini EJ.

Anesth Analg. 2018 Sep 5. doi: 10.1213/ANE.0000000000003757. [Epub ahead of print]

PMID:
30198930
2.

Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy.

Ho PP, Lahey LJ, Mourkioti F, Kraft PE, Filareto A, Brandt M, Magnusson KEG, Finn EE, Chamberlain JS, Robinson WH, Blau HM, Steinman L.

Proc Natl Acad Sci U S A. 2018 Sep 4. pii: 201808648. doi: 10.1073/pnas.1808648115. [Epub ahead of print]

PMID:
30181272
3.

Telomere shortening is a hallmark of genetic cardiomyopathies.

Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, Ashley E, Wu JC, Blau HM.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9276-9281. doi: 10.1073/pnas.1714538115. Epub 2018 Aug 27.

4.

A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells.

Tichy ED, Sidibe DK, Greer CD, Oyster NM, Rompolas P, Rosenthal NA, Blau HM, Mourkioti F.

Skelet Muscle. 2018 Aug 24;8(1):27. doi: 10.1186/s13395-018-0169-7.

5.

NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction.

Mai T, Markov GJ, Brady JJ, Palla A, Zeng H, Sebastiano V, Blau HM.

Nat Cell Biol. 2018 Aug;20(8):900-908. doi: 10.1038/s41556-018-0136-x. Epub 2018 Jul 16.

PMID:
30013107
6.

Bioengineering strategies to accelerate stem cell therapeutics.

Madl CM, Heilshorn SC, Blau HM.

Nature. 2018 May;557(7705):335-342. doi: 10.1038/s41586-018-0089-z. Epub 2018 May 16. Review.

PMID:
29769665
7.

Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M.

Sampath SC, Sampath SC, Ho ATV, Corbel SY, Millstone JD, Lamb J, Walker J, Kinzel B, Schmedt C, Blau HM.

Nat Commun. 2018 Apr 18;9(1):1531. doi: 10.1038/s41467-018-03876-8.

8.

Publisher Correction: High-resolution myogenic lineage mapping by single-cell mass cytometry.

Porpiglia E, Samusik N, Ho ATV, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM.

Nat Cell Biol. 2018 Aug;20(8):990. doi: 10.1038/s41556-018-0043-1.

PMID:
29507406
9.

Short telomeres - A hallmark of heritable cardiomyopathies.

Chang ACY, Blau HM.

Differentiation. 2018 Mar - Apr;100:31-36. doi: 10.1016/j.diff.2018.02.001. Epub 2018 Feb 9. Review.

PMID:
29482077
10.

Humanizing the mdx mouse model of DMD: the long and the short of it.

Yucel N, Chang AC, Day JW, Rosenthal N, Blau HM.

NPJ Regen Med. 2018 Feb 16;3:4. doi: 10.1038/s41536-018-0045-4. eCollection 2018. Review.

11.

Muscling toward therapy with ERBB3 and NGFR.

Ho ATV, Blau HM.

Nat Cell Biol. 2018 Jan;20(1):6-7. doi: 10.1038/s41556-017-0015-x. No abstract available.

PMID:
29269948
12.

An objective comparison of cell-tracking algorithms.

Ulman V, Maška M, Magnusson KEG, Ronneberger O, Haubold C, Harder N, Matula P, Matula P, Svoboda D, Radojevic M, Smal I, Rohr K, Jaldén J, Blau HM, Dzyubachyk O, Lelieveldt B, Xiao P, Li Y, Cho SY, Dufour AC, Olivo-Marin JC, Reyes-Aldasoro CC, Solis-Lemus JA, Bensch R, Brox T, Stegmaier J, Mikut R, Wolf S, Hamprecht FA, Esteves T, Quelhas P, Demirel Ö, Malmström L, Jug F, Tomancak P, Meijering E, Muñoz-Barrutia A, Kozubek M, Ortiz-de-Solorzano C.

Nat Methods. 2017 Dec;14(12):1141-1152. doi: 10.1038/nmeth.4473. Epub 2017 Oct 30.

13.

Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation.

Sleep E, Cosgrove BD, McClendon MT, Preslar AT, Chen CH, Sangji MH, Pérez CMR, Haynes RD, Meade TJ, Blau HM, Stupp SI.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7919-E7928. doi: 10.1073/pnas.1708142114. Epub 2017 Sep 5.

14.

Corrigendum: Dermatologist-level classification of skin cancer with deep neural networks.

Esteva A, Kuprel B, Novoa RA, Ko J, Swetter SM, Blau HM, Thrun S.

Nature. 2017 Jun 28;546(7660):686. doi: 10.1038/nature22985.

PMID:
28658222
15.

Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength.

Ho ATV, Palla AR, Blake MR, Yucel ND, Wang YX, Magnusson KEG, Holbrook CA, Kraft PE, Delp SL, Blau HM.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6675-6684. doi: 10.1073/pnas.1705420114. Epub 2017 Jun 12.

16.

High-resolution myogenic lineage mapping by single-cell mass cytometry.

Porpiglia E, Samusik N, Ho ATV, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM.

Nat Cell Biol. 2017 May;19(5):558-567. doi: 10.1038/ncb3507. Epub 2017 Apr 17. Erratum in: Nat Cell Biol. 2018 Mar 5;:.

17.

Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency.

Theodoris CV, Mourkioti F, Huang Y, Ranade SS, Liu L, Blau HM, Srivastava D.

J Clin Invest. 2017 May 1;127(5):1683-1688. doi: 10.1172/JCI90338. Epub 2017 Mar 27.

18.

Discovery of novel determinants of endothelial lineage using chimeric heterokaryons.

Wong WT, Matrone G, Tian X, Tomoiaga SA, Au KF, Meng S, Yamazoe S, Sieveking D, Chen K, Burns DM, Chen JK, Blau HM, Cooke JP.

Elife. 2017 Mar 21;6. pii: e23588. doi: 10.7554/eLife.23588.

19.

Dermatologist-level classification of skin cancer with deep neural networks.

Esteva A, Kuprel B, Novoa RA, Ko J, Swetter SM, Blau HM, Thrun S.

Nature. 2017 Feb 2;542(7639):115-118. doi: 10.1038/nature21056. Epub 2017 Jan 25. Erratum in: Nature. 2017 Jun 28;546(7660):686.

PMID:
28117445
20.

Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy.

Chang AC, Ong SG, LaGory EL, Kraft PE, Giaccia AJ, Wu JC, Blau HM.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13120-13125. Epub 2016 Oct 31.

21.

Noninvasive Tracking of Quiescent and Activated Muscle Stem Cell (MuSC) Engraftment Dynamics In Vivo.

Ho AT, Blau HM.

Methods Mol Biol. 2016;1460:181-9. doi: 10.1007/978-1-4939-3810-0_13.

PMID:
27492173
22.

Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.

Burridge PW, Li YF, Matsa E, Wu H, Ong SG, Sharma A, Holmström A, Chang AC, Coronado MJ, Ebert AD, Knowles JW, Telli ML, Witteles RM, Blau HM, Bernstein D, Altman RB, Wu JC.

Nat Med. 2016 May;22(5):547-56. doi: 10.1038/nm.4087. Epub 2016 Apr 18.

23.

The central role of muscle stem cells in regenerative failure with aging.

Blau HM, Cosgrove BD, Ho AT.

Nat Med. 2015 Aug;21(8):854-62. doi: 10.1038/nm.3918. Review.

24.

Stem Cells and Aging: What's Next?

Artandi SE, Blau HM, de Haan G, Geiger H, Goodell MA, Jones L, Levine RL, Muñoz-Cánoves P, Rodewald HR, Wagers A, Wang ZQ, Yamashita Y.

Cell Stem Cell. 2015 Jun 4;16(6):578-81. No abstract available.

25.

Turning terminally differentiated skeletal muscle cells into regenerative progenitors.

Wang H, Lööf S, Borg P, Nader GA, Blau HM, Simon A.

Nat Commun. 2015 Aug 5;6:7916. doi: 10.1038/ncomms8916.

26.

Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.

Ramunas J, Yakubov E, Brady JJ, Corbel SY, Holbrook C, Brandt M, Stein J, Santiago JG, Cooke JP, Blau HM.

FASEB J. 2015 May;29(5):1930-9. doi: 10.1096/fj.14-259531. Epub 2015 Jan 22.

27.

Global linking of cell tracks using the Viterbi algorithm.

Magnusson KE, Jalden J, Gilbert PM, Blau HM.

IEEE Trans Med Imaging. 2015 Apr;34(4):911-29. doi: 10.1109/TMI.2014.2370951. Epub 2014 Nov 14.

28.

Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets.

Tamaki S, Nye C, Slorach E, Scharp D, Blau HM, Whiteley PE, Pomerantz JH.

BMC Biotechnol. 2014 Oct 11;14:86. doi: 10.1186/1472-6750-14-86.

29.

Perspective for special Gurdon issue for differentiation: can cell fusion inform nuclear reprogramming?

Burns D, Blau HM.

Differentiation. 2014 Jul;88(1):27-28. doi: 10.1016/j.diff.2014.07.001. Epub 2014 Aug 21.

30.

Sir John Gurdon: father of nuclear reprogramming.

Blau HM.

Differentiation. 2014 Jul;88(1):10-12. doi: 10.1016/j.diff.2014.05.002. Epub 2014 Jun 18.

31.

Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein.

Chu J, Haynes RD, Corbel SY, Li P, González-González E, Burg JS, Ataie NJ, Lam AJ, Cranfill PJ, Baird MA, Davidson MW, Ng HL, Garcia KC, Contag CH, Shen K, Blau HM, Lin MZ.

Nat Methods. 2014 May;11(5):572-8. doi: 10.1038/nmeth.2888. Epub 2014 Mar 16.

32.

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles.

Cosgrove BD, Gilbert PM, Porpiglia E, Mourkioti F, Lee SP, Corbel SY, Llewellyn ME, Delp SL, Blau HM.

Nat Med. 2014 Mar;20(3):255-64. doi: 10.1038/nm.3464. Epub 2014 Feb 16.

33.

A benchmark for comparison of cell tracking algorithms.

Maška M, Ulman V, Svoboda D, Matula P, Matula P, Ederra C, Urbiola A, España T, Venkatesan S, Balak DM, Karas P, Bolcková T, Streitová M, Carthel C, Coraluppi S, Harder N, Rohr K, Magnusson KE, Jaldén J, Blau HM, Dzyubachyk O, Křížek P, Hagen GM, Pastor-Escuredo D, Jimenez-Carretero D, Ledesma-Carbayo MJ, Muñoz-Barrutia A, Meijering E, Kozubek M, Ortiz-de-Solorzano C.

Bioinformatics. 2014 Jun 1;30(11):1609-17. doi: 10.1093/bioinformatics/btu080. Epub 2014 Feb 12.

34.

Objective comparison of particle tracking methods.

Chenouard N, Smal I, de Chaumont F, Maška M, Sbalzarini IF, Gong Y, Cardinale J, Carthel C, Coraluppi S, Winter M, Cohen AR, Godinez WJ, Rohr K, Kalaidzidis Y, Liang L, Duncan J, Shen H, Xu Y, Magnusson KE, Jaldén J, Blau HM, Paul-Gilloteaux P, Roudot P, Kervrann C, Waharte F, Tinevez JY, Shorte SL, Willemse J, Celler K, van Wezel GP, Dan HW, Tsai YS, Ortiz de Solórzano C, Olivo-Marin JC, Meijering E.

Nat Methods. 2014 Mar;11(3):281-9. doi: 10.1038/nmeth.2808. Epub 2014 Jan 19.

35.

Early role for IL-6 signalling during generation of induced pluripotent stem cells revealed by heterokaryon RNA-Seq.

Brady JJ, Li M, Suthram S, Jiang H, Wong WH, Blau HM.

Nat Cell Biol. 2013 Oct;15(10):1244-52. doi: 10.1038/ncb2835. Epub 2013 Sep 1.

36.

Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy.

Mourkioti F, Kustan J, Kraft P, Day JW, Zhao MM, Kost-Alimova M, Protopopov A, DePinho RA, Bernstein D, Meeker AK, Blau HM.

Nat Cell Biol. 2013 Aug;15(8):895-904. doi: 10.1038/ncb2790. Epub 2013 Jul 7.

37.

Tumor suppressors: enhancers or suppressors of regeneration?

Pomerantz JH, Blau HM.

Development. 2013 Jun;140(12):2502-12. doi: 10.1242/dev.084210.

38.

Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases.

Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, Chuah M, Cornetta K, Davies KE, Dickson JG, Duchateau P, Flotte TR, Gaudet D, Gersbach CA, Gilbert R, Glorioso J, Herzog RW, High KA, Huang W, Huard J, Joung JK, Liu D, Liu D, Lochmüller H, Lustig L, Martens J, Massie B, Mavilio F, Mendell JR, Nathwani A, Ponder K, Porteus M, Puymirat J, Samulski J, Takeda S, Thrasher A, VandenDriessche T, Wei Y, Wilson JM, Wilton SD, Wolfe JH, Gao G.

Mol Ther. 2013 Feb;21(2):266-8. doi: 10.1038/mt.2013.4. No abstract available.

39.

An immunoreceptor tyrosine-based inhibition motif in varicella-zoster virus glycoprotein B regulates cell fusion and skin pathogenesis.

Oliver SL, Brady JJ, Sommer MH, Reichelt M, Sung P, Blau HM, Arvin AM.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1911-6. doi: 10.1073/pnas.1216985110. Epub 2013 Jan 15.

40.

A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells.

Bhutani N, Decker MN, Brady JJ, Bussat RT, Burns DM, Corbel SY, Blau HM.

FASEB J. 2013 Mar;27(3):1107-13. doi: 10.1096/fj.12-222125. Epub 2012 Dec 4.

41.

Protein-engineered biomaterials to generate human skeletal muscle mimics.

Sengupta D, Gilbert PM, Johnson KJ, Blau HM, Heilshorn SC.

Adv Healthc Mater. 2012 Nov;1(6):785-9. doi: 10.1002/adhm.201200195. Epub 2012 Sep 5. No abstract available.

42.

Redefining differentiation: Reshaping our ends.

Blau HM.

Nat Cell Biol. 2012 May 30;14(6):558. doi: 10.1038/ncb2506. No abstract available.

PMID:
22643873
43.

Therapeutic angiogenesis due to balanced single-vector delivery of VEGF and PDGF-BB.

Banfi A, von Degenfeld G, Gianni-Barrera R, Reginato S, Merchant MJ, McDonald DM, Blau HM.

FASEB J. 2012 Jun;26(6):2486-97. doi: 10.1096/fj.11-197400. Epub 2012 Mar 5.

44.

A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal.

Gilbert PM, Corbel S, Doyonnas R, Havenstrite K, Magnusson KE, Blau HM.

Integr Biol (Camb). 2012 Apr;4(4):360-7. doi: 10.1039/c2ib00148a. Epub 2012 Feb 10. Review.

45.

Structure-function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism.

Vleck SE, Oliver SL, Brady JJ, Blau HM, Rajamani J, Sommer MH, Arvin AM.

Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18412-7. doi: 10.1073/pnas.1111333108. Epub 2011 Oct 24.

46.

DNA demethylation dynamics.

Bhutani N, Burns DM, Blau HM.

Cell. 2011 Sep 16;146(6):866-72. doi: 10.1016/j.cell.2011.08.042.

47.

Nanogel star polymer architectures: a nanoparticle platform for modular programmable macromolecular self-assembly, intercellular transport, and dual-mode cargo delivery.

Lee VY, Havenstrite K, Tjio M, McNeil M, Blau HM, Miller RD, Sly J.

Adv Mater. 2011 Oct 18;23(39):4509-15. doi: 10.1002/adma.201102371. Epub 2011 Sep 8. No abstract available.

48.

MicroRNA programs in normal and aberrant stem and progenitor cells.

Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, Doyonnas R, Lo MC, Perry JM, Renault VM, Sacco A, Somervaille T, Viatour P, Brunet A, Cleary ML, Li L, Sage J, Zhang DE, Blau HM, Chen C, Chen CZ.

Genome Res. 2011 May;21(5):798-810. doi: 10.1101/gr.111385.110. Epub 2011 Mar 30.

49.

Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.

Gibbs KD Jr, Gilbert PM, Sachs K, Zhao F, Blau HM, Weissman IL, Nolan GP, Majeti R.

Blood. 2011 Apr 21;117(16):4226-33. doi: 10.1182/blood-2010-07-298232. Epub 2011 Feb 28.

50.

Engineering a stem cell house into a home.

Gilbert PM, Blau HM.

Stem Cell Res Ther. 2011 Jan 31;2(1):3. doi: 10.1186/scrt44. Review.

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