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Interplay between BRCA1 and GADD45A and Its Potential for Nucleotide Excision Repair in Breast Cancer Pathogenesis.

Pietrasik S, Zajac G, Morawiec J, Soszynski M, Fila M, Blasiak J.

Int J Mol Sci. 2020 Jan 29;21(3). pii: E870. doi: 10.3390/ijms21030870. Review.


Pro- and Antioxidant Effects of Vitamin C in Cancer in correspondence to Its Dietary and Pharmacological Concentrations.

Pawlowska E, Szczepanska J, Blasiak J.

Oxid Med Cell Longev. 2019 Dec 24;2019:7286737. doi: 10.1155/2019/7286737. eCollection 2019. Review.


Senescence in the pathogenesis of age-related macular degeneration.

Blasiak J.

Cell Mol Life Sci. 2020 Mar;77(5):789-805. doi: 10.1007/s00018-019-03420-x. Epub 2020 Jan 2. Review.


Is an "Epigenetic Diet" for Migraines Justified? The Case of Folate and DNA Methylation.

Fila M, Chojnacki C, Chojnacki J, Blasiak J.

Nutrients. 2019 Nov 14;11(11). pii: E2763. doi: 10.3390/nu11112763. Review.


Expression of VEGFA-regulating miRNAs and mortality in wet AMD.

Blasiak J, Watala C, Tuuminen R, Kivinen N, Koskela A, Uusitalo-Järvinen H, Tuulonen A, Winiarczyk M, Mackiewicz J, Zmorzyński S, Filip A, Kaarniranta K.

J Cell Mol Med. 2019 Dec;23(12):8464-8471. doi: 10.1111/jcmm.14731. Epub 2019 Oct 21.


Mitochondria in migraine pathophysiology - does epigenetics play a role?

Fila M, Pawłowska E, Blasiak J.

Arch Med Sci. 2019 Jul;15(4):944-956. doi: 10.5114/aoms.2019.86061. Epub 2019 Jun 20.


Epigenetic modifiers 5-aza-2'-deoxycytidine and valproic acid differentially change viability, DNA damage and gene expression in metastatic and non-metastatic colon cancer cell lines.

Ghecham A, Senator A, Pawlowska E, Bouafia W, Błasiak J.

Acta Biochim Pol. 2019 Jul 9;66(3):355-360. doi: 10.18388/abp.2019_2814.


Can vitamin D protect against age-related macular degeneration or slow its progression?

Kaarniranta K, Pawlowska E, Szczepanska J, Jablkowska A, Błasiak J.

Acta Biochim Pol. 2019 Jun 18;66(2):147-158. doi: 10.18388/abp.2018_2810. Review.


Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD).

Kaarniranta K, Pawlowska E, Szczepanska J, Jablkowska A, Blasiak J.

Int J Mol Sci. 2019 May 14;20(10). pii: E2374. doi: 10.3390/ijms20102374. Review.


American Ginseng (Panax quinquefolium L.) as a Source of Bioactive Phytochemicals with Pro-Health Properties.

Szczuka D, Nowak A, Zakłos-Szyda M, Kochan E, Szymańska G, Motyl I, Blasiak J.

Nutrients. 2019 May 9;11(5). pii: E1041. doi: 10.3390/nu11051041. Review.


Dietary Polyphenols in Age-Related Macular Degeneration: Protection against Oxidative Stress and Beyond.

Pawlowska E, Szczepanska J, Koskela A, Kaarniranta K, Blasiak J.

Oxid Med Cell Longev. 2019 Mar 24;2019:9682318. doi: 10.1155/2019/9682318. eCollection 2019. Review.


Expression of tryptophan hydroxylase in gastric mucosa in symptomatic and asymptomatic Helicobacter pylori infection.

Chojnacki C, Popławski T, Błońska A, Błasiak J, Romanowski M, Chojnacki J.

Arch Med Sci. 2019 Mar;15(2):416-423. doi: 10.5114/aoms.2018.76928. Epub 2018 Jul 5.


Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives.

Nowak A, Zakłos-Szyda M, Błasiak J, Nowak A, Zhang Z, Zhang B.

Nutrients. 2019 Feb 4;11(2). pii: E333. doi: 10.3390/nu11020333. Review.


Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration.

Blasiak J, Pawlowska E, Szczepanska J, Kaarniranta K.

Int J Mol Sci. 2019 Jan 8;20(1). pii: E210. doi: 10.3390/ijms20010210. Review.


Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.

Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K.

Redox Biol. 2019 Jan;20:1-12. doi: 10.1016/j.redox.2018.09.011. Epub 2018 Sep 14.


PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.

Kaarniranta K, Kajdanek J, Morawiec J, Pawlowska E, Blasiak J.

Int J Mol Sci. 2018 Aug 7;19(8). pii: E2317. doi: 10.3390/ijms19082317. Review.


Anti-proliferative, pro-apoptotic and anti-oxidative activity of Lactobacillus and Bifidobacterium strains: A review of mechanisms and therapeutic perspectives.

Nowak A, Paliwoda A, Błasiak J.

Crit Rev Food Sci Nutr. 2019;59(21):3456-3467. doi: 10.1080/10408398.2018.1494539. Epub 2018 Oct 16. Review.


Mitochondrial quality control in AMD: does mitophagy play a pivotal role?

Hyttinen JMT, Viiri J, Kaarniranta K, Błasiak J.

Cell Mol Life Sci. 2018 Aug;75(16):2991-3008. doi: 10.1007/s00018-018-2843-7. Epub 2018 May 18. Review.


NF-κB-Mediated Inflammation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Does Autophagy Play a Role?

Pawlowska E, Szczepanska J, Wisniewski K, Tokarz P, Jaskólski DJ, Blasiak J.

Int J Mol Sci. 2018 Apr 19;19(4). pii: E1245. doi: 10.3390/ijms19041245. Review.


An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.

Pawlowska E, Szczepanska J, Szatkowska M, Blasiak J.

Int J Mol Sci. 2018 Mar 17;19(3). pii: E889. doi: 10.3390/ijms19030889. Review.


The Long Noncoding RNA HOTAIR in Breast Cancer: Does Autophagy Play a Role?

Pawłowska E, Szczepanska J, Blasiak J.

Int J Mol Sci. 2017 Nov 3;18(11). pii: E2317. doi: 10.3390/ijms18112317. Review.


Evaluation of Melatonin Secretion and Metabolism Exponents in Patients with Ulcerative and Lymphocytic Colitis.

Chojnacki C, Błasiak J, Fichna J, Chojnacki J, Popławski T.

Molecules. 2018 Jan 29;23(2). pii: E272. doi: 10.3390/molecules23020272.


Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?

Blasiak J, Piechota M, Pawlowska E, Szatkowska M, Sikora E, Kaarniranta K.

Oxid Med Cell Longev. 2017;2017:5293258. doi: 10.1155/2017/5293258. Epub 2017 Nov 1. Review.


Biomolecular computers with multiple restriction enzymes.

Sakowski S, Krasinski T, Waldmajer J, Sarnik J, Blasiak J, Poplawski T.

Genet Mol Biol. 2017 Oct-Dec;40(4):860-870. doi: 10.1590/1678-4685-GMB-2016-0132. Epub 2017 Oct 23.


DNA2-An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?

Pawłowska E, Szczepanska J, Blasiak J.

Int J Mol Sci. 2017 Jul 18;18(7). pii: E1562. doi: 10.3390/ijms18071562. Review.


A detailed experimental study of a DNA computer with two endonucleases.

Sakowski S, Krasiński T, Sarnik J, Blasiak J, Waldmajer J, Poplawski T.

Z Naturforsch C J Biosci. 2017 Jul 14;72(7-8):303-313. doi: 10.1515/znc-2016-0137.


The significance of DNA methylation profile in metastasis-related genes for the progression of colorectal cancer.

Tokarz P, Pawlowska E, Bialkowska-Warzecha J, Blasiak J.

Cell Mol Biol (Noisy-le-grand). 2017 Feb 28;63(2):79-87. doi: 10.14715/cmb/2017.63.2.12. Review.


DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD).

Hyttinen JMT, Błasiak J, Niittykoski M, Kinnunen K, Kauppinen A, Salminen A, Kaarniranta K.

Ageing Res Rev. 2017 Jul;36:64-77. doi: 10.1016/j.arr.2017.03.006. Epub 2017 Mar 27. Review.


DNA-Damaging Anticancer Drugs - A Perspective for DNA Repair- Oriented Therapy.

Blasiak J.

Curr Med Chem. 2017;24(15):1488-1503. doi: 10.2174/0929867324666170124145557. Review.


Reactive oxygen species in BCR-ABL1-expressing cells - relevance to chronic myeloid leukemia.

Antoszewska-Smith J, Pawlowska E, Blasiak J.

Acta Biochim Pol. 2017;64(1):1-10. doi: 10.18388/abp.2016_1396. Epub 2016 Dec 1. Review.


Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration.

Kaarniranta K, Tokarz P, Koskela A, Paterno J, Blasiak J.

Cell Biol Toxicol. 2017 Apr;33(2):113-128. doi: 10.1007/s10565-016-9371-8. Epub 2016 Nov 29. Review.


Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration.

Blasiak J, Reiter RJ, Kaarniranta K.

Oxid Med Cell Longev. 2016;2016:6819736. Epub 2016 Sep 5. Review.


All-Trans Retinoic Acid Modulates DNA Damage Response and the Expression of the VEGF-A and MKI67 Genes in ARPE-19 Cells Subjected to Oxidative Stress.

Tokarz P, Piastowska-Ciesielska AW, Kaarniranta K, Blasiak J.

Int J Mol Sci. 2016 Jun 14;17(6). pii: E898. doi: 10.3390/ijms17060898.


Expression and variability of lipid metabolism genes in intracranial aneurysm.

Synowiec E, Wojcik KA, Wójcik R, Wiśniewski K, Fila M, Tokarz P, Bieńkowski M, Jaskolski D, Blasiak J.

Cell Mol Biol (Noisy-le-grand). 2016 Apr 30;62(4):73-82.


Nucleotide Excision Repair and Vitamin D--Relevance for Skin Cancer Therapy.

Pawlowska E, Wysokinski D, Blasiak J.

Int J Mol Sci. 2016 Apr 6;17(4):372. doi: 10.3390/ijms17040372. Review.


Inhibition of DNA methyltransferase or histone deacetylase protects retinal pigment epithelial cells from DNA damage induced by oxidative stress by the stimulation of antioxidant enzymes.

Tokarz P, Kaarniranta K, Blasiak J.

Eur J Pharmacol. 2016 Apr 5;776:167-75. doi: 10.1016/j.ejphar.2016.02.049. Epub 2016 Feb 17.


Inflammation and its role in age-related macular degeneration.

Kauppinen A, Paterno JJ, Blasiak J, Salminen A, Kaarniranta K.

Cell Mol Life Sci. 2016 May;73(9):1765-86. doi: 10.1007/s00018-016-2147-8. Epub 2016 Feb 6. Review.


Mitochondrial mutagenesis in BCR-ABL1-expressing cells sensitive and resistant to imatinib.

Blasiak J, Hoser G, Bialkowska-Warzecha J, Pawlowska E, Skorski T.

Acta Biochim Pol. 2016;63(2):365-70. doi: 10.18388/abp.2015_1189. Epub 2016 Jan 12.


Doxorubicin Differentially Induces Apoptosis, Expression of Mitochondrial Apoptosis-Related Genes, and Mitochondrial Potential in BCR-ABL1-Expressing Cells Sensitive and Resistant to Imatinib.

Synowiec E, Hoser G, Bialkowska-Warzecha J, Pawlowska E, Skorski T, Blasiak J.

Biomed Res Int. 2015;2015:673512. doi: 10.1155/2015/673512. Epub 2015 Nov 4.


DNA Repair--A Double-Edged Sword in the Genomic Stability of Cancer Cells--The Case of Chronic Myeloid Leukemia.

Pawlowska E, Blasiak J.

Int J Mol Sci. 2015 Nov 18;16(11):27535-49. doi: 10.3390/ijms161126049. Review.


Lack of association between polymorphisms of the DNA base excision repair genes MUTYH and hOGG1 and keratoconus in a Polish subpopulation.

Synowiec E, Wójcik KA, Czubatka A, Polakowski P, Izdebska J, Szaflik J, Błasiak J, Szaflik JP.

Arch Med Sci. 2015 Oct 12;11(5):1101-10. doi: 10.5114/aoms.2015.54867.


Role of RUNX2 in Breast Carcinogenesis.

Wysokinski D, Blasiak J, Pawlowska E.

Int J Mol Sci. 2015 Sep 2;16(9):20969-93. doi: 10.3390/ijms160920969. Review.


Variation in DNA Base Excision Repair Genes in Fuchs Endothelial Corneal Dystrophy.

Wójcik KA, Synowiec E, Polakowski P, Błasiak J, Szaflik J, Szaflik JP.

Med Sci Monit. 2015 Sep 21;21:2809-27. doi: 10.12659/MSM.894273.


Reactive Oxygen Species and Mitochondrial DNA Damage and Repair in BCR-ABL1 Cells Resistant to Imatinib.

Blasiak J, Hoser G, Bialkowska-Warzecha J, Pawlowska E, Skorski T.

Biores Open Access. 2015 Jul 1;4(1):334-42. doi: 10.1089/biores.2015.0022. eCollection 2015.


UV Differentially Induces Oxidative Stress, DNA Damage and Apoptosis in BCR-ABL1-Positive Cells Sensitive and Resistant to Imatinib.

Synowiec E, Hoser G, Wojcik K, Pawlowska E, Skorski T, Błasiak J.

Int J Mol Sci. 2015 Aug 5;16(8):18111-28. doi: 10.3390/ijms160818111.


Role of the Cell Cycle Re-Initiation in DNA Damage Response of Post-Mitotic Cells and Its Implication in the Pathogenesis of Neurodegenerative Diseases.

Tokarz P, Kaarniranta K, Blasiak J.

Rejuvenation Res. 2016 Apr;19(2):131-9. doi: 10.1089/rej.2015.1717. Epub 2016 Jan 27.


Polymorphism of the APEX nuclease 1 gene in keratoconus and Fuchs endothelial corneal dystrophy.

Wojcik KA, Synowiec E, Kaminska A, Izdebska J, Polakowski P, Pawlowska E, Blasiak J, Szaflik J, Szaflik JP.

Cell Mol Biol Lett. 2015 Mar;20(1):48-65. doi: 10.1515/cmble-2015-0001.


Transferrin receptor levels and polymorphism of its gene in age-related macular degeneration.

Wysokinski D, Danisz K, Pawlowska E, Dorecka M, Romaniuk D, Robaszkiewicz J, Szaflik M, Szaflik J, Blasiak J, Szaflik JP.

Acta Biochim Pol. 2015;62(2):177-84. doi: 10.18388/abp.2014_843. Epub 2015 Apr 27.


Polymorphism of the LIG3 gene in keratoconus and Fuchs endothelial corneal dystrophy.

Synowiec E, Wojcik KA, Izdebska J, Binczyk E, Szaflik J, Blasiak J, Szaflik JP.

Cell Mol Biol (Noisy-le-grand). 2015 Mar 28;61(1):56-63.


Polymorphism of DNA mismatch repair genes in endometrial cancer.

Poplawski T, Sobczuk A, Sarnik J, Pawlowska E, Blasiak J.

Exp Oncol. 2015 Mar;37(1):44-7.


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