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Items: 44

1.

The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors.

Pandhare A, Pappu AS, Wilms H, Blanton MP, Jansen M.

Neuropharmacology. 2017 Feb;113(Pt A):89-99. doi: 10.1016/j.neuropharm.2016.09.021. Epub 2016 Sep 24.

2.

Nicotine Toxicity in a Nursing Home Resident With Dementia Secondary to Nicotine Replacement Treatment.

Khan S, Blanton MP, Chavez M.

Prim Care Companion CNS Disord. 2016 Jun 30;18(3). doi: 10.4088/PCC.15l01882. eCollection 2016. No abstract available.

3.

The monomeric state of the proton-coupled folate transporter represents the functional unit in the plasma membrane.

Duddempudi PK, Nakashe P, Blanton MP, Jansen M.

FEBS J. 2013 Jun;280(12):2900-15. doi: 10.1111/febs.12293. Epub 2013 May 28.

4.

Structural sensitivity of a prokaryotic pentameric ligand-gated ion channel to its membrane environment.

Labriola JM, Pandhare A, Jansen M, Blanton MP, Corringer PJ, Baenziger JE.

J Biol Chem. 2013 Apr 19;288(16):11294-303. doi: 10.1074/jbc.M113.458133. Epub 2013 Mar 5.

5.

Bupropion binds to two sites in the Torpedo nicotinic acetylcholine receptor transmembrane domain: a photoaffinity labeling study with the bupropion analogue [(125)I]-SADU-3-72.

Pandhare A, Hamouda AK, Staggs B, Aggarwal S, Duddempudi PK, Lever JR, Lapinsky DJ, Jansen M, Cohen JB, Blanton MP.

Biochemistry. 2012 Mar 27;51(12):2425-35. doi: 10.1021/bi300101r. Epub 2012 Mar 15.

6.

(±)-2-(N-tert-Butylamino)-3'-[(125)I]-iodo-4'-azidopropiophenone: a dopamine transporter and nicotinic acetylcholine receptor photoaffinity ligand based on bupropion (Wellbutrin, Zyban).

Lapinsky DJ, Aggarwal S, Nolan TL, Surratt CK, Lever JR, Acharya R, Vaughan RA, Pandhare A, Blanton MP.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):523-6. doi: 10.1016/j.bmcl.2011.10.086. Epub 2011 Nov 4.

7.

Structural characterization and agonist binding to human α4β2 nicotinic receptors.

daCosta CJ, Michel Sturgeon R, Hamouda AK, Blanton MP, Baenziger JE.

Biochem Biophys Res Commun. 2011 Apr 15;407(3):456-60. doi: 10.1016/j.bbrc.2011.03.026. Epub 2011 Mar 17.

PMID:
21396349
8.

Hydrophobic photolabeling studies identify the lipid-protein interface of the 5-HT3A receptor.

Sanghvi M, Hamouda AK, Davis MI, Morton RA, Srivastava S, Pandhare A, Duddempudi PK, Machu TK, Lovinger DM, Cohen JB, Blanton MP.

Biochemistry. 2009 Oct 6;48(39):9278-86. doi: 10.1021/bi901208j.

9.

Palmitoylation of nicotinic acetylcholine receptors.

Alexander JK, Govind AP, Drisdel RC, Blanton MP, Vallejo Y, Lam TT, Green WN.

J Mol Neurosci. 2010 Jan;40(1-2):12-20. doi: 10.1007/s12031-009-9246-z. Epub 2009 Aug 20.

10.

[(3)H]Epibatidine photolabels non-equivalent amino acids in the agonist binding site of Torpedo and alpha4beta2 nicotinic acetylcholine receptors.

Srivastava S, Hamouda AK, Pandhare A, Duddempudi PK, Sanghvi M, Cohen JB, Blanton MP.

J Biol Chem. 2009 Sep 11;284(37):24939-47. doi: 10.1074/jbc.M109.019083. Epub 2009 Jul 20.

11.

Photoaffinity labeling the agonist binding domain of alpha4beta4 and alpha4beta2 neuronal nicotinic acetylcholine receptors with [(125)I]epibatidine and 5[(125)I]A-85380.

Hamouda AK, Jin X, Sanghvi M, Srivastava S, Pandhare A, Duddempudi PK, Steinbach JH, Blanton MP.

Biochim Biophys Acta. 2009 Sep;1788(9):1987-95. doi: 10.1016/j.bbamem.2009.06.012. Epub 2009 Jun 21.

12.

Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors.

Arias HR, Xing H, Macdougall K, Blanton MP, Soti F, Kem WR.

Br J Pharmacol. 2009 May;157(2):320-30. doi: 10.1111/j.1476-5381.2009.00156.x. Epub 2009 Mar 26.

13.

Probing the structure of the affinity-purified and lipid-reconstituted torpedo nicotinic acetylcholine receptor.

Hamouda AK, Chiara DC, Blanton MP, Cohen JB.

Biochemistry. 2008 Dec 2;47(48):12787-94. doi: 10.1021/bi801476j.

14.

Identifying the binding site(s) for antidepressants on the Torpedo nicotinic acetylcholine receptor: [3H]2-azidoimipramine photolabeling and molecular dynamics studies.

Sanghvi M, Hamouda AK, Jozwiak K, Blanton MP, Trudell JR, Arias HR.

Biochim Biophys Acta. 2008 Dec;1778(12):2690-9. doi: 10.1016/j.bbamem.2008.08.019. Epub 2008 Sep 10.

15.
16.

Assessing the lipid requirements of the Torpedo californica nicotinic acetylcholine receptor.

Hamouda AK, Sanghvi M, Sauls D, Machu TK, Blanton MP.

Biochemistry. 2006 Apr 4;45(13):4327-37.

18.

Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: electrophysiology-coordinated photochemistry and mass spectrometry.

Leite JF, Blanton MP, Shahgholi M, Dougherty DA, Lester HA.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):13054-9. Epub 2003 Oct 20.

19.
20.

Unique general anesthetic binding sites within distinct conformational states of the nicotinic acetylcholine receptor.

Arias HR, Kem WR, Trudell JR, Blanton MP.

Int Rev Neurobiol. 2003;54:1-50. Review.

PMID:
12785284
21.
22.

Allosterically linked noncompetitive antagonist binding sites in the resting nicotinic acetylcholine receptor ion channel.

Arias HR, McCardy EA, Bayer EZ, Gallagher MJ, Blanton MP.

Arch Biochem Biophys. 2002 Jul 1;403(1):121-31.

PMID:
12061809
23.

Lipid-protein interactions at the nicotinic acetylcholine receptor. A functional coupling between nicotinic receptors and phosphatidic acid-containing lipid bilayers.

daCosta CJ, Ogrel AA, McCardy EA, Blanton MP, Baenziger JE.

J Biol Chem. 2002 Jan 4;277(1):201-8. Epub 2001 Oct 26.

24.

Interaction of barbiturate analogs with the Torpedo californica nicotinic acetylcholine receptor ion channel.

Arias HR, McCardy EA, Gallagher MJ, Blanton MP.

Mol Pharmacol. 2001 Sep;60(3):497-506.

PMID:
11502880
26.

Structure of the pore-forming transmembrane domain of a ligand-gated ion channel.

Méthot N, Ritchie BD, Blanton MP, Baenziger JE.

J Biol Chem. 2001 Jun 29;276(26):23726-32. Epub 2001 Apr 27.

27.

Characterization of the dizocilpine binding site on the nicotinic acetylcholine receptor.

Arias HR, McCardy EA, Blanton MP.

Mol Pharmacol. 2001 May;59(5):1051-60.

PMID:
11306687
28.

Alpha-conotoxins.

Arias HR, Blanton MP.

Int J Biochem Cell Biol. 2000 Oct;32(10):1017-28. Review.

PMID:
11091135
29.

A conformational intermediate between the resting and desensitized states of the nicotinic acetylcholine receptor.

Ryan SE, Blanton MP, Baenziger JE.

J Biol Chem. 2001 Feb 16;276(7):4796-803. Epub 2000 Nov 16.

31.

Topography of nicotinic acetylcholine receptor membrane-embedded domains.

Barrantes FJ, Antollini SS, Blanton MP, Prieto M.

J Biol Chem. 2000 Dec 1;275(48):37333-9.

32.

5-hydroxytryptamine interaction with the nicotinic acetylcholine receptor.

Blanton MP, McCardy EA, Fryer JD, Liu M, Lukas RJ.

Eur J Pharmacol. 2000 Feb 18;389(2-3):155-63.

PMID:
10688979
33.
35.
36.

Identifying the cholesterol binding domain in the nicotinic acetylcholine receptor with [125I]azido-cholesterol.

Corbin J, Wang HH, Blanton MP.

Biochim Biophys Acta. 1998 Nov 11;1414(1-2):65-74.

37.
38.
41.
42.

Mapping the lipid-exposed regions in the Torpedo californica nicotinic acetylcholine receptor.

Blanton MP, Cohen JB.

Biochemistry. 1992 Apr 21;31(15):3738-50. Erratum in: Biochemistry 1992 Jun 30;31(25):5951.

PMID:
1567828

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