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Items: 33

1.

The level of synovial AXL expression determines the outcome of inflammatory arthritis, possibly depending on the upstream role of TGF-β1.

Waterborg CEJ, Broeren MGA, Blaney Davidson EN, Koenders MI, van Lent PLEM, van den Berg WB, van der Kraan PM, van de Loo FAJ.

Rheumatology (Oxford). 2019 Mar 1;58(3):536-546. doi: 10.1093/rheumatology/key337.

PMID:
30508140
2.

IL-37 diminishes proteoglycan loss in human OA cartilage: donor-specific link between IL-37 and MMP-3.

van Geffen EW, van Caam APM, Schreurs W, van de Loo FA, van Lent PLEM, Koenders MI, Thudium CS, Bay-Jensen AC, Blaney Davidson EN, van der Kraan PM.

Osteoarthritis Cartilage. 2019 Jan;27(1):148-157. doi: 10.1016/j.joca.2018.08.016. Epub 2018 Sep 7.

PMID:
30201492
3.

Identification of TGFβ-related genes regulated in murine osteoarthritis and chondrocyte hypertrophy by comparison of multiple microarray datasets.

de Kroon LMG, van den Akker GGH, Brachvogel B, Narcisi R, Belluoccio D, Jenner F, Bateman JF, Little CB, Brama PAJ, Blaney Davidson EN, van der Kraan PM, van Osch GJVM.

Bone. 2018 Nov;116:67-77. doi: 10.1016/j.bone.2018.07.008. Epub 2018 Jul 21.

PMID:
30010080
4.

Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation.

Broeren MGA, Di Ceglie I, Bennink MB, van Lent PLEM, van den Berg WB, Koenders MI, Blaney Davidson EN, van der Kraan PM, van de Loo FAJ.

PeerJ. 2018 May 30;6:e4771. doi: 10.7717/peerj.4771. eCollection 2018.

5.

Interleukin 1 β-induced SMAD2/3 linker modifications are TAK1 dependent and delay TGFβ signaling in primary human mesenchymal stem cells.

van den Akker GG, van Beuningen HM, Vitters EL, Koenders MI, van de Loo FA, van Lent PL, Blaney Davidson EN, van der Kraan PM.

Cell Signal. 2017 Dec;40:190-199. doi: 10.1016/j.cellsig.2017.09.010. Epub 2017 Sep 21.

PMID:
28943409
6.

SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells.

de Kroon LM, Narcisi R, van den Akker GG, Vitters EL, Blaney Davidson EN, van Osch GJ, van der Kraan PM.

Sci Rep. 2017 Feb 27;7:43164. doi: 10.1038/srep43164.

7.

Osteoarthritis year in review 2016: biology.

Blaney Davidson EN, van Caam AP, van der Kraan PM.

Osteoarthritis Cartilage. 2017 Feb;25(2):175-180. doi: 10.1016/j.joca.2016.09.024. Epub 2017 Jan 16. Review.

8.

IL37 dampens the IL1β-induced catabolic status of human OA chondrocytes.

van Geffen EW, van Caam AP, van Beuningen HM, Vitters EL, Schreurs W, van de Loo FA, van Lent PL, Koenders MI, Blaney Davidson EN, van der Kraan PM.

Rheumatology (Oxford). 2017 Mar 1;56(3):351-361. doi: 10.1093/rheumatology/kew411.

PMID:
27940589
9.

Milk extracellular vesicles accelerate osteoblastogenesis but impair bone matrix formation.

Oliveira MC, Arntz OJ, Blaney Davidson EN, van Lent PL, Koenders MI, van der Kraan PM, van den Berg WB, Ferreira AV, van de Loo FA.

J Nutr Biochem. 2016 Apr;30:74-84. doi: 10.1016/j.jnutbio.2015.11.017. Epub 2015 Dec 28.

PMID:
27012623
10.

Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.

de Kroon LM, Narcisi R, Blaney Davidson EN, Cleary MA, van Beuningen HM, Koevoet WJ, van Osch GJ, van der Kraan PM.

PLoS One. 2015 Dec 31;10(12):e0146124. doi: 10.1371/journal.pone.0146124. eCollection 2015.

11.

Unravelling osteoarthritis-related synovial fibrosis: a step closer to solving joint stiffness.

Remst DF, Blaney Davidson EN, van der Kraan PM.

Rheumatology (Oxford). 2015 Nov;54(11):1954-63. doi: 10.1093/rheumatology/kev228. Epub 2015 Jul 13. Review.

PMID:
26175472
12.

TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

Blaney Davidson EN, van Caam AP, Vitters EL, Bennink MB, Thijssen E, van den Berg WB, Koenders MI, van Lent PL, van de Loo FA, van der Kraan PM.

Osteoarthritis Cartilage. 2015 Mar;23(3):478-86. doi: 10.1016/j.joca.2014.12.005. Epub 2014 Dec 18.

13.

How to build an inducible cartilage-specific transgenic mouse.

Blaney Davidson EN, van de Loo FA, van den Berg WB, van der Kraan PM.

Arthritis Res Ther. 2014;16(3):210. Review.

14.

Physiological and excessive mechanical compression of articular cartilage activates Smad2/3P signaling.

Madej W, van Caam A, Blaney Davidson EN, van der Kraan PM, Buma P.

Osteoarthritis Cartilage. 2014 Jul;22(7):1018-25. doi: 10.1016/j.joca.2014.04.024. Epub 2014 May 2.

15.

Gene expression analysis of murine and human osteoarthritis synovium reveals elevation of transforming growth factor β-responsive genes in osteoarthritis-related fibrosis.

Remst DF, Blom AB, Vitters EL, Bank RA, van den Berg WB, Blaney Davidson EN, van der Kraan PM.

Arthritis Rheumatol. 2014 Mar;66(3):647-56. doi: 10.1002/art.38266.

16.

Canonical Wnt signaling skews TGF-β signaling in chondrocytes towards signaling via ALK1 and Smad 1/5/8.

van den Bosch MH, Blom AB, van Lent PL, van Beuningen HM, Blaney Davidson EN, van der Kraan PM, van den Berg WB.

Cell Signal. 2014 May;26(5):951-8. doi: 10.1016/j.cellsig.2014.01.021. Epub 2014 Jan 23.

PMID:
24463008
17.

Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage.

Blaney Davidson EN, Vitters EL, Bennink MB, van Lent PL, van Caam AP, Blom AB, van den Berg WB, van de Loo FA, van der Kraan PM.

Ann Rheum Dis. 2015 Jun;74(6):1257-64. doi: 10.1136/annrheumdis-2013-204528. Epub 2014 Jan 21.

PMID:
24448347
18.

TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling.

Remst DF, Blaney Davidson EN, Vitters EL, Bank RA, van den Berg WB, van der Kraan PM.

Cell Tissue Res. 2014 Jan;355(1):163-71. doi: 10.1007/s00441-013-1740-5. Epub 2013 Nov 6.

PMID:
24192939
19.

Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression.

Remst DF, Blaney Davidson EN, Vitters EL, Blom AB, Stoop R, Snabel JM, Bank RA, van den Berg WB, van der Kraan PM.

Osteoarthritis Cartilage. 2013 Jan;21(1):157-64. doi: 10.1016/j.joca.2012.10.002. Epub 2012 Oct 13.

20.

Acute acetaminophen intoxication leads to hepatic iron loading by decreased hepcidin synthesis.

van Swelm RP, Laarakkers CM, Blous L, Peters JG, Blaney Davidson EN, van der Kraan PM, Swinkels DW, Masereeuw R, Russel FG.

Toxicol Sci. 2012 Sep;129(1):225-33. doi: 10.1093/toxsci/kfs176. Epub 2012 May 18.

PMID:
22610607
21.

The RNA-binding protein human antigen R controls global changes in gene expression during Schwann cell development.

Iruarrizaga-Lejarreta M, Varela-Rey M, Lozano JJ, Fernández-Ramos D, Rodríguez-Ezpeleta N, Embade N, Lu SC, van der Kraan PM, Blaney Davidson EN, Gorospe M, Mirsky R, Jessen KR, Aransay AM, Mato JM, Martínez-Chantar ML, Woodhoo A.

J Neurosci. 2012 Apr 4;32(14):4944-58. doi: 10.1523/JNEUROSCI.5868-11.2012.

22.

Catabolic factors and osteoarthritis-conditioned medium inhibit chondrogenesis of human mesenchymal stem cells.

Heldens GT, Blaney Davidson EN, Vitters EL, Schreurs BW, Piek E, van den Berg WB, van der Kraan PM.

Tissue Eng Part A. 2012 Jan;18(1-2):45-54. doi: 10.1089/ten.TEA.2011.0083. Epub 2011 Oct 17.

PMID:
21770865
23.

Bone morphogenetic proteins and articular cartilage: To serve and protect or a wolf in sheep clothing's?

van der Kraan PM, Blaney Davidson EN, van den Berg WB.

Osteoarthritis Cartilage. 2010 Jun;18(6):735-41. doi: 10.1016/j.joca.2010.03.001. Epub 2010 Mar 6. Review.

24.

A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis.

van der Kraan PM, Blaney Davidson EN, van den Berg WB.

Arthritis Res Ther. 2010;12(1):201. doi: 10.1186/ar2896. Epub 2010 Jan 29. Review.

25.

TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: modulation and integration of signaling pathways through receptor-Smads.

van der Kraan PM, Blaney Davidson EN, Blom A, van den Berg WB.

Osteoarthritis Cartilage. 2009 Dec;17(12):1539-45. doi: 10.1016/j.joca.2009.06.008. Epub 2009 Jun 26. Review.

26.

Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.

Blaney Davidson EN, Remst DF, Vitters EL, van Beuningen HM, Blom AB, Goumans MJ, van den Berg WB, van der Kraan PM.

J Immunol. 2009 Jun 15;182(12):7937-45. doi: 10.4049/jimmunol.0803991. Erratum in: J Immunol. 2010 Aug 15;185(4):2629.

27.

Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation.

Blaney Davidson EN, Vitters EL, van Beuningen HM, van de Loo FA, van den Berg WB, van der Kraan PM.

Arthritis Rheum. 2007 Dec;56(12):4065-73.

28.

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.

Blaney Davidson EN, Vitters EL, van Lent PL, van de Loo FA, van den Berg WB, van der Kraan PM.

Arthritis Res Ther. 2007;9(5):R102.

29.

TGF-beta and osteoarthritis.

Blaney Davidson EN, van der Kraan PM, van den Berg WB.

Osteoarthritis Cartilage. 2007 Jun;15(6):597-604. Epub 2007 Mar 27. Review.

30.

Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage.

Blaney Davidson EN, Vitters EL, Mooren FM, Oliver N, Berg WB, van der Kraan PM.

Arthritis Rheum. 2006 May;54(5):1653-61.

31.

TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7.

Blaney Davidson EN, Vitters EL, van den Berg WB, van der Kraan PM.

Arthritis Res Ther. 2006;8(3):R65. Epub 2006 Mar 29.

33.

Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity.

Blaney Davidson EN, Scharstuhl A, Vitters EL, van der Kraan PM, van den Berg WB.

Arthritis Res Ther. 2005;7(6):R1338-47. Epub 2005 Sep 30.

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