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Items: 1 to 50 of 107

1.

Long-term engraftment of human cardiomyocytes combined with biodegradable microparticles induces heart repair.

Saludas L, Garbayo E, Mazo M, Pelacho B, Abizanda G, Iglesias Garcia O, Raya A, Prosper F, Blanco-Prieto MJ.

J Pharmacol Exp Ther. 2019 Feb 6. pii: jpet.118.256065. doi: 10.1124/jpet.118.256065. [Epub ahead of print]

2.

Therapeutic opportunities in neuroblastoma using nanotechnology.

Rodriguez-Nogales C, Noguera R, Patrick C, Blanco-Prieto MJJ.

J Pharmacol Exp Ther. 2019 Jan 11. pii: jpet.118.255067. doi: 10.1124/jpet.118.255067. [Epub ahead of print]

3.

Advances in Parkinson's Disease: 200 Years Later.

Del Rey NL, Quiroga-Varela A, Garbayo E, Carballo-Carbajal I, Fernández-Santiago R, Monje MHG, Trigo-Damas I, Blanco-Prieto MJ, Blesa J.

Front Neuroanat. 2018 Dec 14;12:113. doi: 10.3389/fnana.2018.00113. eCollection 2018. Review.

4.

Micro- and nanotechnology approaches to improve Parkinson's disease therapy.

Torres-Ortega PV, Saludas L, Hanafy AS, Garbayo E, Blanco-Prieto MJ.

J Control Release. 2019 Feb 10;295:201-213. doi: 10.1016/j.jconrel.2018.12.036. Epub 2018 Dec 21. Review.

PMID:
30579984
5.

NRG1 PLGA MP locally induce macrophage polarisation toward a regenerative phenotype in the heart after acute myocardial infarction.

Pascual-Gil S, Abizanda G, Iglesias E, Garbayo E, Prósper F, Blanco-Prieto MJ.

J Drug Target. 2018 Oct 17:1-9. doi: 10.1080/1061186X.2018.1531417. [Epub ahead of print]

PMID:
30289743
6.

Biocompatible porous metal-organic framework nanoparticles based on Fe or Zr for gentamicin vectorization.

Unamuno X, Imbuluzqueta E, Salles F, Horcajada P, Blanco-Prieto MJ.

Eur J Pharm Biopharm. 2018 Nov;132:11-18. doi: 10.1016/j.ejpb.2018.08.013. Epub 2018 Sep 1.

PMID:
30179739
7.

Nanomedicines for Pediatric Cancers.

Rodríguez-Nogales C, González-Fernández Y, Aldaz A, Couvreur P, Blanco-Prieto MJ.

ACS Nano. 2018 Aug 28;12(8):7482-7496. doi: 10.1021/acsnano.8b03684. Epub 2018 Aug 7.

PMID:
30071163
8.

Oral administration of edelfosine encapsulated lipid nanoparticles causes regression of lung metastases in pre-clinical models of osteosarcoma.

González-Fernández Y, Brown HK, Patiño-García A, Heymann D, Blanco-Prieto MJ.

Cancer Lett. 2018 Aug 28;430:193-200. doi: 10.1016/j.canlet.2018.05.030. Epub 2018 May 23.

9.

Phase behaviour, micellar structure and linear rheology of tetrablock copolymer Tetronic 908.

Puig-Rigall J, Obregon-Gomez I, Monreal-Pérez P, Radulescu A, Blanco-Prieto MJ, Dreiss CA, González-Gaitano G.

J Colloid Interface Sci. 2018 Aug 15;524:42-51. doi: 10.1016/j.jcis.2018.03.096. Epub 2018 Mar 29.

PMID:
29631218
10.

Heart tissue repair and cardioprotection using drug delivery systems.

Saludas L, Pascual-Gil S, Roli F, Garbayo E, Blanco-Prieto MJ.

Maturitas. 2018 Apr;110:1-9. doi: 10.1016/j.maturitas.2018.01.011. Epub 2018 Jan 13. Review.

PMID:
29563026
11.

Breaching barriers in glioblastoma. Part II: Targeted drug delivery and lipid nanoparticles.

Miranda A, Blanco-Prieto MJ, Sousa J, Pais A, Vitorino C.

Int J Pharm. 2017 Oct 5;531(1):389-410. doi: 10.1016/j.ijpharm.2017.07.049. Epub 2017 Aug 9. Review.

PMID:
28801108
12.

Effectiveness of nanoencapsulated methotrexate against osteosarcoma cells: in vitro cytotoxicity under dynamic conditions.

Mitxelena-Iribarren O, Hisey CL, Errazquin-Irigoyen M, González-Fernández Y, Imbuluzqueta E, Mujika M, Blanco-Prieto MJ, Arana S.

Biomed Microdevices. 2017 Jun;19(2):35. doi: 10.1007/s10544-017-0177-0.

PMID:
28432531
13.

Special issue on biomaterials for tissue engineering.

Blanco-Prieto MJ, Garbayo E.

Int J Pharm. 2017 May 25;523(2):439-440. doi: 10.1016/j.ijpharm.2017.02.040. Epub 2017 Feb 20. No abstract available.

PMID:
28219633
14.

Transplantation of adipose-derived stem cells combined with neuregulin-microparticles promotes efficient cardiac repair in a rat myocardial infarction model.

Díaz-Herráez P, Saludas L, Pascual-Gil S, Simón-Yarza T, Abizanda G, Prósper F, Garbayo E, Blanco-Prieto MJ.

J Control Release. 2017 Mar 10;249:23-31. doi: 10.1016/j.jconrel.2017.01.026. Epub 2017 Jan 19.

PMID:
28111317
15.

Doxorubicin and edelfosine lipid nanoparticles are effective acting synergistically against drug-resistant osteosarcoma cancer cells.

González-Fernández Y, Imbuluzqueta E, Zalacain M, Mollinedo F, Patiño-García A, Blanco-Prieto MJ.

Cancer Lett. 2017 Mar 1;388:262-268. doi: 10.1016/j.canlet.2016.12.012. Epub 2016 Dec 18.

PMID:
27998763
16.

Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges.

Wen MM, El-Salamouni NS, El-Refaie WM, Hazzah HA, Ali MM, Tosi G, Farid RM, Blanco-Prieto MJ, Billa N, Hanafy AS.

J Control Release. 2017 Jan 10;245:95-107. doi: 10.1016/j.jconrel.2016.11.025. Epub 2016 Nov 23. Review.

PMID:
27889394
17.

Development and characterization of polo-like kinase 2 loaded nanoparticles-A novel strategy for (serine-129) phosphorylation of alpha-synuclein.

Rodríguez-Nogales C, Garbayo E, Martínez-Valbuena I, Sebastián V, Luquin MR, Blanco-Prieto MJ.

Int J Pharm. 2016 Nov 30;514(1):142-149. doi: 10.1016/j.ijpharm.2016.06.044.

PMID:
27863657
18.

Cytokine-loaded PLGA and PEG-PLGA microparticles showed similar heart regeneration in a rat myocardial infarction model.

Pascual-Gil S, Simón-Yarza T, Garbayo E, Prósper F, Blanco-Prieto MJ.

Int J Pharm. 2017 May 25;523(2):531-533. doi: 10.1016/j.ijpharm.2016.11.022. Epub 2016 Nov 9.

PMID:
27838293
19.

Brain delivery of microencapsulated GDNF induces functional and structural recovery in parkinsonian monkeys.

Garbayo E, Ansorena E, Lana H, Carmona-Abellan MD, Marcilla I, Lanciego JL, Luquin MR, Blanco-Prieto MJ.

Biomaterials. 2016 Dec;110:11-23. doi: 10.1016/j.biomaterials.2016.09.015. Epub 2016 Sep 21.

PMID:
27697668
20.

Clinical advances of nanocarrier-based cancer therapy and diagnostics.

Luque-Michel E, Imbuluzqueta E, Sebastián V, Blanco-Prieto MJ.

Expert Opin Drug Deliv. 2017 Jan;14(1):75-92. Epub 2016 Jul 7. Review.

PMID:
27339650
21.

Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion.

Garbayo E, Gavira JJ, de Yebenes MG, Pelacho B, Abizanda G, Lana H, Blanco-Prieto MJ, Prosper F.

Sci Rep. 2016 May 17;6:25932. doi: 10.1038/srep25932.

22.

Cyclosporine A-loaded lipid nanoparticles in inflammatory bowel disease.

Guada M, Beloqui A, Alhouayek M, Muccioli GG, Dios-Viéitez Mdel C, Préat V, Blanco-Prieto MJ.

Int J Pharm. 2016 Apr 30;503(1-2):196-8. doi: 10.1016/j.ijpharm.2016.03.012. Epub 2016 Mar 10.

PMID:
26972380
23.

Cyclosporine A lipid nanoparticles for oral administration: Pharmacodynamics and safety evaluation.

Guada M, Lana H, Gil AG, Dios-Viéitez Mdel C, Blanco-Prieto MJ.

Eur J Pharm Biopharm. 2016 Apr;101:112-8. doi: 10.1016/j.ejpb.2016.01.011. Epub 2016 Feb 10.

PMID:
26877154
24.

Reformulating cyclosporine A (CsA): More than just a life cycle management strategy.

Guada M, Beloqui A, Kumar MN, Préat V, Dios-Viéitez Mdel C, Blanco-Prieto MJ.

J Control Release. 2016 Mar 10;225:269-82. doi: 10.1016/j.jconrel.2016.01.056. Epub 2016 Jan 30. Review.

PMID:
26829101
25.

Lipid nanoparticles enhance the absorption of cyclosporine A through the gastrointestinal barrier: In vitro and in vivo studies.

Guada M, Lasa-Saracíbar B, Lana H, Dios-Viéitez Mdel C, Blanco-Prieto MJ.

Int J Pharm. 2016 Mar 16;500(1-2):154-61. doi: 10.1016/j.ijpharm.2016.01.037. Epub 2016 Jan 18.

PMID:
26794875
26.

Brain aging and Parkinson's disease: New therapeutic approaches using drug delivery systems.

Rodríguez-Nogales C, Garbayo E, Carmona-Abellán MM, Luquin MR, Blanco-Prieto MJ.

Maturitas. 2016 Feb;84:25-31. doi: 10.1016/j.maturitas.2015.11.009. Epub 2015 Nov 21. Review.

27.

A simple approach to obtain hybrid Au-loaded polymeric nanoparticles with a tunable metal load.

Luque-Michel E, Larrea A, Lahuerta C, Sebastian V, Imbuluzqueta E, Arruebo M, Blanco-Prieto MJ, Santamaría J.

Nanoscale. 2016 Mar 28;8(12):6495-506. doi: 10.1039/c5nr06850a.

28.

Tracking the in vivo release of bioactive NRG from PLGA and PEG-PLGA microparticles in infarcted hearts.

Pascual-Gil S, Simón-Yarza T, Garbayo E, Prosper F, Blanco-Prieto MJ.

J Control Release. 2015 Dec 28;220(Pt A):388-396. doi: 10.1016/j.jconrel.2015.10.058. Epub 2015 Nov 9.

PMID:
26546270
29.

Lipid nanoparticles for cyclosporine A administration: development, characterization, and in vitro evaluation of their immunosuppression activity.

Guada M, Sebastián V, Irusta S, Feijoó E, Dios-Viéitez Mdel C, Blanco-Prieto MJ.

Int J Nanomedicine. 2015 Oct 16;10:6541-53. doi: 10.2147/IJN.S90849. eCollection 2015.

30.

Antitumoral-Lipid-Based Nanoparticles: a Platform for Future Application in Osteosarcoma therapy.

González-Fernández Y, Imbuluzqueta E, Patiño-García A, Blanco-Prieto MJ.

Curr Pharm Des. 2015;21(42):6104-24. Review.

PMID:
26503148
31.

Lipid Nanosystems Enhance the Bioavailability and the Therapeutic Efficacy of FTY720 in Acute Myeloid Leukemia.

Estella-Hermoso de Mendoza A, Castello-Cros R, Imbuluzqueta E, Cirauqui C, Pippa R, Odero MD, Blanco-Prieto MJ.

J Biomed Nanotechnol. 2015 Apr;11(4):691-701.

PMID:
26310075
32.

Polymeric electrospun scaffolds: neuregulin encapsulation and biocompatibility studies in a model of myocardial ischemia.

Simón-Yarza T, Rossi A, Heffels KH, Prósper F, Groll J, Blanco-Prieto MJ.

Tissue Eng Part A. 2015 May;21(9-10):1654-61. doi: 10.1089/ten.TEA.2014.0523. Epub 2015 Mar 31.

33.

Heart regeneration after myocardial infarction using synthetic biomaterials.

Pascual-Gil S, Garbayo E, Díaz-Herráez P, Prosper F, Blanco-Prieto MJ.

J Control Release. 2015 Apr 10;203:23-38. doi: 10.1016/j.jconrel.2015.02.009. Epub 2015 Feb 7. Review.

PMID:
25665866
34.

Diagnostic and therapeutic uses of nanomaterials in the brain.

Garbayo E, Estella-Hermoso de Mendoza A, Blanco-Prieto MJ.

Curr Med Chem. 2014;21(36):4100-31. Review.

35.

Lipid nanoparticles protect from edelfosine toxicity in vivo.

Lasa-Saracíbar B, Aznar MÁ, Lana H, Aizpún I, Gil AG, Blanco-Prieto MJ.

Int J Pharm. 2014 Oct 20;474(1-2):1-5. doi: 10.1016/j.ijpharm.2014.07.053. Epub 2014 Aug 1.

PMID:
25091376
36.

Edelfosine lipid nanoparticles overcome multidrug resistance in K-562 leukemia cells by a caspase-independent mechanism.

Aznar MÁ, Lasa-Saracíbar B, Blanco-Prieto MJ.

Mol Pharm. 2014 Aug 4;11(8):2650-8. doi: 10.1021/mp5000696. Epub 2014 Jun 6.

37.

Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity.

Pippa R, Dominguez A, Christensen DJ, Moreno-Miralles I, Blanco-Prieto MJ, Vitek MP, Odero MD.

Leukemia. 2014 Sep;28(9):1915-8. doi: 10.1038/leu.2014.141. Epub 2014 Apr 30. No abstract available.

PMID:
24781014
38.

In vitro intestinal co-culture cell model to evaluate intestinal absorption of edelfosine lipid nanoparticles.

Lasa-Saracíbar B, Guada M, Sebastián V, Blanco-Prieto MJ.

Curr Top Med Chem. 2014;14(9):1124-32.

39.

Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration.

Formiga FR, Pelacho B, Garbayo E, Imbuluzqueta I, Díaz-Herráez P, Abizanda G, Gavira JJ, Simón-Yarza T, Albiasu E, Tamayo E, Prósper F, Blanco-Prieto MJ.

J Control Release. 2014 Jan 10;173:132-9. doi: 10.1016/j.jconrel.2013.10.034. Epub 2013 Nov 5.

40.

Adipose-derived stem cells combined with neuregulin-1 delivery systems for heart tissue engineering.

Díaz-Herráez P, Garbayo E, Simón-Yarza T, Formiga FR, Prosper F, Blanco-Prieto MJ.

Eur J Pharm Biopharm. 2013 Sep;85(1):143-50. doi: 10.1016/j.ejpb.2013.03.022.

41.

Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord.

des Rieux A, De Berdt P, Ansorena E, Ucakar B, Damien J, Schakman O, Audouard E, Bouzin C, Auhl D, Simón-Yarza T, Feron O, Blanco-Prieto MJ, Carmeliet P, Bailly C, Clotman F, Préat V.

J Biomed Mater Res A. 2014 Jul;102(7):2345-55. doi: 10.1002/jbm.a.34915. Epub 2013 Aug 30.

PMID:
23946111
42.

A simple and robust high-performance liquid chromatography coupled to a diode-array detector method for the analysis of genistein in mouse tissues.

Tamames-Tabar C, Imbuluzqueta E, Campanero MA, Horcajada P, Blanco-Prieto MJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 15;935:47-53. doi: 10.1016/j.jchromb.2013.07.020. Epub 2013 Jul 29.

43.

Injectable alginate hydrogel loaded with GDNF promotes functional recovery in a hemisection model of spinal cord injury.

Ansorena E, De Berdt P, Ucakar B, Simón-Yarza T, Jacobs D, Schakman O, Jankovski A, Deumens R, Blanco-Prieto MJ, Préat V, des Rieux A.

Int J Pharm. 2013 Oct 15;455(1-2):148-58. doi: 10.1016/j.ijpharm.2013.07.045. Epub 2013 Jul 31.

PMID:
23916821
44.

Drug development in Parkinson's disease: from emerging molecules to innovative drug delivery systems.

Garbayo E, Ansorena E, Blanco-Prieto MJ.

Maturitas. 2013 Nov;76(3):272-8. doi: 10.1016/j.maturitas.2013.05.019. Epub 2013 Jul 1. Review.

45.

Hydrophobic gentamicin-loaded nanoparticles are effective against Brucella melitensis infection in mice.

Imbuluzqueta E, Gamazo C, Lana H, Campanero MÁ, Salas D, Gil AG, Elizondo E, Ventosa N, Veciana J, Blanco-Prieto MJ.

Antimicrob Agents Chemother. 2013 Jul;57(7):3326-33. doi: 10.1128/AAC.00378-13. Epub 2013 May 6.

46.

Efficacy of edelfosine lipid nanoparticles in breast cancer cells.

Aznar MÁ, Lasa-Saracíbar B, Estella-Hermoso de Mendoza A, Blanco-Prieto MJ.

Int J Pharm. 2013 Oct 1;454(2):720-6. doi: 10.1016/j.ijpharm.2013.04.068. Epub 2013 Apr 30.

47.

Functional benefits of PLGA particulates carrying VEGF and CoQ10 in an animal of myocardial ischemia.

Simón-Yarza T, Tamayo E, Benavides C, Lana H, Formiga FR, Grama CN, Ortiz-de-Solorzano C, Kumar MN, Prosper F, Blanco-Prieto MJ.

Int J Pharm. 2013 Oct 1;454(2):784-90. doi: 10.1016/j.ijpharm.2013.04.015. Epub 2013 Apr 29.

48.

Nanotheraputics.

Ravi Kumar MN, Blanco-Prieto MJ, Waterhouse DN.

Cancer Lett. 2013 Jul 1;334(2):155-6. doi: 10.1016/j.canlet.2013.02.047. Epub 2013 Mar 21. No abstract available.

PMID:
23523611
49.

Biodegradation and heart retention of polymeric microparticles in a rat model of myocardial ischemia.

Formiga FR, Garbayo E, Díaz-Herráez P, Abizanda G, Simón-Yarza T, Tamayo E, Prósper F, Blanco-Prieto MJ.

Eur J Pharm Biopharm. 2013 Nov;85(3 Pt A):665-72. doi: 10.1016/j.ejpb.2013.02.017. Epub 2013 Mar 21.

50.

Ultra high performance liquid chromatography-tandem mass spectrometry method for cyclosporine a quantification in biological samples and lipid nanosystems.

Guada M, Imbuluzqueta E, Estella-Hermoso de Mendoza A, Lana H, Dios-Viéitez MC, Blanco-Prieto MJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 May 15;927:164-72. doi: 10.1016/j.jchromb.2013.02.001. Epub 2013 Feb 8.

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