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Items: 1 to 50 of 182

1.

Genetic determinants of VWF clearance and FVIII binding modify FVIII pharmacokinetics in pediatric hemophilia A patients.

Swystun LL, Ogiwara K, Rawley O, Brown C, Georgescu I, Hopman W, Labarque V, Male C, Thom K, Blanchette VS, Carcao MD, Lillicrap D.

Blood. 2019 Sep 12;134(11):880-891. doi: 10.1182/blood.2019000190. Epub 2019 Jul 26.

PMID:
31350267
2.

Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?

Carcao MD, Chelle P, Clarke E, Kim L, Tiseo L, Morfini M, Hossain T, Rand ML, Brown C, Edginton AN, Lillicrap D, Iorio A, Blanchette VS.

J Thromb Haemost. 2019 Jul;17(7):1085-1096. doi: 10.1111/jth.14469. Epub 2019 Jun 2.

PMID:
31038793
3.

Validation of the school age self-administered pediatric bleeding questionnaire (Self-PBQ) in children aged 8-12 years.

Bui J, Martyres D, James PD, Grabell J, Wu J, Steele M, Silva M, Rand ML, Blanchette VS, Barrowman N, Klaassen RJ.

Pediatr Blood Cancer. 2019 Jun;66(6):e27709. doi: 10.1002/pbc.27709. Epub 2019 Mar 22.

PMID:
30900820
4.

Long-term treatment with romiplostim and treatment-free platelet responses in children with chronic immune thrombocytopenia.

Tarantino MD, Bussel JB, Blanchette VS, Beam D, Roy J, Despotovic J, Raj A, Carpenter N, Mehta B, Eisen M.

Haematologica. 2019 Nov;104(11):2283-2291. doi: 10.3324/haematol.2018.202283. Epub 2019 Mar 7.

5.

Health-related quality of life in children with chronic immune thrombocytopenia treated with eltrombopag in the PETIT study.

Grainger JD, Blanchette VS, Grotzinger KM, Roy A, Bussel JB.

Br J Haematol. 2019 Apr;185(1):102-106. doi: 10.1111/bjh.15732. Epub 2018 Dec 27.

PMID:
30592022
6.

A Quality Improvement Bundle to Improve Informed Choice for Children With Typical, Newly Diagnosed Immune Thrombocytopenia.

Beck CE, Carcao M, Cada M, Porter S, Blanchette VS, Parkin PC.

J Pediatr Hematol Oncol. 2018 Nov;40(8):e537-e543. doi: 10.1097/MPH.0000000000001247.

PMID:
30028824
7.

The Jamaican Haemophilia Registry: Describing the burden of disease.

Wharfe G, Buchner-Daley L, Gibson T, Hilliard P, Usuba K, Abad A, Boma-Fischer L, Bouskill V, Floros G, Lillicrap D, Lowe Y, Lowe D, Palmer-Mitchell N, Rand ML, Teitel J, Tuttle A, Watson A, White R, Young NL, Blanchette VS.

Haemophilia. 2018 Jul;24(4):e179-e186. doi: 10.1111/hae.13517. Epub 2018 May 31.

PMID:
29855125
8.

Pharmacokinetic Studies of Factor VIII in Chinese Boys with Severe Hemophilia A: A Single-Center Study.

Chen ZP, Li PJ, Li G, Tang L, Zhen YZ, Wu XY, Cheng XL, Luke KH, Blanchette VS, Poon MC, Ding QL, Wu RH.

Chin Med J (Engl). 2018 Aug 5;131(15):1780-1785. doi: 10.4103/0366-6999.233604.

9.

Tailored frequency-escalated primary prophylaxis for severe haemophilia A: results of the 16-year Canadian Hemophilia Prophylaxis Study longitudinal cohort.

Feldman BM, Rivard GE, Babyn P, Wu JKM, Steele M, Poon MC, Card RT, Israels SJ, Laferriere N, Gill K, Chan AK, Carcao M, Klaassen RJ, Cloutier S, Price VE, Dover S, Blanchette VS.

Lancet Haematol. 2018 Jun;5(6):e252-e260. doi: 10.1016/S2352-3026(18)30048-6. Epub 2018 May 3.

PMID:
29731369
10.

Identifying Children with HEreditary Coagulation disorders (iCHEC): a protocol for a prospective cohort study.

Stokhuijzen E, Rand ML, Cnossen MH, Biss TT, James PD, Suijker MH, Peters M, van der Lee JH, Peters B, Meijer AB, Blanchette VS, Fijnvandraat K.

BMJ Open. 2018 May 3;8(5):e020686. doi: 10.1136/bmjopen-2017-020686.

11.

Severity and Features of Epistaxis in Children with a Mucocutaneous Bleeding Disorder.

Stokhuijzen E, Segbefia CI, Biss TT, Clark DS, James PD, Riddel J, Blanchette VS, Rand ML.

J Pediatr. 2018 Feb;193:183-189.e2. doi: 10.1016/j.jpeds.2017.09.082. Epub 2017 Dec 1.

PMID:
29198540
12.

Improved joint health in subjects with severe haemophilia A treated prophylactically with recombinant factor VIII Fc fusion protein.

Oldenburg J, Kulkarni R, Srivastava A, Mahlangu JN, Blanchette VS, Tsao E, Winding B, Dumont J, Jain N.

Haemophilia. 2018 Jan;24(1):77-84. doi: 10.1111/hae.13353. Epub 2017 Oct 30.

PMID:
29082639
13.

Development of a Thai version of the paediatric bleeding assessment tool (Thai paediatric-BAT) suitable for use in children with inherited mucocutaneous bleeding disorders.

Pakdeeto S, Natesirinilkul R, Komwilaisak P, Rand ML, Blanchette VS, Vallibhakara SA, Sirachainan N.

Haemophilia. 2017 Nov;23(6):e539-e542. doi: 10.1111/hae.13358. Epub 2017 Oct 10. No abstract available.

PMID:
28994494
14.

Describing the quality of life of boys with haemophilia in China: Results of a multicentre study using the CHO-KLAT.

Tang L, Xu W, Li CG, Hou F, Feng XQ, Wang H, Li XJ, Li WL, Liu JP, Sun LR, Wang SH, Jin J, Fang Q, Luke KH, Poon MC, Blanchette VS, Usuba K, Young NL, Wu R.

Haemophilia. 2018 Jan;24(1):113-119. doi: 10.1111/hae.13349. Epub 2017 Sep 18.

PMID:
28922525
15.

Imaging of haemophilic arthropathy in growing joints: pitfalls in ultrasound and MRI.

Soliman M, Daruge P, Dertkigil SSJ, De Avila Fernandes E, Negrao JR, de Aguiar Vilela Mitraud S, Sakuma ETI, Fernandes ARC, Zhang N, Huo A, Li YJ, Zhou F, Rodrigues BM, Mohanta A, Blanchette VS, Doria AS.

Haemophilia. 2017 Sep;23(5):660-672. doi: 10.1111/hae.13249. Epub 2017 Jun 2. Review.

PMID:
28574216
16.

Glanzmann thrombasthenia platelets compete with transfused platelets, reducing the haemostatic impact of platelet transfusions.

Al-Battat S, Rand ML, Bouskill V, Lau W, Blanchette VS, Kahr WHA, Rivard GE, Carcao MD.

Br J Haematol. 2018 May;181(3):410-413. doi: 10.1111/bjh.14623. Epub 2017 May 3. No abstract available.

PMID:
28466602
17.

Generation and optimization of the self-administered pediatric bleeding questionnaire and its validation as a screening tool for von Willebrand disease.

Casey LJ, Tuttle A, Grabell J, Hopman W, Moorehead PC, Blanchette VS, Wu JK, Steele M, Klaassen RJ, Silva M, Rand ML, James PD.

Pediatr Blood Cancer. 2017 Oct;64(10). doi: 10.1002/pbc.26588. Epub 2017 Apr 28.

PMID:
28453185
18.

An International Prophylaxis Study Group (IPSG) survey of prophylaxis in inhibitor positive children/adults with severe haemophilia.

Carcao MD, Avila L, Leissinger C, Blanchette VS, Aledort L; Factor Utilization Expert Working Group of the International Prophylaxis Study Group (IPSG) and Participating Survey Investigators.

Haemophilia. 2017 Sep;23(5):e444-e447. doi: 10.1111/hae.13222. Epub 2017 Apr 24. No abstract available.

PMID:
28439934
19.

A systematic review of ultrasound imaging as a tool for evaluating haemophilic arthropathy in children and adults.

Ligocki CC, Abadeh A, Wang KC, Adams-Webber T, Blanchette VS, Doria AS.

Haemophilia. 2017 Jul;23(4):598-612. doi: 10.1111/hae.13163. Epub 2017 Apr 21. Review.

PMID:
28429878
20.

An International Prophylaxis Study Group (IPSG) survey of prophylaxis in adults with severe haemophilia.

Carcao MD, Avila L, Leissinger C, Blanchette VS, Aledort L.

Haemophilia. 2017 Sep;23(5):e447-e450. doi: 10.1111/hae.13238. Epub 2017 Apr 21. No abstract available.

PMID:
28429874
21.

Insight into health-related quality of life of young children with haemophilia B treated with long-acting nonacog beta pegol recombinant factor IX.

Carcao M, Kearney S, Santagostino E, Oyesiku JOO, Young NL, Meunier J, Hoxer CS, Zhang C, Blanchette VS.

Haemophilia. 2017 May;23(3):e222-e224. doi: 10.1111/hae.13195. Epub 2017 Mar 30. No abstract available.

PMID:
28371032
22.

A prospective study of health-related quality of life of boys with severe haemophilia A in China: comparing on-demand to prophylaxis treatment.

Wu R, Sun J, Xiao J, Liu Y, Xue F, Wang H, Tang L, Zhao Y, Li K, Yang R, Hu Y, Luke KH, Poon MC, Blanchette VS, Usuba K, Young NL.

Haemophilia. 2017 May;23(3):430-436. doi: 10.1111/hae.13198. Epub 2017 Mar 27.

PMID:
28345299
23.

Utility of factor VIII and factor VIII to von Willebrand factor ratio in identifying 277 unselected carriers of hemophilia A.

Labarque V, Perinparajah V, Bouskill V, Stain AM, Wakefield C, Manuel C, Blanchette VS, James PD, Lillicrap D, Carcao MD.

Am J Hematol. 2017 Jun;92(6):E94-E96. doi: 10.1002/ajh.24709. Epub 2017 Apr 6. No abstract available.

24.

Decreased numbers of dense granules in fetal and neonatal platelets.

Urban D, Pluthero FG, Christensen H, Baidya S, Rand ML, Das A, Shah PS, Chitayat D, Blanchette VS, Kahr WH.

Haematologica. 2017 Feb;102(2):e36-e38. doi: 10.3324/haematol.2016.152421. Epub 2016 Nov 3. No abstract available.

25.

Validity of the Portuguese CHO-KLAT in Brazil.

Villaça PR, Blanchette VS, Carneiro JD, Ozelo MC, Antunes S, Feldman BM, Abad A, Usuba K, Young NL.

Haemophilia. 2016 Nov;22(6):894-897. doi: 10.1111/hae.13031. Epub 2016 Jul 25.

PMID:
27456858
26.

When and how to start prophylaxis in boys with severe hemophilia without inhibitors: communication from the SSC of the ISTH.

Fischer K, Collins PW, Ozelo MC, Srivastava A, Young G, Blanchette VS.

J Thromb Haemost. 2016 May;14(5):1105-9. doi: 10.1111/jth.13298. Epub 2016 Apr 4. Review. No abstract available.

27.

Romiplostim in children with immune thrombocytopenia: a phase 3, randomised, double-blind, placebo-controlled study.

Tarantino MD, Bussel JB, Blanchette VS, Despotovic J, Bennett C, Raj A, Williams B, Beam D, Morales J, Rose MJ, Carpenter N, Nie K, Eisen M.

Lancet. 2016 Jul 2;388(10039):45-54. doi: 10.1016/S0140-6736(16)00279-8. Epub 2016 Apr 18.

PMID:
27103127
28.

Reply to the letter of O'Mahoney et al.: Patient-reported outcome is not confined to HRQOL.

van den Berg HM, Feldman B, Fischer K, Blanchette VS, Poonnoose P, Srivastava A.

Haemophilia. 2016 May;22(3):e209-11. doi: 10.1111/hae.12933. Epub 2016 Apr 14. No abstract available.

PMID:
27076036
29.
30.

Association of peak factor VIII levels and area under the curve with bleeding in patients with haemophilia A on every third day pharmacokinetic-guided prophylaxis.

Valentino LA, Pipe SW, Collins PW, Blanchette VS, Berntorp E, Fischer K, Ewenstein BM, Oh M, Spotts G.

Haemophilia. 2016 Jul;22(4):514-20. doi: 10.1111/hae.12905. Epub 2016 Mar 1.

31.

Eltrombopag for the treatment of children with persistent and chronic immune thrombocytopenia (PETIT): a randomised, multicentre, placebo-controlled study.

Bussel JB, de Miguel PG, Despotovic JM, Grainger JD, Sevilla J, Blanchette VS, Krishnamurti L, Connor P, David M, Boayue KB, Matthews DC, Lambert MP, Marcello LM, Iyengar M, Chan GW, Chagin KD, Theodore D, Bailey CK, Bakshi KK.

Lancet Haematol. 2015 Aug;2(8):e315-25. doi: 10.1016/S2352-3026(15)00114-3. Epub 2015 Jul 28. Erratum in: Lancet Haematol. 2015 Oct;2(10):e407.

PMID:
26688484
32.

Definitions in hemophilia: resolved and unresolved issues.

Blanchette VS, Srivastava A.

Semin Thromb Hemost. 2015 Nov;41(8):819-25. doi: 10.1055/s-0035-1564800. Epub 2015 Oct 19. Review.

PMID:
26479892
33.

International cross-cultural validation study of the Canadian haemophilia outcomes: kids' life assessment tool.

McCusker PJ, Fischer K, Holzhauer S, Meunier S, Altisent C, Grainger JD, Blanchette VS, Burke TA, Wakefield C, Young NL.

Haemophilia. 2015 May;21(3):351-7. doi: 10.1111/hae.12597. Epub 2014 Dec 4.

PMID:
25471939
34.

A pilot randomized control trial to evaluate the feasibility of an Internet-based self-management and transitional care program for youth with haemophilia.

Breakey VR, Ignas DM, Warias AV, White M, Blanchette VS, Stinson JN.

Haemophilia. 2014 Nov;20(6):784-93. doi: 10.1111/hae.12488. Epub 2014 Oct 14.

PMID:
25311370
35.

Validation of the Chinese version of the Canadian Haemophilia Outcomes-Kids' Life Assessment Tool (the CHO-KLAT).

Wu R, Zhang J, Sun J, Zhou M, Wu JS, Li N, Li X, Luke KH, Poon MC, Blanchette VS, Young NL.

Haemophilia. 2014 Nov;20(6):794-9. doi: 10.1111/hae.12489. Epub 2014 Oct 2.

PMID:
25273150
36.

Definitions in hemophilia: communication from the SSC of the ISTH.

Blanchette VS, Key NS, Ljung LR, Manco-Johnson MJ, van den Berg HM, Srivastava A; Subcommittee on Factor VIII, Factor IX and Rare Coagulation Disorders of the Scientific and Standardization Committee of the International Society on Thrombosis and Hemostasis.

J Thromb Haemost. 2014 Nov;12(11):1935-9. doi: 10.1111/jth.12672. Epub 2014 Sep 3. No abstract available.

37.

Assessment of outcomes.

Blanchette VS, O'Mahony B, McJames L, Mahlangu JN.

Haemophilia. 2014 May;20 Suppl 4:114-20. doi: 10.1111/hae.12426. Review.

PMID:
24762286
38.

Shared decision making in the management of children with newly diagnosed immune thrombocytopenia.

Beck CE, Boydell KM, Stasiulis E, Blanchette VS, Llewellyn-Thomas H, Birken CS, Breakey VR, Parkin PC.

J Pediatr Hematol Oncol. 2014 Oct;36(7):559-65. doi: 10.1097/MPH.0000000000000120.

PMID:
24577546
39.

Phosphatidylserine exposure, microparticle formation and mitochondrial depolarisation in Glanzmann thrombasthenia platelets.

Wang H, Bang KW, Blanchette VS, Nurden AT, Rand ML.

Thromb Haemost. 2014 Jun;111(6):1184-6. doi: 10.1160/TH13-08-0704. Epub 2014 Jan 30. No abstract available.

PMID:
24477274
40.

Chinese Hemophilia Joint Health Score 2.1 reliability study.

Sun J, Hilliard PE, Feldman BM, Zourikian N, Chen L, Blanchette VS, Luke KH, Poon MC.

Haemophilia. 2014 May;20(3):435-40. doi: 10.1111/hae.12330. Epub 2013 Dec 16.

PMID:
24330460
41.

Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major.

Klaassen RJ, Barrowman N, Merelles-Pulcini M, Vichinsky EP, Sweeters N, Kirby-Allen M, Neufeld EJ, Kwiatkowski JL, Wu J, Vickars L, Blanchette VS, Forgie M, Yamashita R, Wong-Rieger D, Young NL.

Br J Haematol. 2014 Feb;164(3):431-7. doi: 10.1111/bjh.12631. Epub 2013 Nov 3.

PMID:
24180641
42.

The value of usability testing for Internet-based adolescent self-management interventions: "Managing Hemophilia Online".

Breakey VR, Warias AV, Ignas DM, White M, Blanchette VS, Stinson JN.

BMC Med Inform Decis Mak. 2013 Oct 4;13:113. doi: 10.1186/1472-6947-13-113.

43.

Quality of life in immune thrombocytopenia following treatment.

Grainger JD, Young NL, Blanchette VS, Klaassen RJ.

Arch Dis Child. 2013 Nov;98(11):895-7. doi: 10.1136/archdischild-2013-303784. Epub 2013 Aug 16.

PMID:
23956257
44.

Bleeding manifestations and management of children with persistent and chronic immune thrombocytopenia: data from the Intercontinental Cooperative ITP Study Group (ICIS).

Neunert CE, Buchanan GR, Imbach P, Bolton-Maggs PH, Bennett CM, Neufeld E, Vesely SK, Adix L, Blanchette VS, Kühne T; Intercontinental Cooperative ITP Study Group Registry II Participants.

Blood. 2013 May 30;121(22):4457-62. doi: 10.1182/blood-2012-12-466375. Epub 2013 Apr 2.

PMID:
23550040
45.

The genetics of Canadian type 3 von Willebrand disease: further evidence for co-dominant inheritance of mutant alleles.

Bowman M, Tuttle A, Notley C, Brown C, Tinlin S, Deforest M, Leggo J, Blanchette VS, Lillicrap D, James P; Association of Hemophilia Clinic Directors of Canada.

J Thromb Haemost. 2013 Mar;11(3):512-20. doi: 10.1111/jth.12130.

46.

An MRI scale for assessment of haemophilic arthropathy from the International Prophylaxis Study Group.

Lundin B, Manco-Johnson ML, Ignas DM, Moineddin R, Blanchette VS, Dunn AL, Gibikote SV, Keshava SN, Ljung R, Manco-Johnson MJ, Miller SF, Rivard GE, Doria AS; International Prophylaxis Study Group.

Haemophilia. 2012 Nov;18(6):962-70. doi: 10.1111/j.1365-2516.2012.02883.x. Epub 2012 Jul 5.

PMID:
22765835
47.

Childhood immune thrombocytopenia: a changing therapeutic landscape.

Breakey VR, Blanchette VS.

Semin Thromb Hemost. 2011 Oct;37(7):745-55. doi: 10.1055/s-0031-1297165. Epub 2011 Dec 20. Review.

PMID:
22187397
48.

Population pharmacokinetics of recombinant factor VIII: the relationships of pharmacokinetics to age and body weight.

Björkman S, Oh M, Spotts G, Schroth P, Fritsch S, Ewenstein BM, Casey K, Fischer K, Blanchette VS, Collins PW.

Blood. 2012 Jan 12;119(2):612-8. doi: 10.1182/blood-2011-07-360594. Epub 2011 Oct 31.

PMID:
22042695
49.

Exploring internet needs and use among adolescents with haemophilia: a website development project.

Sterling L, Nyhof-Young J, Blanchette VS, Breakey VR.

Haemophilia. 2012 Mar;18(2):216-21. doi: 10.1111/j.1365-2516.2011.02613.x. Epub 2011 Jul 29.

PMID:
21797947
50.

Joint health and functional ability in children with haemophilia who receive intensive replacement therapy.

Groen W, van der Net J, Bos K, Abad A, Bergstrom BM, Blanchette VS, Feldman BM, Funk S, Helders P, Hilliard P, Manco-Johnson M, Petrini P, Zourikian N, Fischer K.

Haemophilia. 2011 Sep;17(5):783-90. doi: 10.1111/j.1365-2516.2011.02606.x. Epub 2011 Jul 25.

PMID:
21790897

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