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Items: 36


Extent of MHC Clustering Regulates Selectivity and Effectiveness of T Cell Responses.

Anikeeva N, Fischer NO, Blanchette CD, Sykulev Y.

J Immunol. 2019 Jan 15;202(2):591-597. doi: 10.4049/jimmunol.1801196. Epub 2018 Dec 12.


Lipid composition dictates serum stability of reconstituted high-density lipoproteins: implications for in vivo applications.

Gilmore SF, Carpenter TS, Ingólfsson HI, Peters SKG, Henderson PT, Blanchette CD, Fischer NO.

Nanoscale. 2018 Apr 26;10(16):7420-7430. doi: 10.1039/C7NR09690A.


SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury.

Chang JC, Christiansen BA, Murugesh DK, Sebastian A, Hum NR, Collette NM, Hatsell S, Economides AN, Blanchette CD, Loots GG.

J Bone Miner Res. 2018 Jun;33(6):1105-1113. doi: 10.1002/jbmr.3397. Epub 2018 Apr 2.


Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development.

He W, Felderman M, Evans AC, Geng J, Homan D, Bourguet F, Fischer NO, Li Y, Lam KS, Noy A, Xing L, Cheng RH, Rasley A, Blanchette CD, Kamrud K, Wang N, Gouvis H, Peterson TC, Hubby B, Coleman MA.

J Biol Chem. 2017 Sep 8;292(36):15121-15132. doi: 10.1074/jbc.M117.784561. Epub 2017 Jul 24.


Enhancement of antigen-specific CD4+ and CD8+ T cell responses using a self-assembled biologic nanolipoprotein particle vaccine.

Weilhammer D, Dunkle AD, Blanchette CD, Fischer NO, Corzett M, Lehmann D, Boone T, Hoeprich P, Driks A, Rasley A.

Vaccine. 2017 Mar 13;35(11):1475-1481. doi: 10.1016/j.vaccine.2017.02.004. Epub 2017 Feb 14.


Lipid Cross-Linking of Nanolipoprotein Particles Substantially Enhances Serum Stability and Cellular Uptake.

Gilmore SF, Blanchette CD, Scharadin TM, Hura GL, Rasley A, Corzett M, Pan CX, Fischer NO, Henderson PT.

ACS Appl Mater Interfaces. 2016 Aug 17;8(32):20549-57. doi: 10.1021/acsami.6b04609. Epub 2016 Aug 4.


Printable enzyme-embedded materials for methane to methanol conversion.

Blanchette CD, Knipe JM, Stolaroff JK, DeOtte JR, Oakdale JS, Maiti A, Lenhardt JM, Sirajuddin S, Rosenzweig AC, Baker SE.

Nat Commun. 2016 Jun 15;7:11900. doi: 10.1038/ncomms11900.


Expression and Association of the Yersinia pestis Translocon Proteins, YopB and YopD, Are Facilitated by Nanolipoprotein Particles.

Coleman MA, Cappuccio JA, Blanchette CD, Gao T, Arroyo ES, Hinz AK, Bourguet FA, Segelke B, Hoeprich PD, Huser T, Laurence TA, Motin VL, Chromy BA.

PLoS One. 2016 Mar 25;11(3):e0150166. doi: 10.1371/journal.pone.0150166. eCollection 2016.


Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study.

Leroueil PR, DiMaggio S, Leistra AN, Blanchette CD, Orme C, Sinniah K, Orr BG, Banaszak Holl MM.

J Phys Chem B. 2015 Sep 3;119(35):11506-12. doi: 10.1021/acs.jpcb.5b05391. Epub 2015 Aug 14.


Evaluation of nanolipoprotein particles (NLPs) as an in vivo delivery platform.

Fischer NO, Weilhammer DR, Dunkle A, Thomas C, Hwang M, Corzett M, Lychak C, Mayer W, Urbin S, Collette N, Chiun Chang J, Loots GG, Rasley A, Blanchette CD.

PLoS One. 2014 Mar 27;9(3):e93342. doi: 10.1371/journal.pone.0093342. eCollection 2014.


The use of nanolipoprotein particles to enhance the immunostimulatory properties of innate immune agonists against lethal influenza challenge.

Weilhammer DR, Blanchette CD, Fischer NO, Alam S, Loots GG, Corzett M, Thomas C, Lychak C, Dunkle AD, Ruitenberg JJ, Ghanekar SA, Sant AJ, Rasley A.

Biomaterials. 2013 Dec;34(38):10305-18. doi: 10.1016/j.biomaterials.2013.09.038. Epub 2013 Sep 27.


Colocalized delivery of adjuvant and antigen using nanolipoprotein particles enhances the immune response to recombinant antigens.

Fischer NO, Rasley A, Corzett M, Hwang MH, Hoeprich PD, Blanchette CD.

J Am Chem Soc. 2013 Feb 13;135(6):2044-7. doi: 10.1021/ja3063293. Epub 2013 Jan 31.


Characterizing diffusion dynamics of a membrane protein associated with nanolipoproteins using fluorescence correlation spectroscopy.

Gao T, Blanchette CD, He W, Bourguet F, Ly S, Katzen F, Kudlicki WA, Henderson PT, Laurence TA, Huser T, Coleman MA.

Protein Sci. 2011 Feb;20(2):437-47. doi: 10.1002/pro.577.


Thermally induced phase separation in supported bilayers of glycosphingolipid and phospholipid mixtures.

Szmodis AW, Blanchette CD, Longo ML, Orme CA, Parikh AN.

Biointerphases. 2010 Dec;5(4):120-30. doi: 10.1116/1.3524295.


Isolation, characterization, and stability of discretely-sized nanolipoprotein particles assembled with apolipophorin-III.

Fischer NO, Blanchette CD, Segelke BW, Corzett M, Chromy BA, Kuhn EA, Bench G, Hoeprich PD.

PLoS One. 2010 Jul 19;5(7):e11643. doi: 10.1371/journal.pone.0011643.


Kinetic analysis of his-tagged protein binding to nickel-chelating nanolipoprotein particles.

Blanchette CD, Fischer NO, Corzett M, Bench G, Hoeprich PD.

Bioconjug Chem. 2010 Jul 21;21(7):1321-30. doi: 10.1021/bc100129s.


Conjugation to nickel-chelating nanolipoprotein particles increases the potency and efficacy of subunit vaccines to prevent West Nile encephalitis.

Fischer NO, Infante E, Ishikawa T, Blanchette CD, Bourne N, Hoeprich PD, Mason PW.

Bioconjug Chem. 2010 Jun 16;21(6):1018-22. doi: 10.1021/bc100083d.


Imaging cerebroside-rich domains for phase and shape characterization in binary and ternary mixtures.

Longo ML, Blanchette CD.

Biochim Biophys Acta. 2010 Jul;1798(7):1357-67. doi: 10.1016/j.bbamem.2009.11.013. Epub 2009 Nov 26. Review.


Characterization and purification of polydisperse reconstituted lipoproteins and nanolipoprotein particles.

Blanchette CD, Segelke BW, Fischer N, Corzett MH, Kuhn EA, Cappuccio JA, Benner WH, Coleman MA, Chromy BA, Bench G, Hoeprich PD, Sulchek TA.

Int J Mol Sci. 2009 Jul 2;10(7):2958-71. doi: 10.3390/ijms10072958.


Decoupling internalization, acidification and phagosomal-endosomal/lysosomal fusion during phagocytosis of InlA coated beads in epithelial cells.

Blanchette CD, Woo YH, Thomas C, Shen N, Sulchek TA, Hiddessen AL.

PLoS One. 2009 Jun 26;4(6):e6056. doi: 10.1371/journal.pone.0006056.


Hydrogen production by a hyperthermophilic membrane-bound hydrogenase in water-soluble nanolipoprotein particles.

Baker SE, Hopkins RC, Blanchette CD, Walsworth VL, Sumbad R, Fischer NO, Kuhn EA, Coleman M, Chromy BA, Létant SE, Hoeprich PD, Adams MW, Henderson PT.

J Am Chem Soc. 2009 Jun 10;131(22):7508-9. doi: 10.1021/ja809251f.


Immobilization of His-tagged proteins on nickel-chelating nanolipoprotein particles.

Fischer NO, Blanchette CD, Chromy BA, Kuhn EA, Segelke BW, Corzett M, Bench G, Mason PW, Hoeprich PD.

Bioconjug Chem. 2009 Mar 18;20(3):460-5. doi: 10.1021/bc8003155.


Atomic force microscopy differentiates discrete size distributions between membrane protein containing and empty nanolipoprotein particles.

Blanchette CD, Cappuccio JA, Kuhn EA, Segelke BW, Benner WH, Chromy BA, Coleman MA, Bench G, Hoeprich PD, Sulchek TA.

Biochim Biophys Acta. 2009 Mar;1788(3):724-31. doi: 10.1016/j.bbamem.2008.11.019. Epub 2008 Dec 8.


Cell-free expression for nanolipoprotein particles: building a high-throughput membrane protein solubility platform.

Cappuccio JA, Hinz AK, Kuhn EA, Fletcher JE, Arroyo ES, Henderson PT, Blanchette CD, Walsworth VL, Corzett MH, Law RJ, Pesavento JB, Segelke BW, Sulchek TA, Chromy BA, Katzen F, Peterson T, Bench G, Kudlicki W, Hoeprich PD Jr, Coleman MA.

Methods Mol Biol. 2009;498:273-96. doi: 10.1007/978-1-59745-196-3_18.


AFM for structure and dynamics of biomembranes.

Goksu EI, Vanegas JM, Blanchette CD, Lin WC, Longo ML.

Biochim Biophys Acta. 2009 Jan;1788(1):254-66. doi: 10.1016/j.bbamem.2008.08.021. Epub 2008 Sep 11. Review.


Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles.

Cappuccio JA, Blanchette CD, Sulchek TA, Arroyo ES, Kralj JM, Hinz AK, Kuhn EA, Chromy BA, Segelke BW, Rothschild KJ, Fletcher JE, Katzen F, Peterson TC, Kudlicki WA, Bench G, Hoeprich PD, Coleman MA.

Mol Cell Proteomics. 2008 Nov;7(11):2246-53. doi: 10.1074/mcp.M800191-MCP200. Epub 2008 Jul 4.


Insertion of membrane proteins into discoidal membranes using a cell-free protein expression approach.

Katzen F, Fletcher JE, Yang JP, Kang D, Peterson TC, Cappuccio JA, Blanchette CD, Sulchek T, Chromy BA, Hoeprich PD, Coleman MA, Kudlicki W.

J Proteome Res. 2008 Aug;7(8):3535-42. doi: 10.1021/pr800265f. Epub 2008 Jun 17.


Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations.

Blanchette CD, Law R, Benner WH, Pesavento JB, Cappuccio JA, Walsworth V, Kuhn EA, Corzett M, Chromy BA, Segelke BW, Coleman MA, Bench G, Hoeprich PD, Sulchek TA.

J Lipid Res. 2008 Jul;49(7):1420-30. doi: 10.1194/jlr.M700586-JLR200. Epub 2008 Apr 9.


Domain nucleation rates and interfacial line tensions in supported bilayers of ternary mixtures containing galactosylceramide.

Blanchette CD, Lin WC, Orme CA, Ratto TV, Longo ML.

Biophys J. 2008 Apr 1;94(7):2691-7. Epub 2007 Dec 7.


Quantifying growth of symmetric and asymmetric lipid bilayer domains.

Blanchette CD, Orme CA, Ratto TV, Longo ML.

Langmuir. 2008 Feb 19;24(4):1219-24. Epub 2007 Dec 7.


Different apolipoproteins impact nanolipoprotein particle formation.

Chromy BA, Arroyo E, Blanchette CD, Bench G, Benner H, Cappuccio JA, Coleman MA, Henderson PT, Hinz AK, Kuhn EA, Pesavento JB, Segelke BW, Sulchek TA, Tarasow T, Walsworth VL, Hoeprich PD.

J Am Chem Soc. 2007 Nov 21;129(46):14348-54. Epub 2007 Oct 27.


Lipid domains in supported lipid bilayer for atomic force microscopy.

Lin WC, Blanchette CD, Ratto TV, Longo ML.

Methods Mol Biol. 2007;400:503-13. Review.


Using nucleation rates to determine the interfacial line tension of symmetric and asymmetric lipid bilayer domains.

Blanchette CD, Lin WC, Orme CA, Ratto TV, Longo ML.

Langmuir. 2007 May 22;23(11):5875-7. Epub 2007 Apr 24.


Galactosylceramide domain microstructure: impact of cholesterol and nucleation/growth conditions.

Blanchette CD, Lin WC, Ratto TV, Longo ML.

Biophys J. 2006 Jun 15;90(12):4466-78. Epub 2006 Mar 24.


Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study.

Lin WC, Blanchette CD, Ratto TV, Longo ML.

Biophys J. 2006 Jan 1;90(1):228-37. Epub 2005 Oct 7.

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