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Items: 22


Distinct disruptions in Land's cycle remodeling of glycerophosphocholines in murine cortex mark symptomatic onset and progression in two Alzheimer's disease mouse models.

Granger MW, Liu H, Fowler CF, Blanchard AP, Taylor MW, Sherman SPM, Xu H, Le W, Bennett SAL.

J Neurochem. 2019 May;149(4):499-517. doi: 10.1111/jnc.14560. Epub 2018 Nov 8.


Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole.

Stresser DM, Perloff ES, Mason AK, Blanchard AP, Dehal SS, Creegan TP, Singh R, Gangl ET.

Drug Metab Dispos. 2016 Aug;44(8):1424-30. doi: 10.1124/dmd.116.070193. Epub 2016 May 5.


Platelet activating factors are associated with depressive symptoms in coronary artery disease patients: a hypothesis-generating study.

Mazereeuw G, Herrmann N, Xu H, Blanchard AP, Figeys D, Oh PI, Bennett SA, Lanctôt KL.

Neuropsychiatr Dis Treat. 2015 Sep 4;11:2309-14. doi: 10.2147/NDT.S87111. eCollection 2015.


Predicting glycerophosphoinositol identities in lipidomic datasets using VaLID (Visualization and Phospholipid Identification)--an online bioinformatic search engine.

McDowell GS, Blanchard AP, Taylor GP, Figeys D, Fai S, Bennett SA.

Biomed Res Int. 2014;2014:818670. doi: 10.1155/2014/818670. Epub 2014 Feb 20.


Phosphoproteome analysis of an early onset mouse model (TgCRND8) of Alzheimer's disease reveals temporal changes in neuronal and glia signaling pathways.

Wang F, Blanchard AP, Elisma F, Granger M, Xu H, Bennett SA, Figeys D, Zou H.

Proteomics. 2013 Apr;13(8):1292-305. doi: 10.1002/pmic.201200415. Epub 2013 Apr 2.


Visualization and Phospholipid Identification (VaLID): online integrated search engine capable of identifying and visualizing glycerophospholipids with given mass.

Blanchard AP, McDowell GS, Valenzuela N, Xu H, Gelbard S, Bertrand M, Slater GW, Figeys D, Fai S, Bennett SA.

Bioinformatics. 2013 Jan 15;29(2):284-5. doi: 10.1093/bioinformatics/bts662. Epub 2012 Nov 18.


Lipidomics era: accomplishments and challenges.

Bou Khalil M, Hou W, Zhou H, Elisma F, Swayne LA, Blanchard AP, Yao Z, Bennett SA, Figeys D.

Mass Spectrom Rev. 2010 Nov-Dec;29(6):877-929. doi: 10.1002/mas.20294. Review.


Polymorphism discovery in high-throughput resequenced microarray-enriched human genomic loci.

Antipova AA, Sokolsky TD, Clouser CR, Dimalanta ET, Hendrickson CL, Kosnopo C, Lee CC, Ranade SS, Zhang L, Blanchard AP, McKernan KJ.

J Biomol Tech. 2009 Dec;20(5):253-7.


Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism.

Ryan SD, Whitehead SN, Swayne LA, Moffat TC, Hou W, Ethier M, Bourgeois AJ, Rashidian J, Blanchard AP, Fraser PE, Park DS, Figeys D, Bennett SA.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20936-41. doi: 10.1073/pnas.0905654106. Epub 2009 Nov 19.


Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding.

McKernan KJ, Peckham HE, Costa GL, McLaughlin SF, Fu Y, Tsung EF, Clouser CR, Duncan C, Ichikawa JK, Lee CC, Zhang Z, Ranade SS, Dimalanta ET, Hyland FC, Sokolsky TD, Zhang L, Sheridan A, Fu H, Hendrickson CL, Li B, Kotler L, Stuart JR, Malek JA, Manning JM, Antipova AA, Perez DS, Moore MP, Hayashibara KC, Lyons MR, Beaudoin RE, Coleman BE, Laptewicz MW, Sannicandro AE, Rhodes MD, Gottimukkala RK, Yang S, Bafna V, Bashir A, MacBride A, Alkan C, Kidd JM, Eichler EE, Reese MG, De La Vega FM, Blanchard AP.

Genome Res. 2009 Sep;19(9):1527-41. doi: 10.1101/gr.091868.109. Epub 2009 Jun 22.


Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design.

Perloff ES, Mason AK, Dehal SS, Blanchard AP, Morgan L, Ho T, Dandeneau A, Crocker RM, Chandler CM, Boily N, Crespi CL, Stresser DM.

Xenobiotica. 2009 Feb;39(2):99-112. doi: 10.1080/00498250802638155.


Rapid whole-genome mutational profiling using next-generation sequencing technologies.

Smith DR, Quinlan AR, Peckham HE, Makowsky K, Tao W, Woolf B, Shen L, Donahue WF, Tusneem N, Stromberg MP, Stewart DA, Zhang L, Ranade SS, Warner JB, Lee CC, Coleman BE, Zhang Z, McLaughlin SF, Malek JA, Sorenson JM, Blanchard AP, Chapman J, Hillman D, Chen F, Rokhsar DS, McKernan KJ, Jeffries TW, Marth GT, Richardson PM.

Genome Res. 2008 Oct;18(10):1638-42. doi: 10.1101/gr.077776.108. Epub 2008 Sep 4.


Memantine potentiates agonist-induced Ca2+ responses in HEK 293 cells.

Blanchard AP, Guillemette G, Boulay G.

Cell Physiol Biochem. 2008;22(1-4):205-14. doi: 10.1159/000149798. Epub 2008 Jul 25.


Identification of two domains involved in the assembly of transient receptor potential canonical channels.

Lepage PK, Lussier MP, Barajas-Martinez H, Bousquet SM, Blanchard AP, Francoeur N, Dumaine R, Boulay G.

J Biol Chem. 2006 Oct 13;281(41):30356-64. Epub 2006 Aug 17.


Human cytochrome p450 induction and inhibition potential of clevidipine and its primary metabolite h152/81.

Zhang JG, Dehal SS, Ho T, Johnson J, Chandler C, Blanchard AP, Clark RJ Jr, Crespi CL, Stresser DM, Wong J.

Drug Metab Dispos. 2006 May;34(5):734-7. Epub 2006 Feb 24.


Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible.

Stresser DM, Broudy MI, Ho T, Cargill CE, Blanchard AP, Sharma R, Dandeneau AA, Goodwin JJ, Turner SD, Erve JC, Patten CJ, Dehal SS, Crespi CL.

Drug Metab Dispos. 2004 Jan;32(1):105-12.


Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4.

Stresser DM, Turner SD, Blanchard AP, Miller VP, Crespi CL.

Drug Metab Dispos. 2002 Jul;30(7):845-52.


Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer.

Hughes TR, Mao M, Jones AR, Burchard J, Marton MJ, Shannon KW, Lefkowitz SM, Ziman M, Schelter JM, Meyer MR, Kobayashi S, Davis C, Dai H, He YD, Stephaniants SB, Cavet G, Walker WL, West A, Coffey E, Shoemaker DD, Stoughton R, Blanchard AP, Friend SH, Linsley PS.

Nat Biotechnol. 2001 Apr;19(4):342-7.


Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates.

Stresser DM, Blanchard AP, Turner SD, Erve JC, Dandeneau AA, Miller VP, Crespi CL.

Drug Metab Dispos. 2000 Dec;28(12):1440-8.


Fluorometric high-throughput screening for inhibitors of cytochrome P450.

Miller VP, Stresser DM, Blanchard AP, Turner S, Crespi CL.

Ann N Y Acad Sci. 2000;919:26-32.


Cheap DNA arrays-it's not all smoke and mirrors.

Blanchard AP, Friend SH.

Nat Biotechnol. 1999 Oct;17(10):953. No abstract available. Erratum in: Nat Biotechnol 1999 Nov;17(11):1046.


Sequence to array: probing the genome's secrets.

Blanchard AP, Hood L.

Nat Biotechnol. 1996 Dec;14(13):1649. No abstract available.


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