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Targeted therapy in patients with PIK3CA-related overgrowth syndrome.

Venot Q, Blanc T, Rabia SH, Berteloot L, Ladraa S, Duong JP, Blanc E, Johnson SC, Hoguin C, Boccara O, Sarnacki S, Boddaert N, Pannier S, Martinez F, Magassa S, Yamaguchi J, Knebelmann B, Merville P, Grenier N, Joly D, Cormier-Daire V, Michot C, Bole-Feysot C, Picard A, Soupre V, Lyonnet S, Sadoine J, Slimani L, Chaussain C, Laroche-Raynaud C, Guibaud L, Broissand C, Amiel J, Legendre C, Terzi F, Canaud G.

Nature. 2018 Jun;558(7711):540-546. doi: 10.1038/s41586-018-0217-9. Epub 2018 Jun 13.


Prognostic value of early 18F-FDG PET scanning evaluation in immunocompetent primary CNS lymphoma patients.

Birsen R, Blanc E, Willems L, Burroni B, Legoff M, Le Ray E, Pilorge S, Salah S, Quentin A, Deau B, Franchi P, Vignon M, Mabille L, Nguyen C, Kirova Y, Varlet P, Edjlali M, Dezamis E, Hoang-Xuan K, Soussain C, Houillier C, Damotte D, Pallud J, Bouscary D, Tamburini J.

Oncotarget. 2018 Mar 30;9(24):16822-16831. doi: 10.18632/oncotarget.24706. eCollection 2018 Mar 30.


Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction.

Dobson AJ, He X, Blanc E, Bolukbasi E, Feseha Y, Yang M, Piper MDW.

NPJ Aging Mech Dis. 2018 Apr 17;4:5. doi: 10.1038/s41514-018-0024-4. eCollection 2018.


The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma.

Polena H, Creuzet J, Dufies M, Sidibé A, Khalil-Mgharbel A, Salomon A, Deroux A, Quesada JL, Roelants C, Filhol O, Cochet C, Blanc E, Ferlay-Segura C, Borchiellini D, Ferrero JM, Escudier B, Négrier S, Pages G, Vilgrain I.

Br J Cancer. 2018 May;118(9):1179-1188. doi: 10.1038/s41416-018-0054-5. Epub 2018 Mar 22.


Neurexin and Neuroligin-based adhesion complexes drive axonal arborisation growth independent of synaptic activity.

Constance WD, Mukherjee A, Fisher YE, Pop S, Blanc E, Toyama Y, Williams DW.

Elife. 2018 Mar 5;7. pii: e31659. doi: 10.7554/eLife.31659.


HEPATOFLUO: A prospective monocentric study assessing the benefits of indocyanine green (ICG) fluorescence for hepatic surgery.

Peyrat P, Blanc E, Guillermet S, Chen Y, Ferlay C, Perol D, Basso V, Rivoire M, Dupré A.

J Surg Oncol. 2018 Apr;117(5):922-927. doi: 10.1002/jso.25011. Epub 2018 Feb 23.


Efficacy and safety of high-dose etoposide cytarabine as consolidation following rituximab methotrexate temozolomide induction in newly diagnosed primary central nervous system lymphoma in immunocompetent patients.

Birsen R, Willems L, Pallud J, Blanc E, Burroni B, Legoff M, Le Ray E, Pilorge S, Deau B, Franchi P, Vignon M, Kirova Y, Edjlali M, Houillier C, Soussain C, Varlet P, Dezamis E, Damotte D, Bouscary D, Tamburini J.

Haematologica. 2018 Jul;103(7):e296-e299. doi: 10.3324/haematol.2017.185843. Epub 2018 Feb 22. No abstract available.


The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway.

Warnier M, Flaman JM, Chouabe C, Wiel C, Gras B, Griveau A, Blanc E, Foy JP, Mathot P, Saintigny P, Van Coppenolle F, Vindrieux D, Martin N, Bernard D.

Aging Cell. 2018 Jun;17(3):e12736. doi: 10.1111/acel.12736. Epub 2018 Feb 15.


Bibliometric analysis of a century of research on oral erythroplakia and leukoplakia.

Foy JP, Bertolus C, Goudot P, Deneuve S, Blanc E, Lasset C, Pérol D, Saintigny P.

J Oral Pathol Med. 2018 Apr;47(4):388-395. doi: 10.1111/jop.12683. Epub 2018 Feb 13.


Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.

Scholler P, Nevoltris D, de Bundel D, Bossi S, Moreno-Delgado D, Rovira X, Møller TC, El Moustaine D, Mathieu M, Blanc E, McLean H, Dupuis E, Mathis G, Trinquet E, Daniel H, Valjent E, Baty D, Chames P, Rondard P, Pin JP.

Nat Commun. 2017 Dec 6;8(1):1967. doi: 10.1038/s41467-017-01489-1.


Is current irrigation sustainable in the United States? An integrated assessment of climate change impact on water resources and irrigated crop yields.

Blanc E, Caron J, Fant C, Monier E.

Earths Future. 2017 Aug;5(8):877-892. doi: 10.1002/2016EF000473. Epub 2017 Aug 30.


Phase I dose-escalation study of pazopanib combined with bevacizumab in patients with metastatic renal cell carcinoma or other advanced tumors.

Négrier S, Pérol D, Bahleda R, Hollebecque A, Chatelut E, Boyle H, Cassier P, Metzger S, Blanc E, Soria JC, Escudier B.

BMC Cancer. 2017 Aug 15;17(1):547. doi: 10.1186/s12885-017-3527-7.


Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells.

Attignon EA, Distel E, Le-Grand B, Leblanc AF, Barouki R, de Oliveira E, Aggerbeck M, Blanc EB.

Toxicol In Vitro. 2017 Dec;45(Pt 3):309-317. doi: 10.1016/j.tiv.2017.06.029. Epub 2017 Jul 1.


Hypothyroidism in hospitalized elderly patients: a sign of worse prognosis.

Sforza N, Rosenfarb J, Rujelman R, Rosmarin M, Blanc E, Frigerio C, Fossati P, Caruso D, Faingold C, Meroño T, Brenta G.

J Endocrinol Invest. 2017 Dec;40(12):1303-1310. doi: 10.1007/s40618-017-0690-2. Epub 2017 May 22.


Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development.

Thomas-Jinu S, Gordon PM, Fielding T, Taylor R, Smith BN, Snowden V, Blanc E, Vance C, Topp S, Wong CH, Bielen H, Williams KL, McCann EP, Nicholson GA, Pan-Vazquez A, Fox AH, Bond CS, Talbot WS, Blair IP, Shaw CE, Houart C.

Neuron. 2017 May 17;94(4):931. doi: 10.1016/j.neuron.2017.04.036. No abstract available.


Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.

Aubert CE, Floriani C, Bauer DC, da Costa BR, Segna D, Blum MR, Collet TH, Fink HA, Cappola AR, Syrogiannouli L, Peeters RP, Åsvold BO, den Elzen WPJ, Luben RN, Bremner AP, Gogakos A, Eastell R, Kearney PM, Hoff M, Le Blanc E, Ceresini G, Rivadeneira F, Uitterlinden AG, Khaw KT, Langhammer A, Stott DJ, Westendorp RGJ, Ferrucci L, Williams GR, Gussekloo J, Walsh JP, Aujesky D, Rodondi N; Thyroid Studies Collaboration.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2719-2728. doi: 10.1210/jc.2017-00294.


Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan.

Piper MDW, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L.

Cell Metab. 2017 May 2;25(5):1206. doi: 10.1016/j.cmet.2017.04.020. No abstract available.


Hypercalcemia revealing diffuse granulomatous myositis.

Caré W, Blanc E, Cournac JM, Doutrelon C, Aletti M, Lecoules S.

Eur J Nucl Med Mol Imaging. 2017 Aug;44(8):1413-1414. doi: 10.1007/s00259-017-3693-5. Epub 2017 Apr 10. No abstract available.


Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development.

Thomas-Jinu S, Gordon PM, Fielding T, Taylor R, Smith BN, Snowden V, Blanc E, Vance C, Topp S, Wong CH, Bielen H, Williams KL, McCann EP, Nicholson GA, Pan-Vazquez A, Fox AH, Bond CS, Talbot WS, Blair IP, Shaw CE, Houart C.

Neuron. 2017 Apr 19;94(2):322-336.e5. doi: 10.1016/j.neuron.2017.03.026. Epub 2017 Apr 6.


Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan.

Piper MDW, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L.

Cell Metab. 2017 Mar 7;25(3):610-621. doi: 10.1016/j.cmet.2017.02.005. Erratum in: Cell Metab. 2017 May 2;25(5):1206.


Efficacy of high-intensity focused ultrasound-assisted hepatic resection (HIFU-AR) on blood loss reduction in patients with liver metastases requiring hepatectomy: study protocol for a randomized controlled trial.

Dupré A, Pérol D, Blanc E, Peyrat P, Basso V, Chen Y, Vincenot J, Kocot A, Melodelima D, Rivoire M.

Trials. 2017 Feb 6;18(1):57. doi: 10.1186/s13063-017-1801-2.


DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.

Mamlouk S, Childs LH, Aust D, Heim D, Melching F, Oliveira C, Wolf T, Durek P, Schumacher D, Bläker H, von Winterfeld M, Gastl B, Möhr K, Menne A, Zeugner S, Redmer T, Lenze D, Tierling S, Möbs M, Weichert W, Folprecht G, Blanc E, Beule D, Schäfer R, Morkel M, Klauschen F, Leser U, Sers C.

Nat Commun. 2017 Jan 25;8:14093. doi: 10.1038/ncomms14093.


Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy.

Moyle LA, Blanc E, Jaka O, Prueller J, Banerji CR, Tedesco FS, Harridge SD, Knight RD, Zammit PS.

Elife. 2016 Nov 14;5. pii: e11405. doi: 10.7554/eLife.11405.


FDG PET-CT for solitary pulmonary nodule and lung cancer: Literature review.

Groheux D, Quere G, Blanc E, Lemarignier C, Vercellino L, de Margerie-Mellon C, Merlet P, Querellou S.

Diagn Interv Imaging. 2016 Oct;97(10):1003-1017. doi: 10.1016/j.diii.2016.06.020. Epub 2016 Aug 24. Review.


Serum 25-hydroxyvitamin D level and incident type 2 diabetes in older men, the Osteoporotic Fractures in Men (MrOS) study.

Napoli N, Schafer AL, Lui LY, Cauley JA, Strotmeyer ES, Le Blanc ES, Hoffman AR, Lee CG, Black DM, Schwartz AV.

Bone. 2016 Sep;90:181-4. doi: 10.1016/j.bone.2016.07.001. Epub 2016 Jul 5.


Impact of Dyrk1A level on alcohol metabolism.

Renon M, Legrand B, Blanc E, Daubigney F, Bokobza C, Mortreux M, Paul JL, Delabar JM, Rouach H, Andreau K, Janel N.

Biochim Biophys Acta. 2016 Sep;1862(9):1495-503. doi: 10.1016/j.bbadis.2016.05.011. Epub 2016 May 20.


Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells.

Attignon EA, Leblanc AF, Le-Grand B, Duval C, Aggerbeck M, Rouach H, Blanc EB.

Arch Toxicol. 2017 Jan;91(1):313-324. doi: 10.1007/s00204-016-1700-4. Epub 2016 Apr 8.


Early Sitting in Ischemic Stroke Patients (SEVEL): A Randomized Controlled Trial.

Herisson F, Godard S, Volteau C, Le Blanc E, Guillon B, Gaudron M; SEVEL study group.

PLoS One. 2016 Mar 29;11(3):e0149466. doi: 10.1371/journal.pone.0149466. eCollection 2016.


Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling.

Santos CX, Hafstad AD, Beretta M, Zhang M, Molenaar C, Kopec J, Fotinou D, Murray TV, Cobb AM, Martin D, Zeh Silva M, Anilkumar N, Schröder K, Shanahan CM, Brewer AC, Brandes RP, Blanc E, Parsons M, Belousov V, Cammack R, Hider RC, Steiner RA, Shah AM.

EMBO J. 2016 Feb 1;35(3):319-34. doi: 10.15252/embj.201592394. Epub 2016 Jan 7.



Blanc E, Engblom S, Hellander A, Lötstedt P.

Multiscale Model Simul. 2016;14(2):668-707. doi: 10.1137/15M1013110. Epub 2016 May 3.


A serum metabolomic fingerprint of bevacizumab and temsirolimus combination as first-line treatment of metastatic renal cell carcinoma.

Jobard E, Blanc E, Négrier S, Escudier B, Gravis G, Chevreau C, Elena-Herrmann B, Trédan O.

Br J Cancer. 2015 Oct 20;113(8):1148-57. doi: 10.1038/bjc.2015.322. Epub 2015 Sep 15.


Design and validation of a homogeneous time-resolved fluorescence cell-based assay targeting the ligand-gated ion channel 5-HT3A.

Blanc E, Wagner P, Plaisier F, Schmitt M, Durroux T, Bourguignon JJ, Partiseti M, Dupuis E, Bihel F.

Anal Biochem. 2015 Sep 1;484:105-12. doi: 10.1016/j.ab.2015.03.035. Epub 2015 May 18.


Comment on "Acoustical observation of bubble oscillations induced by bubble popping".

Blanc É, Ollivier F, Antkowiak A, Wunenburger R.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Mar;91(3):036401. Epub 2015 Mar 24.


Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome.

Blanc E, Ponce C, Brodschi D, Nepote A, Barreto A, Schnitman M, Fossati P, Salgado P, Cejas C, Faingold C, Musso C, Brenta G.

Metab Syndr Relat Disord. 2015 Jun;13(5):221-6. doi: 10.1089/met.2014.0158. Epub 2015 Mar 19.


Estimating unbiased economies of scale of HIV prevention projects: a case study of Avahan.

Lépine A, Vassall A, Chandrashekar S, Blanc E, Le Nestour A.

Soc Sci Med. 2015 Apr;131:164-72. doi: 10.1016/j.socscimed.2015.03.007. Epub 2015 Mar 5.


Breast infiltration by relapsed acute lymphoblastic leukaemia on FDG PET/CT.

Luzurier A, Van Der Gucht A, Blanc E, Lengline E, Groheux D, Vercellino L, Merlet P.

Eur J Nucl Med Mol Imaging. 2015 Apr;42(5):811-2. doi: 10.1007/s00259-014-2977-2. Epub 2015 Jan 9. No abstract available.


Dissecting the role of Wnt signaling and its interactions with FGF signaling during midbrain neurogenesis.

Dyer C, Blanc E, Stanley RJ, Knight RD.

Neurogenesis (Austin). 2015 Sep 21;2(1):e1057313. doi: 10.1080/23262133.2015.1057313. eCollection 2015.


Pharmacokinetics of pazopanib administered in combination with bevacizumab.

Imbs DC, Négrier S, Cassier P, Hollebecque A, Varga A, Blanc E, Lafont T, Escudier B, Soria JC, Pérol D, Chatelut E.

Cancer Chemother Pharmacol. 2014 Jun;73(6):1189-96. doi: 10.1007/s00280-014-2455-3. Epub 2014 Apr 6.


An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology.

Fernandes de Abreu DA, Caballero A, Fardel P, Stroustrup N, Chen Z, Lee K, Keyes WD, Nash ZM, López-Moyado IF, Vaggi F, Cornils A, Regenass M, Neagu A, Ostojic I, Liu C, Cho Y, Sifoglu D, Shen Y, Fontana W, Lu H, Csikasz-Nagy A, Murphy CT, Antebi A, Blanc E, Apfeld J, Zhang Y, Alcedo J, Ch'ng Q.

PLoS Genet. 2014 Mar 27;10(3):e1004225. doi: 10.1371/journal.pgen.1004225. eCollection 2014 Mar.


Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.

Machado CB, Kanning KC, Kreis P, Stevenson D, Crossley M, Nowak M, Iacovino M, Kyba M, Chambers D, Blanc E, Lieberam I.

Development. 2014 Feb;141(4):784-94. doi: 10.1242/dev.097188. Erratum in: Development. 2014 Mar 15;141(6):1416.


(18)F-FDG PET/CT scan in malignant priapism with diffuse pulmonary adenocarcinoma metastatic invasion of both corpus spongiosum and cavernosum.

Blanc E, Calais J, Cardot V, Mabille L.

Eur J Nucl Med Mol Imaging. 2014 Mar;41(3):588-9. doi: 10.1007/s00259-013-2644-z. Epub 2013 Dec 18. No abstract available.


A time-domain numerical modeling of two-dimensional wave propagation in porous media with frequency-dependent dynamic permeability.

Blanc E, Chiavassa G, Lombard B.

J Acoust Soc Am. 2013 Dec;134(6):4610. doi: 10.1121/1.4824832.


A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain.

Dyer C, Blanc E, Hanisch A, Roehl H, Otto GW, Yu T, Basson MA, Knight R.

Development. 2014 Jan;141(1):63-72. doi: 10.1242/dev.099507. Epub 2013 Nov 27.


A phase II trial of sunitinib in patients with renal cell cancer and untreated brain metastases.

Chevreau C, Ravaud A, Escudier B, Amela E, Delva R, Rolland F, Tosi D, Oudard S, Blanc E, Ferlay C, Négrier S; French Group on Renal Cancer.

Clin Genitourin Cancer. 2014 Feb;12(1):50-4. doi: 10.1016/j.clgc.2013.09.008. Epub 2013 Sep 28.


A holidic medium for Drosophila melanogaster.

Piper MD, Blanc E, Leitão-Gonçalves R, Yang M, He X, Linford NJ, Hoddinott MP, Hopfen C, Soultoukis GA, Niemeyer C, Kerr F, Pletcher SD, Ribeiro C, Partridge L.

Nat Methods. 2014 Jan;11(1):100-5. doi: 10.1038/nmeth.2731. Epub 2013 Nov 17. Erratum in: Nat Methods. 2015 Nov;12(11):1098. Nat Methods. 2014 Sep;11(9):971.


Accuracy of magnetic resonance enterography in assessing response to therapy and mucosal healing in patients with Crohn's disease.

Ordás I, Rimola J, Rodríguez S, Paredes JM, Martínez-Pérez MJ, Blanc E, Arévalo JA, Aduna M, Andreu M, Radosevic A, Ramírez-Morros AM, Pinó S, Gallego M, Jauregui-Amezaga A, Ricart E, Panés J.

Gastroenterology. 2014 Feb;146(2):374-82.e1. doi: 10.1053/j.gastro.2013.10.055. Epub 2013 Oct 29.


Combination of lipid metabolism alterations and their sensitivity to inflammatory cytokines in human lipin-1-deficient myoblasts.

Michot C, Mamoune A, Vamecq J, Viou MT, Hsieh LS, Testet E, Lainé J, Hubert L, Dessein AF, Fontaine M, Ottolenghi C, Fouillen L, Nadra K, Blanc E, Bastin J, Candon S, Pende M, Munnich A, Smahi A, Djouadi F, Carman GM, Romero N, de Keyzer Y, de Lonlay P.

Biochim Biophys Acta. 2013 Dec;1832(12):2103-14. doi: 10.1016/j.bbadis.2013.07.021. Epub 2013 Aug 6.


Prognostic value of serum CA9 in patients with metastatic clear cell renal cell carcinoma under targeted therapy.

Gigante M, Li G, Ferlay C, Perol D, Blanc E, Paul S, Zhao A, Tostain J, Escudier B, Negrier S, Genin C.

Anticancer Res. 2012 Dec;32(12):5447-51.


Innate aminoglycoside resistance of Achromobacter xylosoxidans is due to AxyXY-OprZ, an RND-type multidrug efflux pump.

Bador J, Amoureux L, Blanc E, Neuwirth C.

Antimicrob Agents Chemother. 2013 Jan;57(1):603-5. doi: 10.1128/AAC.01243-12. Epub 2012 Oct 22.


Experimental investigation of MRgHIFU sonication with interleaved electronic and mechanical displacement of the focal point for transrectal prostate application.

Petrusca L, Ngo J, Brasset L, Blanc E, Murillo A, Auboiroux V, Cotton F, Chapelon JY, Salomir R.

Phys Med Biol. 2012 Aug 7;57(15):4805-25. doi: 10.1088/0031-9155/57/15/4805. Epub 2012 Jul 6.


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