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Items: 1 to 50 of 57

1.

Generation of Markerless Deletions in the Nosocomial Pathogen Clostridium difficile by Induction of DNA Double-Strand Breaks.

Theophilou ES, Vohra P, Gallagher MP, Poxton IR, Blakely GW.

Appl Environ Microbiol. 2019 Jan 23;85(3). pii: e02055-18. doi: 10.1128/AEM.02055-18. Print 2019 Feb 1.

2.

Antigenic mimicry of ubiquitin by the gut bacterium Bacteroides fragilis: a potential link with autoimmune disease.

Stewart L, D M Edgar J, Blakely G, Patrick S.

Clin Exp Immunol. 2018 Nov;194(2):153-165. doi: 10.1111/cei.13195. Epub 2018 Sep 17.

3.

Novel large-scale chromosomal transfer in Bacteroides fragilis contributes to its pan-genome and rapid environmental adaptation.

Husain F, Tang K, Veeranagouda Y, Boente R, Patrick S, Blakely G, Wexler HM.

Microb Genom. 2017 Nov;3(11). doi: 10.1099/mgen.0.000136.

4.

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices.

Venkateswaran S, Gwynne PJ, Wu M, Hardman A, Lilienkampf A, Pernagallo S, Blakely G, Swann DG, Bradley M, Gallagher MP.

J Vis Exp. 2016 Nov 5;(117). doi: 10.3791/54382.

5.

A single chromosome assembly of Bacteroides fragilis strain BE1 from Illumina and MinION nanopore sequencing data.

Risse J, Thomson M, Patrick S, Blakely G, Koutsovoulos G, Blaxter M, Watson M.

Gigascience. 2015 Dec 4;4:60. doi: 10.1186/s13742-015-0101-6. eCollection 2015.

7.

The Impact of Foreign Postings on Accompanying Military Spouses: An Ethnographic Study.

Blakely G, Hennessy C, Chung MC, Skirton H.

Health Psychol Res. 2014 Aug 26;2(2):1468. doi: 10.4081/hpr.2014.1468. eCollection 2014 Apr 26.

8.

Adaption and adjustment of military spouses to overseas postings: an online forum study.

Blakely G, Hennessy C, Chung MC, Skirton H.

Nurs Health Sci. 2014 Sep;16(3):387-94. doi: 10.1111/nhs.12122. Epub 2014 Mar 17.

PMID:
24636280
9.

Easing the global burden of diarrhoeal disease: can synthetic biology help?

Vohra P, Blakely GW.

Syst Synth Biol. 2013 Sep;7(3):73-8. doi: 10.1007/s11693-013-9114-6. Epub 2013 Jul 20.

10.

ArdA proteins from different mobile genetic elements can bind to the EcoKI Type I DNA methyltransferase of E. coli K12.

Chen K, Reuter M, Sanghvi B, Roberts GA, Cooper LP, Tilling M, Blakely GW, Dryden DT.

Biochim Biophys Acta. 2014 Mar;1844(3):505-11. doi: 10.1016/j.bbapap.2013.12.008. Epub 2013 Dec 22.

11.

Mutations of the domain forming the dimeric interface of the ArdA protein affect dimerization and antimodification activity but not antirestriction activity.

Roberts GA, Chen K, Bower EK, Madrzak J, Woods A, Barker AM, Cooper LP, White JH, Blakely GW, Manfield I, Dryden DT.

FEBS J. 2013 Oct;280(19):4903-14. doi: 10.1111/febs.12467. Epub 2013 Sep 2.

12.
13.

Removal of a frameshift between the hsdM and hsdS genes of the EcoKI Type IA DNA restriction and modification system produces a new type of system and links the different families of Type I systems.

Roberts GA, Chen K, Cooper LP, White JH, Blakely GW, Dryden DT.

Nucleic Acids Res. 2012 Nov;40(21):10916-24. doi: 10.1093/nar/gks876. Epub 2012 Sep 23.

14.

Exploring the DNA mimicry of the Ocr protein of phage T7.

Roberts GA, Stephanou AS, Kanwar N, Dawson A, Cooper LP, Chen K, Nutley M, Cooper A, Blakely GW, Dryden DT.

Nucleic Acids Res. 2012 Sep;40(16):8129-43. doi: 10.1093/nar/gks516. Epub 2012 Jun 7.

15.

A systematic review of the impact of foreign postings on accompanying spouses of military personnel.

Blakely G, Hennessy C, Chung MC, Skirton H.

Nurs Health Sci. 2012 Mar;14(1):121-32. doi: 10.1111/j.1442-2018.2011.00659.x. Epub 2012 Feb 3. Review.

PMID:
22303841
16.

A unique homologue of the eukaryotic protein-modifier ubiquitin present in the bacterium Bacteroides fragilis, a predominant resident of the human gastrointestinal tract.

Patrick S, Jobling KL, O'Connor D, Thacker Z, Dryden DT, Blakely GW.

Microbiology. 2011 Nov;157(Pt 11):3071-8. doi: 10.1099/mic.0.049940-0. Epub 2011 Sep 1.

17.

Multi-drug resistant Bacteroides fragilis recovered from blood and severe leg wounds caused by an improvised explosive device (IED) in Afghanistan.

Sherwood JE, Fraser S, Citron DM, Wexler H, Blakely G, Jobling K, Patrick S.

Anaerobe. 2011 Aug;17(4):152-5. doi: 10.1016/j.anaerobe.2011.02.007. Epub 2011 Mar 3.

PMID:
21376821
18.

Twenty-eight divergent polysaccharide loci specifying within- and amongst-strain capsule diversity in three strains of Bacteroides fragilis.

Patrick S, Blakely GW, Houston S, Moore J, Abratt VR, Bertalan M, Cerdeño-Tárraga AM, Quail MA, Corton N, Corton C, Bignell A, Barron A, Clark L, Bentley SD, Parkhill J.

Microbiology. 2010 Nov;156(Pt 11):3255-69. doi: 10.1099/mic.0.042978-0. Epub 2010 Sep 9.

19.

Improving emergency care pathways: an action research approach.

Endacott R, Cooper S, Sheaff R, Padmore J, Blakely G.

Emerg Med J. 2011 Mar;28(3):203-7. doi: 10.1136/emj.2009.082859. Epub 2010 Jun 26.

PMID:
20581383
20.

Use of educational games in the health professions: a mixed-methods study of educators' perspectives in the UK.

Blakely G, Skirton H, Cooper S, Allum P, Nelmes P.

Nurs Health Sci. 2010 Mar;12(1):27-32. doi: 10.1111/j.1442-2018.2009.00479.x.

PMID:
20487322
21.

Binding and degradation of fibrinogen by Bacteroides fragilis and characterization of a 54 kDa fibrinogen-binding protein.

Houston S, Blakely GW, McDowell A, Martin L, Patrick S.

Microbiology. 2010 Aug;156(Pt 8):2516-26. doi: 10.1099/mic.0.038588-0. Epub 2010 May 13.

PMID:
20466764
22.

Single-molecule imaging of Bacteroides fragilis AddAB reveals the highly processive translocation of a single motor helicase.

Reuter M, Parry F, Dryden DT, Blakely GW.

Nucleic Acids Res. 2010 Jun;38(11):3721-31. doi: 10.1093/nar/gkq100. Epub 2010 Feb 25.

23.

The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro.

Serfiotis-Mitsa D, Herbert AP, Roberts GA, Soares DC, White JH, Blakely GW, Uhrín D, Dryden DT.

Nucleic Acids Res. 2010 Mar;38(5):1723-37. doi: 10.1093/nar/gkp1144. Epub 2009 Dec 9.

24.

Learning through play.

Skirton H, Blakely G.

Nurs Stand. 2009 Oct 28-Nov 3;24(8):61. No abstract available.

PMID:
19911615
25.

Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance.

McMahon SA, Roberts GA, Johnson KA, Cooper LP, Liu H, White JH, Carter LG, Sanghvi B, Oke M, Walkinshaw MD, Blakely GW, Naismith JH, Dryden DT.

Nucleic Acids Res. 2009 Aug;37(15):4887-97. doi: 10.1093/nar/gkp478. Epub 2009 Jun 8.

26.

Changing the beat.

Blakely G.

Health Manag Technol. 2009 May;30(5):18-9, 25. No abstract available.

PMID:
19469157
27.

Protein folding in Escherichia coli: the chaperonin GroE and its substrates.

Masters M, Blakely G, Coulson A, McLennan N, Yerko V, Acord J.

Res Microbiol. 2009 May;160(4):267-77. doi: 10.1016/j.resmic.2009.04.002. Epub 2009 Apr 23.

PMID:
19393741
28.

Mutational analysis of genes implicated in LPS and capsular polysaccharide biosynthesis in the opportunistic pathogen Bacteroides fragilis.

Patrick S, Houston S, Thacker Z, Blakely GW.

Microbiology. 2009 Apr;155(Pt 4):1039-49. doi: 10.1099/mic.0.025361-0.

PMID:
19332806
29.

Educational gaming in the health sciences: systematic review.

Blakely G, Skirton H, Cooper S, Allum P, Nelmes P.

J Adv Nurs. 2009 Feb;65(2):259-69. doi: 10.1111/j.1365-2648.2008.04843.x. Epub 2008 Nov 14. Review.

PMID:
19032512
30.

The Orf18 gene product from conjugative transposon Tn916 is an ArdA antirestriction protein that inhibits type I DNA restriction-modification systems.

Serfiotis-Mitsa D, Roberts GA, Cooper LP, White JH, Nutley M, Cooper A, Blakely GW, Dryden DT.

J Mol Biol. 2008 Nov 28;383(5):970-81. doi: 10.1016/j.jmb.2008.06.005. Epub 2008 Jun 7.

PMID:
18838147
31.

Moral dilemmas associated with the withdrawal of artificial hydration.

Blakely G, Millward J.

Br J Nurs. 2007 Aug 9-Sep 12;16(15):916-9. Review.

PMID:
17851316
33.

Anabolic androgenic steroid affects social aggression and fear-related behaviors in male pair-housed rats.

Steensland P, Blakely G, Nyberg F, Fahlke C, Pohorecky LA.

Horm Behav. 2005 Aug;48(2):216-24.

PMID:
15878576
34.

Extensive DNA inversions in the B. fragilis genome control variable gene expression.

Cerdeño-Tárraga AM, Patrick S, Crossman LC, Blakely G, Abratt V, Lennard N, Poxton I, Duerden B, Harris B, Quail MA, Barron A, Clark L, Corton C, Doggett J, Holden MT, Larke N, Line A, Lord A, Norbertczak H, Ormond D, Price C, Rabbinowitsch E, Woodward J, Barrell B, Parkhill J.

Science. 2005 Mar 4;307(5714):1463-5.

35.

Smarter than the average phage.

Blakely GW.

Mol Microbiol. 2004 Nov;54(4):851-4.

36.

Is modification sufficient to protect a bacterial chromosome from a resident restriction endonuclease?

Makovets S, Powell LM, Titheradge AJ, Blakely GW, Murray NE.

Mol Microbiol. 2004 Jan;51(1):135-47.

37.

Coupling the initiation of chromosome replication to cell size in Escherichia coli.

Donachie WD, Blakely GW.

Curr Opin Microbiol. 2003 Apr;6(2):146-50. Review.

PMID:
12732304
38.

Multiple inverted DNA repeats of Bacteroides fragilis that control polysaccharide antigenic variation are similar to the hin region inverted repeats of Salmonella typhimurium.

Patrick S, Parkhill J, McCoy LJ, Lennard N, Larkin MJ, Collins M, Sczaniecka M, Blakely G.

Microbiology. 2003 Apr;149(Pt 4):915-24.

PMID:
12686634
39.

Growth phase variation in cell and nucleoid morphology in a Bacillus subtilis recA mutant.

Sciochetti SA, Blakely GW, Piggot PJ.

J Bacteriol. 2001 May;183(9):2963-8.

40.

Evolutionary divergence of an elongation factor 3 from Cryptococcus neoformans.

Blakely G, Hekman J, Chakraburtty K, Williamson PR.

J Bacteriol. 2001 Apr;183(7):2241-8.

41.

Identification and characterization of the dif Site from Bacillus subtilis.

Sciochetti SA, Piggot PJ, Blakely GW.

J Bacteriol. 2001 Feb;183(3):1058-68.

42.

Stability by multimer resolution of pJHCMW1 is due to the Tn1331 resolvase and not to the Escherichia coli Xer system.

Tolmasky ME, Colloms S, Blakely G, Sherratt DJ.

Microbiology. 2000 Mar;146 ( Pt 3):581-9.

PMID:
10746761
43.

Sequential strand exchange by XerC and XerD during site-specific recombination at dif.

Blakely GW, Davidson AO, Sherratt DJ.

J Biol Chem. 2000 Apr 7;275(14):9930-6.

44.

FtsK-dependent and -independent pathways of Xer site-specific recombination.

Recchia GD, Aroyo M, Wolf D, Blakely G, Sherratt DJ.

EMBO J. 1999 Oct 15;18(20):5724-34.

45.

The ripX locus of Bacillus subtilis encodes a site-specific recombinase involved in proper chromosome partitioning.

Sciochetti SA, Piggot PJ, Sherratt DJ, Blakely G.

J Bacteriol. 1999 Oct;181(19):6053-62.

46.

Site-specific recombination at dif by Haemophilus influenzae XerC.

Neilson L, Blakely G, Sherratt DJ.

Mol Microbiol. 1999 Feb;31(3):915-26.

47.

Binding and cleavage of nicked substrates by site-specific recombinases XerC and XerD.

Blakely GW, Davidson AO, Sherratt DJ.

J Mol Biol. 1997 Jan 10;265(1):30-9.

PMID:
8995522
48.

Cis and trans in site-specific recombination.

Blakely GW, Sherratt DJ.

Mol Microbiol. 1996 Apr;20(1):234-7. No abstract available.

PMID:
9091770
49.

Determinants of selectivity in Xer site-specific recombination.

Blakely G, Sherratt D.

Genes Dev. 1996 Mar 15;10(6):762-73.

50.

Site-specific recombination and circular chromosome segregation.

Sherratt DJ, Arciszewska LK, Blakely G, Colloms S, Grant K, Leslie N, McCulloch R.

Philos Trans R Soc Lond B Biol Sci. 1995 Jan 30;347(1319):37-42. Review.

PMID:
7746851

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