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Items: 27

1.

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.

Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, Ballet S, Liu ZJ, Müller CE, Stevens RC.

Sci Adv. 2019 Nov 27;5(11):eaax9115. doi: 10.1126/sciadv.aax9115. eCollection 2019 Nov.

2.

NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity.

Gharagozloo M, Mahmoud S, Simard C, Yamamoto K, Bobbala D, Ilangumaran S, Smith MD, Lamontagne A, Jarjoura S, Denault JB, Blais V, Gendron L, Vilariño-Güell C, Sadovnick AD, Ting JP, Calabresi PA, Amrani A, Gris D.

PLoS Biol. 2019 Sep 16;17(9):e3000451. doi: 10.1371/journal.pbio.3000451. eCollection 2019 Sep.

3.

The combination of opioid and neurotensin receptor agonists improves their analgesic/adverse effect ratio.

Eiselt E, Côté J, Longpré JM, Blais V, Sarret P, Gendron L.

Eur J Pharmacol. 2019 Apr 5;848:80-87. doi: 10.1016/j.ejphar.2019.01.048. Epub 2019 Jan 29.

PMID:
30707956
4.

N-Guanidyl and C-Tetrazole Leu-Enkephalin Derivatives: Efficient Mu and Delta Opioid Receptor Agonists with Improved Pharmacological Properties.

Beaudeau JL, Blais V, Holleran BJ, Bergeron A, Piñeyro G, Guérin B, Gendron L, Dory YL.

ACS Chem Neurosci. 2019 Mar 20;10(3):1615-1626. doi: 10.1021/acschemneuro.8b00550. Epub 2019 Jan 23.

PMID:
30614675
5.

Successful in vitro maturation of oocytes in a woman with gonadotropin-resistant ovary syndrome associated with a novel combination of FSH receptor gene variants: a case report.

Flageole C, Toufaily C, Bernard DJ, Ates S, Blais V, Chénier S, Benkhalifa M, Miron P.

J Assist Reprod Genet. 2019 Mar;36(3):425-432. doi: 10.1007/s10815-018-1394-z. Epub 2019 Jan 5.

PMID:
30610662
6.

Corrigendum to "Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings" [Bioorg. Med. Chem. Lett. 28(13) (2018) 2320-2323].

Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S.

Bioorg Med Chem Lett. 2018 Nov 1;28(20):3418. doi: 10.1016/j.bmcl.2018.08.023. Epub 2018 Sep 5. No abstract available.

PMID:
30195888
7.

Chemical space screening around Phe3 in opioid peptides: Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings.

Willemse T, Eiselt E, Hollanders K, Schepens W, van Vlijmen HWT, Chung NN, Blais V, Holleran B, Longpré JM, Schiller PW, Maes BUW, Sarret P, Gendron L, Ballet S.

Bioorg Med Chem Lett. 2018 Jul 15;28(13):2320-2323. doi: 10.1016/j.bmcl.2018.05.015. Epub 2018 May 12. Erratum in: Bioorg Med Chem Lett. 2018 Nov 1;28(20):3418.

8.

Adeno-associated virus 2/9 delivery of Cre recombinase in mouse primary afferents.

Abdallah K, Nadeau F, Bergeron F, Blouin S, Blais V, Bradbury KM, Lavoie CL, Parent JL, Gendron L.

Sci Rep. 2018 May 9;8(1):7321. doi: 10.1038/s41598-018-25626-y.

9.

Synthesis and Evaluation of a 64Cu-Conjugate, a Selective δ-Opioid Receptor Positron Emission Tomography Imaging Agent.

Pirisedigh A, Blais V, Ait-Mohand S, Abdallah K, Holleran BJ, Leduc R, Dory YL, Gendron L, Guérin B.

Org Lett. 2017 Apr 21;19(8):2018-2021. doi: 10.1021/acs.orglett.7b00575. Epub 2017 Apr 3.

PMID:
28368122
10.

Involvement of the coatomer protein complex I in the intracellular traffic of the delta opioid receptor.

St-Louis É, Degrandmaison J, Grastilleur S, Génier S, Blais V, Lavoie C, Parent JL, Gendron L.

Mol Cell Neurosci. 2017 Mar;79:53-63. doi: 10.1016/j.mcn.2016.12.005. Epub 2016 Dec 30.

11.

Synthesis of Gly-ψ[(Z)CF═CH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic.

Nadon JF, Rochon K, Grastilleur S, Langlois G, Dao TT, Blais V, Guérin B, Gendron L, Dory YL.

ACS Chem Neurosci. 2017 Jan 18;8(1):40-49. doi: 10.1021/acschemneuro.6b00163. Epub 2016 Nov 3.

PMID:
27762555
12.

Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis.

Elkoreh G, Blais V, Béliveau E, Guillemette G, Denault JB.

J Cell Biochem. 2012 Aug;113(8):2775-84. doi: 10.1002/jcb.24155.

PMID:
22473799
13.

Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis.

Boucher D, Blais V, Denault JB.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5669-74. doi: 10.1073/pnas.1200934109. Epub 2012 Mar 26.

14.

Molecular determinants involved in activation of caspase 7.

Boucher D, Blais V, Drag M, Denault JB.

Biosci Rep. 2011 Aug;31(4):283-94. doi: 10.1042/BSR20100111.

15.

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.

Oberst A, Pop C, Tremblay AG, Blais V, Denault JB, Salvesen GS, Green DR.

J Biol Chem. 2010 May 28;285(22):16632-42. doi: 10.1074/jbc.M109.095083. Epub 2010 Mar 22. Erratum in: J Biol Chem. 2014 Mar 7;289(10):6838.

16.

Characterization of a novel octopamine receptor expressed in the surf clam Spisula solidissima.

Blais V, Bounif N, Dubé F.

Gen Comp Endocrinol. 2010 Jun 1;167(2):215-27. doi: 10.1016/j.ygcen.2010.03.008. Epub 2010 Mar 17.

PMID:
20302871
17.

Sws1 is a conserved regulator of homologous recombination in eukaryotic cells.

Martín V, Chahwan C, Gao H, Blais V, Wohlschlegel J, Yates JR 3rd, McGowan CH, Russell P.

EMBO J. 2006 Jun 7;25(11):2564-74. Epub 2006 May 18.

18.

Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli.

Blais V, Turrin NP, Rivest S.

J Neurochem. 2005 Dec;95(6):1563-74. Epub 2005 Nov 8.

19.

BLM helicase facilitates Mus81 endonuclease activity in human cells.

Zhang R, Sengupta S, Yang Q, Linke SP, Yanaihara N, Bradsher J, Blais V, McGowan CH, Harris CC.

Cancer Res. 2005 Apr 1;65(7):2526-31.

20.
21.

RNA interference inhibition of Mus81 reduces mitotic recombination in human cells.

Blais V, Gao H, Elwell CA, Boddy MN, Gaillard PHL, Russell P, McGowan CH.

Mol Biol Cell. 2004 Feb;15(2):552-62. Epub 2003 Nov 14.

22.

[Role of the innate immune response in the brain].

Blais V, Rivest S.

Med Sci (Paris). 2003 Oct;19(10):981-7. Review. French.

24.

Processing of proendothelin-1 by members of the subtilisin-like pro-protein convertase family.

Blais V, Fugère M, Denault JB, Klarskov K, Day R, Leduc R.

FEBS Lett. 2002 Jul 31;524(1-3):43-8.

25.

Host immune response to Salmonella enterica serovar Typhimurium infection in mice derived from wild strains.

Sebastiani G, Blais V, Sancho V, Vogel SN, Stevenson MM, Gros P, Lapointe JM, Rivest S, Malo D.

Infect Immun. 2002 Apr;70(4):1997-2009.

27.

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