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Items: 1 to 50 of 367

1.

The proteome and its dynamics: A missing piece for integrative multi-omics in schizophrenia.

Borgmann-Winter KE, Wang K, Bandyopadhyay S, Torshizi AD, Blair IA, Hahn CG.

Schizophr Res. 2019 Aug 12. pii: S0920-9964(19)30303-2. doi: 10.1016/j.schres.2019.07.025. [Epub ahead of print]

PMID:
31416743
2.

Analytical Methods for Mass Spectrometry-Based Metabolomics Studies.

Wang S, Blair IA, Mesaros C.

Adv Exp Med Biol. 2019;1140:635-647. doi: 10.1007/978-3-030-15950-4_38.

PMID:
31347076
3.

The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting.

Blair IA, Farmer J, Hersch S, Larkindale J, Lynch DR, Napierala J, Napierala M, Payne RM, Subramony SH.

Future Sci OA. 2019 Jun 28;5(6):FSO398. doi: 10.2144/fsoa-2019-0026. Review.

4.

Evaluation of antibodies for western blot analysis of frataxin protein isoforms.

Weng L, Wang Q, Yu S, Yang X, Lynch DR, Mesaros C, Blair IA.

J Immunol Methods. 2019 Jul 4. pii: S0022-1759(19)30109-7. doi: 10.1016/j.jim.2019.07.001. [Epub ahead of print]

5.

Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells.

Lee SC, Shestov AA, Guo L, Zhang Q, Roman JC, Liu X, Wang HY, Pickup S, Nath K, Lu P, Hofbauer S, Mesaros C, Wang YL, Nelson DS, Schuster SJ, Blair IA, Glickson JD, Wasik MA.

Mol Cancer Res. 2019 Jun;17(6):1365-1377. doi: 10.1158/1541-7786.MCR-18-0256. Epub 2019 Mar 12.

PMID:
30862686
6.

Correction to Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia.

Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Rocha AG, Dancis A, Mesaros C, Lynch DR, Blair IA.

Anal Chem. 2019 Feb 5;91(3):2560. doi: 10.1021/acs.analchem.9b00141. Epub 2019 Jan 24. No abstract available.

PMID:
30676739
7.

Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia.

Lynch DR, Farmer J, Hauser L, Blair IA, Wang QQ, Mesaros C, Snyder N, Boesch S, Chin M, Delatycki MB, Giunti P, Goldsberry A, Hoyle C, McBride MG, Nachbauer W, O'Grady M, Perlman S, Subramony SH, Wilmot GR, Zesiewicz T, Meyer C.

Ann Clin Transl Neurol. 2018 Nov 10;6(1):15-26. doi: 10.1002/acn3.660. eCollection 2019 Jan.

8.

Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes.

Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Mesaros C, Lynch DR, Blair IA.

Sci Rep. 2018 Nov 19;8(1):17043. doi: 10.1038/s41598-018-35346-y.

9.

Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone.

Murray JR, Mesaros CA, Arlt VM, Seidel A, Blair IA, Penning TM.

Chem Res Toxicol. 2018 Nov 19;31(11):1277-1288. doi: 10.1021/acs.chemrestox.8b00250. Epub 2018 Nov 8.

PMID:
30406992
10.

Impact of route of administration on genotoxic oestrogens concentrations using oral vs transdermal oestradiol in girls with Turner syndrome.

Mauras N, Torres-Santiago L, Santen R, Mericq V, Ross J, Colon-Otero G, Damaso L, Hossain J, Wang Q, Mesaros C, Blair IA.

Clin Endocrinol (Oxf). 2019 Jan;90(1):155-161. doi: 10.1111/cen.13869. Epub 2018 Oct 25.

PMID:
30281805
11.

Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin.

Nath K, Roman J, Nelson DS, Guo L, Lee SC, Orlovskiy S, Muriuki K, Heitjan DF, Pickup S, Leeper DB, Blair IA, Putt ME, Glickson JD.

Sci Rep. 2018 Oct 2;8(1):14654. doi: 10.1038/s41598-018-33019-4.

12.

Gestational Diabetes Alters the Metabolomic Profile in 2nd Trimester Amniotic Fluid in a Sex-Specific Manner.

O'Neill K, Alexander J, Azuma R, Xiao R, Snyder NW, Mesaros CA, Blair IA, Pinney SE.

Int J Mol Sci. 2018 Sep 10;19(9). pii: E2696. doi: 10.3390/ijms19092696.

13.

Quantification of Serum High Mobility Group Box 1 by Liquid Chromatography/High-Resolution Mass Spectrometry: Implications for Its Role in Immunity, Inflammation, and Cancer.

Weng L, Guo L, Vachani A, Mesaros C, Blair IA.

Anal Chem. 2018 Jun 19;90(12):7552-7560. doi: 10.1021/acs.analchem.8b01175. Epub 2018 Jun 5.

14.

Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.

Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, Blair IA, Nissim I, Keith B, Simon MC.

Cell Metab. 2018 Jun 5;27(6):1263-1280.e6. doi: 10.1016/j.cmet.2018.04.009. Epub 2018 May 10.

15.

Bioorthogonal pro-metabolites for profiling short chain fatty acylation.

Sinclair WR, Shrimp JH, Zengeya TT, Kulkarni RA, Garlick JM, Luecke H, Worth AJ, Blair IA, Snyder NW, Meier JL.

Chem Sci. 2017 Dec 8;9(5):1236-1241. doi: 10.1039/c7sc00247e. eCollection 2018 Feb 7.

16.

The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations.

O'Connor RS, Guo L, Ghassemi S, Snyder NW, Worth AJ, Weng L, Kam Y, Philipson B, Trefely S, Nunez-Cruz S, Blair IA, June CH, Milone MC.

Sci Rep. 2018 Apr 19;8(1):6289. doi: 10.1038/s41598-018-24676-6.

17.

Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments.

Ecker C, Guo L, Voicu S, Gil-de-Gómez L, Medvec A, Cortina L, Pajda J, Andolina M, Torres-Castillo M, Donato JL, Mansour S, Zynda ER, Lin PY, Varela-Rohena A, Blair IA, Riley JL.

Cell Rep. 2018 Apr 17;23(3):741-755. doi: 10.1016/j.celrep.2018.03.084.

18.

Microbes vs. chemistry in the origin of the anaerobic gut lumen.

Friedman ES, Bittinger K, Esipova TV, Hou L, Chau L, Jiang J, Mesaros C, Lund PJ, Liang X, FitzGerald GA, Goulian M, Lee D, Garcia BA, Blair IA, Vinogradov SA, Wu GD.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4170-4175. doi: 10.1073/pnas.1718635115. Epub 2018 Apr 2.

19.

Effect of a tissue selective estrogen complex on breast cancer: Role of unique properties of conjugated equine estrogen.

Yue W, Wang J, Atkins KA, Bottalico L, Mesaros C, Blair IA, Santen RJ.

Int J Cancer. 2018 Sep 1;143(5):1259-1268. doi: 10.1002/ijc.31401. Epub 2018 Apr 16.

20.

Low apolipoprotein A-I levels in Friedreich's ataxia and in frataxin-deficient cells: Implications for therapy.

Wang Q, Guo L, Strawser CJ, Hauser LA, Hwang WT, Snyder NW, Lynch DR, Mesaros C, Blair IA.

PLoS One. 2018 Feb 15;13(2):e0192779. doi: 10.1371/journal.pone.0192779. eCollection 2018.

21.

Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS.

Mazaleuskaya LL, Salamatipour A, Sarantopoulou D, Weng L, FitzGerald GA, Blair IA, Mesaros C.

J Lipid Res. 2018 Mar;59(3):564-575. doi: 10.1194/jlr.D081414. Epub 2018 Jan 4.

22.

Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich's Ataxia.

Guo L, Wang Q, Weng L, Hauser LA, Strawser CJ, Rocha AG, Dancis A, Mesaros C, Lynch DR, Blair IA.

Anal Chem. 2018 Feb 6;90(3):2216-2223. doi: 10.1021/acs.analchem.7b04590. Epub 2018 Jan 11. Erratum in: Anal Chem. 2019 Feb 5;91(3):2560.

23.

Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes.

Shrimp JH, Garlick JM, Tezil T, Sorum AW, Worth AJ, Blair IA, Verdin E, Snyder NW, Meier JL.

Mol Pharm. 2018 Mar 5;15(3):729-736. doi: 10.1021/acs.molpharmaceut.7b00943. Epub 2017 Dec 29.

24.

Associations between improvement in genitourinary symptoms of menopause and changes in the vaginal ecosystem.

Mitchell CM, Srinivasan S, Plantinga A, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN.

Menopause. 2018 May;25(5):500-507. doi: 10.1097/GME.0000000000001037.

25.

On meta- and mega-analyses for gene-environment interactions.

Huang J, Liu Y, Vitale S, Penning TM, Whitehead AS, Blair IA, Vachani A, Clapper ML, Muscat JE, Lazarus P, Scheet P, Moore JH, Chen Y.

Genet Epidemiol. 2017 Dec;41(8):876-886. doi: 10.1002/gepi.22085. Epub 2017 Nov 7.

26.

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.

Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, Bae YK, Wulfkuhle JD, Gallagher RI, Petricoin EF Rd, Norris B, Flory CM, Schumacher RJ, O'Sullivan MG, Cao Q, Chu H, Lipscomb JD, Atkins WM, Gupta K, Kelekar A, Blair IA, Capdevila JH, Falck JR, Sligar SG, Poulos TL, Georg GI, Ambrose E, Potter DA.

Cell Chem Biol. 2017 Oct 19;24(10):1314. doi: 10.1016/j.chembiol.2017.09.012. No abstract available.

27.

Potential Metabolic Activation of Representative Alkylated Polycyclic Aromatic Hydrocarbons 1-Methylphenanthrene and 9-Ethylphenanthrene Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells.

Huang M, Mesaros C, Hackfeld LC, Hodge RP, Blair IA, Penning TM.

Chem Res Toxicol. 2017 Dec 18;30(12):2140-2150. doi: 10.1021/acs.chemrestox.7b00232. Epub 2017 Oct 27.

28.

Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases.

McAllister K, Mechanic LE, Amos C, Aschard H, Blair IA, Chatterjee N, Conti D, Gauderman WJ, Hsu L, Hutter CM, Jankowska MM, Kerr J, Kraft P, Montgomery SB, Mukherjee B, Papanicolaou GJ, Patel CJ, Ritchie MD, Ritz BR, Thomas DC, Wei P, Witte JS.

Am J Epidemiol. 2017 Oct 1;186(7):753-761. doi: 10.1093/aje/kwx227.

29.

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.

Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, Bae YK, Wulfkuhle JD, Gallagher RI, Petricoin EF Rd, Norris B, Flory CM, Schumacher RJ, O'Sullivan MG, Cao Q, Chu H, Lipscomb JD, Atkins WM, Gupta K, Kelekar A, Blair IA, Capdevila JH, Falck JR, Sligar SG, Poulos TL, Georg GI, Ambrose E, Potter DA.

Cell Chem Biol. 2017 Oct 19;24(10):1259-1275.e6. doi: 10.1016/j.chembiol.2017.08.009. Epub 2017 Sep 14. Erratum in: Cell Chem Biol. 2017 Oct 19;24(10):1314.

30.

Metabolic tracing analysis reveals substrate-specific metabolic deficits in platelet storage lesion.

Sims C, Salliant N, Worth AJ, Parry R, Mesaros C, Blair IA, Snyder NW.

Transfusion. 2017 Nov;57(11):2683-2689. doi: 10.1111/trf.14292. Epub 2017 Aug 23.

31.

Adrenocortical carcinoma and succinate dehydrogenase gene mutations: an observational case series.

Else T, Lerario AM, Everett J, Haymon L, Wham D, Mullane M, Wilson TL, Rainville I, Rana H, Worth AJ, Snyder NW, Blair IA, McKay R, Kilbridge K, Hammer G, Barletta J, Vaidya A.

Eur J Endocrinol. 2017 Nov;177(5):439-444. doi: 10.1530/EJE-17-0358. Epub 2017 Aug 17.

PMID:
28819017
32.

Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies.

Patel CJ, Kerr J, Thomas DC, Mukherjee B, Ritz B, Chatterjee N, Jankowska M, Madan J, Karagas MR, McAllister KA, Mechanic LE, Fallin MD, Ladd-Acosta C, Blair IA, Teitelbaum SL, Amos CI.

Cancer Epidemiol Biomarkers Prev. 2017 Sep;26(9):1370-1380. doi: 10.1158/1055-9965.EPI-17-0459. Epub 2017 Jul 14. Review.

33.

Testicular vs adrenal sources of hydroxy-androgens in prostate cancer.

Zang T, Taplin ME, Tamae D, Xie W, Mesaros C, Zhang Z, Bubley G, Montgomery B, Balk SP, Mostaghel EA, Blair IA, Penning TM.

Endocr Relat Cancer. 2017 Aug;24(8):393-404. doi: 10.1530/ERC-17-0107. Epub 2017 Jun 29.

34.

Vaginal microbiota and genitourinary menopausal symptoms: a cross-sectional analysis.

Mitchell CM, Srinivasan S, Zhan X, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN.

Menopause. 2017 Oct;24(10):1160-1166. doi: 10.1097/GME.0000000000000904.

35.

Comparison of statistical methods for detection of serum lipid biomarkers for mesothelioma and asbestos exposure.

Xu R, Mesaros C, Weng L, Snyder NW, Vachani A, Blair IA, Hwang WT.

Biomark Med. 2017 Jul;11(7):547-556. doi: 10.2217/bmm-2017-0087. Epub 2017 May 23.

36.

Biomarkers of exposure to new and emerging tobacco delivery products.

Schick SF, Blount BC, Jacob P Rd, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L425-L452. doi: 10.1152/ajplung.00343.2016. Epub 2017 May 18. Review.

37.

Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.

Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn WJ 3rd, Kopinski PK, Wang L, Akimova T, Liu Y, Bhatti TR, Han R, Laskin BL, Baur JA, Blair IA, Wallace DC, Hancock WW, Beier UH.

Cell Metab. 2017 Jun 6;25(6):1282-1293.e7. doi: 10.1016/j.cmet.2016.12.018. Epub 2017 Apr 13.

38.

Potential Metabolic Activation of a Representative C4-Alkylated Polycyclic Aromatic Hydrocarbon Retene (1-Methyl-7-isopropyl-phenanthrene) Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells.

Huang M, Mesaros C, Hackfeld LC, Hodge RP, Zang T, Blair IA, Penning TM.

Chem Res Toxicol. 2017 Apr 17;30(4):1093-1101. doi: 10.1021/acs.chemrestox.6b00457. Epub 2017 Mar 22.

39.

Coenzyme A thioester formation of 11- and 15-oxo-eicosatetraenoic acid.

Mesaros C, Arroyo AD, Blair IA, Snyder NW.

Prostaglandins Other Lipid Mediat. 2017 May;130:1-7. doi: 10.1016/j.prostaglandins.2017.02.004. Epub 2017 Feb 24.

40.

Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

Kulkarni RA, Worth AJ, Zengeya TT, Shrimp JH, Garlick JM, Roberts AM, Montgomery DC, Sourbier C, Gibbs BK, Mesaros C, Tsai YC, Das S, Chan KC, Zhou M, Andresson T, Weissman AM, Linehan WM, Blair IA, Snyder NW, Meier JL.

Cell Chem Biol. 2017 Feb 16;24(2):231-242. doi: 10.1016/j.chembiol.2017.01.002. Epub 2017 Feb 2.

41.

Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels.

Carrer A, Parris JL, Trefely S, Henry RA, Montgomery DC, Torres A, Viola JM, Kuo YM, Blair IA, Meier JL, Andrews AJ, Snyder NW, Wellen KE.

J Biol Chem. 2017 Feb 24;292(8):3312-3322. doi: 10.1074/jbc.M116.750620. Epub 2017 Jan 11.

42.

Company profile: BluePen Biomarkers LLC – integrated biomarker solutions.

Blair IA, Mesaros C, Lilley P, Nunez M.

Future Sci OA. 2016 Jun 9;2(2):FSO124. doi: 10.4155/fsoa-2016-0031. eCollection 2016 Jun. Erratum in: Future Sci OA. 2019 Jun 5;5(5):FSO408.

43.

A dynamic career in MS: applications to biomedical research.

Blair IA.

Future Sci OA. 2015 Nov 1;1(4):FSO52. doi: 10.4155/fso.15.52. eCollection 2015 Nov.

44.

Pretreatment Red Blood Cell Total Folate Concentration Is Associated With Response to Pemetrexed in Stage IV Nonsquamous Non-Small-cell Lung Cancer.

Bagley SJ, Vitale S, Zhang S, Aggarwal C, Evans TL, Alley EW, Cohen RB, Langer CJ, Blair IA, Vachani A, Whitehead AS.

Clin Lung Cancer. 2017 Mar;18(2):e143-e149. doi: 10.1016/j.cllc.2016.10.010. Epub 2016 Oct 26.

45.

Second trimester amniotic fluid bisphenol A concentration is associated with decreased birth weight in term infants.

Pinney SE, Mesaros CA, Snyder NW, Busch CM, Xiao R, Aijaz S, Ijaz N, Blair IA, Manson JM.

Reprod Toxicol. 2017 Jan;67:1-9. doi: 10.1016/j.reprotox.2016.11.007. Epub 2016 Nov 6.

46.

Mechanism of antineoplastic activity of lonidamine.

Nath K, Guo L, Nancolas B, Nelson DS, Shestov AA, Lee SC, Roman J, Zhou R, Leeper DB, Halestrap AP, Blair IA, Glickson JD.

Biochim Biophys Acta. 2016 Dec;1866(2):151-162. doi: 10.1016/j.bbcan.2016.08.001. Epub 2016 Aug 4. Review.

47.

Validation of highly sensitive simultaneous targeted and untargeted analysis of keto-steroids by Girard P derivatization and stable isotope dilution-liquid chromatography-high resolution mass spectrometry.

Frey AJ, Wang Q, Busch C, Feldman D, Bottalico L, Mesaros CA, Blair IA, Vachani A, Snyder NW.

Steroids. 2016 Dec;116:60-66. doi: 10.1016/j.steroids.2016.10.003. Epub 2016 Oct 13.

48.

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.

Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, Metallo CM, Snyder NW, Andrews AJ, Wellen KE.

Cell Rep. 2016 Oct 18;17(4):1037-1052. doi: 10.1016/j.celrep.2016.09.069.

49.

Mass spectrometry-based approaches to targeted quantitative proteomics in cardiovascular disease.

Mesaros C, Blair IA.

Clin Proteomics. 2016 Oct 5;13:20. eCollection 2016. Review.

50.

A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood.

Mazaleuskaya LL, Lawson JA, Li X, Grant G, Mesaros C, Grosser T, Blair IA, Ricciotti E, FitzGerald GA.

JCI Insight. 2016 Aug 4;1(12). pii: e87031.

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