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Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness.

Nwogu N, Boyne JR, Dobson SJ, Poterlowicz K, Blair GE, Macdonald A, Mankouri J, Whitehouse A.

PLoS Pathog. 2018 Sep 6;14(9):e1007276. doi: 10.1371/journal.ppat.1007276. eCollection 2018 Sep.


The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility.

Stakaitytė G, Nwogu N, Lippiat JD, Blair GE, Poterlowicz K, Boyne JR, Macdonald A, Mankouri J, Whitehouse A.

J Biol Chem. 2018 Mar 23;293(12):4582-4590. doi: 10.1074/jbc.RA117.001343. Epub 2018 Feb 8.


Blood Coagulation Factor X Exerts Differential Effects on Adenovirus Entry into Human Lymphocytes.

Findlay JS, Cook GP, Blair GE.

Viruses. 2018 Jan 3;10(1). pii: E20. doi: 10.3390/v10010020.


Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation.

Stakaitytė G, Nwogu N, Dobson SJ, Knight LM, Wasson CW, Salguero FJ, Blackbourn DJ, Blair GE, Mankouri J, Macdonald A, Whitehouse A.

J Virol. 2018 Jan 2;92(2). pii: e00940-17. doi: 10.1128/JVI.00940-17. Print 2018 Jan 15.


The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Enhances E1A Functional Activity.

Dallaire F, Schreiner S, Blair GE, Dobner T, Branton PE, Blanchette P.

mSphere. 2015 Nov 11;1(1). pii: e00015-15. doi: 10.1128/mSphere.00015-15. eCollection 2016 Jan-Feb.


The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F.

Dallaire F, Schreiner S, Blair GE, Dobner T, Branton PE, Blanchette P.

mSphere. 2015 Nov 11;1(1). pii: e00014-15. doi: 10.1128/mSphere.00014-15. eCollection 2016 Jan-Feb.


Corrigendum: NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma.

Wilson CL, Jurk D, Fullard N, Banks P, Page A, Luli S, Elsharkawy AM, Gieling RG, Bagchi Chakraborty J, Fox C, Richardson C, Callaghan K, Blair GE, Fox N, Lagnado A, Passos JF, Moore AJ, Smith GR, Tiniakos DG, Mann J, Oakley F, Mann DA.

Nat Commun. 2015 Sep 21;6:8411. doi: 10.1038/ncomms9411. No abstract available.


The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA Aptamers.

Cesur Ö, Nicol C, Groves H, Mankouri J, Blair GE, Stonehouse NJ.

Viruses. 2015 Jun 26;7(7):3443-61. doi: 10.3390/v7072780.


NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma.

Wilson CL, Jurk D, Fullard N, Banks P, Page A, Luli S, Elsharkawy AM, Gieling RG, Chakraborty JB, Fox C, Richardson C, Callaghan K, Blair GE, Fox N, Lagnado A, Passos JF, Moore AJ, Smith GR, Tiniakos DG, Mann J, Oakley F, Mann DA.

Nat Commun. 2015 Apr 16;6:6818. doi: 10.1038/ncomms7818. Erratum in: Nat Commun. 2015;6:8411.


Merkel cell polyomavirus small T antigen mediates microtubule destabilization to promote cell motility and migration.

Knight LM, Stakaityte G, Wood JJ, Abdul-Sada H, Griffiths DA, Howell GJ, Wheat R, Blair GE, Steven NM, Macdonald A, Blackbourn DJ, Whitehouse A.

J Virol. 2015 Jan;89(1):35-47. doi: 10.1128/JVI.02317-14. Epub 2014 Oct 15.


CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells.

Orchard-Webb DJ, Lee TC, Cook GP, Blair GE.

BMC Cancer. 2014 Oct 9;14:754. doi: 10.1186/1471-2407-14-754.


An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein.

Belyaeva TA, Nicol C, Cesur O, Travé G, Blair GE, Stonehouse NJ.

Cancers (Basel). 2014 Jul 24;6(3):1553-69. doi: 10.3390/cancers6031553.


Human papillomavirus E7 oncoprotein increases production of the anti-inflammatory interleukin-18 binding protein in keratinocytes.

Richards KH, Doble R, Wasson CW, Haider M, Blair GE, Wittmann M, Macdonald A.

J Virol. 2014 Apr;88(8):4173-9. doi: 10.1128/JVI.02546-13. Epub 2014 Jan 29.


Blocking oncogenic RAS enhances tumour cell surface MHC class I expression but does not alter susceptibility to cytotoxic lymphocytes.

El-Jawhari JJ, El-Sherbiny YM, Scott GB, Morgan RS, Prestwich R, Bowles PA, Blair GE, Tanaka T, Rabbitts TH, Meade JL, Cook GP.

Mol Immunol. 2014 Apr;58(2):160-8. doi: 10.1016/j.molimm.2013.11.020. Epub 2013 Dec 22.


Merkel cell polyomavirus small T antigen targets the NEMO adaptor protein to disrupt inflammatory signaling.

Griffiths DA, Abdul-Sada H, Knight LM, Jackson BR, Richards K, Prescott EL, Peach AH, Blair GE, Macdonald A, Whitehouse A.

J Virol. 2013 Dec;87(24):13853-67. doi: 10.1128/JVI.02159-13. Epub 2013 Oct 9.


An RNA aptamer provides a novel approach for the induction of apoptosis by targeting the HPV16 E7 oncoprotein.

Nicol C, Cesur Ö, Forrest S, Belyaeva TA, Bunka DH, Blair GE, Stonehouse NJ.

PLoS One. 2013 May 30;8(5):e64781. doi: 10.1371/journal.pone.0064781. Print 2013.


High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors.

Wetherill LF, Holmes KK, Verow M, Müller M, Howell G, Harris M, Fishwick C, Stonehouse N, Foster R, Blair GE, Griffin S, Macdonald A.

J Virol. 2012 May;86(9):5341-51. doi: 10.1128/JVI.06243-11. Epub 2012 Feb 22.


Impact of human adenovirus type 3 dodecahedron on host cells and its potential role in viral infection.

Fender P, Hall K, Schoehn G, Blair GE.

J Virol. 2012 May;86(9):5380-5. doi: 10.1128/JVI.07127-11. Epub 2012 Feb 15.


Novel impedimetric immunosensor for the detection and quantitation of Adenovirus using reduced antibody fragments immobilized onto a conducting copolymer surface.

Caygill RL, Hodges CS, Holmes JL, Higson SP, Blair GE, Millner PA.

Biosens Bioelectron. 2012 Feb 15;32(1):104-10. doi: 10.1016/j.bios.2011.11.041. Epub 2011 Dec 3.


The roles of cell surface attachment molecules and coagulation Factor X in adenovirus 5-mediated gene transfer in pancreatic cancer cells.

Hamdan S, Verbeke CS, Fox N, Booth J, Bottley G, Pandha HS, Blair GE.

Cancer Gene Ther. 2011 Jul;18(7):478-88. doi: 10.1038/cgt.2011.17. Epub 2011 May 13.


Effects of single nucleotide changes on the binding and activity of RNA aptamers to human papillomavirus 16 E7 oncoprotein.

Nicol C, Bunka DH, Blair GE, Stonehouse NJ.

Biochem Biophys Res Commun. 2011 Feb 18;405(3):417-21. doi: 10.1016/j.bbrc.2011.01.044. Epub 2011 Jan 14.


A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells.

Holmes TD, El-Sherbiny YM, Davison A, Clough SL, Blair GE, Cook GP.

J Immunol. 2011 Feb 1;186(3):1538-45. doi: 10.4049/jimmunol.1000951. Epub 2010 Dec 29.


A review on viral biosensors to detect human pathogens.

Caygill RL, Blair GE, Millner PA.

Anal Chim Acta. 2010 Nov 29;681(1-2):8-15. doi: 10.1016/j.aca.2010.09.038. Epub 2010 Oct 1. Review.


Unity and diversity in the human adenoviruses: exploiting alternative entry pathways for gene therapy.

Hall K, Blair Zajdel ME, Blair GE.

Biochem J. 2010 Nov 1;431(3):321-36. doi: 10.1042/BJ20100766. Review.


Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing.

Scott GB, Bowles PA, Wilson EB, Meade JL, Low BC, Davison A, Blair GE, Cook GP.

Biochem J. 2010 Nov 1;431(3):423-31. doi: 10.1042/BJ20091073.


The role of Cajal bodies in the expression of late phase adenovirus proteins.

James NJ, Howell GJ, Walker JH, Blair GE.

Virology. 2010 Apr 10;399(2):299-311. doi: 10.1016/j.virol.2010.01.013. Epub 2010 Feb 4.


Defining the role of CD46, CD80 and CD86 in mediating adenovirus type 3 fiber interactions with host cells.

Hall K, Blair Zajdel ME, Blair GE.

Virology. 2009 Sep 30;392(2):222-9. doi: 10.1016/j.virol.2009.07.010. Epub 2009 Aug 13.


Identification of genes differentially expressed as result of adenovirus type 5- and adenovirus type 12-transformation.

Strath J, Georgopoulos LJ, Kellam P, Blair GE.

BMC Genomics. 2009 Feb 6;10:67. doi: 10.1186/1471-2164-10-67.


Cancer and the immune system: an overview.

Blair GE, Cook GP.

Oncogene. 2008 Oct 6;27(45):5868. doi: 10.1038/onc.2008.277. No abstract available.


Analysis of pancreas tissue in a child positive for islet cell antibodies.

Oikarinen M, Tauriainen S, Honkanen T, Vuori K, Karhunen P, Vasama-Nolvi C, Oikarinen S, Verbeke C, Blair GE, Rantala I, Ilonen J, Simell O, Knip M, Hyöty H.

Diabetologia. 2008 Oct;51(10):1796-802. doi: 10.1007/s00125-008-1107-8. Epub 2008 Aug 12.


Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis.

Franqueville L, Henning P, Magnusson M, Vigne E, Schoehn G, Blair-Zajdel ME, Habib N, Lindholm L, Blair GE, Hong SS, Boulanger P.

PLoS One. 2008 Aug 6;3(8):e2894. doi: 10.1371/journal.pone.0002894.


High-risk human papillomavirus E7 expression reduces cell-surface MHC class I molecules and increases susceptibility to natural killer cells.

Bottley G, Watherston OG, Hiew YL, Norrild B, Cook GP, Blair GE.

Oncogene. 2008 Mar 13;27(12):1794-9. Epub 2007 Sep 10.


Flow cytometric detection of adenoviruses and intracellular adenovirus proteins.

Bottley G, Holt JR, James NJ, Blair GE.

Methods Mol Med. 2007;130:205-13.


Adsorption of DNA onto positively charged amidine colloidal spheres and the resultant bridging interaction.

Hodrien AJ, Waigh TA, Voice AM, Blair GE, Clarke SM.

Int J Biol Macromol. 2007 Jul 1;41(2):146-53. Epub 2007 Jan 30.


Expression of the CUB domain containing protein 1 (CDCP1) gene in colorectal tumour cells.

Perry SE, Robinson P, Melcher A, Quirke P, Bühring HJ, Cook GP, Blair GE.

FEBS Lett. 2007 Mar 20;581(6):1137-42. Epub 2007 Feb 20.


Adenovirus subversion of immune surveillance, apoptotic and growth regulatory pathways: a model for tumorigenesis.

Strath J, Blair GE.

Acta Microbiol Immunol Hung. 2006 Jun;53(2):145-69. Review.


Novel molecular approaches to cystic fibrosis gene therapy.

Lee TW, Matthews DA, Blair GE.

Biochem J. 2005 Apr 1;387(Pt 1):1-15. Review.


Precursor of human adenovirus core polypeptide Mu targets the nucleolus and modulates the expression of E2 proteins.

Lee TW, Lawrence FJ, Dauksaite V, Akusjärvi G, Blair GE, Matthews DA.

J Gen Virol. 2004 Jan;85(Pt 1):185-96.


Evasion of the immune system by adenoviruses.

Blair GE, Blair-Zajdel ME.

Curr Top Microbiol Immunol. 2004;273:3-28. Review.


Identification and characterisation of a cDNA encoding a 17-kDa isoform of rat myelin basic protein.

Matheus L, Blair GE.

Biochim Biophys Acta. 2003 Oct 20;1630(1):47-53.


Coxsackie B and adenovirus receptor, integrin and major histocompatibility complex class I expression in human prostate cancer cell lines: implications for gene therapy strategies.

Pandha HS, Stockwin LH, Eaton J, Clarke IA, Dalgleish AG, Todryk SM, Blair GE.

Prostate Cancer Prostatic Dis. 2003;6(1):6-11. Erratum in: Prostate Cancer Prostatic Dis. 2003;6(2):198.


Engineered expression of the Coxsackie B and adenovirus receptor (CAR) in human dendritic cells enhances recombinant adenovirus-mediated gene transfer.

Stockwin LH, Matzow T, Georgopoulos NT, Stanbridge LJ, Jones SV, Martin IG, Blair-Zajdel ME, Blair GE.

J Immunol Methods. 2002 Jan 1;259(1-2):205-15.


The specificity of the myelin basic protein gene promoter studied in transgenic mice.

Asipu A, Mellor AL, Blair GE.

Biochem Biophys Res Commun. 2001 Nov 9;288(4):809-18.


Dendritic cells: immunological sentinels with a central role in health and disease.

Stockwin LH, McGonagle D, Martin IG, Blair GE.

Immunol Cell Biol. 2000 Apr;78(2):91-102. Review.


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