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Items: 24

1.

Macrophage Inhibitory Factor-1 (MIF-1) controls the plasticity of multiple myeloma tumor cells.

Joseph D, Gonsky JP, Blain SW.

PLoS One. 2018 Nov 1;13(11):e0206368. doi: 10.1371/journal.pone.0206368. eCollection 2018.

2.

Targeting p27 tyrosine phosphorylation as a modality to inhibit CDK4 and CDK2 and cause cell cycle arrest in breast cancer cells.

Blain SW.

Oncoscience. 2018 Jun 25;5(5-6):144-145. doi: 10.18632/oncoscience.427. eCollection 2018 May. No abstract available.

3.

Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells.

Patel P, Tsiperson V, Gottesman SRS, Somma J, Blain SW.

Mol Cancer Res. 2018 Mar;16(3):361-377. doi: 10.1158/1541-7786.MCR-17-0602. Epub 2018 Jan 12.

PMID:
29330290
4.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

5.

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets.

Feitelson MA, Arzumanyan A, Kulathinal RJ, Blain SW, Holcombe RF, Mahajna J, Marino M, Martinez-Chantar ML, Nawroth R, Sanchez-Garcia I, Sharma D, Saxena NK, Singh N, Vlachostergios PJ, Guo S, Honoki K, Fujii H, Georgakilas AG, Bilsland A, Amedei A, Niccolai E, Amin A, Ashraf SS, Boosani CS, Guha G, Ciriolo MR, Aquilano K, Chen S, Mohammed SI, Azmi AS, Bhakta D, Halicka D, Keith WN, Nowsheen S.

Semin Cancer Biol. 2015 Dec;35 Suppl:S25-S54. doi: 10.1016/j.semcancer.2015.02.006. Epub 2015 Apr 17. Review.

6.

Brk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4.

Patel P, Asbach B, Shteyn E, Gomez C, Coltoff A, Bhuyan S, Tyner AL, Wagner R, Blain SW.

Mol Cell Biol. 2015 May;35(9):1506-22. doi: 10.1128/MCB.01206-14. Epub 2015 Mar 2.

7.

Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma.

Hukkelhoven E, Liu Y, Yeh N, Ciznadija D, Blain SW, Koff A.

J Biol Chem. 2012 Nov 9;287(46):38523-30. doi: 10.1074/jbc.M112.366542. Epub 2012 Sep 24.

8.

Chk1 has an essential role in the survival of differentiated cortical neurons in the absence of DNA damage.

Ye W, Blain SW.

Apoptosis. 2011 May;16(5):449-59. doi: 10.1007/s10495-011-0579-z.

PMID:
21336968
9.

Inflammatory mediators of esophagitis alter p27 Kip1 expression in esophageal epithelial cells.

Nguyen KD, Blain SW, Gress F, Treem WR.

J Pediatr Gastroenterol Nutr. 2010 Nov;51(5):556-62. doi: 10.1097/MPG.0b013e3181ecd65d.

PMID:
20818264
10.
11.

p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.

Ray A, James MK, Larochelle S, Fisher RP, Blain SW.

Mol Cell Biol. 2009 Feb;29(4):986-99. doi: 10.1128/MCB.00898-08. Epub 2008 Dec 15.

12.

Switching cyclin D-Cdk4 kinase activity on and off.

Blain SW.

Cell Cycle. 2008 Apr 1;7(7):892-8. Epub 2008 Jan 18. Review.

PMID:
18414028
13.

Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity.

James MK, Ray A, Leznova D, Blain SW.

Mol Cell Biol. 2008 Jan;28(1):498-510. Epub 2007 Oct 1.

14.

p27 as a target for cancer therapeutics.

Blain SW, Scher HI, Cordon-Cardo C, Koff A.

Cancer Cell. 2003 Feb;3(2):111-5. Review. No abstract available.

15.

Breast cancer banishes p27 from nucleus.

Blain SW, Massagué J.

Nat Med. 2002 Oct;8(10):1076-8. No abstract available.

PMID:
12357238
16.

TGFbeta signaling in growth control, cancer, and heritable disorders.

Massagué J, Blain SW, Lo RS.

Cell. 2000 Oct 13;103(2):295-309. Review. No abstract available.

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