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Items: 1 to 50 of 131

1.

Loss-of-function variants in myocardin cause congenital megabladder in humans and mice.

Houweling AC, Beaman GM, Postma AV, Gainous TB, Lichtenbelt KD, Brancati F, Lopes FM, van der Made I, Polstra AM, Robinson ML, Wright KD, Ellingford JM, Jackson AR, Overwater E, Genesio R, Romano S, Camerota L, D'Angelo E, Meijers-Heijboer EJ, Christoffels VM, McHugh KM, Black BL, Newman WG, Woolf AS, Creemers EE.

J Clin Invest. 2019 Nov 4. pii: 128545. doi: 10.1172/JCI128545. [Epub ahead of print]

2.

Noncoding deletions reveal a gene that is critical for intestinal function.

Oz-Levi D, Olender T, Bar-Joseph I, Zhu Y, Marek-Yagel D, Barozzi I, Osterwalder M, Alkelai A, Ruzzo EK, Han Y, Vos ESM, Reznik-Wolf H, Hartman C, Shamir R, Weiss B, Shapiro R, Pode-Shakked B, Tatarskyy P, Milgrom R, Schvimer M, Barshack I, Imai DM, Coleman-Derr D, Dickel DE, Nord AS, Afzal V, van Bueren KL, Barnes RM, Black BL, Mayhew CN, Kuhar MF, Pitstick A, Tekman M, Stanescu HC, Wells JM, Kleta R, de Laat W, Goldstein DB, Pras E, Visel A, Lancet D, Anikster Y, Pennacchio LA.

Nature. 2019 Jul;571(7763):107-111. doi: 10.1038/s41586-019-1312-2. Epub 2019 Jun 19.

PMID:
31217582
3.

Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin.

Poltavski DM, Colombier P, Hu J, Duron A, Black BL, Makita T.

Elife. 2019 Feb 8;8. pii: e42528. doi: 10.7554/eLife.42528.

4.

Chemical neuroanatomy of the substantia nigra in the ovine brain.

Murray SJ, Black BL, Reid SJ, Rudiger SR, Simon Bawden C, Snell RG, Waldvogel HJ, Faull RLM.

J Chem Neuroanat. 2019 Apr;97:43-56. doi: 10.1016/j.jchemneu.2019.01.007. Epub 2019 Jan 18.

PMID:
30664938
5.

Cardiovascular development and survival require Mef2c function in the myocardial but not the endothelial lineage.

Materna SC, Sinha T, Barnes RM, Lammerts van Bueren K, Black BL.

Dev Biol. 2019 Jan 15;445(2):170-177. doi: 10.1016/j.ydbio.2018.12.002. Epub 2018 Dec 3.

PMID:
30521808
6.

Genomic analysis of transcriptional networks directing progression of cell states during MGE development.

Sandberg M, Taher L, Hu J, Black BL, Nord AS, Rubenstein JLR.

Neural Dev. 2018 Sep 14;13(1):21. doi: 10.1186/s13064-018-0119-4.

7.

Nodal Signaling and Congenital Heart Defects.

Barnes RM, Black BL.

In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 24.
2016 Jun 25.

8.

Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites.

Anderson CM, Hu J, Thomas R, Gainous TB, Celona B, Sinha T, Dickel DE, Heidt AB, Xu SM, Bruneau BG, Pollard KS, Pennacchio LA, Black BL.

Development. 2017 Apr 1;144(7):1235-1241. doi: 10.1242/dev.138487.

9.

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AA, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Smyth MJ, Cooper MA, Gambin Y, Francois M.

Elife. 2017 Jan 31;6. pii: e21221. doi: 10.7554/eLife.21221.

10.

Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106.

Celona B, Dollen JV, Vatsavayai SC, Kashima R, Johnson JR, Tang AA, Hata A, Miller BL, Huang EJ, Krogan NJ, Seeley WW, Black BL.

Elife. 2017 Jan 10;6. pii: e19032. doi: 10.7554/eLife.19032.

11.

Fast revascularization of the injured area is essential to support zebrafish heart regeneration.

Marín-Juez R, Marass M, Gauvrit S, Rossi A, Lai SL, Materna SC, Black BL, Stainier DY.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11237-11242. Epub 2016 Sep 19.

12.

Modulation of tissue repair by regeneration enhancer elements.

Kang J, Hu J, Karra R, Dickson AL, Tornini VA, Nachtrab G, Gemberling M, Goldman JA, Black BL, Poss KD.

Nature. 2016 Apr 14;532(7598):201-6. doi: 10.1038/nature17644. Epub 2016 Apr 6.

13.

MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1.

Barnes RM, Harris IS, Jaehnig EJ, Sauls K, Sinha T, Rojas A, Schachterle W, McCulley DJ, Norris RA, Black BL.

Development. 2016 Mar 1;143(5):774-9. doi: 10.1242/dev.126383. Epub 2016 Jan 25.

14.

Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway.

Hu J, Verzi MP, Robinson AS, Tang PL, Hua LL, Xu SM, Kwok PY, Black BL.

Development. 2015 Aug 15;142(16):2775-80. doi: 10.1242/dev.126391. Epub 2015 Jul 9.

15.

Identification of novel Fgf enhancers and their role in dental evolution.

Tapaltsyan V, Charles C, Hu J, Mindell D, Ahituv N, Wilson GM, Black BL, Viriot L, Klein OD.

Evol Dev. 2016 Jan-Feb;18(1):31-40. doi: 10.1111/ede.12132. Epub 2015 Jun 18.

16.

Developmental biology: Diversity in the lymphatic vasculature.

Hogan BM, Black BL.

Nature. 2015 Jun 4;522(7554):37-8. No abstract available.

PMID:
25992543
17.

Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells.

Aoto K, Sandell LL, Butler Tjaden NE, Yuen KC, Watt KE, Black BL, Durnin M, Trainor PA.

Dev Biol. 2015 Jun 1;402(1):3-16. doi: 10.1016/j.ydbio.2015.02.022. Epub 2015 Mar 17.

18.

Myocyte enhancer factor 2C function in skeletal muscle is required for normal growth and glucose metabolism in mice.

Anderson CM, Hu J, Barnes RM, Heidt AB, Cornelissen I, Black BL.

Skelet Muscle. 2015 Feb 27;5:7. doi: 10.1186/s13395-015-0031-0. eCollection 2015.

19.

NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity.

Ehlers ML, Celona B, Black BL.

Cell Rep. 2014 Sep 25;8(6):1639-1648. doi: 10.1016/j.celrep.2014.08.035. Epub 2014 Sep 18.

20.

An arterial-specific enhancer of the human endothelin converting enzyme 1 (ECE1) gene is synergistically activated by Sox17, FoxC2, and Etv2.

Robinson AS, Materna SC, Barnes RM, De Val S, Xu SM, Black BL.

Dev Biol. 2014 Nov 15;395(2):379-389. doi: 10.1016/j.ydbio.2014.08.027. Epub 2014 Aug 30.

21.

Specification of the mouse cardiac conduction system in the absence of Endothelin signaling.

Hua LL, Vedantham V, Barnes RM, Hu J, Robinson AS, Bressan M, Srivastava D, Black BL.

Dev Biol. 2014 Sep 15;393(2):245-254. doi: 10.1016/j.ydbio.2014.07.008. Epub 2014 Jul 19.

22.

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants.

Parker SC, Stitzel ML, Taylor DL, Orozco JM, Erdos MR, Akiyama JA, van Bueren KL, Chines PS, Narisu N; NISC Comparative Sequencing Program, Black BL, Visel A, Pennacchio LA, Collins FS; National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program Authors; NISC Comparative Sequencing Program Authors.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17921-6. doi: 10.1073/pnas.1317023110. Epub 2013 Oct 14.

23.

ETS factors regulate Vegf-dependent arterial specification.

Wythe JD, Dang LT, Devine WP, Boudreau E, Artap ST, He D, Schachterle W, Stainier DY, Oettgen P, Black BL, Bruneau BG, Fish JE.

Dev Cell. 2013 Jul 15;26(1):45-58. doi: 10.1016/j.devcel.2013.06.007. Epub 2013 Jul 3.

24.

Transcription factor pathways and congenital heart disease.

McCulley DJ, Black BL.

Curr Top Dev Biol. 2012;100:253-77. doi: 10.1016/B978-0-12-387786-4.00008-7. Review.

25.

Regulation of endothelial and hematopoietic development by the ETS transcription factor Etv2.

Lammerts van Bueren K, Black BL.

Curr Opin Hematol. 2012 May;19(3):199-205. doi: 10.1097/MOH.0b013e3283523e07. Review.

PMID:
22406820
26.

Large-scale discovery of enhancers from human heart tissue.

May D, Blow MJ, Kaplan T, McCulley DJ, Jensen BC, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Afzal V, Simpson PC, Rubin EM, Black BL, Bristow J, Pennacchio LA, Visel A.

Nat Genet. 2011 Dec 4;44(1):89-93. doi: 10.1038/ng.1006.

27.

ETS-dependent regulation of a distal Gata4 cardiac enhancer.

Schachterle W, Rojas A, Xu SM, Black BL.

Dev Biol. 2012 Jan 15;361(2):439-49. doi: 10.1016/j.ydbio.2011.10.023. Epub 2011 Oct 26.

28.

Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function.

Palencia-Desai S, Kohli V, Kang J, Chi NC, Black BL, Sumanas S.

Development. 2011 Nov;138(21):4721-32. doi: 10.1242/dev.064998.

29.

FGF-dependent regulation of VEGF receptor 2 expression in mice.

Murakami M, Nguyen LT, Hatanaka K, Schachterle W, Chen PY, Zhuang ZW, Black BL, Simons M.

J Clin Invest. 2011 Jul;121(7):2668-78. doi: 10.1172/JCI44762.

30.

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10.

Agarwal P, Verzi MP, Nguyen T, Hu J, Ehlers ML, McCulley DJ, Xu SM, Dodou E, Anderson JP, Wei ML, Black BL.

Development. 2011 Jun;138(12):2555-65. doi: 10.1242/dev.056804.

31.

Hand2 function in second heart field progenitors is essential for cardiogenesis.

Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H, Srivastava D.

Dev Biol. 2011 Mar 1;351(1):62-9. doi: 10.1016/j.ydbio.2010.12.023. Epub 2010 Dec 23.

32.

Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism.

Wang J, Greene SB, Bonilla-Claudio M, Tao Y, Zhang J, Bai Y, Huang Z, Black BL, Wang F, Martin JF.

Dev Cell. 2010 Dec 14;19(6):903-12. doi: 10.1016/j.devcel.2010.10.022.

33.

ChIP-Seq identification of weakly conserved heart enhancers.

Blow MJ, McCulley DJ, Li Z, Zhang T, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Wright C, Chen F, Afzal V, Bristow J, Ren B, Black BL, Rubin EM, Visel A, Pennacchio LA.

Nat Genet. 2010 Sep;42(9):806-10. doi: 10.1038/ng.650. Epub 2010 Aug 22.

34.

Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer.

Rojas A, Schachterle W, Xu SM, Martín F, Black BL.

Dev Biol. 2010 Oct 15;346(2):346-55. doi: 10.1016/j.ydbio.2010.07.032. Epub 2010 Aug 6.

35.

Developmental profile of claudin-3, -5, and -16 proteins in the epithelium of chick intestine.

Ozden O, Black BL, Ashwell CM, Tipsmark CK, Borski RJ, Grubb BJ.

Anat Rec (Hoboken). 2010 Jul;293(7):1175-83. doi: 10.1002/ar.21163.

36.

Development of the endocardium.

Harris IS, Black BL.

Pediatr Cardiol. 2010 Apr;31(3):391-9. doi: 10.1007/s00246-010-9642-8. Epub 2010 Feb 5. Review.

37.
38.

Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1.

Ha Choi J, Wah Yee S, Kim MJ, Nguyen L, Ho Lee J, Kang JO, Hesselson S, Castro RA, Stryke D, Johns SJ, Kwok PY, Ferrin TE, Goo Lee M, Black BL, Ahituv N, Giacomini KM.

Pharmacogenet Genomics. 2009 Oct;19(10):770-80. doi: 10.1097/FPC.0b013e328330eeca.

39.

Reptilian heart development and the molecular basis of cardiac chamber evolution.

Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges RO, Latham S, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK, Nemer M, Gilbert SF, Bruneau BG.

Nature. 2009 Sep 3;461(7260):95-8. doi: 10.1038/nature08324. Erratum in: Nature. 2009 Sep 24;461(7263):550. Beck, Laural [corrected to Beck, Laurel].

40.

Isl1 is a direct transcriptional target of Forkhead transcription factors in second-heart-field-derived mesoderm.

Kang J, Nathan E, Xu SM, Tzahor E, Black BL.

Dev Biol. 2009 Oct 15;334(2):513-22. doi: 10.1016/j.ydbio.2009.06.041. Epub 2009 Jul 4.

41.

Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins.

Lee Y, Hami D, De Val S, Kagermeier-Schenk B, Wills AA, Black BL, Weidinger G, Poss KD.

Dev Biol. 2009 Jul 15;331(2):270-80. doi: 10.1016/j.ydbio.2009.05.545. Epub 2009 May 13.

42.

Transcriptional control of endothelial cell development.

De Val S, Black BL.

Dev Cell. 2009 Feb;16(2):180-95. doi: 10.1016/j.devcel.2009.01.014. Review.

43.

Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).

Yee SW, Shima JE, Hesselson S, Nguyen L, De Val S, Lafond RJ, Kawamoto M, Johns SJ, Stryke D, Kwok PY, Ferrin TE, Black BL, Gurwitz D, Ahituv N, Giacomini KM.

J Pharmacol Exp Ther. 2009 Mar;328(3):699-707. doi: 10.1124/jpet.108.147207. Epub 2008 Dec 19.

44.

Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors.

De Val S, Chi NC, Meadows SM, Minovitsky S, Anderson JP, Harris IS, Ehlers ML, Agarwal P, Visel A, Xu SM, Pennacchio LA, Dubchak I, Krieg PA, Stainier DY, Black BL.

Cell. 2008 Dec 12;135(6):1053-64. doi: 10.1016/j.cell.2008.10.049.

45.

A p38 MAPK-MEF2C pathway regulates B-cell proliferation.

Khiem D, Cyster JG, Schwarz JJ, Black BL.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17067-72. doi: 10.1073/pnas.0804868105. Epub 2008 Oct 27.

46.
47.

GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.

Rojas A, Kong SW, Agarwal P, Gilliss B, Pu WT, Black BL.

Mol Cell Biol. 2008 Sep;28(17):5420-31. doi: 10.1128/MCB.00717-08. Epub 2008 Jun 30.

48.

Foxn4 directly regulates tbx2b expression and atrioventricular canal formation.

Chi NC, Shaw RM, De Val S, Kang G, Jan LY, Black BL, Stainier DY.

Genes Dev. 2008 Mar 15;22(6):734-9. doi: 10.1101/gad.1629408.

49.

Determinants of myogenic specificity within MyoD are required for noncanonical E box binding.

Heidt AB, Rojas A, Harris IS, Black BL.

Mol Cell Biol. 2007 Aug;27(16):5910-20. Epub 2007 Jun 11.

50.

The transcription factor MEF2C is required for craniofacial development.

Verzi MP, Agarwal P, Brown C, McCulley DJ, Schwarz JJ, Black BL.

Dev Cell. 2007 Apr;12(4):645-52.

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