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Items: 1 to 50 of 112

1.

Hepatocellular adenomas: is there additional value in using Gd-EOB-enhanced MRI for subtype differentiation?

Auer TA, Fehrenbach U, Grieser C, Penzkofer T, Geisel D, Schmelzle M, Müller T, Bläker H, Seehofer D, Denecke T.

Eur Radiol. 2020 Feb 21. doi: 10.1007/s00330-020-06726-8. [Epub ahead of print]

PMID:
32086574
2.

Postmenopausal hormone replacement therapy and colorectal cancer risk by molecular subtypes and pathways.

Amitay EL, Carr PR, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Int J Cancer. 2020 Jan 14. doi: 10.1002/ijc.32868. [Epub ahead of print]

PMID:
31943160
3.

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome.

Engel C, Ahadova A, Seppälä T, Aretz S, Bigirwamungu-Bargeman M, Bläker H, Bucksch K, Büttner R, de Vos Tot Nederveen Cappel W, Endris V, Holinski-Feder E, Holzapfel S, Hüneburg R, Jacobs MAJM, Koornstra JJ, Langers AM, Lepistö A, Morak M, Möslein G, Peltomäki P, Pylvänäinen K, Rahner N, Renkonen-Sinisalo L, Schulmann K, Steinke-Lange V, Stenzinger A, Strassburg CP, van de Meeberg PC, van Kouwen M, van Leerdam M, Vangala DB, Vecht J, Verhulst ML, von Knebel Doeberitz M, Weitz J, Zachariae S, Loeffler M, Mecklin JP, Kloor M, Vasen HF; German HNPCC Consortium, the Dutch Lynch Syndrome Collaborative Group, and the Finnish Lynch Syndrome Registry.

Gastroenterology. 2020 Jan 8. pii: S0016-5085(20)30014-7. doi: 10.1053/j.gastro.2019.12.032. [Epub ahead of print]

PMID:
31926173
4.

Association of BMI and major molecular pathological markers of colorectal cancer in men and women.

Carr PR, Amitay EL, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Schneider M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Am J Clin Nutr. 2020 Jan 3. pii: nqz315. doi: 10.1093/ajcn/nqz315. [Epub ahead of print]

PMID:
31897467
5.

Microsatellite instability and survival after adjuvant chemotherapy among stage II and III colon cancer patients: results from a population-based study.

Alwers E, Jansen L, Bläker H, Kloor M, Tagscherer KE, Roth W, Boakye D, Herpel E, Grüllich C, Chang-Claude J, Brenner H, Hoffmeister M.

Mol Oncol. 2020 Feb;14(2):363-372. doi: 10.1002/1878-0261.12611. Epub 2020 Jan 7.

6.

DNA methylation profiling to explore colorectal tumor differences according to menopausal hormone therapy use in women.

Neumeyer S, Popanda O, Butterbach K, Edelmann D, Bläker H, Toth C, Roth W, Herpel E, Jäkel C, Schmezer P, Benner A, Burwinkel B, Hoffmeister M, Brenner H, Chang-Claude J.

Epigenomics. 2019 Dec;11(16):1765-1778. doi: 10.2217/epi-2019-0051. Epub 2019 Nov 22.

PMID:
31755748
7.

[Meeting of the Gastroenteropathology Working Group of the German Society for Pathology : 103rd Annual Meeting of the German Society for Pathology, 13 June 2019, Frankfurt am Main].

Bläker H, Langer R.

Pathologe. 2019 Dec;40(Suppl 3):376-377. doi: 10.1007/s00292-019-00703-9. German. No abstract available.

PMID:
31705234
8.

A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival.

Jia M, Zhang Y, Jansen L, Walter V, Edelmann D, Gündert M, Tagscherer KE, Roth W, Bewerunge-Hudler M, Herpel E, Kloor M, Ulrich A, Burwinkel B, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Clin Epigenetics. 2019 Jul 24;11(1):109. doi: 10.1186/s13148-019-0703-4.

9.

External validation of molecular subtype classifications of colorectal cancer based on microsatellite instability, CIMP, BRAF and KRAS.

Alwers E, Bläker H, Walter V, Jansen L, Kloor M, Arnold A, Sieber-Frank J, Herpel E, Tagscherer KE, Roth W, Chang-Claude J, Brenner H, Hoffmeister M.

BMC Cancer. 2019 Jul 11;19(1):681. doi: 10.1186/s12885-019-5842-7.

10.

Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer.

Neumeyer S, Popanda O, Edelmann D, Butterbach K, Toth C, Roth W, Bläker H, Jiang R, Herpel E, Jäkel C, Schmezer P, Jansen L, Alwers E, Benner A, Burwinkel B, Hoffmeister M, Brenner H, Chang-Claude J.

Epigenetics. 2019 May;14(5):477-493. doi: 10.1080/15592294.2019.1595998. Epub 2019 Mar 30.

PMID:
30931802
11.

DNA methylation profiling reliably distinguishes pulmonary enteric adenocarcinoma from metastatic colorectal cancer.

Jurmeister P, Schöler A, Arnold A, Klauschen F, Lenze D, Hummel M, Schweizer L, Bläker H, Pfitzner BM, Mamlouk S, Sers C, Denkert C, Stichel D, Frost N, Horst D, von Laffert M, Capper D.

Mod Pathol. 2019 Jun;32(6):855-865. doi: 10.1038/s41379-019-0207-y. Epub 2019 Feb 5.

PMID:
30723296
12.

Tomoelastography for the Evaluation of Pediatric Nonalcoholic Fatty Liver Disease.

Hudert CA, Tzschätzsch H, Rudolph B, Bläker H, Loddenkemper C, Müller HP, Henning S, Bufler P, Hamm B, Braun J, Holzhütter HG, Wiegand S, Sack I, Guo J.

Invest Radiol. 2019 Apr;54(4):198-203. doi: 10.1097/RLI.0000000000000529.

PMID:
30444796
13.

Genetic determinants of steatosis and fibrosis progression in paediatric non-alcoholic fatty liver disease.

Hudert CA, Selinski S, Rudolph B, Bläker H, Loddenkemper C, Thielhorn R, Berndt N, Golka K, Cadenas C, Reinders J, Henning S, Bufler P, Jansen PLM, Holzhütter HG, Meierhofer D, Hengstler JG, Wiegand S.

Liver Int. 2019 Mar;39(3):540-556. doi: 10.1111/liv.14006. Epub 2018 Dec 21.

PMID:
30444569
14.

Association of Aspirin and Nonsteroidal Anti-Inflammatory Drugs With Colorectal Cancer Risk by Molecular Subtypes.

Amitay EL, Carr PR, Jansen L, Walter V, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

J Natl Cancer Inst. 2019 May 1;111(5):475-483. doi: 10.1093/jnci/djy170.

PMID:
30388256
15.

[Gastrointestinal tract diseases induced by medications].

Bläker H.

Pathologe. 2018 Nov;39(6):571-575. doi: 10.1007/s00292-018-0478-y. Review. German.

PMID:
30171343
16.

Experience with teduglutide treatment for short bowel syndrome in clinical practice.

Pevny S, Maasberg S, Rieger A, Karber M, Blüthner E, Knappe-Drzikova B, Thurmann D, Büttner J, Weylandt KH, Wiedenmann B, Müller VA, Bläker H, Pascher A, Pape UF.

Clin Nutr. 2019 Aug;38(4):1745-1755. doi: 10.1016/j.clnu.2018.07.030. Epub 2018 Aug 2.

PMID:
30145039
17.

US Time-Harmonic Elastography: Detection of Liver Fibrosis in Adolescents with Extreme Obesity with Nonalcoholic Fatty Liver Disease.

Hudert CA, Tzschätzsch H, Guo J, Rudolph B, Bläker H, Loddenkemper C, Luck W, Müller HP, Baumgart DC, Hamm B, Braun J, Holzhütter HG, Wiegand S, Sack I.

Radiology. 2018 Jul;288(1):99-106. doi: 10.1148/radiol.2018172928. Epub 2018 May 15.

PMID:
29762096
18.

Tumour buds determine prognosis in resected pancreatic ductal adenocarcinoma.

Lohneis P, Sinn M, Klein F, Bischoff S, Striefler JK, Wislocka L, Sinn BV, Pelzer U, Oettle H, Riess H, Denkert C, Bläker H, Jühling A.

Br J Cancer. 2018 May;118(11):1485-1491. doi: 10.1038/s41416-018-0093-y. Epub 2018 May 14.

19.

The Association Between Mutations in BRAF and Colorectal Cancer-Specific Survival Depends on Microsatellite Status and Tumor Stage.

Bläker H, Alwers E, Arnold A, Herpel E, Tagscherer KE, Roth W, Jansen L, Walter V, Kloor M, Chang-Claude J, Brenner H, Hoffmeister M.

Clin Gastroenterol Hepatol. 2019 Feb;17(3):455-462.e6. doi: 10.1016/j.cgh.2018.04.015. Epub 2018 Apr 13.

PMID:
29660527
20.

Two patients with rare mixed adenoneuroendocrine carcinomas of the rectum.

Gül-Klein S, Sinn M, Jurmeister PS, Biebl M, Weiß S, Rau B, Bläker H, Pratschke J, Aigner F.

SAGE Open Med Case Rep. 2018 Mar 14;6:2050313X18758816. doi: 10.1177/2050313X18758816. eCollection 2018.

21.

Three molecular pathways model colorectal carcinogenesis in Lynch syndrome.

Ahadova A, Gallon R, Gebert J, Ballhausen A, Endris V, Kirchner M, Stenzinger A, Burn J, von Knebel Doeberitz M, Bläker H, Kloor M.

Int J Cancer. 2018 Jul 1;143(1):139-150. doi: 10.1002/ijc.31300. Epub 2018 Feb 23.

22.

[Ichthyosis uteri (psoriasis uteri) : A very rare disorder].

von Laffert M, Elezkurtaj S, Sehouli J, Barinoff J, Boschetti Grützmacher E, Arsenic R, Bläker H.

Pathologe. 2018 May;39(3):264-268. doi: 10.1007/s00292-017-0403-9. German.

PMID:
29313082
23.

Associations Between Molecular Classifications of Colorectal Cancer and Patient Survival: A Systematic Review.

Alwers E, Jia M, Kloor M, Bläker H, Brenner H, Hoffmeister M.

Clin Gastroenterol Hepatol. 2019 Feb;17(3):402-410.e2. doi: 10.1016/j.cgh.2017.12.038. Epub 2018 Jan 3. Review.

PMID:
29306042
24.

Cytotoxic tumour-infiltrating T lymphocytes influence outcome in resected pancreatic ductal adenocarcinoma.

Lohneis P, Sinn M, Bischoff S, Jühling A, Pelzer U, Wislocka L, Bahra M, Sinn BV, Denkert C, Oettle H, Bläker H, Riess H, Jöhrens K, Striefler JK.

Eur J Cancer. 2017 Sep;83:290-301. doi: 10.1016/j.ejca.2017.06.016. Epub 2017 Jul 31.

PMID:
28772128
25.

Associations of red and processed meat intake with major molecular pathological features of colorectal cancer.

Carr PR, Jansen L, Bienert S, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Eur J Epidemiol. 2017 May;32(5):409-418. doi: 10.1007/s10654-017-0275-6. Epub 2017 Jun 23.

PMID:
28646407
26.

The association between microsatellite instability and lymph node count in colorectal cancer.

Arnold A, Kloor M, Jansen L, Chang-Claude J, Brenner H, von Winterfeld M, Hoffmeister M, Bläker H.

Virchows Arch. 2017 Jul;471(1):57-64. doi: 10.1007/s00428-017-2150-y. Epub 2017 May 23.

PMID:
28536779
27.

DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer.

Mamlouk S, Childs LH, Aust D, Heim D, Melching F, Oliveira C, Wolf T, Durek P, Schumacher D, Bläker H, von Winterfeld M, Gastl B, Möhr K, Menne A, Zeugner S, Redmer T, Lenze D, Tierling S, Möbs M, Weichert W, Folprecht G, Blanc E, Beule D, Schäfer R, Morkel M, Klauschen F, Leser U, Sers C.

Nat Commun. 2017 Jan 25;8:14093. doi: 10.1038/ncomms14093.

28.

Poorly Differentiated Medullary Phenotype Predicts Poor Survival in Early Lymph Node-Negative Gastro-Esophageal Adenocarcinomas.

Treese C, Sanchez P, Grabowski P, Berg E, Bläker H, Kruschewski M, Haase O, Hummel M, Daum S.

PLoS One. 2016 Dec 28;11(12):e0168237. doi: 10.1371/journal.pone.0168237. eCollection 2016.

29.

No association of CpG island methylator phenotype and colorectal cancer survival: population-based study.

Jia M, Jansen L, Walter V, Tagscherer K, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Br J Cancer. 2016 Nov 22;115(11):1359-1366. doi: 10.1038/bjc.2016.361. Epub 2016 Nov 3.

30.

Prognostic relevance of prediagnostic weight loss and overweight at diagnosis in patients with colorectal cancer.

Walter V, Jansen L, Hoffmeister M, Ulrich A, Roth W, Bläker H, Chang-Claude J, Brenner H.

Am J Clin Nutr. 2016 Oct;104(4):1110-1120. Epub 2016 Aug 31.

PMID:
27581471
31.

SPARC expression in resected pancreatic cancer patients treated with Gemcitabine: results from the CONKO-001 study.

Sinn M, Sinn BV, Striefler JK, Lindner JL, Stieler JM, Lohneis P, Bischoff S, Bläker H, Pelzer U, Bahra M, Dietel M, Dörken B, Oettle H, Riess H, Denkert C.

Ann Oncol. 2017 Nov 1;28(11):2900. doi: 10.1093/annonc/mdw269. No abstract available.

32.

P53 overexpression and Ki67-index are associated with outcome in ductal pancreatic adenocarcinoma with adjuvant gemcitabine treatment.

Striefler JK, Sinn M, Pelzer U, Jühling A, Wislocka L, Bahra M, Sinn BV, Denkert C, Dörken B, Oettle H, Riess H, Bläker H, Lohneis P.

Pathol Res Pract. 2016 Aug;212(8):726-34. doi: 10.1016/j.prp.2016.06.001. Epub 2016 Jun 8.

PMID:
27461834
33.

[Grading of tumors in the tubular digestive tract : Esophagus, stomach, colon and rectum].

Bläker H.

Pathologe. 2016 Jul;37(4):293-8. doi: 10.1007/s00292-016-0165-9. Review. German.

PMID:
27255228
34.

Alcohol consumption and survival of colorectal cancer patients: a population-based study from Germany.

Walter V, Jansen L, Ulrich A, Roth W, Bläker H, Chang-Claude J, Hoffmeister M, Brenner H.

Am J Clin Nutr. 2016 Jun;103(6):1497-506. doi: 10.3945/ajcn.115.127092. Epub 2016 May 4.

PMID:
27146651
35.

CTNNB1-mutant colorectal carcinomas with immediate invasive growth: a model of interval cancers in Lynch syndrome.

Ahadova A, von Knebel Doeberitz M, Bläker H, Kloor M.

Fam Cancer. 2016 Oct;15(4):579-86. doi: 10.1007/s10689-016-9899-z.

PMID:
26960970
36.

Re: "Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course".

Klauschen F, Bläker H, Stenzinger A, Chapman JS, Collisson EA, Taylor BS.

J Natl Compr Canc Netw. 2016 Mar;14(3):lxvi-lxviii. No abstract available.

PMID:
26957621
37.

Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer.

Roßner F, Gieseler C, Morkel M, Royer HD, Rivera M, Bläker H, Dietel M, Schäfer R, Sers C.

Oncogenesis. 2016 Jan 18;5:e187. doi: 10.1038/oncsis.2015.51.

38.

MACC1 Induces Tumor Progression in Transgenic Mice and Colorectal Cancer Patients via Increased Pluripotency Markers Nanog and Oct4.

Lemos C, Hardt MS, Juneja M, Voss C, Förster S, Jerchow B, Haider W, Bläker H, Stein U.

Clin Cancer Res. 2016 Jun 1;22(11):2812-24. doi: 10.1158/1078-0432.CCR-15-1425. Epub 2016 Jan 12.

39.

Associations of red and processed meat with survival after colorectal cancer and differences according to timing of dietary assessment.

Carr PR, Jansen L, Walter V, Kloor M, Roth W, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Am J Clin Nutr. 2016 Jan;103(1):192-200. doi: 10.3945/ajcn.115.121145. Epub 2015 Nov 25.

PMID:
26607936
40.

Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy.

Pfütze K, Benner A, Hoffmeister M, Jansen L, Yang R, Bläker H, Herpel E, Ulrich A, Ulrich CM, Chang-Claude J, Brenner H, Burwinkel B.

Genomics. 2015 Dec;106(6):348-54. doi: 10.1016/j.ygeno.2015.10.002. Epub 2015 Oct 21.

41.

A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics.

Sadanandam A, Wullschleger S, Lyssiotis CA, Grötzinger C, Barbi S, Bersani S, Körner J, Wafy I, Mafficini A, Lawlor RT, Simbolo M, Asara JM, Bläker H, Cantley LC, Wiedenmann B, Scarpa A, Hanahan D.

Cancer Discov. 2015 Dec;5(12):1296-313. doi: 10.1158/2159-8290.CD-15-0068. Epub 2015 Oct 7.

42.

CT and MRI Findings of Autoimmune Polymorph Bifocal Pancreatitis Mimicking Pancreatic Adenocarcinoma: A Case Report and Review of the Literature.

Rotzinger R, Bläker H, Bahra M, Denecke T, Grieser C.

J Investig Med High Impact Case Rep. 2015 Mar 16;3(1):2324709615576988. doi: 10.1177/2324709615576988. eCollection 2015 Jan-Mar.

43.

A 2015 update on predictive molecular pathology and its role in targeted cancer therapy: a review focussing on clinical relevance.

Dietel M, Jöhrens K, Laffert MV, Hummel M, Bläker H, Pfitzner BM, Lehmann A, Denkert C, Darb-Esfahani S, Lenze D, Heppner FL, Koch A, Sers C, Klauschen F, Anagnostopoulos I.

Cancer Gene Ther. 2015 Sep;22(9):417-30. doi: 10.1038/cgt.2015.39. Epub 2015 Sep 11. Review.

PMID:
26358176
44.
45.

Genome wide DNA copy number analysis in cholangiocarcinoma using high resolution molecular inversion probe single nucleotide polymorphism assay.

Arnold A, Bahra M, Lenze D, Bradtmöller M, Guse K, Gehlhaar C, Bläker H, Heppner FL, Koch A.

Exp Mol Pathol. 2015 Oct;99(2):344-53. doi: 10.1016/j.yexmp.2015.08.003. Epub 2015 Aug 8.

PMID:
26260902
46.

Human equilibrative nucleoside transporter 1 expression analysed by the clone SP 120 rabbit antibody is not predictive in patients with pancreatic cancer treated with adjuvant gemcitabine - Results from the CONKO-001 trial.

Sinn M, Riess H, Sinn BV, Stieler JM, Pelzer U, Striefler JK, Oettle H, Bahra M, Denkert C, Bläker H, Lohneis P.

Eur J Cancer. 2015 Aug;51(12):1546-54. doi: 10.1016/j.ejca.2015.05.005. Epub 2015 Jun 3.

PMID:
26049689
47.

Overexpression of SIX1 is an independent prognostic marker in stage I-III colorectal cancer.

Kahlert C, Lerbs T, Pecqueux M, Herpel E, Hoffmeister M, Jansen L, Brenner H, Chang-Claude J, Bläker H, Kloor M, Roth W, Pilarsky C, Rahbari NN, Schölch S, Bork U, Reissfelder C, Weitz J, Aust D, Koch M.

Int J Cancer. 2015 Nov 1;137(9):2104-13. doi: 10.1002/ijc.29596. Epub 2015 May 21.

48.

[Remove polyps and discard. Way or wrong way?].

Tannapfel A, Aust D, Baretton GB, Bläker H, Esposito I, Langner C, Vieth M, Wardelmann E, Kirchner T, Schirmacher P.

Pathologe. 2015 Mar;36(2):182-5. doi: 10.1007/s00292-015-0003-5. German. No abstract available.

PMID:
25855462
49.

[Histological diagnosis and complications of celiac disease. Update according to the new S2k guidelines].

Aust DE, Bläker H.

Pathologe. 2015 Mar;36(2):197-205; quiz 206-7. doi: 10.1007/s00292-015-0006-2. Review. German.

PMID:
25820446
50.

Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters.

Staffa L, Echterdiek F, Nelius N, Benner A, Werft W, Lahrmann B, Grabe N, Schneider M, Tariverdian M, von Knebel Doeberitz M, Bläker H, Kloor M.

PLoS One. 2015 Mar 27;10(3):e0121980. doi: 10.1371/journal.pone.0121980. eCollection 2015.

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