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Items: 4

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1.

Identification of pyrazolopyridazinones as PDEδ inhibitors.

Papke B, Murarka S, Vogel HA, Martín-Gago P, Kovacevic M, Truxius DC, Fansa EK, Ismail S, Zimmermann G, Heinelt K, Schultz-Fademrecht C, Al Saabi A, Baumann M, Nussbaumer P, Wittinghofer A, Waldmann H, Bastiaens PI.

Nat Commun. 2016 Apr 20;7:11360. doi: 10.1038/ncomms11360.

2.

KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport.

Schmick M, Vartak N, Papke B, Kovacevic M, Truxius DC, Rossmannek L, Bastiaens PIH.

Cell. 2014 Apr 10;157(2):459-471. doi: 10.1016/j.cell.2014.02.051.

3.

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling.

Zimmermann G, Papke B, Ismail S, Vartak N, Chandra A, Hoffmann M, Hahn SA, Triola G, Wittinghofer A, Bastiaens PI, Waldmann H.

Nature. 2013 May 30;497(7451):638-42. doi: 10.1038/nature12205. Epub 2013 May 22.

PMID:
23698361
4.

Precise measurement of protein interacting fractions with fluorescence lifetime imaging microscopy.

Walther KA, Papke B, Sinn MB, Michel K, Kinkhabwala A.

Mol Biosyst. 2011 Feb;7(2):322-36. doi: 10.1039/c0mb00132e. Epub 2011 Jan 10.

PMID:
21221430

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