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Items: 1 to 50 of 177

1.

Oxygen Restriction Generates Difficult-to-Culture P. aeruginosa.

Kvich L, Fritz B, Crone S, Kragh KN, Kolpen M, Sønderholm M, Andersson M, Koch A, Jensen PØ, Bjarnsholt T.

Front Microbiol. 2019 Aug 29;10:1992. doi: 10.3389/fmicb.2019.01992. eCollection 2019.

2.

Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction.

Bjarnsholt T, Jensen PØ, Alhede M.

Pathog Dis. 2019 Jul 1;77(5). pii: ftz052. doi: 10.1093/femspd/ftz052.

PMID:
31529027
3.

Pathogenic CD8+ epidermis-resident memory T cells displace dendritic epidermal T cells in allergic dermatitis.

Ø Gadsbøll AS, Jee MH, Funch AB, Alhede M, Mraz V, Weber JF, Callender LA, Carroll EC, Bjarnsholt T, Woetmann A, Ødum N, Thomsen AR, Johansen JD, Henson SM, Geisler C, Bonefeld CM.

J Invest Dermatol. 2019 Sep 10. pii: S0022-202X(19)33218-X. doi: 10.1016/j.jid.2019.07.722. [Epub ahead of print]

PMID:
31518559
4.

An Equine Wound Model to Study Effects of Bacterial Aggregates on Wound Healing.

Jørgensen E, Bay L, Skovgaard LT, Bjarnsholt T, Jacobsen S.

Adv Wound Care (New Rochelle). 2019 Oct 1;8(10):487-498. doi: 10.1089/wound.2018.0901. Epub 2019 Aug 21.

5.

Analysis of proximal bone margins in diabetic foot osteomyelitis by conventional culture, DNA sequencing and microscopy.

Malone M, Fritz BG, Vickery K, Schwarzer S, Sharma V, Biggs N, Radzieta M, Jeffries TT, Dickson HG, Jensen SO, Bjarnsholt T.

APMIS. 2019 Oct;127(10):660-670. doi: 10.1111/apm.12986. Epub 2019 Aug 28.

PMID:
31344275
6.

Antimicrobial Tolerance and Metabolic Adaptations in Microbial Biofilms.

Crabbé A, Jensen PØ, Bjarnsholt T, Coenye T.

Trends Microbiol. 2019 Oct;27(10):850-863. doi: 10.1016/j.tim.2019.05.003. Epub 2019 Jun 6. Review.

PMID:
31178124
7.

Is pseudarthrosis after spinal instrumentation caused by a chronic infection?

Ohrt-Nissen S, Fritz B, Valentin L, Kragh KN, Manniche C, Dahl B, Bjarnsholt T.

Eur Spine J. 2019 May 13. doi: 10.1007/s00586-019-06004-2. [Epub ahead of print]

PMID:
31087166
8.

Shotgun sequencing of clinical biofilm following scanning electron microscopy identifies bacterial community composition.

Fritz B, Stavnsbjerg C, Markvart M, Damgaard PB, Nielsen SH, Bjørndal L, Qvortrup K, Bjarnsholt T.

Pathog Dis. 2019 Feb 1;77(1). pii: ftz013. doi: 10.1093/femspd/ftz013.

PMID:
30844070
9.

Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients.

Møller SA, Jensen PØ, Høiby N, Ciofu O, Kragh KN, Bjarnsholt T, Kolpen M.

J Cyst Fibros. 2019 Sep;18(5):657-664. doi: 10.1016/j.jcf.2019.01.005. Epub 2019 Jan 31.

PMID:
30711384
10.

Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth.

Høiby N, Henneberg KÅ, Wang H, Stavnsbjerg C, Bjarnsholt T, Ciofu O, Johansen UR, Sams T.

Int J Antimicrob Agents. 2019 May;53(5):564-573. doi: 10.1016/j.ijantimicag.2018.12.015. Epub 2019 Jan 5.

11.

In Vivo Gentamicin Susceptibility Test for Prevention of Bacterial Biofilms in Bone Tissue and on Implants.

Jensen LK, Bjarnsholt T, Kragh KN, Aalbæk B, Henriksen NL, Blirup SA, Pankoke K, Petersen A, Jensen HE.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01889-18. doi: 10.1128/AAC.01889-18. Print 2019 Feb.

12.

[Interaction between microbiota and immune system in colorectal cancer].

Raskov H, Bjarnsholt T, Alamili M, Kragh KN, Gögenur I.

Ugeskr Laeger. 2018 Nov 5;180(45). pii: V04180253. Danish.

PMID:
30404713
13.

UV light assisted antibiotics for eradication of in vitro biofilms.

Argyraki A, Markvart M, Stavnsbjerg C, Kragh KN, Ou Y, Bjørndal L, Bjarnsholt T, Petersen PM.

Sci Rep. 2018 Nov 5;8(1):16360. doi: 10.1038/s41598-018-34340-8.

14.

Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis.

Raskov H, Kragh KN, Bjarnsholt T, Alamili M, Gögenur I.

Clin Transl Med. 2018 Sep 17;7(1):30. doi: 10.1186/s40169-018-0209-2.

15.

The use of fluorescent staining techniques for microscopic investigation of polymorphonuclear leukocytes and bacteria.

Alhede M, Stavnsbjerg C, Bjarnsholt T.

APMIS. 2018 Oct;126(10):779-794. doi: 10.1111/apm.12888. Epub 2018 Sep 6. Review.

PMID:
30191615
16.

Morphological evidence of biofilm in chronic obstructive sialadenitis.

Schrøder SA, Eickhardt S, Bjarnsholt T, Nørgaard T, Homøe P.

J Laryngol Otol. 2018 Jul;132(7):611-614. doi: 10.1017/S0022215118000646. Epub 2018 Jul 10.

PMID:
29986787
17.

Implants induce a new niche for microbiomes.

Jakobsen TH, Eickhardt SR, Gheorghe AG, Stenqvist C, Sønderholm M, Stavnsberg C, Jensen PØ, Odgaard A, Whiteley M, Moser C, Hvolris J, Hougen HP, Bjarnsholt T.

APMIS. 2018 Aug;126(8):685-692. doi: 10.1111/apm.12862. Epub 2018 Jul 2.

PMID:
29962006
18.

Biofilm formation - what we can learn from recent developments.

Bjarnsholt T, Buhlin K, Dufrêne YF, Gomelsky M, Moroni A, Ramstedt M, Rumbaugh KP, Schulte T, Sun L, Åkerlund B, Römling U.

J Intern Med. 2018 Oct;284(4):332-345. doi: 10.1111/joim.12782. Epub 2018 Jul 9.

19.

Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches.

Johani K, Fritz BG, Bjarnsholt T, Lipsky BA, Jensen SO, Yang M, Dean A, Hu H, Vickery K, Malone M.

Clin Microbiol Infect. 2019 Mar;25(3):332-339. doi: 10.1016/j.cmi.2018.04.036. Epub 2018 May 19.

PMID:
29787888
20.

Pseudomonas aeruginosa transcriptome during human infection.

Cornforth DM, Dees JL, Ibberson CB, Huse HK, Mathiesen IH, Kirketerp-Møller K, Wolcott RD, Rumbaugh KP, Bjarnsholt T, Whiteley M.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5125-E5134. doi: 10.1073/pnas.1717525115. Epub 2018 May 14.

21.

Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin.

Woetmann A, Alhede M, Dabelsteen S, Bjarnsholt T, Rybtke M, Nastasi C, Krejsgaard T, Andersen MH, Bonefeld CM, Geisler C, Givskov M, Odum N.

Oncotarget. 2018 Apr 13;9(28):19481-19489. doi: 10.18632/oncotarget.24603. eCollection 2018 Apr 13.

22.

Bacterial biofilms: a possible mechanism for chronic infection in patients with lumbar disc herniation - a prospective proof-of-concept study using fluorescence in situ hybridization.

Ohrt-Nissen S, Fritz BG, Walbom J, Kragh KN, Bjarnsholt T, Dahl B, Manniche C.

APMIS. 2018 May;126(5):440-447. doi: 10.1111/apm.12841.

PMID:
29696720
23.

Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds.

Bay L, Kragh KN, Eickhardt SR, Poulsen SS, Gjerdrum LMR, Ghathian K, Calum H, Ågren MS, Bjarnsholt T.

Adv Wound Care (New Rochelle). 2018 Apr 1;7(4):105-113. doi: 10.1089/wound.2017.0770.

24.

Combined Staining Techniques for Demonstration of Staphylococcus aureus Biofilm in Routine Histopathology.

Jensen LK, Henriksen NL, Bjarnsholt T, Kragh KN, Jensen HE.

J Bone Jt Infect. 2018 Feb 20;3(1):27-36. doi: 10.7150/jbji.22799. eCollection 2018.

25.

Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model.

Sønderholm M, Koren K, Wangpraseurt D, Jensen PØ, Kolpen M, Kragh KN, Bjarnsholt T, Kühl M.

NPJ Biofilms Microbiomes. 2018 Feb 19;4:3. doi: 10.1038/s41522-018-0047-4. eCollection 2018.

26.

Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?

Coenye T, Goeres D, Van Bambeke F, Bjarnsholt T.

Clin Microbiol Infect. 2018 Jun;24(6):570-572. doi: 10.1016/j.cmi.2018.01.003. Epub 2018 Jan 11. No abstract available.

27.

The Inoculation Method Could Impact the Outcome of Microbiological Experiments.

Kragh KN, Alhede M, Rybtke M, Stavnsberg C, Jensen PØ, Tolker-Nielsen T, Whiteley M, Bjarnsholt T.

Appl Environ Microbiol. 2018 Feb 14;84(5). pii: e02264-17. doi: 10.1128/AEM.02264-17. Print 2018 Mar 1.

28.

The Consequences of Being in an Infectious Biofilm: Microenvironmental Conditions Governing Antibiotic Tolerance.

Sønderholm M, Bjarnsholt T, Alhede M, Kolpen M, Jensen PØ, Kühl M, Kragh KN.

Int J Mol Sci. 2017 Dec 12;18(12). pii: E2688. doi: 10.3390/ijms18122688. Review.

29.

Heading for centennial anniversary and beyond.

Norrild B, Ralfkiaer E, Bjarnsholt T, Jensen PØ.

APMIS. 2017 Dec;125(12):1133. doi: 10.1111/apm.12797. No abstract available.

PMID:
29193348
30.

Qualitative and Quantitative Determination of Quorum Sensing Inhibition In Vitro.

Jakobsen TH, Alhede M, Hultqvist LD, Bjarnsholt T, Givskov M.

Methods Mol Biol. 2018;1673:275-285. doi: 10.1007/978-1-4939-7309-5_21.

PMID:
29130180
31.

Imaging N-Acyl Homoserine Lactone Quorum Sensing In Vivo.

Hultqvist LD, Alhede M, Jakobsen TH, Givskov M, Bjarnsholt T.

Methods Mol Biol. 2018;1673:203-212. doi: 10.1007/978-1-4939-7309-5_16.

PMID:
29130175
32.

Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds.

Schultz G, Bjarnsholt T, James GA, Leaper DJ, McBain AJ, Malone M, Stoodley P, Swanson T, Tachi M, Wolcott RD; Global Wound Biofilm Expert Panel.

Wound Repair Regen. 2017 Sep;25(5):744-757. doi: 10.1111/wrr.12590. Epub 2017 Dec 12. Review.

PMID:
28960634
33.

Hyperbaric Oxygen Sensitizes Anoxic Pseudomonas aeruginosa Biofilm to Ciprofloxacin.

Kolpen M, Lerche CJ, Kragh KN, Sams T, Koren K, Jensen AS, Line L, Bjarnsholt T, Ciofu O, Moser C, Kühl M, Høiby N, Jensen PØ.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01024-17. doi: 10.1128/AAC.01024-17. Print 2017 Nov.

34.

Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls.

Ring HC, Thorsen J, Saunte DM, Lilje B, Bay L, Theut Riis P, Larsen N, O'Brien Andersen L, Vedel Nielsen H, Miller IM, Bjarnsholt T, Fuursted K, Jemec GB.

J Eur Acad Dermatol Venereol. 2018 Jan;32(1):125-128. doi: 10.1111/jdv.14538. Epub 2017 Sep 12.

PMID:
28833590
35.

Inactivation of Pseudomonas aeruginosa biofilm after ultraviolet light-emitting diode treatment: a comparative study between ultraviolet C and ultraviolet B.

Argyraki A, Markvart M, Bjørndal L, Bjarnsholt T, Petersen PM.

J Biomed Opt. 2017 Jun 1;22(6):65004. doi: 10.1117/1.JBO.22.6.065004.

36.

The Pseudomonas aeruginosa PSL Polysaccharide Is a Social but Noncheatable Trait in Biofilms.

Irie Y, Roberts AEL, Kragh KN, Gordon VD, Hutchison J, Allen RJ, Melaugh G, Bjarnsholt T, West SA, Diggle SP.

MBio. 2017 Jun 20;8(3). pii: e00374-17. doi: 10.1128/mBio.00374-17.

37.

The Follicular Skin Microbiome in Patients With Hidradenitis Suppurativa and Healthy Controls.

Ring HC, Thorsen J, Saunte DM, Lilje B, Bay L, Riis PT, Larsen N, Andersen LO, Nielsen HV, Miller IM, Bjarnsholt T, Fuursted K, Jemec GB.

JAMA Dermatol. 2017 Sep 1;153(9):897-905. doi: 10.1001/jamadermatol.2017.0904.

38.

The occurrence of biofilm in an equine experimental wound model of healing by secondary intention.

Jørgensen E, Bay L, Bjarnsholt T, Bundgaard L, Sørensen MA, Jacobsen S.

Vet Microbiol. 2017 May;204:90-95. doi: 10.1016/j.vetmic.2017.03.011. Epub 2017 Mar 9.

PMID:
28532812
39.

Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

Jensen RG, Johansen HK, Bjarnsholt T, Eickhardt-Sørensen SR, Homøe P.

Eur Arch Otorhinolaryngol. 2017 Jul;274(7):2741-2747. doi: 10.1007/s00405-017-4586-8. Epub 2017 May 2.

PMID:
28466356
40.

Diagnosis of biofilm infections in cystic fibrosis patients.

Høiby N, Bjarnsholt T, Moser C, Jensen PØ, Kolpen M, Qvist T, Aanaes K, Pressler T, Skov M, Ciofu O.

APMIS. 2017 Apr;125(4):339-343. doi: 10.1111/apm.12689. Review.

PMID:
28407432
41.

Phage Inhibit Pathogen Dissemination by Targeting Bacterial Migrants in a Chronic Infection Model.

Darch SE, Kragh KN, Abbott EA, Bjarnsholt T, Bull JJ, Whiteley M.

MBio. 2017 Apr 4;8(2). pii: e00240-17. doi: 10.1128/mBio.00240-17.

42.

Comparison of two commercial broad-range PCR and sequencing assays for identification of bacteria in culture-negative clinical samples.

Stavnsbjerg C, Frimodt-Møller N, Moser C, Bjarnsholt T.

BMC Infect Dis. 2017 Mar 27;17(1):233. doi: 10.1186/s12879-017-2333-9.

44.

Pseudomonas aeruginosa Aggregate Formation in an Alginate Bead Model System Exhibits In Vivo-Like Characteristics.

Sønderholm M, Kragh KN, Koren K, Jakobsen TH, Darch SE, Alhede M, Jensen PØ, Whiteley M, Kühl M, Bjarnsholt T.

Appl Environ Microbiol. 2017 Apr 17;83(9). pii: e00113-17. doi: 10.1128/AEM.00113-17. Print 2017 May 1.

45.

The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data.

Malone M, Bjarnsholt T, McBain AJ, James GA, Stoodley P, Leaper D, Tachi M, Schultz G, Swanson T, Wolcott RD.

J Wound Care. 2017 Jan 2;26(1):20-25. doi: 10.12968/jowc.2017.26.1.20. Review.

PMID:
28103163
46.

Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response.

Jensen LK, Koch J, Dich-Jorgensen K, Aalbaek B, Petersen A, Fuursted K, Bjarnsholt T, Kragh KN, Tøtterup M, Bue M, Hanberg P, Søballe K, Heegaard PMH, Jensen HE.

J Orthop Res. 2017 Oct;35(10):2211-2221. doi: 10.1002/jor.23505. Epub 2017 Jan 15.

47.

Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections.

Rudkjøbing VB, Thomsen TR, Xu Y, Melton-Kreft R, Ahmed A, Eickhardt S, Bjarnsholt T, Poulsen SS, Nielsen PH, Earl JP, Ehrlich GD, Moser C.

BMC Infect Dis. 2016 Nov 8;16(1):652.

48.

Maxillary Sinus Impaction of a Core Carrier Causing Sustained Apical Periodontitis, Sinusitis, and Nasal Stenosis: A 3-year Follow-up.

Bjørndal L, Amaloo C, Markvart M, Rud V, Qvortrup K, Stavnsbjerg C, Bjarnsholt T.

J Endod. 2016 Dec;42(12):1851-1858. doi: 10.1016/j.joen.2016.07.027. Epub 2016 Oct 18.

PMID:
27769679
49.

Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir.

Jensen LK, Koch J, Aalbaek B, Moodley A, Bjarnsholt T, Kragh KN, Petersen A, Jensen HE.

APMIS. 2017 Jan;125(1):38-45. doi: 10.1111/apm.12597. Epub 2016 Oct 5.

50.

Achromobacter Species Isolated from Cystic Fibrosis Patients Reveal Distinctly Different Biofilm Morphotypes.

Nielsen SM, Nørskov-Lauritsen N, Bjarnsholt T, Meyer RL.

Microorganisms. 2016 Sep 14;4(3). pii: E33. doi: 10.3390/microorganisms4030033.

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