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Items: 1 to 50 of 171

1.

Shotgun sequencing of clinical biofilm following scanning electron microscopy identifies bacterial community composition.

Fritz B, Stavnsbjerg C, Markvart M, Damgaard PB, Nielsen SH, Bjørndal L, Qvortrup K, Bjarnsholt T.

Pathog Dis. 2019 Mar 7. pii: ftz013. doi: 10.1093/femspd/ftz013. [Epub ahead of print]

PMID:
30844070
2.

Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients.

Møller SA, Jensen PØ, Høiby N, Ciofu O, Kragh KN, Bjarnsholt T, Kolpen M.

J Cyst Fibros. 2019 Jan 30. pii: S1569-1993(19)30011-6. doi: 10.1016/j.jcf.2019.01.005. [Epub ahead of print]

PMID:
30711384
3.

Formation of Pseudomonas aeruginosa inhibition zone during Tobramycin disk diffusion is due to a transition from planktonic to biofilm mode of growth.

Høiby N, Henneberg KÅ, Wang H, Stavnsbjerg C, Bjarnsholt T, Ciofu O, Johansen UR, Sams T.

Int J Antimicrob Agents. 2019 Jan 4. pii: S0924-8579(18)30385-6. doi: 10.1016/j.ijantimicag.2018.12.015. [Epub ahead of print]

4.

In Vivo Gentamicin Susceptibility Test for Prevention of Bacterial Biofilms in Bone Tissue and on Implants.

Jensen LK, Bjarnsholt T, Kragh KN, Aalbæk B, Henriksen NL, Blirup SA, Pankoke K, Petersen A, Jensen HE.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01889-18. doi: 10.1128/AAC.01889-18. Print 2019 Feb.

PMID:
30455228
5.

[Interaction between microbiota and immune system in colorectal cancer].

Raskov H, Bjarnsholt T, Alamili M, Kragh KN, Gögenur I.

Ugeskr Laeger. 2018 Nov 5;180(45). pii: V04180253. Danish.

PMID:
30404713
6.

UV light assisted antibiotics for eradication of in vitro biofilms.

Argyraki A, Markvart M, Stavnsbjerg C, Kragh KN, Ou Y, Bjørndal L, Bjarnsholt T, Petersen PM.

Sci Rep. 2018 Nov 5;8(1):16360. doi: 10.1038/s41598-018-34340-8.

7.

In memoriam-Mark E. Shirtliff (1969-2018).

Coenye T, Bjarnsholt T, Stoodley P, Rumbaugh K.

Pathog Dis. 2018 Oct 1;76(7). doi: 10.1093/femspd/fty068. No abstract available.

PMID:
30247680
8.

Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis.

Raskov H, Kragh KN, Bjarnsholt T, Alamili M, Gögenur I.

Clin Transl Med. 2018 Sep 17;7(1):30. doi: 10.1186/s40169-018-0209-2.

9.

The use of fluorescent staining techniques for microscopic investigation of polymorphonuclear leukocytes and bacteria.

Alhede M, Stavnsbjerg C, Bjarnsholt T.

APMIS. 2018 Oct;126(10):779-794. doi: 10.1111/apm.12888. Epub 2018 Sep 6. Review.

PMID:
30191615
10.

Morphological evidence of biofilm in chronic obstructive sialadenitis.

Schrøder SA, Eickhardt S, Bjarnsholt T, Nørgaard T, Homøe P.

J Laryngol Otol. 2018 Jul;132(7):611-614. doi: 10.1017/S0022215118000646. Epub 2018 Jul 10.

PMID:
29986787
11.

Implants induce a new niche for microbiomes.

Jakobsen TH, Eickhardt SR, Gheorghe AG, Stenqvist C, Sønderholm M, Stavnsberg C, Jensen PØ, Odgaard A, Whiteley M, Moser C, Hvolris J, Hougen HP, Bjarnsholt T.

APMIS. 2018 Aug;126(8):685-692. doi: 10.1111/apm.12862. Epub 2018 Jul 2.

PMID:
29962006
12.

Biofilm formation - what we can learn from recent developments.

Bjarnsholt T, Buhlin K, Dufrêne YF, Gomelsky M, Moroni A, Ramstedt M, Rumbaugh KP, Schulte T, Sun L, Åkerlund B, Römling U.

J Intern Med. 2018 Oct;284(4):332-345. doi: 10.1111/joim.12782. Epub 2018 Jul 9.

13.

Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches.

Johani K, Fritz BG, Bjarnsholt T, Lipsky BA, Jensen SO, Yang M, Dean A, Hu H, Vickery K, Malone M.

Clin Microbiol Infect. 2019 Mar;25(3):332-339. doi: 10.1016/j.cmi.2018.04.036. Epub 2018 May 19.

PMID:
29787888
14.

Pseudomonas aeruginosa transcriptome during human infection.

Cornforth DM, Dees JL, Ibberson CB, Huse HK, Mathiesen IH, Kirketerp-Møller K, Wolcott RD, Rumbaugh KP, Bjarnsholt T, Whiteley M.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5125-E5134. doi: 10.1073/pnas.1717525115. Epub 2018 May 14.

15.

Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin.

Woetmann A, Alhede M, Dabelsteen S, Bjarnsholt T, Rybtke M, Nastasi C, Krejsgaard T, Andersen MH, Bonefeld CM, Geisler C, Givskov M, Odum N.

Oncotarget. 2018 Apr 13;9(28):19481-19489. doi: 10.18632/oncotarget.24603. eCollection 2018 Apr 13.

16.

Bacterial biofilms: a possible mechanism for chronic infection in patients with lumbar disc herniation - a prospective proof-of-concept study using fluorescence in situ hybridization.

Ohrt-Nissen S, Fritz BG, Walbom J, Kragh KN, Bjarnsholt T, Dahl B, Manniche C.

APMIS. 2018 May;126(5):440-447. doi: 10.1111/apm.12841.

PMID:
29696720
17.

Bacterial Aggregates Establish at the Edges of Acute Epidermal Wounds.

Bay L, Kragh KN, Eickhardt SR, Poulsen SS, Gjerdrum LMR, Ghathian K, Calum H, Ågren MS, Bjarnsholt T.

Adv Wound Care (New Rochelle). 2018 Apr 1;7(4):105-113. doi: 10.1089/wound.2017.0770.

18.

Combined Staining Techniques for Demonstration of Staphylococcus aureus Biofilm in Routine Histopathology.

Jensen LK, Henriksen NL, Bjarnsholt T, Kragh KN, Jensen HE.

J Bone Jt Infect. 2018 Feb 20;3(1):27-36. doi: 10.7150/jbji.22799. eCollection 2018.

19.

Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model.

Sønderholm M, Koren K, Wangpraseurt D, Jensen PØ, Kolpen M, Kragh KN, Bjarnsholt T, Kühl M.

NPJ Biofilms Microbiomes. 2018 Feb 19;4:3. doi: 10.1038/s41522-018-0047-4. eCollection 2018.

20.

Should standardized susceptibility testing for microbial biofilms be introduced in clinical practice?

Coenye T, Goeres D, Van Bambeke F, Bjarnsholt T.

Clin Microbiol Infect. 2018 Jun;24(6):570-572. doi: 10.1016/j.cmi.2018.01.003. Epub 2018 Jan 11. No abstract available.

PMID:
29337253
21.

The Inoculation Method Could Impact the Outcome of Microbiological Experiments.

Kragh KN, Alhede M, Rybtke M, Stavnsberg C, Jensen PØ, Tolker-Nielsen T, Whiteley M, Bjarnsholt T.

Appl Environ Microbiol. 2018 Feb 14;84(5). pii: e02264-17. doi: 10.1128/AEM.02264-17. Print 2018 Mar 1.

22.

The Consequences of Being in an Infectious Biofilm: Microenvironmental Conditions Governing Antibiotic Tolerance.

Sønderholm M, Bjarnsholt T, Alhede M, Kolpen M, Jensen PØ, Kühl M, Kragh KN.

Int J Mol Sci. 2017 Dec 12;18(12). pii: E2688. doi: 10.3390/ijms18122688. Review.

23.

Heading for centennial anniversary and beyond.

Norrild B, Ralfkiaer E, Bjarnsholt T, Jensen PØ.

APMIS. 2017 Dec;125(12):1133. doi: 10.1111/apm.12797. No abstract available.

PMID:
29193348
24.

Qualitative and Quantitative Determination of Quorum Sensing Inhibition In Vitro.

Jakobsen TH, Alhede M, Hultqvist LD, Bjarnsholt T, Givskov M.

Methods Mol Biol. 2018;1673:275-285. doi: 10.1007/978-1-4939-7309-5_21.

PMID:
29130180
25.

Imaging N-Acyl Homoserine Lactone Quorum Sensing In Vivo.

Hultqvist LD, Alhede M, Jakobsen TH, Givskov M, Bjarnsholt T.

Methods Mol Biol. 2018;1673:203-212. doi: 10.1007/978-1-4939-7309-5_16.

PMID:
29130175
26.

Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds.

Schultz G, Bjarnsholt T, James GA, Leaper DJ, McBain AJ, Malone M, Stoodley P, Swanson T, Tachi M, Wolcott RD; Global Wound Biofilm Expert Panel.

Wound Repair Regen. 2017 Sep;25(5):744-757. doi: 10.1111/wrr.12590. Epub 2017 Dec 12. Review.

PMID:
28960634
27.

Hyperbaric Oxygen Sensitizes Anoxic Pseudomonas aeruginosa Biofilm to Ciprofloxacin.

Kolpen M, Lerche CJ, Kragh KN, Sams T, Koren K, Jensen AS, Line L, Bjarnsholt T, Ciofu O, Moser C, Kühl M, Høiby N, Jensen PØ.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01024-17. doi: 10.1128/AAC.01024-17. Print 2017 Nov.

28.

Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls.

Ring HC, Thorsen J, Saunte DM, Lilje B, Bay L, Theut Riis P, Larsen N, O'Brien Andersen L, Vedel Nielsen H, Miller IM, Bjarnsholt T, Fuursted K, Jemec GB.

J Eur Acad Dermatol Venereol. 2018 Jan;32(1):125-128. doi: 10.1111/jdv.14538. Epub 2017 Sep 12.

PMID:
28833590
29.

Inactivation of Pseudomonas aeruginosa biofilm after ultraviolet light-emitting diode treatment: a comparative study between ultraviolet C and ultraviolet B.

Argyraki A, Markvart M, Bjørndal L, Bjarnsholt T, Petersen PM.

J Biomed Opt. 2017 Jun 1;22(6):65004. doi: 10.1117/1.JBO.22.6.065004.

PMID:
28655056
30.

The Pseudomonas aeruginosa PSL Polysaccharide Is a Social but Noncheatable Trait in Biofilms.

Irie Y, Roberts AEL, Kragh KN, Gordon VD, Hutchison J, Allen RJ, Melaugh G, Bjarnsholt T, West SA, Diggle SP.

MBio. 2017 Jun 20;8(3). pii: e00374-17. doi: 10.1128/mBio.00374-17.

31.

The Follicular Skin Microbiome in Patients With Hidradenitis Suppurativa and Healthy Controls.

Ring HC, Thorsen J, Saunte DM, Lilje B, Bay L, Riis PT, Larsen N, Andersen LO, Nielsen HV, Miller IM, Bjarnsholt T, Fuursted K, Jemec GB.

JAMA Dermatol. 2017 Sep 1;153(9):897-905. doi: 10.1001/jamadermatol.2017.0904.

32.

The occurrence of biofilm in an equine experimental wound model of healing by secondary intention.

Jørgensen E, Bay L, Bjarnsholt T, Bundgaard L, Sørensen MA, Jacobsen S.

Vet Microbiol. 2017 May;204:90-95. doi: 10.1016/j.vetmic.2017.03.011. Epub 2017 Mar 9.

PMID:
28532812
33.

Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

Jensen RG, Johansen HK, Bjarnsholt T, Eickhardt-Sørensen SR, Homøe P.

Eur Arch Otorhinolaryngol. 2017 Jul;274(7):2741-2747. doi: 10.1007/s00405-017-4586-8. Epub 2017 May 2.

PMID:
28466356
34.

Diagnosis of biofilm infections in cystic fibrosis patients.

Høiby N, Bjarnsholt T, Moser C, Jensen PØ, Kolpen M, Qvist T, Aanaes K, Pressler T, Skov M, Ciofu O.

APMIS. 2017 Apr;125(4):339-343. doi: 10.1111/apm.12689. Review.

PMID:
28407432
35.

Phage Inhibit Pathogen Dissemination by Targeting Bacterial Migrants in a Chronic Infection Model.

Darch SE, Kragh KN, Abbott EA, Bjarnsholt T, Bull JJ, Whiteley M.

MBio. 2017 Apr 4;8(2). pii: e00240-17. doi: 10.1128/mBio.00240-17.

36.

Comparison of two commercial broad-range PCR and sequencing assays for identification of bacteria in culture-negative clinical samples.

Stavnsbjerg C, Frimodt-Møller N, Moser C, Bjarnsholt T.

BMC Infect Dis. 2017 Mar 27;17(1):233. doi: 10.1186/s12879-017-2333-9.

38.

Pseudomonas aeruginosa Aggregate Formation in an Alginate Bead Model System Exhibits In Vivo-Like Characteristics.

Sønderholm M, Kragh KN, Koren K, Jakobsen TH, Darch SE, Alhede M, Jensen PØ, Whiteley M, Kühl M, Bjarnsholt T.

Appl Environ Microbiol. 2017 Apr 17;83(9). pii: e00113-17. doi: 10.1128/AEM.00113-17. Print 2017 May 1.

39.

The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data.

Malone M, Bjarnsholt T, McBain AJ, James GA, Stoodley P, Leaper D, Tachi M, Schultz G, Swanson T, Wolcott RD.

J Wound Care. 2017 Jan 2;26(1):20-25. doi: 10.12968/jowc.2017.26.1.20. Review.

PMID:
28103163
40.

Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response.

Jensen LK, Koch J, Dich-Jorgensen K, Aalbaek B, Petersen A, Fuursted K, Bjarnsholt T, Kragh KN, Tøtterup M, Bue M, Hanberg P, Søballe K, Heegaard PMH, Jensen HE.

J Orthop Res. 2017 Oct;35(10):2211-2221. doi: 10.1002/jor.23505. Epub 2017 Jan 15.

41.

Comparing culture and molecular methods for the identification of microorganisms involved in necrotizing soft tissue infections.

Rudkjøbing VB, Thomsen TR, Xu Y, Melton-Kreft R, Ahmed A, Eickhardt S, Bjarnsholt T, Poulsen SS, Nielsen PH, Earl JP, Ehrlich GD, Moser C.

BMC Infect Dis. 2016 Nov 8;16(1):652.

42.

Maxillary Sinus Impaction of a Core Carrier Causing Sustained Apical Periodontitis, Sinusitis, and Nasal Stenosis: A 3-year Follow-up.

Bjørndal L, Amaloo C, Markvart M, Rud V, Qvortrup K, Stavnsbjerg C, Bjarnsholt T.

J Endod. 2016 Dec;42(12):1851-1858. doi: 10.1016/j.joen.2016.07.027. Epub 2016 Oct 18.

PMID:
27769679
43.

Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir.

Jensen LK, Koch J, Aalbaek B, Moodley A, Bjarnsholt T, Kragh KN, Petersen A, Jensen HE.

APMIS. 2017 Jan;125(1):38-45. doi: 10.1111/apm.12597. Epub 2016 Oct 5.

44.

Achromobacter Species Isolated from Cystic Fibrosis Patients Reveal Distinctly Different Biofilm Morphotypes.

Nielsen SM, Nørskov-Lauritsen N, Bjarnsholt T, Meyer RL.

Microorganisms. 2016 Sep 14;4(3). pii: E33. doi: 10.3390/microorganisms4030033.

45.

Interspecific Bacterial Interactions are Reflected in Multispecies Biofilm Spatial Organization.

Liu W, Røder HL, Madsen JS, Bjarnsholt T, Sørensen SJ, Burmølle M.

Front Microbiol. 2016 Aug 31;7:1366. doi: 10.3389/fmicb.2016.01366. eCollection 2016. Review.

46.

Bacterial biofilm in chronic lesions of hidradenitis suppurativa.

Ring HC, Bay L, Nilsson M, Kallenbach K, Miller IM, Saunte DM, Bjarnsholt T, Tolker-Nielsen T, Jemec GB.

Br J Dermatol. 2017 Apr;176(4):993-1000. doi: 10.1111/bjd.15007. Epub 2017 Feb 19.

PMID:
27564400
47.

Incidence of Propionibacterium acnes in initially culture-negative thioglycollate broths-a prospective cohort study at a Danish University Hospital.

Kvich L, Jensen PØ, Justesen US, Bjarnsholt T.

Clin Microbiol Infect. 2016 Nov;22(11):941-945. doi: 10.1016/j.cmi.2016.07.036. Epub 2016 Aug 11.

48.

Editorial: The complexity of microbial biofilm research-an introduction to the third thematic issue on biofilms.

Coenye T, Bjarnsholt T.

Pathog Dis. 2016 Oct;74(7). pii: ftw053. doi: 10.1093/femspd/ftw053. Epub 2016 Jul 7. No abstract available.

PMID:
27402785
49.

Normal Skin Microbiota is Altered in Pre-clinical Hidradenitis Suppurativa.

Ring HC, Bay L, Kallenbach K, Miller IM, Prens E, Saunte DM, Bjarnsholt T, Jemec GB.

Acta Derm Venereol. 2017 Feb 8;97(2):208-213. doi: 10.2340/00015555-2503.

50.

Role of Multicellular Aggregates in Biofilm Formation.

Kragh KN, Hutchison JB, Melaugh G, Rodesney C, Roberts AE, Irie Y, Jensen PØ, Diggle SP, Allen RJ, Gordon V, Bjarnsholt T.

MBio. 2016 Mar 22;7(2):e00237. doi: 10.1128/mBio.00237-16.

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