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Items: 16

1.

Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma.

Munck Af Rosenschöld M, Johannesson P, Nikitidis A, Tyrchan C, Chang HF, Rönn R, Chapman D, Ullah V, Nikitidis G, Glader P, Käck H, Bonn B, Wågberg F, Björkstrand E, Andersson U, Swedin L, Rohman M, Andreasson T, Bergström EL, Jiang F, Zhou XH, Lundqvist AJ, Malmberg A, Ek M, Gordon E, Pettersen A, Ripa L, Davis AM.

J Med Chem. 2019 Sep 12;62(17):7769-7787. doi: 10.1021/acs.jmedchem.9b00555. Epub 2019 Aug 30.

PMID:
31415176
2.

Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy mice.

Sundbom M, Kaiser C, Björkstrand E, Castro VM, Larsson C, Selén G, Nyhem CS, James SR.

BMC Pharmacol. 2008 Feb 12;8:3. doi: 10.1186/1471-2210-8-3.

3.

Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione.

Liljebris C, Baranczewski P, Björkstrand E, Byström S, Lundgren B, Tjernberg A, Warolén M, James SR.

J Pharmacol Exp Ther. 2004 May;309(2):711-9. Epub 2004 Jan 27.

PMID:
14747616
4.

Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains.

Alberts P, Nilsson C, Selen G, Engblom LO, Edling NH, Norling S, Klingström G, Larsson C, Forsgren M, Ashkzari M, Nilsson CE, Fiedler M, Bergqvist E, Ohman B, Björkstrand E, Abrahmsen LB.

Endocrinology. 2003 Nov;144(11):4755-62. Epub 2003 Jul 31.

PMID:
12960099
5.

Dual effects of somatostatin analog octreotide on gastric emptying during and after intragastric fill.

Smedh U, Kaplan JM, Björkstrand E, Uvnäs-Moberg K.

Am J Physiol. 1999 Nov;277(5):R1291-6. doi: 10.1152/ajpregu.1999.277.5.R1291.

PMID:
10564199
6.

Endocrine and behavioral traits in low-avoidance Sprague-Dawley rats.

Uvnäs-Moberg K, Björkstrand E, Salmi P, Johansson C, Astrand M, Ahlenius S.

Regul Pept. 1999 Mar 17;80(1-2):75-82.

PMID:
10235637
7.

Postnatal oxytocin injections cause sustained weight gain and increased nociceptive thresholds in male and female rats.

Uvnäs-Moberg K, Alster P, Petersson M, Sohlström A, Björkstrand E.

Pediatr Res. 1998 Mar;43(3):344-8.

PMID:
9505272
8.

Evidence for a dual function of oxytocin in the control of growth hormone secretion in rats.

Björkstrand E, Hulting AL, Uvnäs-Moberg K.

Regul Pept. 1997 Mar 12;69(1):1-5.

PMID:
9163576
10.

Central oxytocin increases food intake and daily weight gain in rats.

Björkstrand E, Uvnäs-Moberg K.

Physiol Behav. 1996 Apr-May;59(4-5):947-52.

PMID:
8778892
11.

Evidence of a peripheral and a central effect of oxytocin on pancreatic hormone release in rats.

Björkstrand E, Eriksson M, Uvnäs-Moberg K.

Neuroendocrinology. 1996 Apr;63(4):377-83.

PMID:
8739893
12.

Role of vagal nerve activity during suckling. Effects on plasma levels of oxytocin, prolactin, VIP, somatostatin, insulin, glucagon, glucose and of milk secretion in lactating rats.

Eriksson M, Björkstrand E, Smedh U, Alster P, Matthiesen AS, Uvnäs-Moberg K.

Acta Physiol Scand. 1994 Aug;151(4):453-9.

PMID:
7976418
13.

Oxytocin modulates the effects of galanin in carrageenan-induced hyperalgesia in rats.

Lundeberg T, Meister B, Björkstrand E, Uvnäs-Moberg K.

Brain Res. 1993 Apr 16;608(2):181-5.

PMID:
7684311
14.

Effect of galanin on plasma levels of oxytocin and cholecystokinin.

Björkstrand E, Hulting AL, Meister B, Uvnäs-Moberg K.

Neuroreport. 1993 Jan;4(1):10-2.

PMID:
7680910
15.

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