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Full-length RNA-seq from single cells using Smart-seq2. Picelli S et al. Nat Protoc. (2014)

Smart-seq2 for sensitive full-length transcriptome profiling in single cells. Picelli S et al. Nat Methods. (2013)

Dopamine neuron systems in the brain: an update. Björklund A et al. Trends Neurosci. (2007)

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Items: 1 to 50 of 781


Reduced Risk of Sinusoidal Obstruction Syndrome of the Liver after Busulfan-Cyclophosphamide Conditioning Prior to Allogeneic Hematopoietic Stem Cell Transplantation.

El-Serafi I, Remberger M, Ringdèn O, Törlén J, Sundin M, Björklund A, Winiarski J, Mattsson J.

Clin Transl Sci. 2019 Nov 1. doi: 10.1111/cts.12709. [Epub ahead of print]


Mental fatigue after allogeneic hematopoietic stem cell transplantation is associated with cognitive dysfunction, but not central nervous system inflammation.

Boberg E, Kadri N, Winterling J, Davies LC, Björklund A, Msghina M, Iacobaeus E, Le Blanc K.

Haematologica. 2019 Oct 24. pii: haematol.2019.225326. doi: 10.3324/haematol.2019.225326. [Epub ahead of print]


hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease.

Adler AF, Cardoso T, Nolbrant S, Mattsson B, Hoban DB, Jarl U, Wahlestedt JN, Grealish S, Björklund A, Parmar M.

Cell Rep. 2019 Sep 24;28(13):3462-3473.e5. doi: 10.1016/j.celrep.2019.08.058.


Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease.

Rosenblad C, Li Q, Pioli EY, Dovero S, Antunes AS, Agúndez L, Bardelli M, Linden RM, Henckaerts E, Björklund A, Bezard E, Björklund T.

Brain. 2019 Aug 1;142(8):2402-2416. doi: 10.1093/brain/awz176.


Investigating optimal β-cell-preserving treatment in latent autoimmune diabetes in adults: Results from a 21-month randomized trial.

Hals IK, Fiskvik Fleiner H, Reimers N, Astor MC, Filipsson K, Ma Z, Grill V, Björklund A.

Diabetes Obes Metab. 2019 Oct;21(10):2219-2227. doi: 10.1111/dom.13797. Epub 2019 Jun 19.


Diagnosis of Systemic Capillary Leak Syndrome in a Young Child Treated with Intravenous Immunoglobulin in the Acute Phase.

Asmundsson ASE, Bjorklund AR, Fisher GA.

J Pediatr Intensive Care. 2018 Jun;7(2):94-96. doi: 10.1055/s-0037-1607342. Epub 2017 Oct 23.


Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing.

Hård J, Al Hakim E, Kindblom M, Björklund ÅK, Sennblad B, Demirci I, Paterlini M, Reu P, Borgström E, Ståhl PL, Michaelsson J, Mold JE, Frisén J.

Genome Biol. 2019 Apr 1;20(1):68. doi: 10.1186/s13059-019-1673-8.


Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells.

Ma Z, Ketelhuth DFJ, Wirström T, Ohki T, Forteza MJ, Wang H, Grill V, Wollheim CB, Björklund A.

J Mol Endocrinol. 2019 May 1;62(4):159-168. doi: 10.1530/JME-18-0146.


Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development.

Tiklová K, Björklund ÅK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmström F, Joodmardi E, Nilsson M, Parmar M, Perlmann T.

Nat Commun. 2019 Feb 4;10(1):581. doi: 10.1038/s41467-019-08453-1.


Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing.

Bartoschek M, Oskolkov N, Bocci M, Lövrot J, Larsson C, Sommarin M, Madsen CD, Lindgren D, Pekar G, Karlsson G, Ringnér M, Bergh J, Björklund Å, Pietras K.

Nat Commun. 2018 Dec 4;9(1):5150. doi: 10.1038/s41467-018-07582-3.


The Use of Occupational Adaptation in Research: A Scoping Review.

Johansson A, Fristedt S, Boström M, Björklund A.

Occup Ther Health Care. 2018 Oct;32(4):422-439. doi: 10.1080/07380577.2018.1526433. Epub 2018 Nov 22.


Author Correction: A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons.

Södersten E, Toskas K, Rraklli V, Tiklova K, Björklund ÅK, Ringnér M, Perlmann T, Holmberg J.

Nat Commun. 2018 Nov 2;9(1):4639. doi: 10.1038/s41467-018-07154-5.


Sequentially acting SOX proteins orchestrate astrocyte- and oligodendrocyte-specific gene expression.

Klum S, Zaouter C, Alekseenko Z, Björklund ÅK, Hagey DW, Ericson J, Muhr J, Bergsland M.

EMBO Rep. 2018 Nov;19(11). pii: e46635. doi: 10.15252/embr.201846635. Epub 2018 Aug 30.


Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment.

Dyczynski M, Vesterlund M, Björklund AC, Zachariadis V, Janssen J, Gallart-Ayala H, Daskalaki E, Wheelock CE, Lehtiö J, Grandér D, Tamm KP, Nilsson R.

Cell Death Dis. 2018 Aug 28;9(9):846. doi: 10.1038/s41419-018-0625-7.


Exploring parasite heterogeneity using single-cell RNA-seq reveals a gene signature among sexual stage Plasmodium falciparum parasites.

Ngara M, Palmkvist M, Sagasser S, Hjelmqvist D, Björklund ÅK, Wahlgren M, Ankarklev J, Sandberg R.

Exp Cell Res. 2018 Oct 1;371(1):130-138. doi: 10.1016/j.yexcr.2018.08.003. Epub 2018 Aug 8.


Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development.

Marques S, van Bruggen D, Vanichkina DP, Floriddia EM, Munguba H, Väremo L, Giacomello S, Falcão AM, Meijer M, Björklund ÅK, Hjerling-Leffler J, Taft RJ, Castelo-Branco G.

Dev Cell. 2018 Aug 20;46(4):504-517.e7. doi: 10.1016/j.devcel.2018.07.005. Epub 2018 Aug 2.


Adulthood transitions in health and welfare; a literature review.

Munck B, Björklund A, Jansson I, Lundberg K, Wagman P.

Nurs Open. 2018 Mar 6;5(3):254-260. doi: 10.1002/nop2.136. eCollection 2018 Jul. Review.


Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson's disease.

Faustini G, Longhena F, Varanita T, Bubacco L, Pizzi M, Missale C, Benfenati F, Björklund A, Spano P, Bellucci A.

Acta Neuropathol. 2018 Oct;136(4):621-639. doi: 10.1007/s00401-018-1892-1. Epub 2018 Jul 25.


Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats.

Cardoso T, Adler AF, Mattsson B, Hoban DB, Nolbrant S, Wahlestedt JN, Kirkeby A, Grealish S, Björklund A, Parmar M.

J Comp Neurol. 2018 Sep 1;526(13):2133-2146. doi: 10.1002/cne.24500. Epub 2018 Jul 31.


Use of a modified bubble continuous positive airway pressure (bCPAP) device for children in respiratory distress in low- and middle-income countries: a safety study.

Bjorklund AR, Odongkara Mpora B, Steiner ME, Fischer G, Davey CS, Slusher TM.

Paediatr Int Child Health. 2019 Aug;39(3):160-167. doi: 10.1080/20469047.2018.1474698. Epub 2018 Jun 18.


Hallmarks in prostate cancer imaging with Ga68-PSMA-11-PET/CT with reference to detection limits and quantitative properties.

Sanchez-Crespo A, Jussing E, Björklund AC, Pokrovskaja Tamm K.

EJNMMI Res. 2018 Apr 4;8(1):27. doi: 10.1186/s13550-018-0378-4.


Pediatric Critical Care in Resource-Limited Settings-Overview and Lessons Learned.

Slusher TM, Kiragu AW, Day LT, Bjorklund AR, Shirk A, Johannsen C, Hagen SA.

Front Pediatr. 2018 Mar 16;6:49. doi: 10.3389/fped.2018.00049. eCollection 2018. Review.


A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons.

Södersten E, Toskas K, Rraklli V, Tiklova K, Björklund ÅK, Ringnér M, Perlmann T, Holmberg J.

Nat Commun. 2018 Mar 26;9(1):1226. doi: 10.1038/s41467-018-03538-9. Erratum in: Nat Commun. 2018 Nov 2;9(1):4639.


Change of apheresis device decreased the incidence of severe acute graft-versus-host disease among patients after allogeneic stem cell transplantation with sibling donors.

Wang T, Remberger M, Axdorph Nygell U, Sundin M, Björklund A, Mattsson J, Uhlin M, Watz E.

Transfusion. 2018 Jun;58(6):1442-1451. doi: 10.1111/trf.14579. Epub 2018 Mar 13.


Innovative Chemical Process for Recycling Thermosets Cured with Recyclamines® by Converting Bio-Epoxy Composites in Reusable Thermoplastic-An LCA Study.

La Rosa AD, Blanco I, Banatao DR, Pastine SJ, Björklund A, Cicala G.

Materials (Basel). 2018 Feb 28;11(3). pii: E353. doi: 10.3390/ma11030353.


The serotonergic system in L-DOPA-induced dyskinesia: pre-clinical evidence and clinical perspective.

Carta M, Björklund A.

J Neural Transm (Vienna). 2018 Aug;125(8):1195-1202. doi: 10.1007/s00702-018-1865-5. Epub 2018 Feb 26. Review.


Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML.

Björklund AT, Carlsten M, Sohlberg E, Liu LL, Clancy T, Karimi M, Cooley S, Miller JS, Klimkowska M, Schaffer M, Watz E, Wikström K, Blomberg P, Wahlin BE, Palma M, Hansson L, Ljungman P, Hellström-Lindberg E, Ljunggren HG, Malmberg KJ.

Clin Cancer Res. 2018 Apr 15;24(8):1834-1844. doi: 10.1158/1078-0432.CCR-17-3196. Epub 2018 Feb 14.


Prostaglandin E2 suppresses human group 2 innate lymphoid cell function.

Maric J, Ravindran A, Mazzurana L, Björklund ÅK, Van Acker A, Rao A, Friberg D, Dahlén SE, Heinemann A, Konya V, Mjösberg J.

J Allergy Clin Immunol. 2018 May;141(5):1761-1773.e6. doi: 10.1016/j.jaci.2017.09.050. Epub 2017 Dec 5.


A TRPM4 Inhibitor 9-Phenanthrol Inhibits Glucose- and Glucagon-Like Peptide 1-Induced Insulin Secretion from Rat Islets of Langerhans.

Ma Z, Björklund A, Islam MS.

J Diabetes Res. 2017;2017:5131785. doi: 10.1155/2017/5131785. Epub 2017 Oct 2.


Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates.

Hals I, Ohki T, Singh R, Ma Z, Björklund A, Balasuriya C, Scholz H, Grill V.

Physiol Rep. 2017 Oct;5(19). pii: e13447. doi: 10.14814/phy2.13447. Epub 2017 Oct 16.


Modeling Parkinson's disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain.

Thakur P, Breger LS, Lundblad M, Wan OW, Mattsson B, Luk KC, Lee VMY, Trojanowski JQ, Björklund A.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8284-E8293. doi: 10.1073/pnas.1710442114. Epub 2017 Sep 12.


Natural killer cell-mediated immunosurveillance of human cancer.

Malmberg KJ, Carlsten M, Björklund A, Sohlberg E, Bryceson YT, Ljunggren HG.

Semin Immunol. 2017 Jun;31:20-29. doi: 10.1016/j.smim.2017.08.002. Epub 2017 Sep 6. Review.


Toxicological effects of fludarabine and treosulfan conditioning before allogeneic stem-cell transplantation.

Remberger M, Törlen J, Serafi IE, Garming-Legert K, Björklund A, Ljungman P, Sundin M, Hassan M, Mattsson J.

Int J Hematol. 2017 Oct;106(4):471-475. doi: 10.1007/s12185-017-2320-3. Epub 2017 Aug 28.


BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to l-DOPA-induced dyskinesia in 6-OHDA-lesioned rats.

Tronci E, Napolitano F, Muñoz A, Fidalgo C, Rossi F, Björklund A, Usiello A, Carta M.

Exp Neurol. 2017 Nov;297:73-81. doi: 10.1016/j.expneurol.2017.07.017. Epub 2017 Jul 27.


RNAi prodrugs targeting Plk1 induce specific gene silencing in primary cells from pediatric T-acute lymphoblastic leukemia patients.

Kolosenko I, Edsbäcker E, Björklund AC, Hamil AS, Goroshchuk O, Grandér D, Dowdy SF, Palm-Apergi C.

J Control Release. 2017 Sep 10;261:199-206. doi: 10.1016/j.jconrel.2017.07.002. Epub 2017 Jul 3.


Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease.

Stikvoort A, Chen Y, Rådestad E, Törlén J, Lakshmikanth T, Björklund A, Mikes J, Achour A, Gertow J, Sundberg B, Remberger M, Sundin M, Mattsson J, Brodin P, Uhlin M.

Front Immunol. 2017 Jun 19;8:717. doi: 10.3389/fimmu.2017.00717. eCollection 2017.


Considerations in Caring for Adult Patients in the Pediatric Intensive Care Unit.

Needle JS, Bjorklund A, Gupta S.

J Pediatr Intensive Care. 2017 Jun;6(2):77-82. doi: 10.1055/s-0036-1584680. Epub 2016 Jun 24. Review.



Dunnett S, Björklund A.

Prog Brain Res. 2017;231:xxv-xxvii. doi: 10.1016/S0079-6123(17)30030-4. No abstract available.



Dunnett S, Björklund A.

Prog Brain Res. 2017;230:xxv-xxvii. doi: 10.1016/S0079-6123(17)30042-0. No abstract available.


Mechanisms and use of neural transplants for brain repair.

Dunnett SB, Björklund A.

Prog Brain Res. 2017;230:1-51. doi: 10.1016/bs.pbr.2016.11.002. Epub 2017 Apr 14.


Replacing Dopamine Neurons in Parkinson's Disease: How did it happen?

Björklund A, Lindvall O.

J Parkinsons Dis. 2017;7(s1):S21-S31. doi: 10.3233/JPD-179002.


The Assessment, Evaluation, and Management of the Critically Ill Child in Resource-Limited International Settings.

Slusher T, Bjorklund A, Aanyu HT, Kiragu A, Philip C.

J Pediatr Intensive Care. 2017 Mar;6(1):66-76. doi: 10.1055/s-0036-1584677. Epub 2016 Jun 29. Review.


Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates.

Shikhagaie MM, Björklund ÅK, Mjösberg J, Erjefält JS, Cornelissen AS, Ros XR, Bal SM, Koning JJ, Mebius RE, Mori M, Bruchard M, Blom B, Spits H.

Cell Rep. 2017 Feb 14;18(7):1761-1773. doi: 10.1016/j.celrep.2017.01.063.


Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages.

Kee N, Volakakis N, Kirkeby A, Dahl L, Storvall H, Nolbrant S, Lahti L, Björklund ÅK, Gillberg L, Joodmardi E, Sandberg R, Parmar M, Perlmann T.

Cell Stem Cell. 2017 Jan 5;20(1):29-40. doi: 10.1016/j.stem.2016.10.003. Epub 2016 Oct 27.


High incidence of severe chronic GvHD after HSCT with sibling donors. A single center analysis.

Remberger M, Afram G, Sundin M, Uhlin M, LeBlanc K, Björklund A, Mattsson J, Ljungman P.

Bone Marrow Transplant. 2016 Nov;51(11):1518-1521. doi: 10.1038/bmt.2016.159. Epub 2016 Jun 6. No abstract available.


Culture at low glucose up-regulates mitochondrial function in pancreatic β cells with accompanying effects on viability.

Hals IK, Singh R, Ma Z, Scholz H, Björklund A, Grill V.

Islets. 2016 Nov;8(6):165-176. Epub 2016 Oct 20.


Art therapy for patients with depression: expert opinions on its main aspects for clinical practice.

Blomdahl C, Gunnarsson BA, Guregård S, Rusner M, Wijk H, Björklund A.

J Ment Health. 2016 Dec;25(6):527-535. Epub 2016 Jul 28.


α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter.

Wan OW, Shin E, Mattsson B, Caudal D, Svenningsson P, Björklund A.

Sci Rep. 2016 May 23;6:26285. doi: 10.1038/srep26285.


A Delphi study of occurring information in housing adaptation certificates.

Westlin E, Björklund A.

Scand J Occup Ther. 2016 Sep;23(5):357-65. doi: 10.1080/11038128.2016.1177591. Epub 2016 May 4.


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