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Items: 20


Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children.

Cuthbertson L, Oo SWC, Cox MJ, Khoo SK, Cox DW, Chidlow G, Franks K, Prastanti F, Borland ML, Gern JE, Smith DW, Bizzintino JA, Laing IA, Le Souëf PN, Moffatt MF, Cookson WOC.

PLoS One. 2019 Oct 17;14(10):e0223990. doi: 10.1371/journal.pone.0223990. eCollection 2019.


Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing.

Khoo SK, Read J, Franks K, Zhang G, Bizzintino J, Coleman L, McCrae C, Öberg L, Troy NM, Prastanti F, Everard J, Oo S, Borland ML, Maciewicz RA, Le Souëf PN, Laing IA, Bosco A.

J Immunol. 2019 Mar 15;202(6):1845-1858. doi: 10.4049/jimmunol.1800178. Epub 2019 Feb 11.


Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions.

Cox DW, Khoo SK, Zhang G, Lindsay K, Keil AD, Knight G, Gern JE, Laing IA, Bizzintino J, Le Souëf PN.

Eur Respir J. 2018 Aug 9;52(2). pii: 1800207. doi: 10.1183/13993003.00207-2018. Print 2018 Aug. No abstract available.


Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco.

Annamalay AA, Jroundi I, Bizzintino J, Khoo SK, Zhang G, Lehmann D, Laing IA, Gern J, Goldblatt J, Mahraoui C, Benmessaoud R, Moraleda C, Bassat Q, Le Souëf P.

J Med Virol. 2017 Apr;89(4):582-588. doi: 10.1002/jmv.24684. Epub 2016 Sep 30.


Rhinovirus species and clinical features in children hospitalised with pneumonia from Mozambique.

Annamalay AA, Lanaspa M, Khoo SK, Madrid L, Acácio S, Zhang G, Laing IA, Gern J, Goldblatt J, Bizzintino J, Lehmann D, Le Souëf PN, Bassat Q.

Trop Med Int Health. 2016 Sep;21(9):1171-80. doi: 10.1111/tmi.12743. Epub 2016 Jul 26.


Respiratory viruses in young South African children with acute lower respiratory infections and interactions with HIV.

Annamalay AA, Abbott S, Sikazwe C, Khoo SK, Bizzintino J, Zhang G, Laing I, Chidlow GR, Smith DW, Gern J, Goldblatt J, Lehmann D, Green RJ, Le Souëf PN.

J Clin Virol. 2016 Aug;81:58-63. doi: 10.1016/j.jcv.2016.06.002. Epub 2016 Jun 4.


Recurrent rhinovirus detections in children following a rhinovirus-induced wheezing exacerbation: A retrospective study.

Halmø Hürdum S, Zhang G, Khoo SK, Bizzintino J, Franks KM, Lindsay K, Keil AD, Cox DW, Goldblatt J, Bochkov YA, Gern J, Ulrik CS, Souëf PN, Laing IA.

Int J Pediatr Child Health. 2015 Aug;3(1):10-18. doi: 10.12974/2311-8687.2015.03.01.2.


Lower anti-echovirus antibody responses in children presenting to hospital with asthma exacerbations.

Iwasaki J, Chai LY, Khoo SK, Bizzintino J, Laing IA, Le Souëf PN, Thomas WR, Hales BJ.

Clin Exp Allergy. 2015 Oct;45(10):1523-30. doi: 10.1111/cea.12501.


Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection.

Iwasaki J, Smith WA, Khoo SK, Bizzintino J, Zhang G, Cox DW, Laing IA, Le Souëf PN, Thomas WR, Hales BJ.

J Allergy Clin Immunol. 2014 Jul;134(1):25-32. doi: 10.1016/j.jaci.2014.03.014. Epub 2014 Apr 24.


Human rhinovirus species C infection in young children with acute wheeze is associated with increased acute respiratory hospital admissions.

Cox DW, Bizzintino J, Ferrari G, Khoo SK, Zhang G, Whelan S, Lee WM, Bochkov YA, Geelhoed GC, Goldblatt J, Gern JE, Laing IA, Le Souëf PN.

Am J Respir Crit Care Med. 2013 Dec 1;188(11):1358-64. doi: 10.1164/rccm.201303-0498OC.


Prevalence of and risk factors for human rhinovirus infection in healthy aboriginal and non-aboriginal Western Australian children.

Annamalay AA, Khoo SK, Jacoby P, Bizzintino J, Zhang G, Chidlow G, Lee WM, Moore HC, Harnett GB, Smith DW, Gern JE, LeSouef PN, Laing IA, Lehmann D; Kalgoorlie Otitis Media Research Project Team.

Pediatr Infect Dis J. 2012 Jul;31(7):673-9. doi: 10.1097/INF.0b013e318256ffc6.


Symptomatic viral infection is associated with impaired response to treatment in children with acute asthma.

Rueter K, Bizzintino J, Martin AC, Zhang G, Hayden CM, Geelhoed GC, Goldblatt J, Laing IA, Le Souëf PN.

J Pediatr. 2012 Jan;160(1):82-7. doi: 10.1016/j.jpeds.2011.06.025. Epub 2011 Aug 19.


The role of GSTP1 polymorphisms and tobacco smoke exposure in children with acute asthma.

Schultz EN, Devadason SG, Khoo SK, Zhang G, Bizzintino JA, Martin AC, Goldblatt J, Laing IA, Le Souëf PN, Hayden CM.

J Asthma. 2010 Nov;47(9):1049-56. doi: 10.1080/02770903.2010.508856.


Association between human rhinovirus C and severity of acute asthma in children.

Bizzintino J, Lee WM, Laing IA, Vang F, Pappas T, Zhang G, Martin AC, Khoo SK, Cox DW, Geelhoed GC, McMinn PC, Goldblatt J, Gern JE, Le Souëf PN.

Eur Respir J. 2011 May;37(5):1037-42. doi: 10.1183/09031936.00092410. Epub 2010 Aug 6.


The importance of environment on respiratory genotype/phenotype relationships in the Inuit.

Candelaria PV, Backer V, Khoo SK, Bizzintino JA, Hayden CM, Baynam G, Laing IA, Zhang G, Porsbjerg C, Goldblatt J, Le Souëf PN; Greenlandic Study Population Group.

Allergy. 2010 Feb;65(2):229-37. doi: 10.1111/j.1398-9995.2009.02145.x. Epub 2009 Oct 1.


Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children.

Subrata LS, Bizzintino J, Mamessier E, Bosco A, McKenna KL, Wikström ME, Goldblatt J, Sly PD, Hales BJ, Thomas WR, Laing IA, LeSouëf PN, Holt PG.

J Immunol. 2009 Aug 15;183(4):2793-800. doi: 10.4049/jimmunol.0900695. Epub 2009 Jul 20.


Leukotriene pathway polymorphisms are associated with altered cysteinyl leukotriene production in children with acute asthma.

Bizzintino JA, Khoo SK, Zhang G, Martin AC, Rueter K, Geelhoed GC, Goldblatt J, Laing IA, Le Souëf PN, Hayden CM.

Prostaglandins Leukot Essent Fatty Acids. 2009 Jul;81(1):9-15. doi: 10.1016/j.plefa.2009.05.022. Epub 2009 Jun 12.


Anti-bacterial IgE in the antibody responses of house dust mite allergic children convalescent from asthma exacerbation.

Hales BJ, Martin AC, Pearce LJ, Rueter K, Zhang G, Khoo SK, Hayden CM, Bizzintino J, McMinn P, Geelhoed GC, Lee WM, Goldblatt J, Laing IA, LeSouëf PN, Thomas WR.

Clin Exp Allergy. 2009 Aug;39(8):1170-8. doi: 10.1111/j.1365-2222.2009.03252.x. Epub 2009 Apr 17.


Investigations into the role of ST2 in acute asthma in children.

Ali M, Zhang G, Thomas WR, McLean CJ, Bizzintino JA, Laing IA, Martin AC, Goldblatt J, Le Souëf PN, Hayden CM.

Tissue Antigens. 2009 Mar;73(3):206-12. doi: 10.1111/j.1399-0039.2008.01185.x.


Beta2-adrenoceptor polymorphisms predict response to beta2-agonists in children with acute asthma.

Martin AC, Zhang G, Rueter K, Khoo SK, Bizzintino J, Hayden CM, Geelhoed GC, Goldblatt J, Laing IA, Le Souëf PN.

J Asthma. 2008 Jun;45(5):383-8. doi: 10.1080/02770900801971792.


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