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Items: 1 to 50 of 212

1.

β-Caryophyllene Mitigates Collagen Antibody Induced Arthritis (CAIA) in Mice Through a Cross-Talk between CB2 and PPAR-γ Receptors.

Irrera N, D'Ascola A, Pallio G, Bitto A, Mazzon E, Mannino F, Squadrito V, Arcoraci V, Minutoli L, Campo GM, Avenoso A, Bongiorno EB, Vaccaro M, Squadrito F, Altavilla D.

Biomolecules. 2019 Jul 31;9(8). pii: E326. doi: 10.3390/biom9080326.

2.

Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells.

Ettari R, Pallio G, Pizzino G, Irrera N, Zappalà M, Maiorana S, Di Chio C, Altavilla D, Squadrito F, Bitto A.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1307-1313. doi: 10.1080/14756366.2019.1594802.

PMID:
31307247
3.

Increased pain and inflammatory sensitivity in growth hormone-releasing hormone (GHRH) knockout mice.

Leone S, Chiavaroli A, Recinella L, Orlando G, Ferrante C, Marconi GD, Gasparo I, Bitto A, Salvatori R, Brunetti L.

Prostaglandins Other Lipid Mediat. 2019 Jul 10;144:106362. doi: 10.1016/j.prostaglandins.2019.106362. [Epub ahead of print]

PMID:
31301405
4.

Development of Novel Amides as Noncovalent Inhibitors of Immunoproteasomes.

Ettari R, Cerchia C, Maiorana S, Guccione M, Novellino E, Bitto A, Grasso S, Lavecchia A, Zappalà M.

ChemMedChem. 2019 Apr 17;14(8):842-852. doi: 10.1002/cmdc.201900028. Epub 2019 Mar 26.

PMID:
30829448
5.

Medical simulation in pharmacology learning and retention: A comparison study with traditional teaching in undergraduate medical students.

Arcoraci V, Squadrito F, Altavilla D, Bitto A, Minutoli L, Penna O, Amato A, Bruno R, Tripodi VF, Alibrandi A, Ingrassia PL, Santalucia P, Fodale V.

Pharmacol Res Perspect. 2019 Jan 9;7(1):e00449. doi: 10.1002/prp2.449. eCollection 2019 Feb.

6.

mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases.

Johnson SC, Martinez F, Bitto A, Gonzalez B, Tazaerslan C, Cohen C, Delaval L, Timsit J, Knebelmann B, Terzi F, Mahal T, Zhu Y, Morgan PG, Sedensky MM, Kaeberlein M, Legendre C, Suh Y, Canaud G.

Kidney Int. 2019 Feb;95(2):455-466. doi: 10.1016/j.kint.2018.08.038. Epub 2018 Nov 22.

PMID:
30471880
7.

Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity.

Marini HR, Puzzolo D, Micali A, Adamo EB, Irrera N, Pisani A, Pallio G, Trichilo V, Malta C, Bitto A, Squadrito F, Altavilla D, Minutoli L.

Oxid Med Cell Longev. 2018 Aug 29;2018:4285694. doi: 10.1155/2018/4285694. eCollection 2018. Erratum in: Oxid Med Cell Longev. 2018 Dec 13;2018:9176012.

8.

Activation of A2A Receptor by PDRN Reduces Neuronal Damage and Stimulates WNT/β-CATENIN Driven Neurogenesis in Spinal Cord Injury.

Irrera N, Arcoraci V, Mannino F, Vermiglio G, Pallio G, Minutoli L, Bagnato G, Anastasi GP, Mazzon E, Bramanti P, Squadrito F, Altavilla D, Bitto A.

Front Pharmacol. 2018 May 29;9:506. doi: 10.3389/fphar.2018.00506. eCollection 2018.

9.

Cadmium-Induced Oxidative Stress Impairs Glycemic Control in Adolescents.

Pizzino G, Irrera N, Bitto A, Pallio G, Mannino F, Arcoraci V, Aliquò F, Minutoli L, De Ponte C, D'andrea P, Squadrito F, Altavilla D.

Oxid Med Cell Longev. 2017;2017:6341671. doi: 10.1155/2017/6341671. Epub 2017 Dec 12.

10.

Vitamin D Status and the Relationship with Bone Fragility Fractures in HIV-Infected Patients: A Case Control Study.

Atteritano M, Mirarchi L, Venanzi-Rullo E, Santoro D, Iaria C, Catalano A, Lasco A, Arcoraci V, Lo Gullo A, Bitto A, Squadrito F, Cascio A.

Int J Mol Sci. 2018 Jan 2;19(1). pii: E119. doi: 10.3390/ijms19010119.

11.

Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors.

Maccari R, Ettari R, Adornato I, Naß A, Wolber G, Bitto A, Mannino F, Aliquò F, Bruno G, Nicolò F, Previti S, Grasso S, Zappalà M, Ottanà R.

Bioorg Med Chem Lett. 2018 Feb 1;28(3):278-283. doi: 10.1016/j.bmcl.2017.12.053. Epub 2017 Dec 26.

PMID:
29292224
12.

Corrigendum: Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.

Ito TK, Lu C, Khan J, Nguyen Q, Huang HZ, Kim D, Phillips JJ, Tan J, Lee Y, Nguyen T, Khessib S, Lim N, Mekvanich S, Oh J, Pineda VV, Wang W, Bitto A, An JY, Morton JF, Setou M, Ladiges WC, Kaeberlein M.

Front Genet. 2017 Dec 22;8:221. doi: 10.3389/fgene.2017.00221. eCollection 2017.

13.

Dual αvβ3 and αvβ5 blockade attenuates fibrotic and vascular alterations in a murine model of systemic sclerosis.

Bagnato GL, Irrera N, Pizzino G, Santoro D, Roberts WN, Bagnato G, Pallio G, Vaccaro M, Squadrito F, Saitta A, Altavilla D, Bitto A.

Clin Sci (Lond). 2018 Jan 19;132(2):231-242. doi: 10.1042/CS20171426. Print 2018 Jan 31.

PMID:
29237724
14.

Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetes.

Bitto A, Irrera N, Pizzino G, Pallio G, Mannino F, Vaccaro M, Arcoraci V, Aliquò F, Minutoli L, Colonna MR, Galeano MR, Brines M, De Ponte C, Collino M, Squadrito F, Altavilla D.

Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):632-639. doi: 10.1016/j.bbadis.2017.12.006. Epub 2017 Dec 7.

15.

Effects of the antagomiRs 15b and 200b on the altered healing pattern of diabetic mice.

Pizzino G, Irrera N, Galfo F, Pallio G, Mannino F, D'amore A, Pellegrino E, Ieni A, Russo GT, Calapai M, Altavilla D, Squadrito F, Bitto A.

Br J Pharmacol. 2018 Feb;175(4):644-655. doi: 10.1111/bph.14113. Epub 2018 Jan 18.

16.

Impairment of elastic properties of the aorta in bicuspid aortic valve: relationship between biomolecular and aortic strain patterns.

Longobardo L, Carerj ML, Pizzino G, Bitto A, Piccione MC, Zucco M, Oreto L, Todaro MC, Calabrò MP, Squadrito F, Di Bella G, Oreto G, Khandheria BK, Carerj S, Zito C.

Eur Heart J Cardiovasc Imaging. 2018 Aug 1;19(8):879-887. doi: 10.1093/ehjci/jex224.

PMID:
29029085
17.

Flavocoxid exerts a potent antiviral effect against hepatitis B virus.

Pollicino T, Musolino C, Irrera N, Bitto A, Lombardo D, Timmoneri M, Minutoli L, Raimondo G, Squadrito G, Squadrito F, Altavilla D.

Inflamm Res. 2018 Jan;67(1):89-103. doi: 10.1007/s00011-017-1099-2. Epub 2017 Oct 10.

PMID:
29018874
18.

Adenosine Receptor Stimulation Improves Glucocorticoid-Induced Osteoporosis in a Rat Model.

Pizzino G, Irrera N, Galfo F, Oteri G, Atteritano M, Pallio G, Mannino F, D'Amore A, Pellegrino E, Aliquò F, Anastasi GP, Cutroneo G, Squadrito F, Altavilla D, Bitto A.

Front Pharmacol. 2017 Sep 5;8:558. doi: 10.3389/fphar.2017.00558. eCollection 2017.

19.

Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency.

Ito TK, Lu C, Khan J, Nguyen Q, Huang HZ, Kim D, Phillips J, Tan J, Lee Y, Nguyen T, Khessib S, Lim N, Mekvanich S, Oh J, Pineda VV, Wang W, Bitto A, An JY, Morton JF, Setou M, Ladiges WC, Kaeberlein M.

Front Genet. 2017 Sep 1;8:113. doi: 10.3389/fgene.2017.00113. eCollection 2017. Erratum in: Front Genet. 2017 Dec 22;8:221.

20.

Evidence for using a dual COX 1/2 and 5-LOX inhibitor in neurodegenerative diseases.

Irrera N, Bitto A.

Neural Regen Res. 2017 Jul;12(7):1077-1078. doi: 10.4103/1673-5374.211185. No abstract available.

21.

HDL subclasses and the common CETP TaqIB variant predict the incidence of microangiopatic complications in type 2 diabetic women: A 9years follow-up study.

Russo GT, Giandalia A, Romeo EL, Muscianisi M, Ruffo MC, Alibrandi A, Bitto A, Forte F, Grillone A, Asztalos B, Cucinotta D.

Diabetes Res Clin Pract. 2017 Oct;132:108-117. doi: 10.1016/j.diabres.2017.07.026. Epub 2017 Jul 28.

PMID:
28829977
22.

Oxidative Stress: Harms and Benefits for Human Health.

Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, Squadrito F, Altavilla D, Bitto A.

Oxid Med Cell Longev. 2017;2017:8416763. doi: 10.1155/2017/8416763. Epub 2017 Jul 27. Review.

23.

Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury.

Irrera N, Pizzino G, Calò M, Pallio G, Mannino F, Famà F, Arcoraci V, Fodale V, David A, Francesca C, Minutoli L, Mazzon E, Bramanti P, Squadrito F, Altavilla D, Bitto A.

Front Pharmacol. 2017 Jul 14;8:459. doi: 10.3389/fphar.2017.00459. eCollection 2017.

24.

Dietary Management of Skin Health: The Role of Genistein.

Irrera N, Pizzino G, D'Anna R, Vaccaro M, Arcoraci V, Squadrito F, Altavilla D, Bitto A.

Nutrients. 2017 Jun 17;9(6). pii: E622. doi: 10.3390/nu9060622. Review.

25.

Genistein Supplementation and Cardiac Function in Postmenopausal Women with Metabolic Syndrome: Results from a Pilot Strain-Echo Study.

De Gregorio C, Marini H, Alibrandi A, Di Benedetto A, Bitto A, Adamo EB, Altavilla D, Irace C, Di Vieste G, Pancaldo D, Granese R, Atteritano M, Corrao S, Licata G, Squadrito F, Arcoraci V.

Nutrients. 2017 Jun 7;9(6). pii: E584. doi: 10.3390/nu9060584.

26.

Effects of PCB-126 on aryl hydrocarbon receptor, ubiquitin and p53 expression levels in Sparus aurata.

Calò M, Licata P, Bitto A, Lo Cascio P, Giarratana F, Altavilla D.

Exp Toxicol Pathol. 2017 May 25. pii: S0940-2993(16)30221-4. doi: 10.1016/j.etp.2017.04.005. [Epub ahead of print]

PMID:
28552628
27.

Pharmacological Activity and Clinical Use of PDRN.

Squadrito F, Bitto A, Irrera N, Pizzino G, Pallio G, Minutoli L, Altavilla D.

Front Pharmacol. 2017 Apr 26;8:224. doi: 10.3389/fphar.2017.00224. eCollection 2017. Review.

28.

PCB-126 effects on aryl hydrocarbon receptor, ubiquitin and p53 expression levels in a fish product (Sparus aurata L.).

Calò M, Bitto A, Lo Cascio P, Giarratana F, Altavilla D, Gervasi T, Campone L, Cicero N, Licata P.

Nat Prod Res. 2018 May;32(10):1136-1144. doi: 10.1080/14786419.2017.1320794. Epub 2017 Apr 24.

PMID:
28434239
29.

Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.

Bennett CF, Kwon JJ, Chen C, Russell J, Acosta K, Burnaevskiy N, Crane MM, Bitto A, Vander Wende H, Simko M, Pineda V, Rossner R, Wasko BM, Choi H, Chen S, Park S, Jafari G, Sands B, Perez Olsen C, Mendenhall AR, Morgan PG, Kaeberlein M.

PLoS Genet. 2017 Mar 29;13(3):e1006695. doi: 10.1371/journal.pgen.1006695. eCollection 2017 Mar.

30.

Antiosteoporotic Activity of Genistein Aglycone in Postmenopausal Women: Evidence from a Post-Hoc Analysis of a Multicenter Randomized Controlled Trial.

Arcoraci V, Atteritano M, Squadrito F, D'Anna R, Marini H, Santoro D, Minutoli L, Messina S, Altavilla D, Bitto A.

Nutrients. 2017 Feb 22;9(2). pii: E179. doi: 10.3390/nu9020179.

31.

Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice.

Bitto A, Giuliani D, Pallio G, Irrera N, Vandini E, Canalini F, Zaffe D, Ottani A, Minutoli L, Rinaldi M, Guarini S, Squadrito F, Altavilla D.

Inflamm Res. 2017 May;66(5):389-398. doi: 10.1007/s00011-017-1022-x. Epub 2017 Feb 25.

PMID:
28238167
32.

Polydeoxyribonucleotide, an Adenosine-A2A Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury.

Squadrito F, Micali A, Rinaldi M, Irrera N, Marini H, Puzzolo D, Pisani A, Lorenzini C, Valenti A, Laurà R, Germanà A, Bitto A, Pizzino G, Pallio G, Altavilla D, Minutoli L.

Front Pharmacol. 2017 Jan 10;7:537. doi: 10.3389/fphar.2016.00537. eCollection 2016.

33.

Takotsubo syndrome and estrogen receptor genes: partners in crime?

Pizzino G, Bitto A, Crea P, Khandheria B, Vriz O, Carerj S, Squadrito F, Minisini R, Citro R, Cusmà-Piccione M, Madaffari A, Andò G, Altavilla D, Zito C.

J Cardiovasc Med (Hagerstown). 2017 Apr;18(4):268-276. doi: 10.2459/JCM.0000000000000500.

PMID:
28118181
34.

BAY 11-7082 inhibits the NF-κB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis.

Irrera N, Vaccaro M, Bitto A, Pallio G, Pizzino G, Lentini M, Arcoraci V, Minutoli L, Scuruchi M, Cutroneo G, Anastasi GP, Ettari R, Squadrito F, Altavilla D.

Clin Sci (Lond). 2017 Mar 1;131(6):487-498. doi: 10.1042/CS20160645. Epub 2017 Jan 17.

PMID:
28096316
35.

Skin Involvement and Pulmonary Hypertension Are Associated with Vitamin D Insufficiency in Scleroderma.

Atteritano M, Santoro D, Corallo G, Visalli E, Buemi M, Catalano A, Lasco A, Bitto A, Squadrito F.

Int J Mol Sci. 2016 Dec 14;17(12). pii: E2103.

36.

Adenosine Receptor Stimulation by Polydeoxyribonucleotide Improves Tissue Repair and Symptomology in Experimental Colitis.

Pallio G, Bitto A, Pizzino G, Galfo F, Irrera N, Squadrito F, Squadrito G, Pallio S, Anastasi GP, Cutroneo G, Macrì A, Altavilla D.

Front Pharmacol. 2016 Aug 23;7:273. doi: 10.3389/fphar.2016.00273. eCollection 2016.

37.

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice.

Bitto A, Ito TK, Pineda VV, LeTexier NJ, Huang HZ, Sutlief E, Tung H, Vizzini N, Chen B, Smith K, Meza D, Yajima M, Beyer RP, Kerr KF, Davis DJ, Gillespie CH, Snyder JM, Treuting PM, Kaeberlein M.

Elife. 2016 Aug 23;5. pii: e16351. doi: 10.7554/eLife.16351.

38.

Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.

Pallio G, Bitto A, Pizzino G, Galfo F, Irrera N, Minutoli L, Arcoraci V, Squadrito G, Macrì A, Squadrito F, Altavilla D.

Eur J Pharmacol. 2016 Oct 15;789:152-162. doi: 10.1016/j.ejphar.2016.07.033. Epub 2016 Jul 21.

PMID:
27450484
39.

Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening.

Di Giovanni C, Ettari R, Sarno S, Rotondo A, Bitto A, Squadrito F, Altavilla D, Schirmeister T, Novellino E, Grasso S, Zappalà M, Lavecchia A.

Eur J Med Chem. 2016 Oct 4;121:578-591. doi: 10.1016/j.ejmech.2016.05.049. Epub 2016 May 27.

PMID:
27318981
40.

ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury.

Minutoli L, Puzzolo D, Rinaldi M, Irrera N, Marini H, Arcoraci V, Bitto A, Crea G, Pisani A, Squadrito F, Trichilo V, Bruschetta D, Micali A, Altavilla D.

Oxid Med Cell Longev. 2016;2016:2183026. doi: 10.1155/2016/2183026. Epub 2016 Apr 5. Review.

41.

Visfatin correlates with hot flashes in postmenopausal women with metabolic syndrome: effects of genistein.

Bitto A, Arcoraci V, Alibrandi A, D'Anna R, Corrado F, Atteritano M, Minutoli L, Altavilla D, Squadrito F.

Endocrine. 2017 Mar;55(3):899-906. doi: 10.1007/s12020-016-0968-8. Epub 2016 Apr 28.

PMID:
27126198
42.

Immunoproteasome-Selective Inhibitors: A Promising Strategy to Treat Hematologic Malignancies, Autoimmune and Inflammatory Diseases.

Ettari R, Previti S, Bitto A, Grasso S, Zappalà M.

Curr Med Chem. 2016;23(12):1217-38. Review.

PMID:
26965184
43.

Increased Serum HMGB-1, ICAM-1 and Metalloproteinase-9 Levels in Buerger's Patients.

De Caridi G, Bitto A, Massara M, Pallio G, Pizzino G, Serra R, Altavilla D, Squadrito F, Spinelli F.

Curr Vasc Pharmacol. 2016;14(4):382-7.

PMID:
26935815
44.

Genomic Variations Affecting Biological Effects of Statins.

Bitto A, Pallio G, Messina S, Arcoraci V, Pizzino G, Russo GT, Pallio S, Squadrito F, Altavilla D.

Curr Drug Metab. 2016;17(6):566-72. Review.

PMID:
26892732
45.

Simvastatin prevents vascular complications in the chronic reactive oxygen species murine model of systemic sclerosis.

Bitto A, Bagnato GL, Pizzino G, Roberts WN, Irrera N, Minutoli L, Russo G, Squadrito F, Saitta A, Bagnato GF, Altavilla D.

Free Radic Res. 2016;50(5):514-22. doi: 10.3109/10715762.2016.1149171. Epub 2016 Mar 17.

PMID:
26846205
46.

Erratum: Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood-Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice.

Minutoli L, Micali A, Pisani A, Puzzolo D, Bitto A, Rinaldi M, Pizzino G, Irrera N, Galfo F, Arena S, Pallio G, Mecchio A, Germanà A, Bruschetta D, Laurà R, Magno C, Marini H, Squadrito F, Altavilla D.

Toxicol Sci. 2016 Jan;149(1):270. doi: 10.1093/toxsci/kfv247. Epub 2015 Dec 3. No abstract available.

PMID:
26637550
47.

Biochemical Genetic Pathways that Modulate Aging in Multiple Species.

Bitto A, Wang AM, Bennett CF, Kaeberlein M.

Cold Spring Harb Perspect Med. 2015 Nov 2;5(11). pii: a025114. doi: 10.1101/cshperspect.a025114. Review.

48.

Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood–Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice [corrected].

Minutoli L, Micali A, Pisani A, Puzzolo D, Bitto A, Rinaldi M, Pizzino G, Irrera N, Galfo F, Arena S, Pallio G, Mecchio A, Germanà A, Bruschetta D, Laurà R, Magno C, Marini H, Squadrito F, Altavilla D.

Toxicol Sci. 2015 Nov;148(1):311-29. doi: 10.1093/toxsci/kfv185. Epub 2015 Sep 30. Erratum in: Toxicol Sci. 2015 Dec 3;149(1):270.

PMID:
26424772
49.

NLRP3 Inflammasome Involvement in the Organ Damage and Impaired Spermatogenesis Induced by Testicular Ischemia and Reperfusion in Mice.

Minutoli L, Antonuccio P, Irrera N, Rinaldi M, Bitto A, Marini H, Pizzino G, Romeo C, Pisani A, Santoro G, Puzzolo D, Magno C, Squadrito F, Micali A, Altavilla D.

J Pharmacol Exp Ther. 2015 Dec;355(3):370-80. doi: 10.1124/jpet.115.226936. Epub 2015 Sep 25.

PMID:
26407722
50.

Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele.

Minutoli L, Arena S, Antonuccio P, Romeo C, Bitto A, Magno C, Rinaldi M, Micali A, Irrera N, Pizzino G, Galfo F, Squadrito F, Altavilla D, Marini H.

Biomed Res Int. 2015;2015:248976. doi: 10.1155/2015/248976. Epub 2015 Aug 4.

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