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Items: 48

1.

Chronic meningoencephalitis with mixed pathology mimics progressive supranuclear palsy.

Dale ML, Erten-Lyons D, Bittner F, Woltjer R.

BMJ Case Rep. 2018 Nov 28;11(1). pii: e227119. doi: 10.1136/bcr-2018-227119.

PMID:
30567127
2.

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Demyelination Comorbid With Leber Hereditary Optic Neuropathy.

Bittner F, Falardeau J, Spain RI.

JAMA Neurol. 2018 Oct 22. doi: 10.1001/jamaneurol.2018.3207. [Epub ahead of print] No abstract available.

PMID:
30422222
3.

Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes.

Kubitza C, Bittner F, Ginsel C, Havemeyer A, Clement B, Scheidig AJ.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11958-11963. doi: 10.1073/pnas.1808576115. Epub 2018 Nov 5.

4.

An autoimmune disease risk SNP, rs2281808, in SIRPG is associated with reduced expression of SIRPγ and heightened effector state in human CD8 T-cells.

Sinha S, Borcherding N, Renavikar PS, Crawford MP, Tsalikian E, Tansey M, Shivapour ET, Bittner F, Kamholz J, Olalde H, Gibson E, Karandikar NJ.

Sci Rep. 2018 Oct 18;8(1):15440. doi: 10.1038/s41598-018-33901-1.

5.

T4 lysozyme-facilitated crystallization of the human molybdenum cofactor-dependent enzyme mARC.

Kubitza C, Ginsel C, Bittner F, Havemeyer A, Clement B, Scheidig AJ.

Acta Crystallogr F Struct Biol Commun. 2018 Jun 1;74(Pt 6):337-344. doi: 10.1107/S2053230X18006921. Epub 2018 May 17.

PMID:
29870017
6.

Detoxification of Trimethylamine N-Oxide by the Mitochondrial Amidoxime Reducing Component mARC.

Schneider J, Girreser U, Havemeyer A, Bittner F, Clement B.

Chem Res Toxicol. 2018 Jun 18;31(6):447-453. doi: 10.1021/acs.chemrestox.7b00329. Epub 2018 Jun 1.

PMID:
29856598
7.

Scale-Up of the Electrodeposition of ZnO/Eosin Y Hybrid Thin Films for the Fabrication of Flexible Dye-Sensitized Solar Cell Modules.

Bittner F, Oekermann T, Wark M.

Materials (Basel). 2018 Feb 2;11(2). pii: E232. doi: 10.3390/ma11020232.

8.

Lipoic Acid Pharmacokinetics at Baseline and 1 year in Secondary Progressive MS.

Bittner F, Murchison C, Koop D, Bourdette D, Spain R.

Neurol Neuroimmunol Neuroinflamm. 2017 Jun 28;4(5):e380. doi: 10.1212/NXI.0000000000000380. eCollection 2017 Sep. No abstract available.

9.

Cloning and Characterization of Cheilanthifoline and Stylopine Synthase Genes from Chelidonium majus.

Yahyazadeh M, Ratmoyo P, Bittner F, Sato F, Selmar D.

Plant Cell Physiol. 2017 Aug 1;58(8):1421-1430. doi: 10.1093/pcp/pcx077.

PMID:
28633475
10.

Molybdenum and iron mutually impact their homeostasis in cucumber (Cucumis sativus) plants.

Vigani G, Di Silvestre D, Agresta AM, Donnini S, Mauri P, Gehl C, Bittner F, Murgia I.

New Phytol. 2017 Feb;213(3):1222-1241. doi: 10.1111/nph.14214. Epub 2016 Oct 13.

11.

Defining the Role of the NADH-Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System.

Plitzko B, Havemeyer A, Bork B, Bittner F, Mendel R, Clement B.

Drug Metab Dispos. 2016 Oct;44(10):1617-21. doi: 10.1124/dmd.116.071845. Epub 2016 Jul 28.

PMID:
27469001
12.

Dual and Opposing Roles of Xanthine Dehydrogenase in Defense-Associated Reactive Oxygen Species Metabolism in Arabidopsis.

Ma X, Wang W, Bittner F, Schmidt N, Berkey R, Zhang L, King H, Zhang Y, Feng J, Wen Y, Tan L, Li Y, Zhang Q, Deng Z, Xiong X, Xiao S.

Plant Cell. 2016 May;28(5):1108-26. doi: 10.1105/tpc.15.00880. Epub 2016 May 5.

13.

Oxyl and hydroxyl radical transfer in mitochondrial amidoxime reducing component-catalyzed nitrite reduction.

Yang J, Giles LJ, Ruppelt C, Mendel RR, Bittner F, Kirk ML.

J Am Chem Soc. 2015 Apr 29;137(16):5276-9. doi: 10.1021/jacs.5b01112. Epub 2015 Apr 21.

14.

Sulphur shuttling across a chaperone during molybdenum cofactor maturation.

Arnoux P, Ruppelt C, Oudouhou F, Lavergne J, Siponen MI, Toci R, Mendel RR, Bittner F, Pignol D, Magalon A, Walburger A.

Nat Commun. 2015 Feb 4;6:6148. doi: 10.1038/ncomms7148.

PMID:
25649206
15.

Electrochemical and mARC-catalyzed enzymatic reduction of para-substituted benzamidoximes: consequences for the prodrug concept "amidoximes instead of amidines".

Bauch E, Reichmann D, Mendel RR, Bittner F, Manke AM, Kurz P, Girreser U, Havemeyer A, Clement B.

ChemMedChem. 2015 Feb;10(2):360-7. doi: 10.1002/cmdc.201402437. Epub 2014 Dec 15.

PMID:
25512261
16.

Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC).

Ott G, Plitzko B, Krischkowski C, Reichmann D, Bittner F, Mendel RR, Kunze T, Clement B, Havemeyer A.

Chem Res Toxicol. 2014 Oct 20;27(10):1687-95. doi: 10.1021/tx500174u. Epub 2014 Sep 18.

PMID:
25170804
17.

Molybdenum site structure of MOSC family proteins.

Giles LJ, Ruppelt C, Yang J, Mendel RR, Bittner F, Kirk ML.

Inorg Chem. 2014 Sep 15;53(18):9460-2. doi: 10.1021/ic5015863. Epub 2014 Aug 28.

18.

The mitochondrial amidoxime reducing component (mARC): involvement in metabolic reduction of N-oxides, oximes and N-hydroxyamidinohydrazones.

Jakobs HH, Froriep D, Havemeyer A, Mendel RR, Bittner F, Clement B.

ChemMedChem. 2014 Oct;9(10):2381-7. doi: 10.1002/cmdc.201402127. Epub 2014 Jul 8.

PMID:
25045021
19.

Molybdenum metabolism in plants and crosstalk to iron.

Bittner F.

Front Plant Sci. 2014 Feb 7;5:28. doi: 10.3389/fpls.2014.00028. eCollection 2014. Review.

20.

Sensitivity and specificity of presumptive tests for blood, saliva and semen.

Vennemann M, Scott G, Curran L, Bittner F, Tobe SS.

Forensic Sci Med Pathol. 2014 Mar;10(1):69-75. doi: 10.1007/s12024-013-9515-6. Epub 2014 Jan 18.

PMID:
24443142
21.

Functional characterization of protein variants encoded by nonsynonymous single nucleotide polymorphisms in MARC1 and MARC2 in healthy Caucasians.

Ott G, Reichmann D, Boerger C, Cascorbi I, Bittner F, Mendel RR, Kunze T, Clement B, Havemeyer A.

Drug Metab Dispos. 2014 Apr;42(4):718-25. doi: 10.1124/dmd.113.055202. Epub 2014 Jan 14.

PMID:
24423752
22.

The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells.

Plitzko B, Ott G, Reichmann D, Henderson CJ, Wolf CR, Mendel R, Bittner F, Clement B, Havemeyer A.

J Biol Chem. 2013 Jul 12;288(28):20228-37. doi: 10.1074/jbc.M113.474916. Epub 2013 May 23.

23.

Activation of the anti-cancer agent upamostat by the mARC enzyme system.

Froriep D, Clement B, Bittner F, Mendel RR, Reichmann D, Schmalix W, Havemeyer A.

Xenobiotica. 2013 Sep;43(9):780-4. doi: 10.3109/00498254.2013.767481. Epub 2013 Feb 4.

PMID:
23379481
24.

The stomatal response to reduced relative humidity requires guard cell-autonomous ABA synthesis.

Bauer H, Ache P, Lautner S, Fromm J, Hartung W, Al-Rasheid KA, Sonnewald S, Sonnewald U, Kneitz S, Lachmann N, Mendel RR, Bittner F, Hetherington AM, Hedrich R.

Curr Biol. 2013 Jan 7;23(1):53-7. doi: 10.1016/j.cub.2012.11.022. Epub 2012 Dec 6.

25.

Identification of superoxide production by Arabidopsis thaliana aldehyde oxidases AAO1 and AAO3.

Zarepour M, Simon K, Wilch M, Nieländer U, Koshiba T, Seo M, Lindel T, Bittner F.

Plant Mol Biol. 2012 Dec;80(6):659-71. doi: 10.1007/s11103-012-9975-1. Epub 2012 Oct 14.

PMID:
23065119
26.

The mitochondrial Amidoxime Reducing Component (mARC) is involved in detoxification of N-hydroxylated base analogues.

Krompholz N, Krischkowski C, Reichmann D, Garbe-Schönberg D, Mendel RR, Bittner F, Clement B, Havemeyer A.

Chem Res Toxicol. 2012 Nov 19;25(11):2443-50. doi: 10.1021/tx300298m. Epub 2012 Aug 27.

PMID:
22924387
27.

A sulfurtransferase is essential for activity of formate dehydrogenases in Escherichia coli.

Thomé R, Gust A, Toci R, Mendel R, Bittner F, Magalon A, Walburger A.

J Biol Chem. 2012 Feb 10;287(7):4671-8. doi: 10.1074/jbc.M111.327122. Epub 2011 Dec 22.

28.

Identification of persulfide-binding and disulfide-forming cysteine residues in the NifS-like domain of the molybdenum cofactor sulfurase ABA3 by cysteine-scanning mutagenesis.

Lehrke M, Rump S, Heidenreich T, Wissing J, Mendel RR, Bittner F.

Biochem J. 2012 Feb 1;441(3):823-32. doi: 10.1042/BJ20111170.

PMID:
22004669
29.

Structural studies of the molybdenum center of mitochondrial amidoxime reducing component (mARC) by pulsed EPR spectroscopy and 17O-labeling.

Rajapakshe A, Astashkin AV, Klein EL, Reichmann D, Mendel RR, Bittner F, Enemark JH.

Biochemistry. 2011 Oct 18;50(41):8813-22. doi: 10.1021/bi2005762. Epub 2011 Sep 22.

30.

Identification of an Arabidopsis solute carrier critical for intracellular transport and inter-organ allocation of molybdate.

Gasber A, Klaumann S, Trentmann O, Trampczynska A, Clemens S, Schneider S, Sauer N, Feifer I, Bittner F, Mendel RR, Neuhaus HE.

Plant Biol (Stuttg). 2011 Sep;13(5):710-8. doi: 10.1111/j.1438-8677.2011.00448.x. Epub 2011 Feb 11.

PMID:
21815974
31.

Molybdenum enzymes in higher organisms.

Hille R, Nishino T, Bittner F.

Coord Chem Rev. 2011 May 1;255(9-10):1179-1205.

32.

Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC).

Kotthaus J, Wahl B, Havemeyer A, Kotthaus J, Schade D, Garbe-Schönberg D, Mendel R, Bittner F, Clement B.

Biochem J. 2011 Jan 15;433(2):383-91. doi: 10.1042/BJ20100960.

PMID:
21029045
33.

Biochemical and spectroscopic characterization of the human mitochondrial amidoxime reducing components hmARC-1 and hmARC-2 suggests the existence of a new molybdenum enzyme family in eukaryotes.

Wahl B, Reichmann D, Niks D, Krompholz N, Havemeyer A, Clement B, Messerschmidt T, Rothkegel M, Biester H, Hille R, Mendel RR, Bittner F.

J Biol Chem. 2010 Nov 26;285(48):37847-59. doi: 10.1074/jbc.M110.169532. Epub 2010 Sep 22.

34.

Reduction of N-hydroxy-sulfonamides, including N-hydroxy-valdecoxib, by the molybdenum-containing enzyme mARC.

Havemeyer A, Grünewald S, Wahl B, Bittner F, Mendel R, Erdélyi P, Fischer J, Clement B.

Drug Metab Dispos. 2010 Nov;38(11):1917-21. doi: 10.1124/dmd.110.032813. Epub 2010 Aug 10.

PMID:
20699408
35.

A novel role for Arabidopsis mitochondrial ABC transporter ATM3 in molybdenum cofactor biosynthesis.

Teschner J, Lachmann N, Schulze J, Geisler M, Selbach K, Santamaria-Araujo J, Balk J, Mendel RR, Bittner F.

Plant Cell. 2010 Feb;22(2):468-80. doi: 10.1105/tpc.109.068478. Epub 2010 Feb 17.

36.

Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity.

Zarepour M, Kaspari K, Stagge S, Rethmeier R, Mendel RR, Bittner F.

Plant Mol Biol. 2010 Feb;72(3):301-10. doi: 10.1007/s11103-009-9570-2. Epub 2009 Nov 14.

PMID:
19915948
37.

On the regulation of photosynthesis by excitonic interactions between carotenoids and chlorophylls.

Bode S, Quentmeier CC, Liao PN, Hafi N, Barros T, Wilk L, Bittner F, Walla PJ.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12311-6. doi: 10.1073/pnas.0903536106. Epub 2009 Jul 15.

38.

Identification of a novel E3 ubiquitin ligase that is required for suppression of premature senescence in Arabidopsis.

Raab S, Drechsel G, Zarepour M, Hartung W, Koshiba T, Bittner F, Hoth S.

Plant J. 2009 Jul;59(1):39-51. doi: 10.1111/j.1365-313X.2009.03846.x. Epub 2009 Feb 26. Erratum in: Plant J. 2009 Dec;60(5):929.

39.

The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs.

Gruenewald S, Wahl B, Bittner F, Hungeling H, Kanzow S, Kotthaus J, Schwering U, Mendel RR, Clement B.

J Med Chem. 2008 Dec 25;51(24):8173-7. doi: 10.1021/jm8010417.

PMID:
19053771
40.

Binding of sulfurated molybdenum cofactor to the C-terminal domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.

Wollers S, Heidenreich T, Zarepour M, Zachmann D, Kraft C, Zhao Y, Mendel RR, Bittner F.

J Biol Chem. 2008 Apr 11;283(15):9642-50. doi: 10.1074/jbc.M708549200. Epub 2008 Feb 7.

41.

Transient expression of AtNCED3 and AAO3 genes in guard cells causes stomatal closure in Vicia faba.

Melhorn V, Matsumi K, Koiwai H, Ikegami K, Okamoto M, Nambara E, Bittner F, Koshiba T.

J Plant Res. 2008 Jan;121(1):125-31. Epub 2007 Dec 4.

PMID:
18060348
42.

Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme.

Havemeyer A, Bittner F, Wollers S, Mendel R, Kunze T, Clement B.

J Biol Chem. 2006 Nov 17;281(46):34796-802. Epub 2006 Sep 13.

43.

Cell biology of molybdenum.

Mendel RR, Bittner F.

Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12. Review.

44.

Transgenic barley plants overexpressing a 13-lipoxygenase to modify oxylipin signature.

Sharma VK, Monostori T, Göbel C, Hänsch R, Bittner F, Wasternack C, Feussner I, Mendel RR, Hause B, Schulze J.

Phytochemistry. 2006 Feb;67(3):264-76. Epub 2005 Dec 27.

PMID:
16376956
45.

Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.

Heidenreich T, Wollers S, Mendel RR, Bittner F.

J Biol Chem. 2005 Feb 11;280(6):4213-8. Epub 2004 Nov 22.

46.

Tandem orientation of duplicated xanthine dehydrogenase genes from Arabidopsis thaliana: differential gene expression and enzyme activities.

Hesberg C, Hänsch R, Mendel RR, Bittner F.

J Biol Chem. 2004 Apr 2;279(14):13547-54. Epub 2004 Jan 15.

47.
48.

The molybdenum cofactor biosynthetic protein Cnx1 complements molybdate-repairable mutants, transfers molybdenum to the metal binding pterin, and is associated with the cytoskeleton.

Schwarz G, Schulze J, Bittner F, Eilers T, Kuper J, Bollmann G, Nerlich A, Brinkmann H, Mendel RR.

Plant Cell. 2000 Dec;12(12):2455-2472.

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