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Pretest probability for patients with suspected obstructive coronary artery disease: re-evaluating Diamond-Forrester for the contemporary era and clinical implications: insights from the PROMISE trial.

Foldyna B, Udelson JE, Karády J, Banerji D, Lu MT, Mayrhofer T, Bittner DO, Meyersohn NM, Emami H, Genders TSS, Fordyce CB, Ferencik M, Douglas PS, Hoffmann U.

Eur Heart J Cardiovasc Imaging. 2018 Dec 5. doi: 10.1093/ehjci/jey182. [Epub ahead of print]


Subclinical Burden of Coronary Artery Calcium in Patients With Coarctation of the Aorta.

Krishnamurthy Y, Stefanescu Schmidt AC, Bittner DO, Scholtz JE, Bui A, Reddy R, Youniss MA, Donohoe K, Flannery LD, Fahed AC, Ghoshhajra BB, DeFaria Yeh D, Bhatt AB.

Am J Cardiol. 2018 Oct 21. pii: S0002-9149(18)31975-1. doi: 10.1016/j.amjcard.2018.10.017. [Epub ahead of print]


Rapid buildup of sympatric species diversity in Alpine whitefish.

Doenz CJ, Bittner D, Vonlanthen P, Wagner CE, Seehausen O.

Ecol Evol. 2018 Aug 29;8(18):9398-9412. doi: 10.1002/ece3.4375. eCollection 2018 Sep.


Coronary Computed Tomography Angiography-Specific Definitions of High-Risk Plaque Features Improve Detection of Acute Coronary Syndrome.

Bittner DO, Mayrhofer T, Puchner SB, Lu MT, Maurovich-Horvat P, Ghemigian K, Kitslaar PH, Broersen A, Bamberg F, Truong QA, Schlett CL, Hoffmann U, Ferencik M.

Circ Cardiovasc Imaging. 2018 Aug;11(8):e007657. doi: 10.1161/CIRCIMAGING.118.007657.


Biomarkers of Neurodegeneration in Autoimmune-Mediated Encephalitis.

Körtvelyessy P, Prüss H, Thurner L, Maetzler W, Vittore-Welliong D, Schultze-Amberger J, Heinze HJ, Reinhold D, Leypoldt F, Schreiber S, Bittner D.

Front Neurol. 2018 Sep 19;9:668. doi: 10.3389/fneur.2018.00668. eCollection 2018.


Significance of CSF NfL and tau in ALS.

Schreiber S, Spotorno N, Schreiber F, Acosta-Cabronero J, Kaufmann J, Machts J, Debska-Vielhaber G, Garz C, Bittner D, Hensiek N, Dengler R, Petri S, Nestor PJ, Vielhaber S.

J Neurol. 2018 Nov;265(11):2633-2645. doi: 10.1007/s00415-018-9043-0. Epub 2018 Sep 5.


CSF Biomarkers of Neurodegeneration in Progressive Non-fluent Aphasia and Other Forms of Frontotemporal Dementia: Clues for Pathomechanisms?

Körtvelyessy P, Heinze HJ, Prudlo J, Bittner D.

Front Neurol. 2018 Jul 2;9:504. doi: 10.3389/fneur.2018.00504. eCollection 2018.


VZV-associated acute retinal necrosis in a patient with MS treated with natalizumab.

Pawlitzki M, Teuber J, Campe C, Wagner M, Schuart C, Paul F, Bittner D.

Neurol Neuroimmunol Neuroinflamm. 2018 Jul 9;5(5):e475. doi: 10.1212/NXI.0000000000000475. eCollection 2018 Sep. No abstract available.


Diagnostic Performance of Coronary CTA in Intermediate-to-High-Risk Patients for Suspected Acute Coronary Syndrome: Results From an Emergency Department Registry.

Scholtz JE, Addison D, Bittner DO, Janjua S, Foldyna B, Hedgire S, Staziaki PV, Januzzi JL Jr, Nagurney JT, Meyersohn N, Lu MT, Neilan TG, Hoffmann U, Ghoshhajra BB.

JACC Cardiovasc Imaging. 2018 Sep;11(9):1369-1371. doi: 10.1016/j.jcmg.2018.03.014. Epub 2018 May 16. No abstract available.


Differences in the association of total versus local coronary artery calcium with acute coronary syndrome and culprit lesions in patients with acute chest pain: The coronary calcium paradox.

Puchner SB, Mayrhofer T, Park J, Lu MT, Liu T, Maurovich-Horvat P, Ghemigian K, Bittner DO, Fleg JL, Udelson JE, Truong QA, Hoffmann U, Ferencik M.

Atherosclerosis. 2018 Jul;274:251-257. doi: 10.1016/j.atherosclerosis.2018.04.017. Epub 2018 Apr 17.


The adversative connectives aber and but in conversational corpora.

Gülzow I, Bartlitz V, Kuehnast M, Golcher F, Bittner D.

J Child Lang. 2018 Sep;45(5):1212-1226. doi: 10.1017/S0305000917000630. Epub 2018 Mar 9.


CT-derived left ventricular global strain in aortic valve stenosis patients: A comparative analysis pre and post transcatheter aortic valve implantation.

Marwan M, Ammon F, Bittner D, Röther J, Mekkhala N, Hell M, Schuhbaeck A, Gitsioudis G, Feyrer R, Schlundt C, Achenbach S, Arnold M.

J Cardiovasc Comput Tomogr. 2018 May - Jun;12(3):240-244. doi: 10.1016/j.jcct.2018.01.010. Epub 2018 Feb 3.


Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease.

Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M.

Brain. 2018 Apr 1;141(4):1186-1200. doi: 10.1093/brain/awy008.


Perivascular Epicardial Fat Stranding at Coronary CT Angiography: A Marker of Acute Plaque Rupture and Spontaneous Coronary Artery Dissection.

Hedgire S, Baliyan V, Zucker EJ, Bittner DO, Staziaki PV, Takx RAP, Scholtz JE, Meyersohn N, Hoffmann U, Ghoshhajra B.

Radiology. 2018 Jun;287(3):808-815. doi: 10.1148/radiol.2017171568. Epub 2018 Feb 5.


Use of High-Risk Coronary Atherosclerotic Plaque Detection for Risk Stratification of Patients With Stable Chest Pain: A Secondary Analysis of the PROMISE Randomized Clinical Trial.

Ferencik M, Mayrhofer T, Bittner DO, Emami H, Puchner SB, Lu MT, Meyersohn NM, Ivanov AV, Adami EC, Patel MR, Mark DB, Udelson JE, Lee KL, Douglas PS, Hoffmann U.

JAMA Cardiol. 2018 Feb 1;3(2):144-152. doi: 10.1001/jamacardio.2017.4973.


Molecular geometries and other properties of H2O⋯AgI and H3N⋯AgI as characterised by rotational spectroscopy and ab initio calculations.

Medcraft C, Gougoula E, Bittner DM, Mullaney JC, Blanco S, Tew DP, Walker NR, Legon AC.

J Chem Phys. 2017 Dec 21;147(23):234308. doi: 10.1063/1.5008744.


Leaflet thrombosis following transcatheter aortic valve implantation.

Marwan M, Mekkhala N, Göller M, Röther J, Bittner D, Schuhbaeck A, Hell M, Muschiol G, Kolwelter J, Feyrer R, Schlundt C, Achenbach S, Arnold M.

J Cardiovasc Comput Tomogr. 2018 Jan - Feb;12(1):8-13. doi: 10.1016/j.jcct.2017.11.002. Epub 2017 Nov 9.


Central Core Laboratory versus Site Interpretation of Coronary CT Angiography: Agreement and Association with Cardiovascular Events in the PROMISE Trial.

Lu MT, Meyersohn NM, Mayrhofer T, Bittner DO, Emami H, Puchner SB, Foldyna B, Mueller ME, Hearne S, Yang C, Achenbach S, Truong QA, Ghoshhajra BB, Patel MR, Ferencik M, Douglas PS, Hoffmann U.

Radiology. 2018 Apr;287(1):87-95. doi: 10.1148/radiol.2017172181. Epub 2017 Nov 27.


Identification of coronary artery calcification can optimize risk stratification in patients with acute chest pain.

Bittner DO, Takx RAP, Staziaki PV, Janjua S, Neilan TG, Meyersohn NM, Lu MT, Prabhakar AM, Nagurney JT, Hoffmann U, Ghoshhajra BB.

Int J Cardiol. 2017 Dec 15;249:473-478. doi: 10.1016/j.ijcard.2017.06.119.


CT Attenuation of Pericoronary Adipose Tissue in Normal Versus Atherosclerotic Coronary Segments as Defined by Intravascular Ultrasound.

Marwan M, Hell M, Schuhbäck A, Gauss S, Bittner D, Pflederer T, Achenbach S.

J Comput Assist Tomogr. 2017 Sep/Oct;41(5):762-767. doi: 10.1097/RCT.0000000000000589.


Age- and sex-based resource utilisation and costs in patients with acute chest pain undergoing cardiac CT angiography: pooled evidence from ROMICAT II and ACRIN-PA trials.

Bamberg F, Mayrhofer T, Ferencik M, Bittner DO, Hallett TR, Janjua S, Schlett CL, Nagurney JT, Udelson JE, Truong QA, Woodard PK, Hollander JE, Litt H, Hoffmann U.

Eur Radiol. 2018 Feb;28(2):851-860. doi: 10.1007/s00330-017-4981-y. Epub 2017 Sep 5.


Prognostic Value of Coronary Artery Calcium in the PROMISE Study (Prospective Multicenter Imaging Study for Evaluation of Chest Pain).

Budoff MJ, Mayrhofer T, Ferencik M, Bittner D, Lee KL, Lu MT, Coles A, Jang J, Krishnam M, Douglas PS, Hoffmann U; PROMISE Investigators.

Circulation. 2017 Nov 21;136(21):1993-2005. doi: 10.1161/CIRCULATIONAHA.117.030578. Epub 2017 Aug 28.


Impact of Coronary Calcification on Clinical Management in Patients With Acute Chest Pain.

Bittner DO, Mayrhofer T, Bamberg F, Hallett TR, Janjua S, Addison D, Nagurney JT, Udelson JE, Lu MT, Truong QA, Woodard PK, Hollander JE, Miller C, Chang AM, Singh H, Litt H, Hoffmann U, Ferencik M.

Circ Cardiovasc Imaging. 2017 May;10(5). pii: e005893. doi: 10.1161/CIRCIMAGING.116.005893.


Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection.

Körtvelyessy P, Huchtemann T, Heinze HJ, Bittner DM.

Int J Mol Sci. 2017 Feb 24;18(3). pii: E490. doi: 10.3390/ijms18030490. Review.


Influence of Cardiovascular Risk Factors on the Prevalence of Coronary Atherosclerosis in Patients with Angiographically Normal Coronary Arteries.

Bittner DO, Klinghammer L, Marwan M, Schmid J, Layritz C, Hoffmann U, Achenbach S, Pflederer T.

Acad Radiol. 2017 May;24(5):580-586. doi: 10.1016/j.acra.2016.12.005. Epub 2017 Feb 3.


Clinical implementation of an emergency department coronary computed tomographic angiography protocol for triage of patients with suspected acute coronary syndrome.

Ghoshhajra BB, Takx RAP, Staziaki PV, Vadvala H, Kim P, Neilan TG, Meyersohn NM, Bittner D, Janjua SA, Mayrhofer T, Greenwald JL, Truong QA, Abbara S, Brown DFM, Januzzi JL, Francis S, Nagurney JT, Hoffmann U; MGH Emergency Cardiac CTA Program Contributors.

Eur Radiol. 2017 Jul;27(7):2784-2793. doi: 10.1007/s00330-016-4562-5. Epub 2016 Nov 24.


Geometries of H2S⋯MI (M = Cu, Ag, Au) complexes studied by rotational spectroscopy: The effect of the metal atom.

Medcraft C, Bittner DM, Tew DP, Walker NR, Legon AC.

J Chem Phys. 2016 Nov 21;145(19):194306.


Combination of Structural MRI and FDG-PET of the Brain Improves Diagnostic Accuracy in Newly Manifested Cognitive Impairment in Geriatric Inpatients.

Ritter K, Lange C, Weygandt M, Mäurer A, Roberts A, Estrella M, Suppa P, Spies L, Prasad V, Steffen I, Apostolova I, Bittner D, Gövercin M, Brenner W, Mende C, Peters O, Seybold J, Fiebach JB, Steinhagen-Thiessen E, Hampel H, Haynes JD, Buchert R.

J Alzheimers Dis. 2016 Oct 18;54(4):1319-1331.


Highly Unsaturated Platinum and Palladium Carbenes PtC3 and PdC3 Isolated and Characterized in the Gas Phase.

Bittner DM, Zaleski DP, Tew DP, Walker NR, Legon AC.

Angew Chem Weinheim Bergstr Ger. 2016 Mar 7;128(11):3832-3835. Epub 2016 Feb 15.


Gas phase complexes of H3NCuF and H3NCuI studied by rotational spectroscopy and ab initio calculations: the effect of X (X = F, Cl, Br, I) in OCCuX and H3NCuX.

Bittner DM, Stephens SL, Zaleski DP, Tew DP, Walker NR, Legon AC.

Phys Chem Chem Phys. 2016 May 21;18(19):13638-45. doi: 10.1039/c6cp01368f. Epub 2016 May 3.


Coronary CT Angiography as a Diagnostic and Prognostic Tool: Perspective from a Multicenter Randomized Controlled Trial: PROMISE.

Bittner DO, Ferencik M, Douglas PS, Hoffmann U.

Curr Cardiol Rep. 2016 May;18(5):40. doi: 10.1007/s11886-016-0718-9.


Contrast volume reduction using third generation dual source computed tomography for the evaluation of patients prior to transcatheter aortic valve implantation.

Bittner DO, Arnold M, Klinghammer L, Schuhbaeck A, Hell MM, Muschiol G, Gauss S, Lell M, Uder M, Hoffmann U, Achenbach S, Marwan M.

Eur Radiol. 2016 Dec;26(12):4497-4504. Epub 2016 Mar 19.


Highly Unsaturated Platinum and Palladium Carbenes PtC3 and PdC3 Isolated and Characterized in the Gas Phase.

Bittner DM, Zaleski DP, Tew DP, Walker NR, Legon AC.

Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3768-71. doi: 10.1002/anie.201511646. Epub 2016 Feb 16.


Characterizing Aging, Mild Cognitive Impairment, and Dementia with Blood-Based Biomarkers and Neuropsychology.

Kleinschmidt M, Schoenfeld R, Göttlich C, Bittner D, Metzner JE, Leplow B, Demuth HU.

J Alzheimers Dis. 2016;50(1):111-26. doi: 10.3233/JAD-143189.


No Change in Executive Performance in ALS Patients: A Longitudinal Neuropsychological Study.

Kasper E, Zydatiss K, Schuster C, Machts J, Bittner D, Kaufmann J, Benecke R, Vielhaber S, Teipel S, Prudlo J.

Neurodegener Dis. 2016;16(3-4):184-91. doi: 10.1159/000440957. Epub 2015 Nov 28.


Interaction of a pseudo-π C-C bond with cuprous and argentous chlorides: Cyclopropane⋯CuCl and cyclopropane⋯AgCl investigated by rotational spectroscopy and ab initio calculations.

Zaleski DP, Mullaney JC, Bittner DM, Tew DP, Walker NR, Legon AC.

J Chem Phys. 2015 Oct 28;143(16):164314. doi: 10.1063/1.4934539.


Hereditary diffuse leukoencephalopathy with spheroids (HDLS) with a novel CSF1R mutation and spinal cord involvement.

Körtvelyessy P, Krägeloh-Mann I, Mawrin C, Heinze HJ, Bittner D, Wieland I, Zenker M, Nestor P.

J Neurol Sci. 2015 Nov 15;358(1-2):515-7. doi: 10.1016/j.jns.2015.09.370. Epub 2015 Sep 28. No abstract available.


Progranulin levels in status epilepticus as a marker of neuronal recovery and neuroprotection.

Huchtemann T, Körtvélyessy P, Feistner H, Heinze HJ, Bittner D.

Epilepsy Behav. 2015 Aug;49:170-2. doi: 10.1016/j.yebeh.2015.06.022. Epub 2015 Jul 23.


The σ-hole interaction between sulfur hexafluoride and ammonia characterised by broadband rotational spectroscopy.

Bittner DM, Zaleski DP, Stephens SL, Walker NR, Legon AC.

Chemphyschem. 2015 Aug 24;16(12):2630-4. doi: 10.1002/cphc.201500455. Epub 2015 Jul 14.


Distortions of ethyne when complexed with a cuprous or argentous halide: the rotational spectrum of C2H2CuF.

Zaleski DP, Stephens SL, Tew DP, Bittner DM, Walker NR, Legon AC.

Phys Chem Chem Phys. 2015 Jul 15;17(29):19230-7. doi: 10.1039/c5cp02248g.


Time and Causation in Discourse: Temporal Proximity, Implicit Causality, and Re-mention Biases.

Dery JE, Bittner D.

J Psycholinguist Res. 2016 Aug;45(4):883-99. doi: 10.1007/s10936-015-9382-2.


Dysexecutive functioning in ALS patients and its clinical implications.

Kasper E, Schuster C, Machts J, Bittner D, Vielhaber S, Benecke R, Teipel S, Prudlo J.

Amyotroph Lateral Scler Frontotemporal Degener. 2015 Jun;16(3-4):160-71. doi: 10.3109/21678421.2015.1026267. Epub 2015 May 12.


A monomeric complex of ammonia and cuprous chloride: H3N⋯CuCl isolated and characterised by rotational spectroscopy and ab initio calculations.

Bittner DM, Zaleski DP, Stephens SL, Tew DP, Walker NR, Legon AC.

J Chem Phys. 2015 Apr 14;142(14):144302. doi: 10.1063/1.4916391.


Progranulin and Amyloid-β Levels: Relationship to Neuropsychology in Frontotemporal and Alzheimer's Disease.

Körtvélyessy P, Gukasjan A, Sweeney-Reed CM, Heinze HJ, Thurner L, Bittner DM.

J Alzheimers Dis. 2015;46(2):375-80. doi: 10.3233/JAD-150069.


Microstructural white matter changes underlying cognitive and behavioural impairment in ALS--an in vivo study using DTI.

Kasper E, Schuster C, Machts J, Kaufmann J, Bittner D, Vielhaber S, Benecke R, Teipel S, Prudlo J.

PLoS One. 2014 Dec 11;9(12):e114543. doi: 10.1371/journal.pone.0114543. eCollection 2014.


High prevalence of NMDA receptor IgA/IgM antibodies in different dementia types.

Doss S, Wandinger KP, Hyman BT, Panzer JA, Synofzik M, Dickerson B, Mollenhauer B, Scherzer CR, Ivinson AJ, Finke C, Schöls L, Müller Vom Hagen J, Trenkwalder C, Jahn H, Höltje M, Biswal BB, Harms L, Ruprecht K, Buchert R, Höglinger GU, Oertel WH, Unger MM, Körtvélyessy P, Bittner D, Priller J, Spruth EJ, Paul F, Meisel A, Lynch DR, Dirnagl U, Endres M, Teegen B, Probst C, Komorowski L, Stöcker W, Dalmau J, Prüss H.

Ann Clin Transl Neurol. 2014 Oct;1(10):822-32. doi: 10.1002/acn3.120. Epub 2014 Oct 18.


Prospectively ECG-triggered high-pitch coronary angiography with third-generation dual-source CT at 70 kVp tube voltage: feasibility, image quality, radiation dose, and effect of iterative reconstruction.

Hell MM, Bittner D, Schuhbaeck A, Muschiol G, Brand M, Lell M, Uder M, Achenbach S, Marwan M.

J Cardiovasc Comput Tomogr. 2014 Nov-Dec;8(6):418-25. doi: 10.1016/j.jcct.2014.09.003. Epub 2014 Sep 16.


Changes in the geometries of C₂H₂ and C₂H₄ on coordination to CuCl revealed by broadband rotational spectroscopy and ab-initio calculations.

Stephens SL, Bittner DM, Mikhailov VA, Mizukami W, Tew DP, Walker NR, Legon AC.

Inorg Chem. 2014 Oct 6;53(19):10722-30. doi: 10.1021/ic501899c. Epub 2014 Sep 18.


Repetitive pupil light reflex: potential marker in Alzheimer's disease?

Bittner DM, Wieseler I, Wilhelm H, Riepe MW, Müller NG.

J Alzheimers Dis. 2014;42(4):1469-77. doi: 10.3233/JAD-140969.


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