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Challenges to achieving and maintaining viral suppression among Canadian children living with perinatal HIV infection in the Early Pediatric Initiation Canada Child Cure Cohort.

Kakkar F, Lee T, Hawkes MT, Brophy J, Lindy S, Singer J, Dieumegard H, Sauve L, Alimenti A, Vaudry W, Seigel S, Tan B, Karatzios C, Lamarre V, Read S, Soudeyns H, Bitnun A; EPIC4 Study Group.

AIDS. 2019 Dec 2. doi: 10.1097/QAD.0000000000002454. [Epub ahead of print]


Congenital anomalies following antenatal exposure to dolutegravir: a Canadian surveillance study.

Money D, Lee T, O'Brien C, Brophy J, Bitnun A, Kakkar F, Boucoiran I, Alimenti A, Vaudry W, Singer J, Sauve LJ; Canadian Perinatal HIV Surveillance Program.

BJOG. 2019 Oct;126(11):1338-1345. doi: 10.1111/1471-0528.15838. Epub 2019 Jul 3.


PANDAS/PANS in childhood: Controversies and evidence.

Wilbur C, Bitnun A, Kronenberg S, Laxer RM, Levy DM, Logan WJ, Shouldice M, Yeh EA.

Paediatr Child Health. 2019 May;24(2):85-91. doi: 10.1093/pch/pxy145. Epub 2018 Dec 9.


Treatment of rituximab-associated chronic CNS enterovirus using IVIg and fluoxetine.

Sham L, Bitnun A, Branson H, Hazrati LN, Dell SD, Yeung RSM, Johnstone J, Yeh EA.

Neurology. 2019 May 7;92(19):916-918. doi: 10.1212/WNL.0000000000007468. Epub 2019 Apr 3. No abstract available.


Clinical correlates of HIV-1 DNA and inducible HIV-1 RNA reservoirs in peripheral blood in children with perinatally acquired HIV-1 infection with sustained virologic suppression for at least 5 years.

Bitnun A, Ransy DG, Brophy J, Kakkar F, Hawkes M, Samson L, Annabi B, Pagliuzza A, Morand JA, Sauve L, Chomont N, Lavoie S, Kim J, Sandstrom P, Wender P, Lee T, Singer J, Read SE, Soudeyns H; EPIC Research Group.

Clin Infect Dis. 2019 Mar 28. pii: ciz251. doi: 10.1093/cid/ciz251. [Epub ahead of print]


Brief Report: Higher Levels of Angiopoietin-1 Are Associated With Early and Sustained Viral Suppression in Children Living With Vertically Acquired HIV.

Gulhati V, Soo J, Ransy DG, Brophy J, Kakkar F, Bitnun A, Samson L, Read S, Soudeyns H, Hawkes MT; for EPIC4 Study Group.

J Acquir Immune Defic Syndr. 2019 Apr 15;80(5):590-595. doi: 10.1097/QAI.0000000000001955.


Sporadic Creutzfeldt-Jakob Disease in a Young Girl With Unusually Long Survival.

D'Arcy CE, Bitnun A, Coulthart MB, D'Amour R, Friedman J, Knox JD, Rapoport A, Carter S, Widjaja E, Hazrati LN, Jansen GH.

J Neuropathol Exp Neurol. 2019 Apr 1;78(4):373-378. doi: 10.1093/jnen/nlz013.


Breastfeeding by Women Living With Human Immunodeficiency Virus in a Resource-Rich Setting: A Case Series of Maternal and Infant Management and Outcomes.

Nashid N, Khan S, Loutfy M, MacGillivray J, Yudin MH, Campbell DM, Barozzino T, Baqi M, Read SE, Bitnun A.

J Pediatric Infect Dis Soc. 2019 Feb 8. doi: 10.1093/jpids/piz003. [Epub ahead of print]


Acute flaccid myelitis.

Gill PJ, Bitnun A, Yeh EA.

CMAJ. 2018 Dec 3;190(48):E1418. doi: 10.1503/cmaj.181442. No abstract available.


Adenovirus-Associated Central Nervous System Disease in Children.

Schwartz KL, Richardson SE, MacGregor D, Mahant S, Raghuram K, Bitnun A.

J Pediatr. 2019 Feb;205:130-137. doi: 10.1016/j.jpeds.2018.09.036. Epub 2018 Nov 6.


Acute Flaccid Myelitis in a 10-Year-Old Girl.

Ertl-Wagner B, Branson H, Shroff M, Bitnun A, Yeh EA.

Radiology. 2019 Jan;290(1):31. doi: 10.1148/radiol.2018182430. Epub 2018 Nov 6. No abstract available.


Acute Flaccid Paralysis and Enteroviral Infections.

Bitnun A, Yeh EA.

Curr Infect Dis Rep. 2018 Jun 29;20(9):34. doi: 10.1007/s11908-018-0641-x. Review.


Missed opportunities for prevention of vertical HIV transmission in Canada, 1997-2016: a surveillance study.

Bitnun A, Lee T, Brophy J, Samson LM, Kakkar F, Vaudry W, Tan B, Money DM, Singer J, Sauvé LJ, Alimenti A; Canadian Perinatal HIV Surveillance Program.

CMAJ Open. 2018 May 10;6(2):E202-E210. doi: 10.9778/cmajo.20180016.


Small bite, big problem: Understanding severe microcephaly in Canada.

Nelson CRM, Demarsh A, Miller SP, Morris SK, Moore Hepburn C, Bitnun A, Moore A, Shevell M, Evans J, Tataryn J.

Paediatr Child Health. 2017 Nov;22(8):504-505. doi: 10.1093/pch/pxx153. Epub 2017 Nov 27. No abstract available.


Childhood exposures to discarded needles and other objects potentially contaminated with blood-borne pathogens in Toronto, Canada.

Kordy F, Petrich A, Read SE, Bitnun A.

Paediatr Child Health. 2017 Oct;22(7):372-376. doi: 10.1093/pch/pxx110. Epub 2017 Sep 25.


Diagnosis and management of infants with congenital cytomegalovirus infection.

Gantt S, Bitnun A, Renaud C, Kakkar F, Vaudry W.

Paediatr Child Health. 2017 May;22(2):72-74. doi: 10.1093/pch/pxx002. Epub 2017 Apr 4.


An unexpected rash.

Khan S, Helmers A, Boggild AK, Keystone JS, Bitnun AS.

Paediatr Child Health. 2017 May;22(2):61-62. doi: 10.1093/pch/pxx035. Epub 2017 Apr 20. No abstract available.


Blood Mitochondrial DNA Content in HIV-Exposed Uninfected Children with Autism Spectrum Disorder.

Budd MA, Calli K, Samson L, Bowes J, Hsieh AYY, Forbes JC, Bitnun A, Singer J, Kakkar F, Alimenti A, Maan EJ, Lewis MES, Gentile C, Côté HCF, Brophy JC.

Viruses. 2018 Feb 11;10(2). pii: E77. doi: 10.3390/v10020077.


Immunogenicity and Safety of the Quadrivalent Human Papillomavirus Vaccine in Girls Living With HIV.

Brophy J, Bitnun A, Alimenti A, Lapointe N, Samson L, Read S, Karatzios C, Dobson S, Moses E, Blitz S, Lipsky NG, Ogilvie G, Walmsley S, Raboud J, Money D; HPV in HIV Study Group.

Pediatr Infect Dis J. 2018 Jun;37(6):595-597. doi: 10.1097/INF.0000000000001874.


Leukocyte Telomere Length at Birth and During the Early Life of Children Exposed to but Uninfected With HIV After In Utero Exposure to Antiretrovirals.

Ajaykumar A, Soudeyns H, Kakkar F, Brophy J, Bitnun A, Alimenti A, Albert AYK, Money DM, Côté HCF; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children.

J Infect Dis. 2018 Feb 14;217(5):710-720. doi: 10.1093/infdis/jix618.


Acute strongyloidiasis in a child recently returned from vacation in Cuba.

Alabi A, Boggild AK, Bitnun A.

CMAJ. 2017 Nov 20;189(46):E1416-E1420. doi: 10.1503/cmaj.170464. No abstract available.


The Epidemiology, Management, and Outcomes of Bacterial Meningitis in Infants.

Ouchenir L, Renaud C, Khan S, Bitnun A, Boisvert AA, McDonald J, Bowes J, Brophy J, Barton M, Ting J, Roberts A, Hawkes M, Robinson JL.

Pediatrics. 2017 Jul;140(1). pii: e20170476. doi: 10.1542/peds.2017-0476. Epub 2017 Jun 9.


Longitudinal development of cognitive, visuomotor and adaptive behavior skills in HIV uninfected children, aged 3-5 years of age, exposed pre- and perinatally to anti-retroviral medications.

Smith ML, Puka K, Sehra R, Read SE, Bitnun A.

AIDS Care. 2017 Oct;29(10):1302-1308. doi: 10.1080/09540121.2017.1325436. Epub 2017 May 8.


Mycobacterium Fortuitum Bloodstream Infection in a Very Low Birth Weight Preterm Neonate.

Hodgson K, Isabel S, McNamara P, Petrich A, Bitnun A.

Pediatr Infect Dis J. 2017 Aug;36(8):800-802. doi: 10.1097/INF.0000000000001592.


Longitudinal Outcomes in the 2014 Acute Flaccid Paralysis Cluster in Canada.

Yea C, Bitnun A, Robinson J, Mineyko A, Barton M, Mah JK, Vajsar J, Richardson S, Licht C, Brophy J, Crone M, Desai S, Hukin J, Jones K, Muir K, Pernica JM, Pless R, Pohl D, Rafay MF, Selby K, Venkateswaran S, Bernard G, Yeh EA.

J Child Neurol. 2017 Mar;32(3):301-307. doi: 10.1177/0883073816680770. Epub 2016 Dec 20.


Nevirapine Pharmacokinetics and Safety in Neonates Receiving Combination Antiretroviral Therapy for Prevention of Vertical HIV Transmission.

Lau E, Brophy J, Samson L, Kakkar F, Campbell DM, Yudin MH, Murphy K, Seto W, Colantonio D, Read SE, Bitnun A.

J Acquir Immune Defic Syndr. 2017 Apr 15;74(5):493-498. doi: 10.1097/QAI.0000000000001291.


HIV viral suppression results in higher antibody responses in HIV-positive women vaccinated with the quadrivalent human papillomavirus vaccine.

Money DM, Moses E, Blitz S, Vandriel SM, Lipsky N, Walmsley SL, Loutfy M, Trottier S, Smaill F, Yudin MH, Klein M, Harris M, Cohen J, Wobeser W, Bitnun A, Lapointe N, Samson L, Brophy J, Karatzios C, Ogilvie G, Coutlée F, Raboud J; HPV in HIV Study Group.

Vaccine. 2016 Sep 14;34(40):4799-806. doi: 10.1016/j.vaccine.2016.08.016. Epub 2016 Aug 17.


Safety of combination antiretroviral prophylaxis in high-risk HIV-exposed newborns: a retrospective review of the Canadian experience.

Kakkar FW, Samson L, Vaudry W, Brophy J, Le Meur JB, Lapointe N, Read SE, Bitnun A.

J Int AIDS Soc. 2016 Feb 12;19(1):20520. doi: 10.7448/IAS.19.1.20520. eCollection 2016.


Relating Tuberculosis (TB) Contact Characteristics to QuantiFERON-TB-Gold and Tuberculin Skin Test Results in the Toronto Pediatric TB Clinic.

Rose W, Read SE, Bitnun A, Rea E, Stephens D, Pongsamart W, Kitai I.

J Pediatric Infect Dis Soc. 2015 Jun;4(2):96-103. doi: 10.1093/jpids/piu024. Epub 2014 Apr 8.


Invasive Pneumococcal Disease Among Immunocompromised Persons: Implications for Vaccination Programs.

Shigayeva A, Rudnick W, Green K, Chen DK, Demczuk W, Gold WL, Johnstone J, Kitai I, Krajden S, Lovinsky R, Muller M, Powis J, Rau N, Walmsley S, Tyrrell G, Bitnun A, McGeer A; Toronto Invasive Bacterial Diseases Network.

Clin Infect Dis. 2016 Jan 15;62(2):139-47. doi: 10.1093/cid/civ803. Epub 2015 Sep 9.


Neurological Complications of PCR-Proven M. pneumoniae Infections in Children: Prodromal Illness Duration May Reflect Pathogenetic Mechanism.

Al-Zaidy SA, MacGregor D, Mahant S, Richardson SE, Bitnun A.

Clin Infect Dis. 2015 Oct 1;61(7):1092-8. doi: 10.1093/cid/civ473. Epub 2015 Jun 17.


Childhood encephalitis in Canada in 2015.

Bitnun A, Richardson SE.

Can J Infect Dis Med Microbiol. 2015 Mar-Apr;26(2):69-72. No abstract available.


Reply to Jackson.

Bloch KC, Bitnun A, Glaser CA, Mailles A, Stahl JP, Tunkel AR, Venkatesan A.

Clin Infect Dis. 2015 Jul 15;61(2):293-4. doi: 10.1093/cid/civ314. Epub 2015 Apr 21. No abstract available.


Identifying and treating group A streptococcal pharyngitis in children.

Science M, Bitnun A, McIsaac W.

CMAJ. 2015 Jan 6;187(1):13. doi: 10.1503/cmaj.141532. Epub 2014 Dec 15. No abstract available.


Medical nonadherence in pediatric HIV: psychosocial risks and intersection with the child protection system for medical neglect.

Azzopardi C, Wade M, Salter R, Macdougall G, Shouldice M, Read S, Bitnun A.

Child Abuse Negl. 2014 Nov;38(11):1766-77. doi: 10.1016/j.chiabu.2014.08.013. Epub 2014 Sep 26.


Quantiferon Gold-in-tube assay for TB screening in HIV infected children: influence of quantitative values.

Rose W, Kitai I, Kakkar F, Read SE, Behr MA, Bitnun A.

BMC Infect Dis. 2014 Sep 23;14:516. doi: 10.1186/1471-2334-14-516.


Ceftriaxone-induced immune hemolytic anemia.

Neuman G, Boodhan S, Wurman I, Koren G, Bitnun A, Kirby-Allen M, Ito S.

Ann Pharmacother. 2014 Dec;48(12):1594-604. doi: 10.1177/1060028014548310. Epub 2014 Aug 27. Erratum in: Ann Pharmacother. 2015 May;49(5):616.


Central nervous system complications of varicella-zoster virus.

Science M, MacGregor D, Richardson SE, Mahant S, Tran D, Bitnun A.

J Pediatr. 2014 Oct;165(4):779-85. doi: 10.1016/j.jpeds.2014.06.014. Epub 2014 Jul 22.


Early initiation of combination antiretroviral therapy in HIV-1-infected newborns can achieve sustained virologic suppression with low frequency of CD4+ T cells carrying HIV in peripheral blood.

Bitnun A, Samson L, Chun TW, Kakkar F, Brophy J, Murray D, Justement S, Soudeyns H, Ostrowski M, Mujib S, Harrigan PR, Kim J, Sandstrom P, Read SE.

Clin Infect Dis. 2014 Oct;59(7):1012-9. doi: 10.1093/cid/ciu432. Epub 2014 Jun 9.


Prevention of vertical HIV transmission and management of the HIV-exposed infant in Canada in 2014.

Bitnun A, Brophy J, Samson L, Alimenti A, Kakkar F, Lamarre V, Moore D, Karatzios C, Seigel S, Sauve L, Vaudry W, Yudin MH, Money D.

Can J Infect Dis Med Microbiol. 2014 Mar;25(2):75-7. No abstract available.


Delayed primary HHV-7 infection and neurologic disease.

Schwartz KL, Richardson SE, Ward KN, Donaldson C, MacGregor D, Banwell B, Mahant S, Bitnun A.

Pediatrics. 2014 Jun;133(6):e1541-7. doi: 10.1542/peds.2013-3344. Epub 2014 May 12.


Factors responsible for mother-to-child HIV transmission in Ontario, Canada, 1996-2008.

Lu D, Liu J, Samson L, Bitnun A, Seigel S, Brophy J, Leonard L, Remis RS.

Can J Public Health. 2014 Jan 6;105(1):e47-52.


Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium.

Venkatesan A, Tunkel AR, Bloch KC, Lauring AS, Sejvar J, Bitnun A, Stahl JP, Mailles A, Drebot M, Rupprecht CE, Yoder J, Cope JR, Wilson MR, Whitley RJ, Sullivan J, Granerod J, Jones C, Eastwood K, Ward KN, Durrheim DN, Solbrig MV, Guo-Dong L, Glaser CA; International Encephalitis Consortium.

Clin Infect Dis. 2013 Oct;57(8):1114-28. doi: 10.1093/cid/cit458. Epub 2013 Jul 15.


Point prevalence survey of antimicrobial utilization in the cardiac and pediatric critical care unit.

Blinova E, Lau E, Bitnun A, Cox P, Schwartz S, Atenafu E, Yau Y, Streitenberger L, Parshuram CS, Marshall J, Seto W.

Pediatr Crit Care Med. 2013 Jul;14(6):e280-8. doi: 10.1097/PCC.0b013e31828a846d.


Should a hospitalized child receive empiric treatment with acyclovir?

Kulik DM, Mekky M, Yang M, Bitnun A, Parkin PC.

Ital J Pediatr. 2012 Dec 17;38:72. doi: 10.1186/1824-7288-38-72.


Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.

Côté HC, Soudeyns H, Thorne A, Alimenti A, Lamarre V, Maan EJ, Sattha B, Singer J, Lapointe N, Money DM, Forbes J; CIHR Emerging Team in HIV therapy, aging (CARMA), Wong J, Bitnun A, Samson L, Brophy J, Burdge D, Pick N, van Schalkwyk J, Montaner J, Harris M, Janssen P.

PLoS One. 2012;7(7):e39266. doi: 10.1371/journal.pone.0039266. Epub 2012 Jul 16.


HIV mother-to-child transmission, mode of delivery, and duration of rupture of membranes: experience in the current era.

Mark S, Murphy KE, Read S, Bitnun A, Yudin MH.

Infect Dis Obstet Gynecol. 2012;2012:267969. doi: 10.1155/2012/267969. Epub 2012 May 28.


A national review of vertical HIV transmission.

Forbes JC, Alimenti AM, Singer J, Brophy JC, Bitnun A, Samson LM, Money DM, Lee TC, Lapointe ND, Read SE; Canadian Pediatric AIDS Research Group (CPARG).

AIDS. 2012 Mar 27;26(6):757-63. doi: 10.1097/QAD.0b013e328350995c.


Vitamin D supplementation and CD4 count in children infected with human immunodeficiency virus.

Kakalia S, Sochett EB, Stephens D, Assor E, Read SE, Bitnun A.

J Pediatr. 2011 Dec;159(6):951-7. doi: 10.1016/j.jpeds.2011.06.010. Epub 2011 Aug 4.


Mycoplasma pneumoniae: Innocent Bystander or a True Cause of Central Nervous System Disease?

Bitnun A, Richardson SE.

Curr Infect Dis Rep. 2010 Jul;12(4):282-90. doi: 10.1007/s11908-010-0105-4.


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