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Items: 34


MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection.

Arifuzzaman M, Mobley YR, Choi HW, Bist P, Salinas CA, Brown ZD, Chen SL, Staats HF, Abraham SN.

Sci Adv. 2019 Jan 2;5(1):eaav0216. doi: 10.1126/sciadv.aav0216. eCollection 2019 Jan.


Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium.

Miao Y, Bist P, Wu J, Zhao Q, Li QJ, Wan Y, Abraham SN.

Cell Host Microbe. 2017 Sep 13;22(3):330-342.e4. doi: 10.1016/j.chom.2017.08.002.


Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.

Bist P, Cheong WS, Ng A, Dikshit N, Kim BH, Pulloor NK, Khameneh HJ, Hedl M, Shenoy AR, Balamuralidhar V, Malik NBA, Hong M, Neutzner A, Chin KC, Kobayashi KS, Bertoletti A, Mortellaro A, Abraham C, MacMicking JD, Xavier RJ, Sukumaran B.

Nat Commun. 2017 Aug 18;8:16141. doi: 10.1038/ncomms16141.


E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.

Bist P, Cheong WS, Ng A, Dikshit N, Kim BH, Pulloor NK, Khameneh HJ, Hedl M, Shenoy AR, Balamuralidhar V, Malik NBA, Hong M, Neutzner A, Chin KC, Kobayashi KS, Bertoletti A, Mortellaro A, Abraham C, MacMicking JD, Xavier RJ, Sukumaran B.

Nat Commun. 2017 Jun 28;8:15865. doi: 10.1038/ncomms15865. Erratum in: Nat Commun. 2017 Aug 18;8:16141.


Dengue virus activates cGAS through the release of mitochondrial DNA.

Sun B, Sundström KB, Chew JJ, Bist P, Gan ES, Tan HC, Goh KC, Chawla T, Tang CK, Ooi EE.

Sci Rep. 2017 Jun 15;7(1):3594. doi: 10.1038/s41598-017-03932-1.


ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production.

Bist P, Kim SS, Pulloor NK, McCaffrey K, Nair SK, Liu Y, Lin R, Krishnan MN.

Mol Cell Biol. 2017 Mar 1;37(6). pii: e00537-16. doi: 10.1128/MCB.00537-16. Print 2017 Mar 15.


A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade.

Ningegowda R, Shivananju NS, Rajendran P, Basappa, Rangappa KS, Chinnathambi A, Li F, Achar RR, Shanmugam MK, Bist P, Alharbi SA, Lim LHK, Sethi G, Priya BS.

Apoptosis. 2017 Jan;22(1):145-157. doi: 10.1007/s10495-016-1312-8.


Influenza A virus enhances its propagation through the modulation of Annexin-A1 dependent endosomal trafficking and apoptosis.

Arora S, Lim W, Bist P, Perumalsamy R, Lukman HM, Li F, Welker LB, Yan B, Sethi G, Tambyah PA, Fairhurst AM, Alonso S, Lim LH.

Cell Death Differ. 2016 Jul;23(7):1243-56. doi: 10.1038/cdd.2016.19. Epub 2016 Mar 4.


Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells.

Dikshit N, Bist P, Fenlon SN, Pulloor NK, Chua CE, Scidmore MA, Carlyon JA, Tang BL, Chen SL, Sukumaran B.

PLoS Pathog. 2015 Aug 6;11(8):e1005083. doi: 10.1371/journal.ppat.1005083. eCollection 2015 Aug.


Annexin-A1 controls an ERK-RhoA-NFκB activation loop in breast cancer cells.

Bist P, Phua QH, Shu S, Yi Y, Anbalagan D, Lee LH, Sethi G, Low BC, Lim LH.

Biochem Biophys Res Commun. 2015 May 22;461(1):47-53. doi: 10.1016/j.bbrc.2015.03.166. Epub 2015 Apr 9.


Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.

Lee KG, Kim SS, Kui L, Voon DC, Mauduit M, Bist P, Bi X, Pereira NA, Liu C, Sukumaran B, Rénia L, Ito Y, Lam KP.

Cell Rep. 2015 Feb 24;10(7):1055-65. doi: 10.1016/j.celrep.2015.01.039. Epub 2015 Feb 19.


Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.

Anbalagan D, Yap G, Yuan Y, Pandey VK, Lau WH, Arora S, Bist P, Wong JS, Sethi G, Nissom PM, Lobie PE, Lim LH.

PLoS One. 2014 Dec 23;9(12):e114507. doi: 10.1371/journal.pone.0114507. eCollection 2014.


Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response.

Pulloor NK, Nair S, McCaffrey K, Kostic AD, Bist P, Weaver JD, Riley AM, Tyagi R, Uchil PD, York JD, Snyder SH, García-Sastre A, Potter BV, Lin R, Shears SB, Xavier RJ, Krishnan MN.

PLoS Pathog. 2014 Feb 27;10(2):e1003981. doi: 10.1371/journal.ppat.1003981. eCollection 2014 Feb. Erratum in: PLoS Pathog. 2014 Mar;10(3):e1004095. PLoS Pathog. 2014 Oct;10(10):e1004519. McCaffrey, Kathleen [added].


The Nod1, Nod2, and Rip2 axis contributes to host immune defense against intracellular Acinetobacter baumannii infection.

Bist P, Dikshit N, Koh TH, Mortellaro A, Tan TT, Sukumaran B.

Infect Immun. 2014 Mar;82(3):1112-22. doi: 10.1128/IAI.01459-13. Epub 2013 Dec 23.


Annexin-A1 regulates TLR-mediated IFN-β production through an interaction with TANK-binding kinase 1.

Bist P, Shu S, Lee H, Arora S, Nair S, Lim JY, Dayalan J, Gasser S, Biswas SK, Fairhurst AM, Lim LH.

J Immunol. 2013 Oct 15;191(8):4375-82. doi: 10.4049/jimmunol.1301504. Epub 2013 Sep 18.


Scrub typhus with sepsis and acute respiratory distress syndrome.

Kurup A, Issac A, Loh JP, Lee TB, Chua R, Bist P, Chao CC, Lewis M, Gubler DJ, Ching WM, Ooi EE, Sukumaran B.

J Clin Microbiol. 2013 Aug;51(8):2787-90. doi: 10.1128/JCM.00463-13. Epub 2013 Jun 12.


Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma.

Manu KA, Shanmugam MK, Ong TH, Subramaniam A, Siveen KS, Perumal E, Samy RP, Bist P, Lim LH, Kumar AP, Hui KM, Sethi G.

PLoS One. 2013;8(3):e57015. doi: 10.1371/journal.pone.0057015. Epub 2013 Mar 5.


Annexin-1-deficient mice exhibit spontaneous airway hyperresponsiveness and exacerbated allergen-specific antibody responses in a mouse model of asthma.

Ng FS, Wong KY, Guan SP, Mustafa FB, Kajiji TS, Bist P, Biswas SK, Wong WS, Lim LH.

Clin Exp Allergy. 2011 Dec;41(12):1793-803. doi: 10.1111/j.1365-2222.2011.03855.x. Epub 2011 Sep 20.


Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4.

Manu KA, Shanmugam MK, Rajendran P, Li F, Ramachandran L, Hay HS, Kannaiyan R, Swamy SN, Vali S, Kapoor S, Ramesh B, Bist P, Koay ES, Lim LH, Ahn KS, Kumar AP, Sethi G.

Mol Cancer. 2011 Sep 1;10:107. doi: 10.1186/1476-4598-10-107.


Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model.

Shanmugam MK, Manu KA, Ong TH, Ramachandran L, Surana R, Bist P, Lim LH, Kumar AP, Hui KM, Sethi G.

Int J Cancer. 2011 Oct 1;129(7):1552-63. doi: 10.1002/ijc.26120. Epub 2011 Jul 20.


Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis.

Bist P, Leow SC, Phua QH, Shu S, Zhuang Q, Loh WT, Nguyen TH, Zhou JB, Hooi SC, Lim LH.

Oncogene. 2011 Jul 14;30(28):3174-85. doi: 10.1038/onc.2011.28. Epub 2011 Mar 7.


Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells.

Chua AW, Hay HS, Rajendran P, Shanmugam MK, Li F, Bist P, Koay ES, Lim LH, Kumar AP, Sethi G.

Biochem Pharmacol. 2010 Nov 15;80(10):1553-62. doi: 10.1016/j.bcp.2010.07.045. Epub 2010 Aug 10. Erratum in: Biochem Pharmacol. 2014 Jun 15;89(4):557-8.


Tumor suppressor SMAR1 represses IkappaBalpha expression and inhibits p65 transactivation through matrix attachment regions.

Singh K, Sinha S, Malonia SK, Bist P, Tergaonkar V, Chattopadhyay S.

J Biol Chem. 2009 Jan 9;284(2):1267-78. doi: 10.1074/jbc.M801088200. Epub 2008 Nov 3.


Nutlin-3 inhibits the NFkappaB pathway in a p53-dependent manner: implications in lung cancer therapy.

Dey A, Wong ET, Bist P, Tergaonkar V, Lane DP.

Cell Cycle. 2007 Sep 1;6(17):2178-85. Epub 2007 Jun 27.


Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance.

Biswas SK, Bist P, Dhillon MK, Kajiji T, Del Fresno C, Yamamoto M, Lopez-Collazo E, Akira S, Tergaonkar V.

J Immunol. 2007 Sep 15;179(6):4083-92.


A mutation in the Mod subunit of EcoP15I restriction enzyme converts the DNA methyltransferase to a site-specific endonuclease.

Bist P, Madhusoodanan UK, Rao DN.

J Biol Chem. 2007 Feb 9;282(6):3520-30. Epub 2006 Dec 4.


Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival.

Ghosh S, Tergaonkar V, Rothlin CV, Correa RG, Bottero V, Bist P, Verma IM, Hunter T.

Cancer Cell. 2006 Sep;10(3):215-26.


Integrity of GH-loop of foot-and-mouth disease virus during virus inactivation: detection by epitope specific antibodies.

Patil PK, Suryanarayana V, Bist P, Bayry J, Natarajan C.

Vaccine. 2002 Jan 15;20(7-8):1163-8.


S-adenosyl-L-methionine is required for DNA cleavage by type III restriction enzymes.

Bist P, Sistla S, Krishnamurthy V, Acharya A, Chandrakala B, Rao DN.

J Mol Biol. 2001 Jun 29;310(1):93-109.


E. coli expressed proteins as diagnostic reagents for typing of foot-and-mouth disease virus.

Suryanarayana VV, Viswanathan S, Ratish G, Bist P, Prabhudas K, Gajendragad MR, Natarajan C.

Arch Virol. 1999;144(9):1701-12.


Immuno affinity purification of foot and mouth disease virus type specific antibodies using recombinant protein adsorbed to polystyrene wells.

Bayry J, Prabhudas K, Bist P, Reddy GR, Suryanarayana VV.

J Virol Methods. 1999 Aug;81(1-2):21-30.


Serotyping of foot-and-mouth disease virus by antigen capture reverse transcriptase/polymerase chain reaction.

Suryanarayana V, Madanamohan B, Bist P, Natarajan C, Tratschin JD.

J Virol Methods. 1999 Jun;80(1):45-52. Erratum in: J Virol Methods 1999 Dec;83(1-2):193.


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