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Items: 1 to 50 of 129

1.

Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances.

Ohradanova-Repic A, Machacek C, Charvet C, Lager F, Le Roux D, Platzer R, Leksa V, Mitulovic G, Burkard TR, Zlabinger GJ, Fischer MB, Feuillet V, Renault G, Blüml S, Benko M, Suchanek M, Huppa JB, Matsuyama T, Cavaco-Paulo A, Bismuth G, Stockinger H.

Front Immunol. 2018 Apr 27;9:852. doi: 10.3389/fimmu.2018.00852. eCollection 2018.

2.

Paxillin Binding to the Cytoplasmic Domain of CD103 Promotes Cell Adhesion and Effector Functions for CD8+ Resident Memory T Cells in Tumors.

Gauthier L, Corgnac S, Boutet M, Gros G, Validire P, Bismuth G, Mami-Chouaib F.

Cancer Res. 2017 Dec 15;77(24):7072-7082. doi: 10.1158/0008-5472.CAN-17-1487. Epub 2017 Oct 11.

PMID:
29021139
3.

FAM65B controls the proliferation of transformed and primary T cells.

Froehlich J, Versapuech M, Megrelis L, Largeteau Q, Meunier S, Tanchot C, Bismuth G, Delon J, Mangeney M.

Oncotarget. 2016 Sep 27;7(39):63215-63225. doi: 10.18632/oncotarget.11438.

4.

Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice.

Nogueira E, Lager F, Le Roux D, Nogueira P, Freitas J, Charvet C, Renault G, Loureiro A, Almeida CR, Ohradanova-Repic A, Machacek C, Bernardes GJ, Moreira A, Stockinger H, Burnet M, Carmo AM, Gomes AC, Preto A, Bismuth G, Cavaco-Paulo A.

J Biomed Nanotechnol. 2015 Dec;11(12):2243-52.

PMID:
26510317
5.

Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORγt-Th17 Program.

Lainé A, Martin B, Luka M, Mir L, Auffray C, Lucas B, Bismuth G, Charvet C.

J Immunol. 2015 Aug 15;195(4):1791-803. doi: 10.4049/jimmunol.1500849. Epub 2015 Jul 13.

6.

Src-family-tyrosine kinase Lyn is critical for TLR2-mediated NF-κB activation through the PI 3-kinase signaling pathway.

Toubiana J, Rossi AL, Belaidouni N, Grimaldi D, Pene F, Chafey P, Comba B, Camoin L, Bismuth G, Claessens YE, Mira JP, Chiche JD.

Innate Immun. 2015 Oct;21(7):685-97. doi: 10.1177/1753425915586075. Epub 2015 Jun 8.

PMID:
26055819
7.

Shaping mycolactone for therapeutic use against inflammatory disorders.

Guenin-Macé L, Baron L, Chany AC, Tresse C, Saint-Auret S, Jönsson F, Le Chevalier F, Bruhns P, Bismuth G, Hidalgo-Lucas S, Bisson JF, Blanchard N, Demangel C.

Sci Transl Med. 2015 May 27;7(289):289ra85. doi: 10.1126/scitranslmed.aab0458.

8.

Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo.

Clement M, Fornasa G, Loyau S, Morvan M, Andreata F, Guedj K, Khallou-Laschet J, Larghi P, Le Roux D, Bismuth G, Chiocchia G, Hivroz C, Newman DK, Nicoletti A, Caligiuri G.

J Autoimmun. 2015 Jan;56:23-33. doi: 10.1016/j.jaut.2014.09.002. Epub 2014 Sep 30.

PMID:
25277651
9.

Smad and NFAT pathways cooperate to induce CD103 expression in human CD8 T lymphocytes.

Mokrani M, Klibi J, Bluteau D, Bismuth G, Mami-Chouaib F.

J Immunol. 2014 Mar 1;192(5):2471-9. doi: 10.4049/jimmunol.1302192. Epub 2014 Jan 29.

10.

T-cell modulatory properties of CD5 and its role in antitumor immune responses.

Tabbekh M, Mokrani-Hammani M, Bismuth G, Mami-Chouaib F.

Oncoimmunology. 2013 Jan 1;2(1):e22841.

11.

Fam65b is a new transcriptional target of FOXO1 that regulates RhoA signaling for T lymphocyte migration.

Rougerie P, Largeteau Q, Megrelis L, Carrette F, Lejeune T, Toffali L, Rossi B, Zeghouf M, Cherfils J, Constantin G, Laudanna C, Bismuth G, Mangeney M, Delon J.

J Immunol. 2013 Jan 15;190(2):748-55. doi: 10.4049/jimmunol.1201174. Epub 2012 Dec 14.

12.

Antigen stored in dendritic cells after macropinocytosis is released unprocessed from late endosomes to target B cells.

Le Roux D, Le Bon A, Dumas A, Taleb K, Sachse M, Sikora R, Julithe M, Benmerah A, Bismuth G, Niedergang F.

Blood. 2012 Jan 5;119(1):95-105. doi: 10.1182/blood-2011-02-336123. Epub 2011 Nov 2.

13.

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation.

Oliveira MI, Gonçalves CM, Pinto M, Fabre S, Santos AM, Lee SF, Castro MA, Nunes RJ, Barbosa RR, Parnes JR, Yu C, Davis SJ, Moreira A, Bismuth G, Carmo AM.

Eur J Immunol. 2012 Jan;42(1):195-205. doi: 10.1002/eji.201040528. Epub 2011 Nov 28.

14.

Evidence for internal stores of CCR5 in blood cells.

Shirvani H, Achour L, Scott MG, Thuret A, Labbé-Jullié C, Bismuth G, Marullo S.

Blood. 2011 Jul 28;118(4):1175-6. doi: 10.1182/blood-2011-02-330886. No abstract available.

15.

Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression.

Guenin-Macé L, Carrette F, Asperti-Boursin F, Le Bon A, Caleechurn L, Di Bartolo V, Fontanet A, Bismuth G, Demangel C.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12833-8. doi: 10.1073/pnas.1016496108. Epub 2011 Jul 18.

16.

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia.

Chapuis N, Park S, Leotoing L, Tamburini J, Verdier F, Bardet V, Green AS, Willems L, Agou F, Ifrah N, Dreyfus F, Bismuth G, Baud V, Lacombe C, Mayeux P, Bouscary D.

Blood. 2010 Nov 18;116(20):4240-50. doi: 10.1182/blood-2009-12-260711. Epub 2010 Jul 29.

17.

[Twinkling artifact on Doppler US: clinical presentations].

Hassani H, Brasseur A, Raynal G, Texier A, Demuynck F, Bismuth G, Saidi L.

J Radiol. 2010 May;91(5 Pt 1):539-42. French.

18.

HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway.

Fausther-Bovendo H, Vieillard V, Sagan S, Bismuth G, Debré P.

PLoS Pathog. 2010 Jul 1;6:e1000975. doi: 10.1371/journal.ppat.1000975.

19.

[Answer to March e-quid. Pulmonary langerhans cell histiocytosis].

Hassani H, Bouaziz R, Bismuth G, Li Thiao Te V, Bastier AL, Cordonnier C, Pautard B.

J Radiol. 2010 Apr;91(4):518-20. French. No abstract available.

20.

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.

Boulkroun S, Guenin-Macé L, Thoulouze MI, Monot M, Merckx A, Langsley G, Bismuth G, Di Bartolo V, Demangel C.

J Immunol. 2010 Feb 1;184(3):1436-44. doi: 10.4049/jimmunol.0902854. Epub 2009 Dec 30.

21.

Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn.

Brignatz C, Paronetto MP, Opi S, Cappellari M, Audebert S, Feuillet V, Bismuth G, Roche S, Arold ST, Sette C, Collette Y.

Mol Cell Biol. 2009 Dec;29(24):6438-48. doi: 10.1128/MCB.00398-09. Epub 2009 Oct 5.

22.

SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.

Wang H, Wei B, Bismuth G, Rudd CE.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12436-41. doi: 10.1073/pnas.0900510106. Epub 2009 Jul 15.

23.

Fine tuning the immune response with PI3K.

Fruman DA, Bismuth G.

Immunol Rev. 2009 Mar;228(1):253-72. doi: 10.1111/j.1600-065X.2008.00750.x. Review.

PMID:
19290933
24.

FOXO1, T-cell trafficking and immune responses.

Carrette F, Fabre S, Bismuth G.

Adv Exp Med Biol. 2009;665:3-16. Review.

PMID:
20429412
25.

CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.

Achour L, Scott MG, Shirvani H, Thuret A, Bismuth G, Labbé-Jullié C, Marullo S.

Blood. 2009 Feb 26;113(9):1938-47. doi: 10.1182/blood-2008-02-141275. Epub 2008 Dec 8.

26.

FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase.

Fabre S, Carrette F, Chen J, Lang V, Semichon M, Denoyelle C, Lazar V, Cagnard N, Dubart-Kupperschmitt A, Mangeney M, Fruman DA, Bismuth G.

J Immunol. 2008 Sep 1;181(5):2980-9.

27.

Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation.

Lasserre R, Guo XJ, Conchonaud F, Hamon Y, Hawchar O, Bernard AM, Soudja SM, Lenne PF, Rigneault H, Olive D, Bismuth G, Nunès JA, Payrastre B, Marguet D, He HT.

Nat Chem Biol. 2008 Sep;4(9):538-47. doi: 10.1038/nchembio.103. Epub 2008 Jul 20.

PMID:
18641634
28.

ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse.

Fos C, Salles A, Lang V, Carrette F, Audebert S, Pastor S, Ghiotto M, Olive D, Bismuth G, Nunès JA.

J Immunol. 2008 Aug 1;181(3):1969-77.

29.

Two opposite signaling outputs are driven by the KIR2DL1 receptor in human CD4+ T cells.

Fourmentraux-Neves E, Jalil A, Da Rocha S, Pichon C, Chouaib S, Bismuth G, Caignard A.

Blood. 2008 Sep 15;112(6):2381-9. doi: 10.1182/blood-2007-12-127779. Epub 2008 Jun 23.

30.

Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2.

Nunes RJ, Castro MA, Gonçalves CM, Bamberger M, Pereira CF, Bismuth G, Carmo AM.

J Immunol. 2008 Jan 15;180(2):988-97. Erratum in: J Immunol. 2008 Mar 1;180(5):3613.

31.

CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization.

Schneider H, Smith X, Liu H, Bismuth G, Rudd CE.

Eur J Immunol. 2008 Jan;38(1):40-7.

32.

Human CD5 protects circulating tumor antigen-specific CTL from tumor-mediated activation-induced cell death.

Friedlein G, El Hage F, Vergnon I, Richon C, Saulnier P, Lécluse Y, Caignard A, Boumsell L, Bismuth G, Chouaib S, Mami-Chouaib F.

J Immunol. 2007 Jun 1;178(11):6821-7.

33.

CCR7 ligands control basal T cell motility within lymph node slices in a phosphoinositide 3-kinase-independent manner.

Asperti-Boursin F, Real E, Bismuth G, Trautmann A, Donnadieu E.

J Exp Med. 2007 May 14;204(5):1167-79. Epub 2007 May 7.

34.

Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse.

Castro MA, Oliveira MI, Nunes RJ, Fabre S, Barbosa R, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM.

J Immunol. 2007 Apr 1;178(7):4351-61.

35.

Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis.

Le Floc'h A, Jalil A, Vergnon I, Le Maux Chansac B, Lazar V, Bismuth G, Chouaib S, Mami-Chouaib F.

J Exp Med. 2007 Mar 19;204(3):559-70. Epub 2007 Feb 26.

36.

[PI3-kinase: Linking immunological synapse to T-cell proliferation].

Fabre S, Lang V, Bismuth G.

Med Sci (Paris). 2006 Oct;22(10):872-7. Review. French.

37.

[The immunological synapse: models facing facts].

Bismuth G, Trautmann A.

Med Sci (Paris). 2006 Aug-Sep;22(8-9):721-6. Review. French.

38.

PI3-kinase and the control of T cell growth and proliferation by FoxOs.

Fabre S, Lang V, Bismuth G.

Bull Cancer. 2006 May;93(5):E36-8.

39.

Cyclosporin-A inhibits ERK phosphorylation in B cells by modulating the binding of Raf protein to Bcl2.

Gary-Gouy H, Sainz-Perez A, Bismuth G, Ghadiri A, Perrino BA, Dalloul A.

Biochem Biophys Res Commun. 2006 May 26;344(1):134-9.

PMID:
16630579
40.

Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure.

Abouzahr S, Bismuth G, Gaudin C, Caroll O, Van Endert P, Jalil A, Dausset J, Vergnon I, Richon C, Kauffmann A, Galon J, Raposo G, Mami-Chouaib F, Chouaib S.

Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1428-33. Epub 2006 Jan 23.

41.
42.

Multiple survival signals are delivered by dendritic cells to naive CD4+ T cells.

Feuillet V, Lucas B, Di Santo JP, Bismuth G, Trautmann A.

Eur J Immunol. 2005 Sep;35(9):2563-72.

43.

In situ sensory adaptation of tumor-infiltrating T lymphocytes to peptide-MHC levels elicits strong antitumor reactivity.

Dorothée G, Vergnon I, El Hage F, Le Maux Chansac B, Ferrand V, Lécluse Y, Opolon P, Chouaib S, Bismuth G, Mami-Chouaib F.

J Immunol. 2005 Jun 1;174(11):6888-97.

44.

Biochemical and HIV-1 coreceptor properties of K26R, a new CCR5 Variant in China's Sichuan population.

Ma L, Dudoit Y, Tran T, Xing H, Chen J, Pancino G, Bismuth G, Debré P, Shao Y, Theodorou I, Capoulade-Métay C.

J Acquir Immune Defic Syndr. 2005 May 1;39(1):38-43.

PMID:
15851912
45.

Stable activation of phosphatidylinositol 3-kinase in the T cell immunological synapse stimulates Akt signaling to FoxO1 nuclear exclusion and cell growth control.

Fabre S, Lang V, Harriague J, Jobart A, Unterman TG, Trautmann A, Bismuth G.

J Immunol. 2005 Apr 1;174(7):4161-71.

46.

Immunological synapses are versatile structures enabling selective T cell polarization.

Depoil D, Zaru R, Guiraud M, Chauveau A, Harriague J, Bismuth G, Utzny C, Müller S, Valitutti S.

Immunity. 2005 Feb;22(2):185-94.

47.

New CCR5 variants associated with reduced HIV coreceptor function in southeast Asia.

Capoulade-Métay C, Ma L, Truong LX, Dudoit Y, Versmisse P, Nguyen NV, Nguyen M, Scott-Algara D, Barré-Sinoussi F, Debré P, Bismuth G, Pancino G, Theodorou I.

AIDS. 2004 Nov 19;18(17):2243-52.

PMID:
15577536
48.

Tetraspanin CD82 controls the association of cholesterol-dependent microdomains with the actin cytoskeleton in T lymphocytes: relevance to co-stimulation.

Delaguillaumie A, Harriague J, Kohanna S, Bismuth G, Rubinstein E, Seigneuret M, Conjeaud H.

J Cell Sci. 2004 Oct 15;117(Pt 22):5269-82. Epub 2004 Sep 28.

49.

Tec kinase migrates to the T cell-APC interface independently of its pleckstrin homology domain.

Garçon F, Bismuth G, Isnardon D, Olive D, Nunès JA.

J Immunol. 2004 Jul 15;173(2):770-5.

50.

ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation.

Faure S, Salazar-Fontana LI, Semichon M, Tybulewicz VL, Bismuth G, Trautmann A, Germain RN, Delon J.

Nat Immunol. 2004 Mar;5(3):272-9. Epub 2004 Feb 1.

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