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Items: 1 to 50 of 75

1.

Establishing MALDI-TOF as Versatile Drug Discovery Readout to Dissect the PTP1B Enzymatic Reaction.

Winter M, Bretschneider T, Kleiner C, Ries R, Hehn JP, Redemann N, Luippold AH, Bischoff D, Büttner FH.

SLAS Discov. 2018 Jul;23(6):561-573. doi: 10.1177/2472555218759267. Epub 2018 Feb 21.

PMID:
29466676
2.

Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes.

Schaefer M, Morinaga G, Matsui A, Schänzle G, Bischoff D, Süssmuth RD.

Drug Metab Dispos. 2018 Feb;46(2):166-177. doi: 10.1124/dmd.117.078238. Epub 2017 Dec 6.

PMID:
29212823
3.

Nonmineralized and Mineralized Collagen Scaffolds Induce Differential Osteogenic Signaling Pathways in Human Mesenchymal Stem Cells.

Zhou Q, Ren X, Bischoff D, Weisgerber DW, Yamaguchi DT, Miller TA, Harley BAC, Lee JC.

Adv Healthc Mater. 2017 Dec;6(23). doi: 10.1002/adhm.201700641. Epub 2017 Sep 25.

4.

Ultrafast and Predictive Mass Spectrometry-Based Autotaxin Assays for Label-Free Potency Screening.

Bretschneider T, Luippold AH, Romig H, Bischoff D, Klinder K, Nicklin P, Rist W.

SLAS Discov. 2017 Apr;22(4):425-432. doi: 10.1177/2472555217690484. Epub 2017 Feb 2.

PMID:
28328321
5.

Metabolic relationship between diabetes and Alzheimer's Disease affected by Cyclo(His-Pro) plus zinc treatment.

Song MK, Bischoff DS, Song AM, Uyemura K, Yamaguchi DT.

BBA Clin. 2016 Oct 2;7:41-54. doi: 10.1016/j.bbacli.2016.09.003. eCollection 2017 Jun. Review.

6.

Nanoparticulate Mineralized Collagen Scaffolds and BMP-9 Induce a Long-Term Bone Cartilage Construct in Human Mesenchymal Stem Cells.

Ren X, Weisgerber DW, Bischoff D, Lewis MS, Reid RR, He TC, Yamaguchi DT, Miller TA, Harley BA, Lee JC.

Adv Healthc Mater. 2016 Jul;5(14):1821-30. doi: 10.1002/adhm.201600187. Epub 2016 Jun 8.

7.

BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.

Lamb DJ, Wollin SL, Schnapp A, Bischoff D, Erb KJ, Bouyssou T, Guilliard B, Strasser C, Wex E, Blum S, Thaler E, Nickel H, Radmacher O, Haas H, Swantek JL, Souza D, Canfield M, White D, Panzenbeck M, Kashem MA, Sanville-Ross M, Kono T, Sewald K, Braun A, Obernolte H, Danov O, Schaenzle G, Rast G, Maier GM, Hoffmann M.

J Pharmacol Exp Ther. 2016 Jun;357(3):554-61. doi: 10.1124/jpet.116.233155. Epub 2016 Apr 5.

8.

Nanoparticulate mineralized collagen scaffolds induce in vivo bone regeneration independent of progenitor cell loading or exogenous growth factor stimulation.

Ren X, Tu V, Bischoff D, Weisgerber DW, Lewis MS, Yamaguchi DT, Miller TA, Harley BA, Lee JC.

Biomaterials. 2016 May;89:67-78. doi: 10.1016/j.biomaterials.2016.02.020. Epub 2016 Feb 18.

9.

Induction of CXC chemokines in human mesenchymal stem cells by stimulation with secreted frizzled-related proteins through non-canonical Wnt signaling.

Bischoff DS, Zhu JH, Makhijani NS, Yamaguchi DT.

World J Stem Cells. 2015 Dec 26;7(11):1262-73. doi: 10.4252/wjsc.v7.i11.1262.

10.

Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds.

Schaefer M, Schänzle G, Bischoff D, Süssmuth RD.

Drug Metab Dispos. 2016 Mar;44(3):435-44. doi: 10.1124/dmd.115.067348. Epub 2015 Dec 28.

11.

Micro-CT in the Assessment of Pediatric Renal Osteodystrophy by Bone Histomorphometry.

Pereira RC, Bischoff DS, Yamaguchi D, Salusky IB, Wesseling-Perry K.

Clin J Am Soc Nephrol. 2016 Mar 7;11(3):481-7. doi: 10.2215/CJN.04810515. Epub 2015 Dec 28.

12.

Measurement Back-Action in Stacked Graphene Quantum Dots.

Bischoff D, Eich M, Zilberberg O, Rössler C, Ihn T, Ensslin K.

Nano Lett. 2015 Sep 9;15(9):6003-8. doi: 10.1021/acs.nanolett.5b02167. Epub 2015 Aug 20.

PMID:
26280388
13.

Optimizing Collagen Scaffolds for Bone Engineering: Effects of Cross-linking and Mineral Content on Structural Contraction and Osteogenesis.

Lee JC, Pereira CT, Ren X, Huang W, Bischoff D, Weisgerber DW, Yamaguchi DT, Harley BA, Miller TA.

J Craniofac Surg. 2015 Sep;26(6):1992-6. doi: 10.1097/SCS.0000000000001918.

14.

Osteogenesis on nanoparticulate mineralized collagen scaffolds via autogenous activation of the canonical BMP receptor signaling pathway.

Ren X, Bischoff D, Weisgerber DW, Lewis MS, Tu V, Yamaguchi DT, Miller TA, Harley BA, Lee JC.

Biomaterials. 2015 May;50:107-14. doi: 10.1016/j.biomaterials.2015.01.059. Epub 2015 Feb 17.

15.

Anomalous sequence of quantum Hall liquids revealing a tunable Lifshitz transition in bilayer graphene.

Varlet A, Bischoff D, Simonet P, Watanabe K, Taniguchi T, Ihn T, Ensslin K, Mucha-Kruczyński M, Fal'ko VI.

Phys Rev Lett. 2014 Sep 12;113(11):116602. Epub 2014 Sep 9.

PMID:
25259994
16.

Fabry-Pérot interference in gapped bilayer graphene with broken anti-Klein tunneling.

Varlet A, Liu MH, Krueckl V, Bischoff D, Simonet P, Watanabe K, Taniguchi T, Richter K, Ensslin K, Ihn T.

Phys Rev Lett. 2014 Sep 12;113(11):116601. Epub 2014 Sep 8.

PMID:
25259993
17.

Ultrasmooth metallic foils for growth of high quality graphene by chemical vapor deposition.

Procházka P, Mach J, Bischoff D, Lišková Z, Dvořák P, Vaňatka M, Simonet P, Varlet A, Hemzal D, Petrenec M, Kalina L, Bartošík M, Ensslin K, Varga P, Čechal J, Šikola T.

Nanotechnology. 2014 May 9;25(18):185601. doi: 10.1088/0957-4484/25/18/185601. Epub 2014 Apr 16.

PMID:
24739598
18.

Constitutive expression of human telomerase enhances the proliferation potential of human mesenchymal stem cells.

Bischoff DS, Makhijani NS, Yamaguchi DT.

Biores Open Access. 2012 Dec;1(6):273-9. doi: 10.1089/biores.2012.0252.

19.
20.

S-Glucuronidation of 7-mercapto-4-methylcoumarin by human UDP glycosyltransferases in genetically engineered fission yeast cells.

Buchheit D, Schmitt EI, Bischoff D, Ebner T, Bureik M.

Biol Chem. 2011 Dec;392(12):1089-95. doi: 10.1515/BC.2011.194.

PMID:
22050224
21.

In vitro mineralization of human mesenchymal stem cells on three-dimensional type I collagen versus PLGA scaffolds: a comparative analysis.

Kruger EA, Im DD, Bischoff DS, Pereira CT, Huang W, Rudkin GH, Yamaguchi DT, Miller TA.

Plast Reconstr Surg. 2011 Jun;127(6):2301-11. doi: 10.1097/PRS.0b013e318213a004.

PMID:
21617464
22.

Pharmacokinetics and metabolism of BIBF 1120 after oral dosing to healthy male volunteers.

Stopfer P, Rathgen K, Bischoff D, Lüdtke S, Marzin K, Kaiser R, Wagner K, Ebner T.

Xenobiotica. 2011 Apr;41(4):297-311. doi: 10.3109/00498254.2010.545452. Epub 2011 Jan 4.

PMID:
21204634
23.

Challenges and solutions to metabolites in safety testing: impact of the International Conference on Harmonization M3(R2) guidance.

Yu H, Bischoff D, Tweedie D.

Expert Opin Drug Metab Toxicol. 2010 Dec;6(12):1539-49. doi: 10.1517/17425255.2010.530655. Epub 2010 Nov 11. Review.

PMID:
21067462
24.

CXC receptor knockout mice: characterization of skeletal features and membranous bone healing in the adult mouse.

Bischoff DS, Sakamoto T, Ishida K, Makhijani NS, Gruber HE, Yamaguchi DT.

Bone. 2011 Feb;48(2):267-74. doi: 10.1016/j.bone.2010.09.026. Epub 2010 Sep 24.

PMID:
20870046
25.

Glucuronide production by whole-cell biotransformation using genetically engineered fission yeast Schizosaccharomyces pombe.

Drăgan CA, Buchheit D, Bischoff D, Ebner T, Bureik M.

Drug Metab Dispos. 2010 Mar;38(3):509-15. doi: 10.1124/dmd.109.030965. Epub 2009 Dec 11.

26.

Effects of strength training with eccentric overload on muscle adaptation in male athletes.

Friedmann-Bette B, Bauer T, Kinscherf R, Vorwald S, Klute K, Bischoff D, Müller H, Weber MA, Metz J, Kauczor HU, Bärtsch P, Billeter R.

Eur J Appl Physiol. 2010 Mar;108(4):821-36. doi: 10.1007/s00421-009-1292-2. Epub 2009 Nov 25.

PMID:
19937450
27.

Estimating glutathione synthesis with deuterated water: a model for peptide biosynthesis.

Cabral CB, Bullock KH, Bischoff DJ, Tompkins RG, Yu YM, Kelleher JK.

Anal Biochem. 2008 Aug 1;379(1):40-4. doi: 10.1016/j.ab.2008.04.042. Epub 2008 Apr 29.

28.

Pretreatment of poly(l-lactide-co-glycolide) scaffolds with sodium hydroxide enhances osteoblastic differentiation and slows proliferation of mouse preosteoblast cells.

Carpizo KH, Saran MJ, Huang W, Ishida K, Roostaeian J, Bischoff D, Huang CK, Rudkin GH, Yamaguchi DT, Miller TA.

Plast Reconstr Surg. 2008 Feb;121(2):424-34. doi: 10.1097/01.prs.0000298366.74273.da.

PMID:
18300958
30.

Angiogenic CXC chemokine expression during differentiation of human mesenchymal stem cells towards the osteoblastic lineage.

Bischoff DS, Zhu JH, Makhijani NS, Kumar A, Yamaguchi DT.

J Cell Biochem. 2008 Feb 15;103(3):812-24.

PMID:
17583554
31.

Genetic analysis of the balhimycin (vancomycin-type) oxygenase genes.

Stegmann E, Pelzer S, Bischoff D, Puk O, Stockert S, Butz D, Zerbe K, Robinson J, Süssmuth RD, Wohlleben W.

J Biotechnol. 2006 Aug 5;124(4):640-53. Epub 2006 May 30.

PMID:
16730832
32.

The biosynthesis of vancomycin-type glycopeptide antibiotics--a model for oxidative side-chain cross-linking by oxygenases coupled to the action of peptide synthetases.

Bischoff D, Bister B, Bertazzo M, Pfeifer V, Stegmann E, Nicholson GJ, Keller S, Pelzer S, Wohlleben W, Süssmuth RD.

Chembiochem. 2005 Feb;6(2):267-72. No abstract available.

PMID:
15651041
33.

Precursor-directed biosynthesis for the generation of novel glycopetides.

Stegmann E, Bischoff D, Kittel C, Pelzer S, Puk O, Recktenwald J, Weist S, Süssmuth R, Wohlleben W.

Ernst Schering Res Found Workshop. 2005;(51):215-32. Review. No abstract available.

PMID:
15645723
34.

KC chemokine expression by TGF-beta in C3H10T1/2 cells induced towards osteoblasts.

Bischoff DS, Zhu JH, Makhijani NS, Yamaguchi DT.

Biochem Biophys Res Commun. 2005 Jan 14;326(2):364-70.

PMID:
15582587
35.

Regulation of proliferation and migration in retinoic acid treated C3H10T1/2 cells by TGF-beta isoforms.

Makhijani NS, Bischoff DS, Yamaguchi DT.

J Cell Physiol. 2005 Jan;202(1):304-13.

PMID:
15389595
36.

Evaluation of balhimycin as a chiral selector for enantioresolution by capillary electrophoresis.

Jiang Z, Kang J, Bischoff D, Bister B, Süssmuth RD, Schurig V.

Electrophoresis. 2004 Aug;25(16):2687-92.

PMID:
15351999
37.

Biosynthesis of chloro-beta-hydroxytyrosine, a nonproteinogenic amino acid of the peptidic backbone of glycopeptide antibiotics.

Puk O, Bischoff D, Kittel C, Pelzer S, Weist S, Stegmann E, Süssmuth RD, Wohlleben W.

J Bacteriol. 2004 Sep;186(18):6093-100.

38.

The structure of salmochelins: C-glucosylated enterobactins of Salmonella enterica.

Bister B, Bischoff D, Nicholson GJ, Valdebenito M, Schneider K, Winkelmann G, Hantke K, Süssmuth RD.

Biometals. 2004 Aug;17(4):471-81.

PMID:
15259369
39.

Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032.

Riedlinger J, Reicke A, Zähner H, Krismer B, Bull AT, Maldonado LA, Ward AC, Goodfellow M, Bister B, Bischoff D, Süssmuth RD, Fiedler HP.

J Antibiot (Tokyo). 2004 Apr;57(4):271-9.

40.

Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine.

Weist S, Kittel C, Bischoff D, Bister B, Pfeifer V, Nicholson GJ, Wohlleben W, Süssmuth RD.

J Am Chem Soc. 2004 May 19;126(19):5942-3.

PMID:
15137740
41.

Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway.

Bister B, Bischoff D, Ströbele M, Riedlinger J, Reicke A, Wolter F, Bull AT, Zähner H, Fiedler HP, Süssmuth RD.

Angew Chem Int Ed Engl. 2004 May 3;43(19):2574-6. No abstract available.

PMID:
15127456
42.
43.

Bromobalhimycin and chlorobromobalhimycins--illuminating the potential of halogenases in glycopeptide antibiotic biosyntheses.

Bister B, Bischoff D, Nicholson GJ, Stockert S, Wink J, Brunati C, Donadio S, Pelzer S, Wohlleben W, Süssmuth RD.

Chembiochem. 2003 Jul 7;4(7):658-62. No abstract available.

PMID:
12851938
44.

Oscillapeptin J, a new grazer toxin of the freshwater cyanobacterium Planktothrix rubescens.

Blom JF, Bister B, Bischoff D, Nicholson G, Jung G, Süssmuth RD, Jüttner F.

J Nat Prod. 2003 Mar;66(3):431-4.

PMID:
12662108
46.

Fluorobalhimycin--a new chapter in glycopeptide antibiotic research.

Weist S, Bister B, Puk O, Bischoff D, Pelzer S, Nicholson GJ, Wohlleben W, Jung G, Süssmuth RD.

Angew Chem Int Ed Engl. 2002 Sep 16;41(18):3383-5. No abstract available.

PMID:
12298039
47.

Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis.

Zerbe K, Pylypenko O, Vitali F, Zhang W, Rouset S, Heck M, Vrijbloed JW, Bischoff D, Bister B, Süssmuth RD, Pelzer S, Wohlleben W, Robinson JA, Schlichting I.

J Biol Chem. 2002 Dec 6;277(49):47476-85. Epub 2002 Aug 30.

48.

Glycopeptide biosynthesis in Amycolatopsis mediterranei DSM5908: function of a halogenase and a haloperoxidase/perhydrolase.

Puk O, Huber P, Bischoff D, Recktenwald J, Jung G, Süssmuth RD, van Pée KH, Wohlleben W, Pelzer S.

Chem Biol. 2002 Feb;9(2):225-35.

49.

Both Lymantria dispar nucleopolyhedrovirus enhancin genes contribute to viral potency.

Popham HJ, Bischoff DS, Slavicek JM.

J Virol. 2001 Sep;75(18):8639-48.

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