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Items: 1 to 50 of 92


Irreversible oxidative post-translational modifications in heart disease.

Tomin T, Schittmayer M, Honeder S, Heininger C, Birner-Gruenberger R.

Expert Rev Proteomics. 2019 Aug;16(8):681-693. doi: 10.1080/14789450.2019.1645602. Epub 2019 Jul 30.


Endothelial lipase increases antioxidative capacity of high-density lipoprotein.

Schilcher I, Ledinski G, Radulović S, Hallström S, Eichmann T, Madl T, Zhang F, Leitinger G, Kolb-Lenz D, Darnhofer B, Birner-Gruenberger R, Wadsack C, Kratky D, Marsche G, Frank S, Cvirn G.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1363-1374. doi: 10.1016/j.bbalip.2019.06.011. Epub 2019 Jun 17.


Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.

Kolleritsch S, Kien B, Schoiswohl G, Diwoky C, Schreiber R, Heier C, Maresch LK, Schweiger M, Eichmann TO, Stryeck S, Krenn P, Tomin T, Kolb D, Rülicke T, Hoefler G, Wolinski H, Madl T, Birner-Gruenberger R, Haemmerle G.

Cardiovasc Res. 2019 May 6. pii: cvz119. doi: 10.1093/cvr/cvz119. [Epub ahead of print]


Proteomic Analysis of Vocal Fold Fibroblasts Exposed to Cigarette Smoke Extract: Exploring the Pathophysiology of Reinke's Edema.

Gugatschka M, Darnhofer B, Grossmann T, Schittmayer M, Hortobagyi D, Kirsch A, Karpf E, Brcic L, Birner-Gruenberger R, Karbiener M.

Mol Cell Proteomics. 2019 Aug;18(8):1511-1525. doi: 10.1074/mcp.RA119.001272. Epub 2019 May 22.


Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME.

Rössler I, Embacher J, Pillet B, Murat G, Liesinger L, Hafner J, Unterluggauer JJ, Birner-Gruenberger R, Kressler D, Pertschy B.

Nucleic Acids Res. 2019 Jul 26;47(13):6984-7002. doi: 10.1093/nar/gkz317.


Olfactory cleft proteome does not reflect olfactory performance in patients with idiopathic and postinfectious olfactory disorder: A pilot study.

Wolf A, Liesinger L, Spoerk S, Schittmayer M, Lang-Loidolt D, Birner-Gruenberger R, Tomazic PV.

Sci Rep. 2018 Dec 3;8(1):17554. doi: 10.1038/s41598-018-35776-8.


High density lipoprotein cholesterol and proteome in SR-B1 KO mice: lost in precipitation.

Contreras-Duarte S, Santander N, Birner-Gruenberger R, Wadsack C, Rigotti A, Busso D.

J Transl Med. 2018 Nov 12;16(1):309. doi: 10.1186/s12967-018-1683-4.


Characterization of a lipid droplet protein from Yarrowia lipolytica that is required for its oleaginous phenotype.

Bhutada G, Kavšček M, Hofer F, Gogg-Fassolter G, Schweiger M, Darnhofer B, Kordiš D, Birner-Gruenberger R, Natter K.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1193-1205. doi: 10.1016/j.bbalip.2018.07.010. Epub 2018 Jul 25.


Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc.

Fuchs R, Stracke A, Holzmann V, Luschin-Ebengreuth G, Meier-Allard N, Ebner N, Lassacher TM, Absenger-Novak M, Fröhlich E, Schittmayer M, Cano Crespo S, Palacin M, Rinner B, Birner-Gruenberger R.

Biochim Biophys Acta Mol Cell Res. 2018 Sep;1865(9):1211-1229. doi: 10.1016/j.bbamcr.2018.06.006. Epub 2018 Jun 15.


A Semi-Rationally Engineered Bacterial Pyrrolysyl-tRNA Synthetase Genetically Encodes Phenyl Azide Chemistry.

Fladischer P, Weingartner A, Blamauer J, Darnhofer B, Birner-Gruenberger R, Kardashliev T, Ruff AJ, Schwaneberg U, Wiltschi B.

Biotechnol J. 2019 Mar;14(3):e1800125. doi: 10.1002/biot.201800125. Epub 2018 Jun 11.


Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.

Tobola F, Lelimousin M, Varrot A, Gillon E, Darnhofer B, Blixt O, Birner-Gruenberger R, Imberty A, Wiltschi B.

ACS Chem Biol. 2018 Aug 17;13(8):2211-2219. doi: 10.1021/acschembio.8b00377. Epub 2018 Jun 12.


Quantification of Cellular Folate Species by LC-MS after Stabilization by Derivatization.

Schittmayer M, Birner-Gruenberger R, Zamboni N.

Anal Chem. 2018 Jun 19;90(12):7349-7356. doi: 10.1021/acs.analchem.8b00650. Epub 2018 Jun 5.


Myristic acid induces proteomic and secretomic changes associated with steatosis, cytoskeleton remodeling, endoplasmic reticulum stress, protein turnover and exosome release in HepG2 cells.

Speziali G, Liesinger L, Gindlhuber J, Leopold C, Pucher B, Brandi J, Castagna A, Tomin T, Krenn P, Thallinger GG, Olivieri O, Martinelli N, Kratky D, Schittmayer M, Birner-Gruenberger R, Cecconi D.

J Proteomics. 2018 Jun 15;181:118-130. doi: 10.1016/j.jprot.2018.04.008. Epub 2018 Apr 12.


Elevated Cardiac Troponin T in Patients With Skeletal Myopathies.

Schmid J, Liesinger L, Birner-Gruenberger R, Stojakovic T, Scharnagl H, Dieplinger B, Asslaber M, Radl R, Beer M, Polacin M, Mair J, Szolar D, Berghold A, Quasthoff S, Binder JS, Rainer PP.

J Am Coll Cardiol. 2018 Apr 10;71(14):1540-1549. doi: 10.1016/j.jacc.2018.01.070.


Comparison of tear proteome in allergic rhinoconjunctivitis patients and controls with respect to pollen season.

Tomazic PV, Liesinger L, Pucher B, Thallinger GG, Leitner A, Spoerk S, Gerstenberger C, Lang-Loidolt D, Birner-Gruenberger R.

Allergy. 2018 Jul;73(7):1541-1543. doi: 10.1111/all.13444. Epub 2018 Apr 15. No abstract available.


Deletion of Adipose Triglyceride Lipase Links Triacylglycerol Accumulation to a More-Aggressive Phenotype in A549 Lung Carcinoma Cells.

Tomin T, Fritz K, Gindlhuber J, Waldherr L, Pucher B, Thallinger GG, Nomura DK, Schittmayer M, Birner-Gruenberger R.

J Proteome Res. 2018 Apr 6;17(4):1415-1425. doi: 10.1021/acs.jproteome.7b00782. Epub 2018 Mar 7.


Proteomics and phosphoproteomics analysis of liver in male rats exposed to bisphenol A: Mechanism of hepatotoxicity and biomarker discovery.

Vahdati Hassani F, Abnous K, Mehri S, Jafarian A, Birner-Gruenberger R, Yazdian Robati R, Hosseinzadeh H.

Food Chem Toxicol. 2018 Feb;112:26-38. doi: 10.1016/j.fct.2017.12.021. Epub 2017 Dec 18.


Resolution Ladder for High-Resolution Mass Spectrometry.

Schittmayer M, Birner-Gruenberger R.

Anal Chem. 2017 Sep 19;89(18):9611-9615. doi: 10.1021/acs.analchem.7b02042. Epub 2017 Sep 1.


Integrative metabolomics as emerging tool to study autophagy regulation.

Stryeck S, Birner-Gruenberger R, Madl T.

Microb Cell. 2017 Jul 13;4(8):240-258. doi: 10.15698/mic2017.08.584. Review.


Protective effect of crocin on BPA-induced liver toxicity in rats through inhibition of oxidative stress and downregulation of MAPK and MAPKAP signaling pathway and miRNA-122 expression.

Vahdati Hassani F, Mehri S, Abnous K, Birner-Gruenberger R, Hosseinzadeh H.

Food Chem Toxicol. 2017 Sep;107(Pt A):395-405. doi: 10.1016/j.fct.2017.07.007. Epub 2017 Jul 6.


APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.

Pessentheiner AR, Huber K, Pelzmann HJ, Prokesch A, Radner FPW, Wolinski H, Lindroos-Christensen J, Hoefler G, Rülicke T, Birner-Gruenberger R, Bilban M, Bogner-Strauss JG.

FASEB J. 2017 Sep;31(9):4088-4103. doi: 10.1096/fj.201601337R. Epub 2017 May 30.


Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily.

Lanfranchi E, Pavkov-Keller T, Koehler EM, Diepold M, Steiner K, Darnhofer B, Hartler J, Bergh TVD, Joosten HJ, Gruber-Khadjawi M, Thallinger GG, Birner-Gruenberger R, Gruber K, Winkler M, Glieder A.

Sci Rep. 2017 May 26;7:46834. doi: 10.1038/srep46834.


Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily.

Lanfranchi E, Pavkov-Keller T, Koehler EM, Diepold M, Steiner K, Darnhofer B, Hartler J, Van Den Bergh T, Joosten HJ, Gruber-Khadjawi M, Thallinger GG, Birner-Gruenberger R, Gruber K, Winkler M, Glieder A.

Sci Rep. 2017 May 3;7:46738. doi: 10.1038/srep46738. Erratum in: Sci Rep. 2017 May 26;7:46834.


Comparative proteomics of paired vocal fold and oral mucosa fibroblasts.

Karbiener M, Darnhofer B, Frisch MT, Rinner B, Birner-Gruenberger R, Gugatschka M.

J Proteomics. 2017 Feb 23;155:11-21. doi: 10.1016/j.jprot.2017.01.010. Epub 2017 Jan 15.


PpEst is a novel PBAT degrading polyesterase identified by proteomic screening of Pseudomonas pseudoalcaligenes.

Wallace PW, Haernvall K, Ribitsch D, Zitzenbacher S, Schittmayer M, Steinkellner G, Gruber K, Guebitz GM, Birner-Gruenberger R.

Appl Microbiol Biotechnol. 2017 Mar;101(6):2291-2303. doi: 10.1007/s00253-016-7992-8. Epub 2016 Nov 21.


Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1.

Mitterer V, Gantenbein N, Birner-Gruenberger R, Murat G, Bergler H, Kressler D, Pertschy B.

Sci Rep. 2016 Nov 7;6:36714. doi: 10.1038/srep36714.


Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris.

Krainer FW, Gerstmann MA, Darnhofer B, Birner-Gruenberger R, Glieder A.

J Biotechnol. 2016 Sep 10;233:181-9. doi: 10.1016/j.jbiotec.2016.07.012. Epub 2016 Jul 16.


Pichia pastoris mutants as host strains for efficient secretion of recombinant branched chain aminotransferase (BCAT).

Weinhandl K, Ballach M, Winkler M, Ahmad M, Glieder A, Birner-Gruenberger R, Fotheringham I, Escalettes F, Camattari A.

J Biotechnol. 2016 Oct 10;235:84-91. doi: 10.1016/j.jbiotec.2016.06.004. Epub 2016 Jun 7.


Tracking Protein S-Fatty Acylation with Proteomics.

Birner-Gruenberger R, Breinbauer R.

Chembiochem. 2016 Aug 17;17(16):1488-90. doi: 10.1002/cbic.201600314. Epub 2016 Jul 8.


Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.

Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D.

Diabetologia. 2016 Aug;59(8):1743-52. doi: 10.1007/s00125-016-3968-6. Epub 2016 May 6.


Liver disease alters high-density lipoprotein composition, metabolism and function.

Trieb M, Horvath A, Birner-Gruenberger R, Spindelboeck W, Stadlbauer V, Taschler U, Curcic S, Stauber RE, Holzer M, Pasterk L, Heinemann A, Marsche G.

Biochim Biophys Acta. 2016 Jul;1861(7):630-8. doi: 10.1016/j.bbalip.2016.04.013. Epub 2016 Apr 19.


Refined Pichia pastoris reference genome sequence.

Sturmberger L, Chappell T, Geier M, Krainer F, Day KJ, Vide U, Trstenjak S, Schiefer A, Richardson T, Soriaga L, Darnhofer B, Birner-Gruenberger R, Glick BS, Tolstorukov I, Cregg J, Madden K, Glieder A.

J Biotechnol. 2016 Oct 10;235:121-31. doi: 10.1016/j.jbiotec.2016.04.023. Epub 2016 Apr 12. Review.


Structures of almond hydroxynitrile lyase isoenzyme 5 provide a rationale for the lack of oxidoreductase activity in flavin dependent HNLs.

Pavkov-Keller T, Bakhuis J, Steinkellner G, Jolink F, Keijmel E, Birner-Gruenberger R, Gruber K.

J Biotechnol. 2016 Oct 10;235:24-31. doi: 10.1016/j.jbiotec.2016.04.013. Epub 2016 Apr 8. Review.


N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.

Prokesch A, Pelzmann HJ, Pessentheiner AR, Huber K, Madreiter-Sokolowski CT, Drougard A, Schittmayer M, Kolb D, Magnes C, Trausinger G, Graier WF, Birner-Gruenberger R, Pospisilik JA, Bogner-Strauss JG.

Sci Rep. 2016 Apr 5;6:23723. doi: 10.1038/srep23723.


Cleaning out the Litterbox of Proteomic Scientists' Favorite Pet: Optimized Data Analysis Avoiding Trypsin Artifacts.

Schittmayer M, Fritz K, Liesinger L, Griss J, Birner-Gruenberger R.

J Proteome Res. 2016 Apr 1;15(4):1222-9. doi: 10.1021/acs.jproteome.5b01105. Epub 2016 Mar 22.


Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.

Aschauer P, Rengachari S, Lichtenegger J, Schittmayer M, Das KM, Mayer N, Breinbauer R, Birner-Gruenberger R, Gruber CC, Zimmermann R, Gruber K, Oberer M.

Biochim Biophys Acta. 2016 May;1861(5):462-70. doi: 10.1016/j.bbalip.2016.02.005. Epub 2016 Feb 9.


Seasonal proteome changes of nasal mucus reflect perennial inflammatory response and reduced defence mechanisms and plasticity in allergic rhinitis.

Tomazic PV, Birner-Gruenberger R, Leitner A, Spoerk S, Lang-Loidolt D.

J Proteomics. 2016 Feb 5;133:153-160. doi: 10.1016/j.jprot.2015.12.021. Epub 2015 Dec 28.


Synergism of proteomics and mRNA sequencing for enzyme discovery.

Sturmberger L, Wallace PW, Glieder A, Birner-Gruenberger R.

J Biotechnol. 2016 Oct 10;235:132-8. doi: 10.1016/j.jbiotec.2015.12.015. Epub 2015 Dec 18. Review.


Recombinant production of a peroxidase-protein G fusion protein in Pichia pastoris.

Krainer FW, Darnhofer B, Birner-Gruenberger R, Glieder A.

J Biotechnol. 2016 Feb 10;219:24-7. doi: 10.1016/j.jbiotec.2015.12.020. Epub 2015 Dec 18.


The cytotoxicity of the α1-adrenoceptor antagonist prazosin is linked to an endocytotic mechanism equivalent to transport-P.

Fuchs R, Stracke A, Ebner N, Zeller CW, Raninger AM, Schittmayer M, Kueznik T, Absenger-Novak M, Birner-Gruenberger R.

Toxicology. 2015 Dec 2;338:17-29. doi: 10.1016/j.tox.2015.09.008. Epub 2015 Oct 9.


Gel-free mass spectrometry analysis of Drosophila melanogaster heads.

Aradska J, Bulat T, Sialana FJ, Birner-Gruenberger R, Erich B, Lubec G.

Proteomics. 2015 Oct;15(19):3356-60. doi: 10.1002/pmic.201500092. Epub 2015 Sep 10.


Weighing the proteasome for covalent modifications.

Birner-Gruenberger R, Breinbauer R.

Chem Biol. 2015 Mar 19;22(3):315-6. doi: 10.1016/j.chembiol.2015.03.003.


Phosphoryl transfer from α-d-glucose 1-phosphate catalyzed by Escherichia coli sugar-phosphate phosphatases of two protein superfamily types.

Wildberger P, Pfeiffer M, Brecker L, Rechberger GN, Birner-Gruenberger R, Nidetzky B.

Appl Environ Microbiol. 2015 Mar;81(5):1559-72. doi: 10.1128/AEM.03314-14. Epub 2014 Dec 19.


CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization.

Sahu-Osen A, Montero-Moran G, Schittmayer M, Fritz K, Dinh A, Chang YF, McMahon D, Boeszoermenyi A, Cornaciu I, Russell D, Oberer M, Carman GM, Birner-Gruenberger R, Brasaemle DL.

J Lipid Res. 2015 Jan;56(1):109-21. doi: 10.1194/jlr.M055004. Epub 2014 Nov 24.


Apolipoproteins have a potential role in nasal mucus of allergic rhinitis patients: a proteomic study.

Tomazic PV, Birner-Gruenberger R, Leitner A, Darnhofer B, Spoerk S, Lang-Loidolt D.

Laryngoscope. 2015 Mar;125(3):E91-6. doi: 10.1002/lary.25003. Epub 2014 Nov 1.


Structure of the double-stranded DNA-binding type IV secretion protein TraN from Enterococcus.

Goessweiner-Mohr N, Eder M, Hofer G, Fercher C, Arends K, Birner-Gruenberger R, Grohmann E, Keller W.

Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2376-89. doi: 10.1107/S1399004714014187. Epub 2014 Aug 29.


Gestational diabetes mellitus modulates neonatal high-density lipoprotein composition and its functional heterogeneity.

Sreckovic I, Birner-Gruenberger R, Besenboeck C, Miljkovic M, Stojakovic T, Scharnagl H, Marsche G, Lang U, Kotur-Stevuljevic J, Jelic-Ivanovic Z, Desoye G, Wadsack C.

Biochim Biophys Acta. 2014 Nov;1841(11):1619-27. doi: 10.1016/j.bbalip.2014.07.021. Epub 2014 Aug 12.


Understanding high-density lipoprotein function in disease: recent advances in proteomics unravel the complexity of its composition and biology.

Birner-Gruenberger R, Schittmayer M, Holzer M, Marsche G.

Prog Lipid Res. 2014 Oct;56:36-46. doi: 10.1016/j.plipres.2014.07.003. Epub 2014 Aug 6. Review.


Gel-based mass spectrometric analysis of hippocampal transmembrane proteins using high resolution LTQ Orbitrap Velos Pro.

Heo S, Spoerk S, Birner-Gruenberger R, Lubec G.

Proteomics. 2014 Sep;14(17-18):2084-8. doi: 10.1002/pmic.201400077. Epub 2014 Aug 13.


The type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold.

Goessweiner-Mohr N, Fercher C, Arends K, Birner-Gruenberger R, Laverde-Gomez D, Huebner J, Grohmann E, Keller W.

Acta Crystallogr D Biol Crystallogr. 2014 Apr;70(Pt 4):1124-35. doi: 10.1107/S1399004714001606. Epub 2014 Mar 21.


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