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Items: 1 to 50 of 201

1.

Quantitative evidence for early metastatic seeding in colorectal cancer.

Hu Z, Ding J, Ma Z, Sun R, Seoane JA, Scott Shaffer J, Suarez CJ, Berghoff AS, Cremolini C, Falcone A, Loupakis F, Birner P, Preusser M, Lenz HJ, Curtis C.

Nat Genet. 2019 Jul;51(7):1113-1122. doi: 10.1038/s41588-019-0423-x. Epub 2019 Jun 17.

PMID:
31209394
2.

Interrelations of Sphingolipid and Lysophosphatidate Signaling with Immune System in Ovarian Cancer.

Meshcheryakova A, Svoboda M, Jaritz M, Mungenast F, Salzmann M, Pils D, Cacsire Castillo-Tong D, Hager G, Wolf A, Braicu EI, Sehouli J, Lambrechts S, Vergote I, Mahner S, Birner P, Zimmermann P, Brindley DN, Heinze G, Zeillinger R, Mechtcheriakova D.

Comput Struct Biotechnol J. 2019 Apr 10;17:537-560. doi: 10.1016/j.csbj.2019.04.004. eCollection 2019.

3.

High-risk Mucosal Human Papillomavirus Infection in Squamous Cell Carcinoma and Bowen's Disease of the Hand.

Dorfer S, Kancz S, Birner P, Strasser K, Kirnbauer R, Petzelbauer P, Radakovic S, Harpain L, Pehamberger H, Thalhammer F, Handisurya A.

Acta Derm Venereol. 2019 Apr 1;99(4):462-463. doi: 10.2340/00015555-3115. No abstract available.

4.

Mutational profile of colorectal cancer lung metastases and paired primary tumors by targeted next generation sequencing: implications on clinical outcome after surgery.

Schweiger T, Liebmann-Reindl S, Glueck O, Starlinger P, Laengle J, Birner P, Klepetko W, Pils D, Streubel B, Hoetzenecker K.

J Thorac Dis. 2018 Nov;10(11):6147-6157. doi: 10.21037/jtd.2018.10.72.

5.

High correlation of temporal muscle thickness with lumbar skeletal muscle cross-sectional area in patients with brain metastases.

Leitner J, Pelster S, Schöpf V, Berghoff AS, Woitek R, Asenbaum U, Nenning KH, Widhalm G, Kiesel B, Gatterbauer B, Dieckmann K, Birner P, Prayer D, Preusser M, Furtner J.

PLoS One. 2018 Nov 29;13(11):e0207849. doi: 10.1371/journal.pone.0207849. eCollection 2018.

6.

Combination of isocitrate dehydrogenase 1 (IDH1) mutation and podoplanin expression in brain tumors identifies patients at high or low risk of venous thromboembolism.

Mir Seyed Nazari P, Riedl J, Preusser M, Posch F, Thaler J, Marosi C, Birner P, Ricken G, Hainfellner JA, Pabinger I, Ay C.

J Thromb Haemost. 2018 Jun;16(6):1121-1127. doi: 10.1111/jth.14129. Epub 2018 May 20.

7.

Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro.

Hong J, Fristiohady A, Nguyen CH, Milovanovic D, Huttary N, Krieger S, Hong J, Geleff S, Birner P, Jäger W, Özmen A, Krenn L, Krupitza G.

Front Pharmacol. 2018 Mar 14;9:220. doi: 10.3389/fphar.2018.00220. eCollection 2018.

8.

Correlation of trastuzumab-based treatment with clinical characteristics and prognosis in HER2-positive gastric and gastroesophageal junction cancer: A retrospective single center analysis.

Ilhan-Mutlu A, Taghizadeh H, Beer A, Dolak W, Ba-Ssalamah A, Schoppmann SF, Hejna M, Birner P, Preusser M.

Cancer Biol Ther. 2018 Mar 4;19(3):169-174. doi: 10.1080/15384047.2017.1414759. Epub 2018 Jan 17.

9.

HER2 and TOP2A Gene Amplification and Protein Expression in Upper Tract Urothelial Carcinomas.

Aumayr K, Klatte T, Neudert B, Birner P, Shariat S, Schmidinger M, Susani M, Haitel A.

Pathol Oncol Res. 2018 Jul;24(3):575-581. doi: 10.1007/s12253-017-0260-0. Epub 2017 Jul 28.

PMID:
28755093
10.

Next-Generation Sequencing-based genomic profiling of brain metastases of primary ovarian cancer identifies high number of BRCA-mutations.

Balendran S, Liebmann-Reindl S, Berghoff AS, Reischer T, Popitsch N, Geier CB, Kenner L, Birner P, Streubel B, Preusser M.

J Neurooncol. 2017 Jul;133(3):469-476. doi: 10.1007/s11060-017-2459-z. Epub 2017 May 11.

11.

Decreased body mass index is associated with impaired survival in lung cancer patients with brain metastases: A retrospective analysis of 624 patients.

Masel EK, Berghoff AS, Füreder LM, Heicappell P, Schlieter F, Widhalm G, Gatterbauer B, Dieckmann U, Birner P, Bartsch R, Schur S, Watzke HH, Zielinski CC, Preusser M.

Eur J Cancer Care (Engl). 2017 Nov;26(6). doi: 10.1111/ecc.12707. Epub 2017 May 10.

PMID:
28488812
12.

Combining standard clinical blood values for improving survival prediction in patients with newly diagnosed brain metastases-development and validation of the LabBM score.

Berghoff AS, Wolpert F, Holland-Letz T, Koller R, Widhalm G, Gatterbauer B, Dieckmann K, Birner P, Bartsch R, Zielinski CC, Weller M, Preusser M.

Neuro Oncol. 2017 Sep 1;19(9):1255-1262. doi: 10.1093/neuonc/now290.

13.

Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism.

Riedl J, Preusser M, Nazari PM, Posch F, Panzer S, Marosi C, Birner P, Thaler J, Brostjan C, Lötsch D, Berger W, Hainfellner JA, Pabinger I, Ay C.

Blood. 2017 Mar 30;129(13):1831-1839. doi: 10.1182/blood-2016-06-720714. Epub 2017 Jan 10.

14.

Survival prediction using temporal muscle thickness measurements on cranial magnetic resonance images in patients with newly diagnosed brain metastases.

Furtner J, Berghoff AS, Albtoush OM, Woitek R, Asenbaum U, Prayer D, Widhalm G, Gatterbauer B, Dieckmann K, Birner P, Aretin B, Bartsch R, Zielinski CC, Schöpf V, Preusser M.

Eur Radiol. 2017 Aug;27(8):3167-3173. doi: 10.1007/s00330-016-4707-6. Epub 2017 Jan 3.

15.

Molecular pathology of cancer: how to communicate with disease.

Birner P, Prager G, Streubel B.

ESMO Open. 2016 Nov 17;1(5):e000085. eCollection 2016. Review.

16.

Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients.

Proestling K, Birner P, Balendran S, Nirtl N, Marton E, Yerlikaya G, Kuessel L, Reischer T, Wenzl R, Streubel B, Husslein H.

Reprod Biol Endocrinol. 2016 Nov 24;14(1):81.

17.

Descriptive statistical analysis of a real life cohort of 2419 patients with brain metastases of solid cancers.

Berghoff AS, Schur S, Füreder LM, Gatterbauer B, Dieckmann K, Widhalm G, Hainfellner J, Zielinski CC, Birner P, Bartsch R, Preusser M.

ESMO Open. 2016 Mar 16;1(2):e000024. eCollection 2016.

18.

Tumor infiltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC).

Berghoff AS, Ricken G, Wilhelm D, Rajky O, Widhalm G, Dieckmann K, Birner P, Bartsch R, Preusser M.

J Neurooncol. 2016 Oct;130(1):19-29. Epub 2016 Jul 19.

PMID:
27436101
19.

Comprehensive study of angiogenic factors in women with endometriosis compared to women without endometriosis.

Yerlikaya G, Balendran S, Pröstling K, Reischer T, Birner P, Wenzl R, Kuessel L, Streubel B, Husslein H.

Eur J Obstet Gynecol Reprod Biol. 2016 Sep;204:88-98. doi: 10.1016/j.ejogrb.2016.07.500. Epub 2016 Aug 3.

PMID:
27541444
20.

AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer.

Svoboda M, Meshcheryakova A, Heinze G, Jaritz M, Pils D, Castillo-Tong DC, Hager G, Thalhammer T, Jensen-Jarolim E, Birner P, Braicu I, Sehouli J, Lambrechts S, Vergote I, Mahner S, Zimmermann P, Zeillinger R, Mechtcheriakova D.

BMC Genomics. 2016 Aug 16;17(1):643. doi: 10.1186/s12864-016-3001-y.

21.

Tumor-infiltrating lymphocyte subsets and tertiary lymphoid structures in pulmonary metastases from colorectal cancer.

Schweiger T, Berghoff AS, Glogner C, Glueck O, Rajky O, Traxler D, Birner P, Preusser M, Klepetko W, Hoetzenecker K.

Clin Exp Metastasis. 2016 Oct;33(7):727-39. doi: 10.1007/s10585-016-9813-y. Epub 2016 Jul 23.

22.

The Lymphatic Phenotype of Lung Allografts in Patients With Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome.

Traxler D, Schweiger T, Schwarz S, Schuster MM, Jaksch P, Lang G, Birner P, Klepetko W, Ankersmit HJ, Hoetzenecker K.

Transplantation. 2017 Feb;101(2):310-315. doi: 10.1097/TP.0000000000001263.

PMID:
27163544
23.

Lymphovascular invasion of tumor cells in lymph node metastases has a negative impact on survival in esophageal cancer.

Schiefer AI, Schoppmann SF, Birner P.

Surgery. 2016 Aug;160(2):331-40. doi: 10.1016/j.surg.2016.02.034. Epub 2016 Apr 14.

PMID:
27085684
24.

Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.

Berghoff AS, Fuchs E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K, Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J, Preusser M.

Oncoimmunology. 2015 Jun 9;5(1):e1057388. eCollection 2016.

25.

Multicenter Evaluation of a Novel Automated Rapid Detection System of BRAF Status in Formalin-Fixed, Paraffin-Embedded Tissues.

Schiefer AI, Parlow L, Gabler L, Mesteri I, Koperek O, von Deimling A, Streubel B, Preusser M, Lehmann A, Kellner U, Pauwels P, Lambin S, Dietel M, Hummel M, Klauschen F, Birner P, Möbs M.

J Mol Diagn. 2016 May;18(3):370-377. doi: 10.1016/j.jmoldx.2015.12.005. Epub 2016 Feb 24.

PMID:
26921540
26.

Interleukin-6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosus.

Birner P, Heider S, Petzelbauer P, Wolf P, Kornauth C, Kuroll M, Merkel O, Steiner G, Kishimoto T, Rose-John S, Soleiman A, Moriggl R, Kenner L.

Exp Dermatol. 2016 Apr;25(4):305-10. doi: 10.1111/exd.12934. Epub 2016 Feb 13. Erratum in: Exp Dermatol. 2017 May;26(5):467.

27.

Evaluation of Polo-like kinase 1 as a potential therapeutic target in Merkel cell carcinoma.

Kadletz L, Bigenzahn J, Thurnher D, Stanisz I, Erovic BM, Schneider S, Schmid R, Seemann R, Birner P, Heiduschka G.

Head Neck. 2016 Apr;38 Suppl 1:E1918-25. doi: 10.1002/hed.24349. Epub 2015 Dec 29.

PMID:
26713885
28.

Genetic variants associated with colorectal brain metastases susceptibility and survival.

Stremitzer S, Berghoff AS, Volz NB, Zhang W, Yang D, Stintzing S, Ning Y, Sunakawa Y, Yamauchi S, Sebio A, Matsusaka S, Okazaki S, Hanna D, Parekh A, Mendez A, Berger MD, El-Khoueiry R, Birner P, Preusser M, Lenz HJ.

Pharmacogenomics J. 2017 Jan;17(1):29-35. doi: 10.1038/tpj.2015.86. Epub 2015 Dec 22.

PMID:
26689941
29.

MicroRNA Profiles of Barrett's Esophagus and Esophageal Adenocarcinoma: Differences in Glandular Non-native Epithelium.

Drahos J, Schwameis K, Orzolek LD, Hao H, Birner P, Taylor PR, Pfeiffer RM, Schoppmann SF, Cook MB.

Cancer Epidemiol Biomarkers Prev. 2016 Mar;25(3):429-37. doi: 10.1158/1055-9965.EPI-15-0161. Epub 2015 Nov 24.

30.

BRAF inhibitors in BRAF-V600 mutated primary neuroepithelial brain tumors.

Preusser M, Bienkowski M, Birner P.

Expert Opin Investig Drugs. 2016;25(1):7-14. doi: 10.1517/13543784.2016.1110143. Epub 2015 Nov 4. Review.

PMID:
26536389
31.

Clinical impact of c-MET expression and mutational status in patients with colorectal cancer lung metastases.

Schweiger T, Starkl V, Glueck O, Glogner C, Traxler D, Jedamzik J, Liebmann-Reindl S, Birner P, Streubel B, Klepetko W, Hoetzenecker K.

Eur J Cardiothorac Surg. 2016 Apr;49(4):1103-11; discussion 1111. doi: 10.1093/ejcts/ezv323. Epub 2015 Oct 24.

PMID:
26503729
32.

Increased lymphangiogenesis in lung metastases from colorectal cancer is associated with early lymph node recurrence and decreased overall survival.

Schweiger T, Nikolowsky C, Graeter T, Seebacher G, Laufer J, Glueck O, Glogner C, Birner P, Lang G, Klepetko W, Ankersmit HJ, Hoetzenecker K.

Clin Exp Metastasis. 2016 Feb;33(2):133-41. doi: 10.1007/s10585-015-9763-9. Epub 2015 Oct 23.

PMID:
26498830
33.

Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis.

Proestling K, Birner P, Gamperl S, Nirtl N, Marton E, Yerlikaya G, Wenzl R, Streubel B, Husslein H.

Reprod Biol Endocrinol. 2015 Jul 22;13:75. doi: 10.1186/s12958-015-0063-7.

34.

Spectrum of gene mutations detected by next generation exome sequencing in brain metastases of lung adenocarcinoma.

Preusser M, Berghoff AS, Koller R, Zielinski CC, Hainfellner JA, Liebmann-Reindl S, Popitsch N, Geier CB, Streubel B, Birner P.

Eur J Cancer. 2015 Sep;51(13):1803-11. doi: 10.1016/j.ejca.2015.06.107. Epub 2015 Jul 8.

PMID:
26164066
35.

The chemokine receptor CXCR7 influences prognosis in human glioma in an IDH1-dependent manner.

Birner P, Tchorbanov A, Natchev S, Tuettenberg J, Guentchev M.

J Clin Pathol. 2015 Oct;68(10):830-4. doi: 10.1136/jclinpath-2015-202886. Epub 2015 Jun 24.

PMID:
26109200
36.

Erratum. Plasma fibrinogen and blood platelet counts are associated with response to neoadjuvant therapy in esophageal cancer.

Ilhan-Mutlu A, Starlinger P, Perkmann T, Schoppmann SF, Preusser M, Birner P.

Biomark Med. 2015;9(6):617. doi: 10.2217/bmm.15.24. No abstract available.

37.

microRNA-21 expression is elevated in esophageal adenocarcinoma after neoadjuvant chemotherapy.

Ilhan-Mutlu A, Tezcan G, Schoppmann SF, Preusser M, Spyridoula K, Karanikas G, Birner P.

Cancer Invest. 2015 Jul;33(6):246-50. doi: 10.3109/07357907.2015.1024319. Epub 2015 May 7.

PMID:
25950983
38.

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.

Shalapour S, Font-Burgada J, Di Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, Willimsky G, Ammirante M, Strasner A, Hansel DE, Jamieson C, Kane CJ, Klatte T, Birner P, Kenner L, Karin M.

Nature. 2015 May 7;521(7550):94-8. doi: 10.1038/nature14395. Epub 2015 Apr 29.

39.

Evaluation of tyrosine kinase receptors in brain metastases of clear cell renal cell carcinoma reveals cMet as a negative prognostic factor.

Schiefer AI, Mesteri I, Berghoff AS, Haitel A, Schmidinger M, Preusser M, Birner P.

Histopathology. 2015 Dec;67(6):799-805. doi: 10.1111/his.12709. Epub 2015 Jun 7.

PMID:
25847631
40.

Plasma fibrinogen and blood platelet counts are associated with response to neoadjuvant therapy in esophageal cancer.

Ilhan-Mutlu A, Starlinger P, Perkmann T, Schoppmann SF, Preusser M, Birner P.

Biomark Med. 2015;9(4):327-35. doi: 10.2217/bmm.14.111. Erratum in: Biomark Med. 2015;9(6):617.

PMID:
25808437
41.

Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases.

Schweiger T, Nikolowsky C, Starlinger P, Traxler D, Zimmermann M, Birner P, Hegedüs B, Dome B, Bergmann M, Mildner M, Klepetko W, Hoetzenecker K, Ankersmit HJ.

PLoS One. 2015 Mar 20;10(3):e0120724. doi: 10.1371/journal.pone.0120724. eCollection 2015.

42.

JunB and PTEN in prostate cancer: 'loss is nothing else than change'.

Birner P, Egger G, Merkel O, Kenner L.

Cell Death Differ. 2015 Apr;22(4):522-3. doi: 10.1038/cdd.2014.232. No abstract available.

43.

Tumour-infiltrating lymphocytes and expression of programmed death ligand 1 (PD-L1) in melanoma brain metastases.

Berghoff AS, Ricken G, Widhalm G, Rajky O, Dieckmann K, Birner P, Bartsch R, Höller C, Preusser M.

Histopathology. 2015 Jan;66(2):289-99. doi: 10.1111/his.12537. Epub 2014 Nov 10.

PMID:
25314639
44.

Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues.

Berghoff AS, Bartsch R, Wöhrer A, Streubel B, Birner P, Kros JM, Brastianos PK, von Deimling A, Preusser M.

Acta Neuropathol. 2014 Dec;128(6):879-91. doi: 10.1007/s00401-014-1350-7. Epub 2014 Oct 7. Review.

PMID:
25287912
45.

Differential role of angiogenesis and tumour cell proliferation in brain metastases according to primary tumour type: analysis of 639 cases.

Berghoff AS, Ilhan-Mutlu A, Dinhof C, Magerle M, Hackl M, Widhalm G, Hainfellner JA, Dieckmann K, Pichler J, Hutterer M, Melchardt T, Bartsch R, Zielinski CC, Birner P, Preusser M.

Neuropathol Appl Neurobiol. 2015 Feb;41(2):e41-55. doi: 10.1111/nan.12185.

PMID:
25256708
46.

Local and systemic RAGE axis changes in pulmonary hypertension: CTEPH and iPAH.

Moser B, Megerle A, Bekos C, Janik S, Szerafin T, Birner P, Schiefer AI, Mildner M, Lang I, Skoro-Sajer N, Sadushi-Kolici R, Taghavi S, Klepetko W, Ankersmit HJ.

PLoS One. 2014 Sep 4;9(9):e106440. doi: 10.1371/journal.pone.0106440. eCollection 2014.

47.

αvβ3, αvβ5 and αvβ6 integrins in brain metastases of lung cancer.

Berghoff AS, Kovanda AK, Melchardt T, Bartsch R, Hainfellner JA, Sipos B, Schittenhelm J, Zielinski CC, Widhalm G, Dieckmann K, Weller M, Goodman SL, Birner P, Preusser M.

Clin Exp Metastasis. 2014 Oct;31(7):841-51. doi: 10.1007/s10585-014-9675-0. Epub 2014 Aug 24.

PMID:
25150423
48.

MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases.

Birner P, Berghoff AS, Dinhof C, Pirker C, Capper D, Schoppmann SF, Petzelbauer P, von Deimling A, Berger W, Preusser M.

Arch Dermatol Res. 2014 Dec;306(10):873-84. doi: 10.1007/s00403-014-1490-6. Epub 2014 Jul 30.

PMID:
25073704
49.

Amplification and overexpression of CMET is a common event in brain metastases of non-small cell lung cancer.

Preusser M, Streubel B, Berghoff AS, Hainfellner JA, von Deimling A, Widhalm G, Dieckmann K, Wöhrer A, Hackl M, Zielinski C, Birner P.

Histopathology. 2014 Nov;65(5):684-92. doi: 10.1111/his.12475. Epub 2014 Aug 5.

PMID:
25039982
50.

Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients.

Berghoff AS, Bartsch R, Preusser M, Ricken G, Steger GG, Bago-Horvath Z, Rudas M, Streubel B, Dubsky P, Gnant M, Fitzal F, Zielinski CC, Birner P.

Breast. 2014 Oct;23(5):637-43. doi: 10.1016/j.breast.2014.06.011. Epub 2014 Jul 10.

PMID:
25017122

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