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Impact of QRS Duration and Ventricular Pacing on Clinical and Arrhythmic Outcomes in Continuous Flow Left Ventricular Assist Device Recipients: A Multicenter Study.

Gopinathannair R, Roukoz H, Trivedi JR, Cowger J, Bhan A, Ravichandran A, Bhat G, Birks EJ, Slaughter MS, Ahmed MM.

J Card Fail. 2019 May;25(5):355-363. doi: 10.1016/j.cardfail.2019.02.013. Epub 2019 Feb 21.


Management of Antiplatelet Therapy During Continuous-Flow Left Ventricular Assist Device Support After Thrombotic Hemorrhagic Events.

Gallo M, Trivedi JR, Mondal NK, Birks EJ, Slaughter M.

ASAIO J. 2018 Dec 18. doi: 10.1097/MAT.0000000000000935. [Epub ahead of print]


Left ventricular assist device explantation after myocardial recovery.

Gallo M, Trivedi JR, Monreal G, Birks EJ, Slaughter MS.

Multimed Man Cardiothorac Surg. 2018 Jan 29;2018. doi: 10.1510/mmcts.2018.006.


HVAD: The ENDURANCE Supplemental Trial.

Milano CA, Rogers JG, Tatooles AJ, Bhat G, Slaughter MS, Birks EJ, Mokadam NA, Mahr C, Miller JS, Markham DW, Jeevanandam V, Uriel N, Aaronson KD, Vassiliades TA, Pagani FD; ENDURANCE Investigators.

JACC Heart Fail. 2018 Sep;6(9):792-802. doi: 10.1016/j.jchf.2018.05.012. Epub 2018 Jul 11.


Cardiac Resynchronization Therapy and Clinical Outcomes in Continuous Flow Left Ventricular Assist Device Recipients.

Gopinathannair R, Roukoz H, Bhan A, Ravichandran A, Ahmed MM, Familtsev D, Bhat G, Cowger J, Abdullah M, Sandesara C, Dhawan R, Birks EJ, Trivedi JR, Slaughter MS.

J Am Heart Assoc. 2018 Jun 15;7(12). pii: e009091. doi: 10.1161/JAHA.118.009091.


Stopping LVAD Bleeding: A Piece of the Puzzle.

Birks EJ.

Circ Res. 2017 Sep 29;121(8):902-904. doi: 10.1161/CIRCRESAHA.117.311759. No abstract available.


Reply: Left Ventricle Assist Device Recovery Should Include Recovery of Ventilatory and Autonomic Nervous System Abnormalities.

Jakovljevic DG, MacGowan GA, Birks EJ.

J Am Coll Cardiol. 2017 Sep 19;70(12):1538-1539. doi: 10.1016/j.jacc.2017.06.070. No abstract available.


Intrapericardial Left Ventricular Assist Device for Advanced Heart Failure.

Rogers JG, Pagani FD, Tatooles AJ, Bhat G, Slaughter MS, Birks EJ, Boyce SW, Najjar SS, Jeevanandam V, Anderson AS, Gregoric ID, Mallidi H, Leadley K, Aaronson KD, Frazier OH, Milano CA.

N Engl J Med. 2017 Feb 2;376(5):451-460. doi: 10.1056/NEJMoa1602954.


Metabolic Reprogramming After Left Ventricular Assist Device: Remodeling Without Recovery of Cardiac Energetics.

Rame JE, Birks EJ.

JACC Basic Transl Sci. 2016 Oct 31;1(6):445-448. doi: 10.1016/j.jacbts.2016.09.003. eCollection 2016 Oct. No abstract available.


Differences in Status 1A Heart Transplantation Survival in the Continuous Flow Left Ventricular Assist Device Era.

Trivedi JR, Rajagopal K, Schumer EM, Birks EJ, Lenneman A, Cheng A, Slaughter MS.

Ann Thorac Surg. 2016 Nov;102(5):1512-1516. doi: 10.1016/j.athoracsur.2016.04.027. Epub 2016 Jun 18.


Another Grain in the Search for the True Rate of Myocardial Recovery.

Birks EJ.

J Am Coll Cardiol. 2016 Oct 4;68(14):1554-6. doi: 10.1016/j.jacc.2016.07.742. No abstract available.


Recovery of Cardiac Function in Cardiomyopathy Caused by Titin Truncation.

Felkin LE, Walsh R, Ware JS, Yacoub MH, Birks EJ, Barton PJ, Cook SA.

JAMA Cardiol. 2016 May 1;1(2):234-5. doi: 10.1001/jamacardio.2016.0208. No abstract available.


The Promise of Recovery.

Birks EJ.

JACC Heart Fail. 2016 Jul;4(7):577-579. doi: 10.1016/j.jchf.2016.04.003. Epub 2016 Jun 8. No abstract available.


Donor Oversizing Results in Improved Survival in Patients with Left Ventricular Assist Device.

Schumer EM, Black MC, Rogers MP, Trivedi JR, Birks EJ, Lenneman AJ, Cheng A, Slaughter MS.

ASAIO J. 2016 Sep-Oct;62(5):571-7. doi: 10.1097/MAT.0000000000000399.


Safety and Feasibility of Induction Immunosuppression When Driveline Infection Is an Indication for Cardiac Transplantation.

Bhatia N, Voelkel AJ, Hussain Z, Sharma UC, Slaughter MS, Birks EJ, McCants KC.

Thorac Cardiovasc Surg. 2015 Dec;63(8):675-83. doi: 10.1055/s-0035-1564449. Epub 2015 Sep 14.


Echocardiography in the Management of Patients with Left Ventricular Assist Devices: Recommendations from the American Society of Echocardiography.

Stainback RF, Estep JD, Agler DA, Birks EJ, Bremer M, Hung J, Kirkpatrick JN, Rogers JG, Shah NR; American Society of Echocardiography.

J Am Soc Echocardiogr. 2015 Aug;28(8):853-909. doi: 10.1016/j.echo.2015.05.008. No abstract available.


An examination of survival by sex and race in the HeartWare Ventricular Assist Device for the Treatment of Advanced Heart Failure (ADVANCE) Bridge to Transplant (BTT) and continued access protocol trials.

Birks EJ, McGee EC Jr, Aaronson KD, Boyce S, Cotts WG, Najjar SS, Pagani FD, Hathaway DR, Najarian K, Jacoski MV, Slaughter MS; ADVANCE Trial Investigators.

J Heart Lung Transplant. 2015 Jun;34(6):815-24. doi: 10.1016/j.healun.2014.12.011. Epub 2014 Dec 29.


Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.

Roberts AM, Ware JS, Herman DS, Schafer S, Baksi J, Bick AG, Buchan RJ, Walsh R, John S, Wilkinson S, Mazzarotto F, Felkin LE, Gong S, MacArthur JA, Cunningham F, Flannick J, Gabriel SB, Altshuler DM, Macdonald PS, Heinig M, Keogh AM, Hayward CS, Banner NR, Pennell DJ, O'Regan DP, San TR, de Marvao A, Dawes TJ, Gulati A, Birks EJ, Yacoub MH, Radke M, Gotthardt M, Wilson JG, O'Donnell CJ, Prasad SK, Barton PJ, Fatkin D, Hubner N, Seidman JG, Seidman CE, Cook SA.

Sci Transl Med. 2015 Jan 14;7(270):270ra6. doi: 10.1126/scitranslmed.3010134.


Impact of cardiac resynchronization therapy on clinical outcomes in patients with continuous-flow left ventricular assist devices.

Gopinathannair R, Birks EJ, Trivedi JR, McCants KC, Sutton BS, Deam AG, Slaughter MS, Hottigoudar RU.

J Card Fail. 2015 Mar;21(3):226-32. doi: 10.1016/j.cardfail.2014.12.006. Epub 2014 Dec 17.


Hematologic markers better predict left ventricular assist device thrombosis than echocardiographic or pump parameters.

Bartoli CR, Ghotra AS, Pachika AR, Birks EJ, McCants KC.

Thorac Cardiovasc Surg. 2014 Aug;62(5):414-8. doi: 10.1055/s-0034-1376891. Epub 2014 Jul 4.


The association of pretransplant HeartMate II left ventricular assist device placement and heart transplantation mortality.

Donneyong M, Cheng A, Trivedi JR, Schumer E, McCants KC, Birks EJ, Slaughter MS.

ASAIO J. 2014 May-Jun;60(3):294-9. doi: 10.1097/MAT.0000000000000065.


Results of the destination therapy post-food and drug administration approval study with a continuous flow left ventricular assist device: a prospective study using the INTERMACS registry (Interagency Registry for Mechanically Assisted Circulatory Support).

Jorde UP, Kushwaha SS, Tatooles AJ, Naka Y, Bhat G, Long JW, Horstmanshof DA, Kormos RL, Teuteberg JJ, Slaughter MS, Birks EJ, Farrar DJ, Park SJ; HeartMate II Clinical Investigators.

J Am Coll Cardiol. 2014 May 6;63(17):1751-7. doi: 10.1016/j.jacc.2014.01.053. Epub 2014 Mar 5.


Treatment strategies for myocardial recovery in heart failure.

Lenneman AJ, Birks EJ.

Curr Treat Options Cardiovasc Med. 2014 Mar;16(3):287. doi: 10.1007/s11936-013-0287-9.


Molecular changes after left ventricular assist device support for heart failure.

Birks EJ.

Circ Res. 2013 Aug 30;113(6):777-91. doi: 10.1161/CIRCRESAHA.113.301413. Review.


Catheter ablation of atrial flutter in patients with left ventricular assist device improves symptoms of right heart failure.

Hottigoudar RU, Deam AG, Birks EJ, McCants KC, Slaughter MS, Gopinathannair R.

Congest Heart Fail. 2013 Jul-Aug;19(4):165-71. doi: 10.1111/chf.12034.


Cardiovascular autonomic control in patients undergoing left ventricular assist device (LVAD) support and pharmacologic therapy.

Nunan D, Sandercock GR, George RS, Jakovljevic DG, Donovan G, Bougard R, Yacoub MH, Brodie DA, Birks EJ.

Int J Cardiol. 2013 Oct 9;168(4):4145-9. doi: 10.1016/j.ijcard.2013.07.075. Epub 2013 Jul 26.


Vascular endothelial growth factor in heart failure.

Taimeh Z, Loughran J, Birks EJ, Bolli R.

Nat Rev Cardiol. 2013 Sep;10(9):519-30. doi: 10.1038/nrcardio.2013.94. Epub 2013 Jul 16. Review.


HeartWare ventricular assist system for bridge to transplant: combined results of the bridge to transplant and continued access protocol trial.

Slaughter MS, Pagani FD, McGee EC, Birks EJ, Cotts WG, Gregoric I, Howard Frazier O, Icenogle T, Najjar SS, Boyce SW, Acker MA, John R, Hathaway DR, Najarian KB, Aaronson KD; HeartWare Bridge to Transplant ADVANCE Trial Investigators.

J Heart Lung Transplant. 2013 Jul;32(7):675-83. doi: 10.1016/j.healun.2013.04.004.


The effect of long-term left ventricular assist device support on myocardial sympathetic activity in patients with non-ischaemic dilated cardiomyopathy.

George RS, Birks EJ, Cheetham A, Webb C, Smolenski RT, Khaghani A, Yacoub MH, Kelion A.

Eur J Heart Fail. 2013 Sep;15(9):1035-43. doi: 10.1093/eurjhf/hft059. Epub 2013 Apr 21.


Percutaneous closure of a patent foramen ovale to prevent paradoxical thromboembolism in a patient with a continuous-flow LVAD.

Bartoli CR, McCants KC, Birks EJ, Flaherty MP, Slaughter MS.

J Invasive Cardiol. 2013 Mar;25(3):154-6.


Long-term outcomes of patients bridged to recovery versus patients bridged to transplantation.

Birks EJ, George RS, Firouzi A, Wright G, Bahrami T, Yacoub MH, Khaghani A.

J Thorac Cardiovasc Surg. 2012 Jul;144(1):190-6. doi: 10.1016/j.jtcvs.2012.03.021. Epub 2012 Apr 11.


A changing trend toward destination therapy: are we treating the same patients differently?

Birks EJ.

Tex Heart Inst J. 2011;38(5):552-4. No abstract available.


Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart.

Knöll R, Linke WA, Zou P, Miocic S, Kostin S, Buyandelger B, Ku CH, Neef S, Bug M, Schäfer K, Knöll G, Felkin LE, Wessels J, Toischer K, Hagn F, Kessler H, Didié M, Quentin T, Maier LS, Teucher N, Unsöld B, Schmidt A, Birks EJ, Gunkel S, Lang P, Granzier H, Zimmermann WH, Field LJ, Faulkner G, Dobbelstein M, Barton PJ, Sattler M, Wilmanns M, Chien KR.

Circ Res. 2011 Sep 16;109(7):758-69. doi: 10.1161/CIRCRESAHA.111.245787. Epub 2011 Jul 28.


Relationship between peak cardiac pumping capability and selected exercise-derived prognostic indicators in patients treated with left ventricular assist devices.

Jakovljevic DG, Birks EJ, George RS, Trenell MI, Seferovic PM, Yacoub MH, Brodie DA.

Eur J Heart Fail. 2011 Sep;13(9):992-9. doi: 10.1093/eurjhf/hfr069. Epub 2011 Jun 30.


Heart transplant vs left ventricular assist device in heart transplant-eligible patients.

Williams ML, Trivedi JR, McCants KC, Prabhu SD, Birks EJ, Oliver L, Slaughter MS.

Ann Thorac Surg. 2011 May;91(5):1330-3; discussion 1333-4. doi: 10.1016/j.athoracsur.2011.01.062. Epub 2011 Mar 24.


Destination therapy with left ventricular assist devices: patient selection and outcomes.

Slaughter MS, Meyer AL, Birks EJ.

Curr Opin Cardiol. 2011 May;26(3):232-6. doi: 10.1097/HCO.0b013e328345aff4. Review.


Reverse remodelling and recovery from heart failure are associated with complex patterns of gene expression.

Felkin LE, Lara-Pezzi EA, Hall JL, Birks EJ, Barton PJ.

J Cardiovasc Transl Res. 2011 Jun;4(3):321-31. doi: 10.1007/s12265-011-9267-1. Epub 2011 Mar 22.


Clinical, molecular, and genomic changes in response to a left ventricular assist device.

Hall JL, Fermin DR, Birks EJ, Barton PJ, Slaughter M, Eckman P, Baba HA, Wohlschlaeger J, Miller LW.

J Am Coll Cardiol. 2011 Feb 8;57(6):641-52. doi: 10.1016/j.jacc.2010.11.010. Review.


Reversal of severe heart failure with a continuous-flow left ventricular assist device and pharmacological therapy: a prospective study.

Birks EJ, George RS, Hedger M, Bahrami T, Wilton P, Bowles CT, Webb C, Bougard R, Amrani M, Yacoub MH, Dreyfus G, Khaghani A.

Circulation. 2011 Feb 1;123(4):381-90. doi: 10.1161/CIRCULATIONAHA.109.933960. Epub 2011 Jan 17.


Molecular changes occurring during reverse remodelling following left ventricular assist device support.

Birks EJ, George RS.

J Cardiovasc Transl Res. 2010 Dec;3(6):635-42. doi: 10.1007/s12265-010-9220-8. Epub 2010 Sep 4. Review.


Echocardiographic assessment of flow across continuous-flow ventricular assist devices at low speeds.

George RS, Sabharwal NK, Webb C, Yacoub MH, Bowles CT, Hedger M, Khaghani A, Birks EJ.

J Heart Lung Transplant. 2010 Nov;29(11):1245-52. doi: 10.1016/j.healun.2010.05.032. Epub 2010 Aug 5.


The impact of acute reduction of continuous-flow left ventricular assist device support on cardiac and exercise performance.

Jakovljevic DG, George RS, Nunan D, Donovan G, Bougard RS, Yacoub MH, Birks EJ, Brodie DA.

Heart. 2010 Sep;96(17):1390-5. doi: 10.1136/hrt.2010.193698. Epub 2010 Jul 18.


Chronic treatment with clenbuterol modulates endothelial progenitor cells and circulating factors in a murine model of cardiomyopathy.

Rider JE, Polster SP, Lee S, Charles NJ, Adhikari N, Mariash A, Tadros G, Stangland J, Smolenski RT, Terracciano CM, Barton PJ, Birks EJ, Yacoub MH, Miller LW, Hall JL.

J Cardiovasc Transl Res. 2009 Jun;2(2):182-90. doi: 10.1007/s12265-009-9089-6. Epub 2009 Mar 27.


Myocardial recovery in patients with chronic heart failure: is it real?

Birks EJ.

J Card Surg. 2010 Jul;25(4):472-7. doi: 10.1111/j.1540-8191.2010.01051.x. Epub 2010 Jun 7. Review.


Comparison of cardiac power output and exercise performance in patients with left ventricular assist devices, explanted (recovered) patients, and those with moderate to severe heart failure.

Jakovljevic DG, George RS, Donovan G, Nunan D, Henderson K, Bougard RS, Yacoub MH, Birks EJ, Brodie DA.

Am J Cardiol. 2010 Jun 15;105(12):1780-5. doi: 10.1016/j.amjcard.2010.01.362. Epub 2010 Apr 27.


Sustained myocardial recovery 5 years after in situ disconnection of a Jarvik 2000 device.

George RS, Khaghani C, Bowles CT, Khaghani A, Birks EJ.

J Heart Lung Transplant. 2010 May;29(5):587-8. doi: 10.1016/j.healun.2009.12.002. Epub 2010 Mar 6. No abstract available.


Left ventricular assist devices.

Birks EJ.

Heart. 2010 Jan;96(1):63-71. doi: 10.1136/hrt.2007.130740. Epub 2009 Jul 16.


Bridging patients after salvage from bridge to decision directly to transplant by means of prolonged support with the CentriMag short-term centrifugal pump.

Haj-Yahia S, Birks EJ, Amrani M, Petrou M, Bahrami T, Dreyfus G, Khaghani A.

J Thorac Cardiovasc Surg. 2009 Jul;138(1):227-30. doi: 10.1016/j.jtcvs.2009.03.018. Epub 2009 May 12.


Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice.

Breckenridge RA, Zuberi Z, Gomes J, Orford R, Dupays L, Felkin LE, Clark JE, Magee AI, Ehler E, Birks EJ, Barton PJ, Tinker A, Mohun TJ.

J Mol Cell Cardiol. 2009 Jul;47(1):133-41. doi: 10.1016/j.yjmcc.2009.04.007. Epub 2009 Apr 17.


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