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Items: 6


Cenerimod, a novel selective S1P1 receptor modulator with unique signaling properties.

Piali L, Birker-Robaczewska M, Lescop C, Froidevaux S, Schmitz N, Morrison K, Kohl C, Rey M, Studer R, Vezzali E, Hess P, Clozel M, Steiner B, Bolli MH, Nayler O.

Pharmacol Res Perspect. 2017 Dec;5(6). doi: 10.1002/prp2.370.


S1P1 Modulator-Induced G αi Signaling and β-Arrestin Recruitment Are Both Necessary to Induce Rapid and Efficient Reduction of Blood Lymphocyte Count In Vivo.

Birker-Robaczewska M, Bolli M, Rey M, de Kanter R, Kohl C, Lescop C, Boucher M, Poirey S, Steiner B, Nayler O.

Mol Pharmacol. 2018 Feb;93(2):109-118. doi: 10.1124/mol.117.109140. Epub 2017 Dec 4.


A novel genomic signature with translational significance for human idiopathic pulmonary fibrosis.

Bauer Y, Tedrow J, de Bernard S, Birker-Robaczewska M, Gibson KF, Guardela BJ, Hess P, Klenk A, Lindell KO, Poirey S, Renault B, Rey M, Weber E, Nayler O, Kaminski N.

Am J Respir Cell Mol Biol. 2015 Feb;52(2):217-31. doi: 10.1165/rcmb.2013-0310OC.


bFGF induces S1P1 receptor expression and functionality in human pulmonary artery smooth muscle cells.

Birker-Robaczewska M, Studer R, Haenig B, Menyhart K, Hofmann S, Nayler O.

J Cell Biochem. 2008 Nov 1;105(4):1139-45. doi: 10.1002/jcb.21918.


Pharmacology of the urotensin-II receptor antagonist palosuran (ACT-058362; 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulfate salt): first demonstration of a pathophysiological role of the urotensin System.

Clozel M, Binkert C, Birker-Robaczewska M, Boukhadra C, Ding SS, Fischli W, Hess P, Mathys B, Morrison K, Müller C, Müller C, Nayler O, Qiu C, Rey M, Scherz MW, Velker J, Weller T, Xi JF, Ziltener P.

J Pharmacol Exp Ther. 2004 Oct;311(1):204-12. Epub 2004 May 14.


The expression of urotensin II receptor (U2R) is up-regulated by interferon-gamma.

Birker-Robaczewska M, Boukhadra C, Studer R, Mueller C, Binkert C, Nayler O.

J Recept Signal Transduct Res. 2003;23(4):289-305.


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