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Items: 1 to 50 of 118

1.

Publisher Correction: New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery.

Angelini G, Castagneto Gissey L, Corpo GD, Giordano C, Cerbelli B, Severino A, Manco M, Basso N, Birkenfeld AL, Bornstein SR, Genco A, Mingrone G, Casella G.

Sci Rep. 2020 Feb 12;10(1):2786. doi: 10.1038/s41598-020-58961-0.

2.

Solute Carrier Transporters as Potential Targets for the Treatment of Metabolic Disease.

Schumann T, König J, Henke C, Willmes DM, Bornstein SR, Jordan J, Fromm MF, Birkenfeld AL.

Pharmacol Rev. 2020 Jan;72(1):343-379. doi: 10.1124/pr.118.015735. Review.

PMID:
31882442
3.

Position Paper on Lipid Therapy in Patients with Diabetes Mellitus.

Parhofer KG, Birkenfeld AL, Krone W, Lehrke M, Marx N, Merkel M, Schütt KS, Zirlik A, Müller-Wieland D.

Exp Clin Endocrinol Diabetes. 2019 Dec;127(S 01):S97-S101. doi: 10.1055/a-1018-9228. Epub 2019 Dec 20. No abstract available.

PMID:
31860929
4.

Therapy of Type 2 Diabetes.

Landgraf R, Aberle J, Birkenfeld AL, Gallwitz B, Kellerer M, Klein H, Müller-Wieland D, Nauck MA, Reuter HM, Siegel E.

Exp Clin Endocrinol Diabetes. 2019 Dec;127(S 01):S73-S92. doi: 10.1055/a-1018-9106. Epub 2019 Dec 20. No abstract available.

PMID:
31860927
5.

Cardiovascular risk factors in patients with premature cardiovascular events attending the University of Dresden Lipid Clinic.

Schatz U, Fischer S, Müller G, Tselmin S, Birkenfeld AL, Julius U, März W, Bornstein SR.

Atheroscler Suppl. 2019 Dec;40:94-99. doi: 10.1016/j.atherosclerosissup.2019.08.044.

PMID:
31818455
6.

Actual situation of lipoprotein apheresis in patients with elevated lipoprotein(a) levels.

Julius U, Tselmin S, Schatz U, Fischer S, Birkenfeld AL, Bornstein SR.

Atheroscler Suppl. 2019 Dec;40:1-7. doi: 10.1016/j.atherosclerosissup.2019.08.043.

PMID:
31818437
7.

New insight into the mechanisms of ectopic fat deposition improvement after bariatric surgery.

Angelini G, Castagneto Gissey L, Del Corpo G, Giordano C, Cerbelli B, Severino A, Manco M, Basso N, Birkenfeld AL, Bornstein SR, Genco A, Mingrone G, Casella G.

Sci Rep. 2019 Nov 21;9(1):17315. doi: 10.1038/s41598-019-53702-4. Erratum in: Sci Rep. 2020 Feb 12;10(1):2786.

8.

Obesity Does Not Modulate the Glycometabolic Benefit of Insoluble Cereal Fibre in Subjects with Prediabetes-A Stratified Post Hoc Analysis of the Optimal Fibre Trial (OptiFiT).

Kabisch S, Meyer NMT, Honsek C, Gerbracht C, Dambeck U, Kemper M, Osterhoff MA, Birkenfeld AL, Arafat AM, Weickert MO, Pfeiffer AFH.

Nutrients. 2019 Nov 11;11(11). pii: E2726. doi: 10.3390/nu11112726.

9.

Fasting Glucose State Determines Metabolic Response to Supplementation with Insoluble Cereal Fibre: A Secondary Analysis of the Optimal Fibre Trial (OptiFiT).

Kabisch S, Meyer NMT, Honsek C, Gerbracht C, Dambeck U, Kemper M, Osterhoff MA, Birkenfeld AL, Arafat AM, Hjorth MF, Weickert MO, Pfeiffer AFH.

Nutrients. 2019 Oct 6;11(10). pii: E2385. doi: 10.3390/nu11102385.

10.

Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial.

Kahl S, Gancheva S, Straßburger K, Herder C, Machann J, Katsuyama H, Kabisch S, Henkel E, Kopf S, Lagerpusch M, Kantartzis K, Kupriyanova Y, Markgraf D, van Gemert T, Knebel B, Wolkersdorfer MF, Kuss O, Hwang JH, Bornstein SR, Kasperk C, Stefan N, Pfeiffer A, Birkenfeld AL, Roden M.

Diabetes Care. 2020 Feb;43(2):298-305. doi: 10.2337/dc19-0641. Epub 2019 Sep 20.

PMID:
31540903
11.

Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells.

Binger KJ, Neukam M, Tattikota SG, Qadri F, Puchkov D, Willmes DM, Wurmsee S, Geisberger S, Dechend R, Raile K, Kurth T, Nguyen G, Poy MN, Solimena M, Muller DN, Birkenfeld AL.

Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19983-19988. doi: 10.1073/pnas.1903678116. Epub 2019 Sep 16.

PMID:
31527264
12.

Are Lifestyle Therapies Effective for NAFLD Treatment?

El-Agroudy NN, Kurzbach A, Rodionov RN, O'Sullivan J, Roden M, Birkenfeld AL, Pesta DH.

Trends Endocrinol Metab. 2019 Oct;30(10):701-709. doi: 10.1016/j.tem.2019.07.013. Epub 2019 Aug 15. Review.

13.

Correction: Lipid Profiles in Lyme Borreliosis: A Potential Role for Apheresis?

Straube R, Voit-Bak K, Gor A, Steinmeier T, Chrousos GP, Boehm BO, Birkenfeld AL, Barbir M, Balanzew W, Bornstein SR.

Horm Metab Res. 2019 Aug;51(8):554. doi: 10.1055/a-0976-7010. Epub 2019 Aug 13. No abstract available.

PMID:
31408899
14.

Improved treatment satisfaction in patients with type 2 diabetes treated with once-weekly semaglutide in the SUSTAIN trials.

Jendle J, Birkenfeld AL, Polonsky WH, Silver R, Uusinarkaus K, Hansen T, Håkan-Bloch J, Tadayon S, Davies MJ.

Diabetes Obes Metab. 2019 Oct;21(10):2315-2326. doi: 10.1111/dom.13816. Epub 2019 Jul 12.

15.

Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.

Husain M, Birkenfeld AL, Donsmark M, Dungan K, Eliaschewitz FG, Franco DR, Jeppesen OK, Lingvay I, Mosenzon O, Pedersen SD, Tack CJ, Thomsen M, Vilsbøll T, Warren ML, Bain SC; PIONEER 6 Investigators.

N Engl J Med. 2019 Aug 29;381(9):841-851. doi: 10.1056/NEJMoa1901118. Epub 2019 Jun 11.

PMID:
31185157
16.

Lipid Profiles in Lyme Borreliosis: A Potential Role for Apheresis?

Straube R, Voit-Bak K, Gor A, Steinmeier T, Chrousos GP, Boehm BO, Birkenfeld AL, Barbir M, Balanzew W, Bornstein SR.

Horm Metab Res. 2019 May;51(5):326-329. doi: 10.1055/a-0885-7169. Epub 2019 May 9. Erratum in: Horm Metab Res. 2019 Aug;51(8):554.

PMID:
31071737
17.

Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial.

Rosenstock J, Allison D, Birkenfeld AL, Blicher TM, Deenadayalan S, Jacobsen JB, Serusclat P, Violante R, Watada H, Davies M; PIONEER 3 Investigators.

JAMA. 2019 Apr 16;321(15):1466-1480. doi: 10.1001/jama.2019.2942.

18.

Corrigendum to "Intensive lifestyle modifications with or without liraglutide 3mg vs. sleeve gastrectomy: A three-arm non-randomised, controlled, pilot study" [Diabetes Metab. 44 (2018) 235-242].

Capristo E, Panunzi S, De Gaetano A, Raffaelli M, Guidone C, Iaconelli A, L'Abbate L, Birkenfeld AL, Bellantone R, Bornstein S, Mingrone G.

Diabetes Metab. 2019 Mar 9. pii: S1262-3636(19)30031-X. doi: 10.1016/j.diabet.2019.02.004. [Epub ahead of print] No abstract available.

PMID:
30857948
19.

Beta-Aminoisobutyric Acid as a Novel Regulator of Carbohydrate and Lipid Metabolism.

Tanianskii DA, Jarzebska N, Birkenfeld AL, O'Sullivan JF, Rodionov RN.

Nutrients. 2019 Feb 28;11(3). pii: E524. doi: 10.3390/nu11030524. Review.

20.

Correction to: Intravenous Ferric Carboxymaltose in Patients with Type 2 Diabetes Mellitus and Iron Deficiency: CLEVER Trial Study Design and Protocol.

Schindler C, Birkenfeld AL, Hanefeld M, Schatz U, Köhler C, Grüneberg M, Tschöpe D, Blüher M, Hasslacher C, Bornstein SR.

Diabetes Ther. 2019 Feb;10(1):329-331. doi: 10.1007/s13300-018-0546-6.

21.

Response to Letter to the Editor: "Incidence of Hypoglycemia After Gastric Bypass vs Sleeve Gastrectomy: A Randomized Trial".

Capristo E, Panunzi S, De Gaetano A, Spuntarelli V, Bellantone R, Giustacchini P, Birkenfeld AL, Amiel S, Bornstein SR, Raffaelli M, Mingrone G.

J Clin Endocrinol Metab. 2019 Mar 1;104(3):732-733. doi: 10.1210/jc.2018-01813. No abstract available.

PMID:
30285256
22.

Myocardial metabolism in heart failure: Purinergic signalling and other metabolic concepts.

Birkenfeld AL, Jordan J, Dworak M, Merkel T, Burnstock G.

Pharmacol Ther. 2019 Feb;194:132-144. doi: 10.1016/j.pharmthera.2018.08.015. Epub 2018 Aug 25. Review.

PMID:
30149104
23.

Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial.

O'Neil PM, Birkenfeld AL, McGowan B, Mosenzon O, Pedersen SD, Wharton S, Carson CG, Jepsen CH, Kabisch M, Wilding JPH.

Lancet. 2018 Aug 25;392(10148):637-649. doi: 10.1016/S0140-6736(18)31773-2. Epub 2018 Aug 16.

PMID:
30122305
24.

Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism.

Selch S, Chafai A, Sticht H, Birkenfeld AL, Fromm MF, König J.

Sci Rep. 2018 Jul 27;8(1):11330. doi: 10.1038/s41598-018-29547-8.

25.

β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice.

Tauscher S, Nakagawa H, Völker K, Werner F, Krebes L, Potapenko T, Doose S, Birkenfeld AL, Baba HA, Kuhn M.

Cardiovasc Diabetol. 2018 Jul 17;17(1):103. doi: 10.1186/s12933-018-0747-3.

26.

Natriuretic Peptides in Cardiovascular and Metabolic Crosstalk: Implications for Hypertension Management.

Jordan J, Birkenfeld AL, Melander O, Moro C.

Hypertension. 2018 Aug;72(2):270-276. doi: 10.1161/HYPERTENSIONAHA.118.11081. Epub 2018 Jun 25. Review. No abstract available.

PMID:
29941512
27.

The anorexigenic peptide neurotensin relates to insulin sensitivity in obese patients after BPD or RYGB metabolic surgery.

von Loeffelholz C, Gissey LC, Schumann T, Henke C, Kurzbach A, Struck J, Bergmann A, Hanefeld M, Schatz U, Bornstein SR, Casella G, Mingrone G, Birkenfeld AL.

Int J Obes (Lond). 2018 Dec;42(12):2057-2061. doi: 10.1038/s41366-018-0084-3. Epub 2018 May 24.

PMID:
29795470
28.

Characteristics of high- and low-risk individuals in the PRIORITY study: urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes.

Tofte N, Lindhardt M, Adamova K, Beige J, Beulens JWJ, Birkenfeld AL, Currie G, Delles C, Dimos I, Francová L, Frimodt-Møller M, Girman P, Göke R, Havrdova T, Kooy A, Mischak H, Navis G, Nijpels G, Noutsou M, Ortiz A, Parvanova A, Persson F, Ruggenenti PL, Rutters F, Rychlík I, Spasovski G, Speeckaert M, Trillini M, von der Leyen H, Rossing P.

Diabet Med. 2018 Oct;35(10):1375-1382. doi: 10.1111/dme.13669. Epub 2018 Jun 6.

PMID:
29781558
29.

Incidence of Hypoglycemia After Gastric Bypass vs Sleeve Gastrectomy: A Randomized Trial.

Capristo E, Panunzi S, De Gaetano A, Spuntarelli V, Bellantone R, Giustacchini P, Birkenfeld AL, Amiel S, Bornstein SR, Raffaelli M, Mingrone G.

J Clin Endocrinol Metab. 2018 Jun 1;103(6):2136-2146. doi: 10.1210/jc.2017-01695.

PMID:
29590421
30.

Fibre supplementation for the prevention of type 2 diabetes and improvement of glucose metabolism: the randomised controlled Optimal Fibre Trial (OptiFiT).

Honsek C, Kabisch S, Kemper M, Gerbracht C, Arafat AM, Birkenfeld AL, Dambeck U, Osterhoff MA, Weickert MO, Pfeiffer AFH.

Diabetologia. 2018 Jun;61(6):1295-1305. doi: 10.1007/s00125-018-4582-6. Epub 2018 Feb 28.

PMID:
29492637
31.

Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes.

Assefa B, Mahmoud AM, Pfeiffer AFH, Birkenfeld AL, Spranger J, Arafat AM.

Oxid Med Cell Longev. 2017;2017:3035184. doi: 10.1155/2017/3035184. Epub 2017 Dec 20.

32.

Intensive lifestyle modifications with or without liraglutide 3mg vs. sleeve gastrectomy: A three-arm non-randomised, controlled, pilot study.

Capristo E, Panunzi S, De Gaetano A, Raffaelli M, Guidone C, Iaconelli A, L'Abbate L, Birkenfeld AL, Bellantone R, Bornstein SR, Mingrone G.

Diabetes Metab. 2018 Jun;44(3):235-242. doi: 10.1016/j.diabet.2017.12.007. Epub 2017 Dec 29. Erratum in: Diabetes Metab. 2019 Mar 9;:.

PMID:
29398254
33.

Intravenous Ferric Carboxymaltose in Patients with Type 2 Diabetes Mellitus and Iron Deficiency: CLEVER Trial Study Design and Protocol.

Schindler C, Birkenfeld AL, Hanefeld M, Schatz U, Köhler C, Grüneberg M, Tschöpe D, Blüher M, Hasslacher C, Bornstein SR.

Diabetes Ther. 2018 Feb;9(1):37-47. doi: 10.1007/s13300-017-0330-z. Epub 2017 Nov 13. Erratum in: Diabetes Ther. 2018 Dec 6;:.

34.

Reply.

von Loeffelholz C, Birkenfeld AL.

Hepatology. 2018 Jan;67(1):452-453. doi: 10.1002/hep.29591. No abstract available.

PMID:
29024037
35.

Intra-individual variability and circadian rhythm of vascular endothelial growth factors in subjects with normal glucose tolerance and type 2 diabetes.

Hanefeld M, Engelmann K, Appelt D, Sandner D, Weigmann I, Ganz X, Pistrosch F, Köhler C, Gasparic A, Birkenfeld AL.

PLoS One. 2017 Oct 9;12(10):e0184234. doi: 10.1371/journal.pone.0184234. eCollection 2017.

36.

The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target.

Willmes DM, Kurzbach A, Henke C, Schumann T, Zahn G, Heifetz A, Jordan J, Helfand SL, Birkenfeld AL.

Pharmacol Ther. 2018 May;185:1-11. doi: 10.1016/j.pharmthera.2017.10.003. Epub 2017 Oct 5. Review.

37.

Glucagon Decreases IGF-1 Bioactivity in Humans, Independently of Insulin, by Modulating Its Binding Proteins.

Sarem Z, Bumke-Vogt C, Mahmoud AM, Assefa B, Weickert MO, Adamidou A, Bähr V, Frystyk J, Möhlig M, Spranger J, Lieske S, Birkenfeld AL, Pfeiffer AFH, Arafat AM.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3480-3490. doi: 10.1210/jc.2017-00558.

38.

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.

Heidenreich S, Witte N, Weber P, Goehring I, Tolkachov A, von Loeffelholz C, Döcke S, Bauer M, Stockmann M, Pfeiffer AFH, Birkenfeld AL, Pietzke M, Kempa S, Muenzner M, Schupp M.

Nat Commun. 2017 Aug 30;8(1):384. doi: 10.1038/s41467-017-00430-w.

39.

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschöp MH, Heinig M, Trajkovski M, Haucke V, Poy MN.

Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19.

40.

Urinary Lipidomics: evidence for multiple sources and sexual dimorphism in healthy individuals.

Graessler J, Mehnert CS, Schulte KM, Bergmann S, Strauss S, Bornstein TD, Licinio J, Wong ML, Birkenfeld AL, Bornstein SR.

Pharmacogenomics J. 2018 Apr;18(2):331-339. doi: 10.1038/tpj.2017.24. Epub 2017 Jun 13.

PMID:
28607507
41.

ANGPTL8 (Betatrophin) is Expressed in Visceral Adipose Tissue and Relates to Human Hepatic Steatosis in Two Independent Clinical Collectives.

von Loeffelholz C, Pfeiffer AFH, Lock JF, Lieske S, Döcke S, Murahovschi V, Kriebel J, de Las Heras Gala T, Grallert H, Rudovich N, Stockmann M, Spranger J, Jahreis G, Bornstein SR, Lau G, Xu A, Schulz-Menger J, Exner L, Haufe S, Jordan J, Engeli S, Birkenfeld AL.

Horm Metab Res. 2017 May;49(5):343-349. doi: 10.1055/s-0043-102950. Epub 2017 Mar 28.

PMID:
28351093
42.

The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism.

von Loeffelholz C, Lieske S, Neuschäfer-Rube F, Willmes DM, Raschzok N, Sauer IM, König J, Fromm MF, Horn P, Chatzigeorgiou A, Pathe-Neuschäfer-Rube A, Jordan J, Pfeiffer AFH, Mingrone G, Bornstein SR, Stroehle P, Harms C, Wunderlich FT, Helfand SL, Bernier M, de Cabo R, Shulman GI, Chavakis T, Püschel GP, Birkenfeld AL.

Hepatology. 2017 Aug;66(2):616-630. doi: 10.1002/hep.29089. Epub 2017 Jun 26.

43.

Comment on Ferrannini et al. CV Protection in the EMPA-REG OUTCOME Trial: A "Thrifty Substrate" Hypothesis. Diabetes Care 2016;39:1108-1114.

Jordan J, El-Armouche A, Hanefeld M, Bornstein SR, Birkenfeld AL.

Diabetes Care. 2016 Dec;39(12):e224-e225. No abstract available.

PMID:
27879363
44.

Inhibition of citrate cotransporter Slc13a5/mINDY by RNAi improves hepatic insulin sensitivity and prevents diet-induced non-alcoholic fatty liver disease in mice.

Brachs S, Winkel AF, Tang H, Birkenfeld AL, Brunner B, Jahn-Hofmann K, Margerie D, Ruetten H, Schmoll D, Spranger J.

Mol Metab. 2016 Aug 13;5(11):1072-1082. doi: 10.1016/j.molmet.2016.08.004. eCollection 2016 Nov.

45.

Serum and Plasma Levels of Vascular Endothelial Growth Factors in Relation to Quality of Glucose Control, Biomarkers of Inflammation, and Diabetic Nephropathy.

Hanefeld M, Appelt D, Engelmann K, Sandner D, Bornstein SR, Ganz X, Henkel E, Haase R, Birkenfeld AL.

Horm Metab Res. 2016 Sep;48(9):620. Epub 2016 Oct 18. No abstract available.

PMID:
27756080
46.

Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver.

von Loeffelholz C, Döcke S, Lock JF, Lieske S, Horn P, Kriebel J, Wahl S, Singmann P, de Las Heras Gala T, Grallert H, Raschzok N, Sauer IM, Heller R, Jahreis G, Claus RA, Bauer M, Stockmann M, Birkenfeld AL, Pfeiffer AFH.

Hepatol Res. 2017 Aug;47(9):890-901. doi: 10.1111/hepr.12825. Epub 2016 Nov 18.

PMID:
27689765
47.

Pharmacogenomics in type 2 diabetes: oral antidiabetic drugs.

Daniels MA, Kan C, Willmes DM, Ismail K, Pistrosch F, Hopkins D, Mingrone G, Bornstein SR, Birkenfeld AL.

Pharmacogenomics J. 2016 Oct;16(5):399-410. doi: 10.1038/tpj.2016.54. Epub 2016 Jul 19. Review.

PMID:
27432533
48.

Insulin Resistance, Microbiota, and Fat Distribution Changes by a New Model of Vertical Sleeve Gastrectomy in Obese Rats.

Basso N, Soricelli E, Castagneto-Gissey L, Casella G, Albanese D, Fava F, Donati C, Tuohy K, Angelini G, La Neve F, Severino A, Kamvissi-Lorenz V, Birkenfeld AL, Bornstein S, Manco M, Mingrone G.

Diabetes. 2016 Oct;65(10):2990-3001. doi: 10.2337/db16-0039. Epub 2016 Jul 18.

49.

Serum and Plasma Levels of Vascular Endothelial Growth Factors in Relation to Quality of Glucose Control, Biomarkers of Inflammation, and Diabetic Nephropathy.

Hanefeld M, Appelt D, Engelmann K, Sandner D, Bornstein SR, Ganz X, Henkel E, Haase R, Birkenfeld AL.

Horm Metab Res. 2016 Aug;48(8):529-34. doi: 10.1055/s-0042-106295. Epub 2016 Jul 7. Erratum in: Horm Metab Res. 2016 Sep;48(9):620.

PMID:
27388431
50.

Hypophosphatemia promotes lower rates of muscle ATP synthesis.

Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI.

FASEB J. 2016 Oct;30(10):3378-3387. Epub 2016 Jun 23.

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