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Items: 17

1.

MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.

Rocha AG, Franco A, Krezel AM, Rumsey JM, Alberti JM, Knight WC, Biris N, Zacharioudakis E, Janetka JW, Baloh RH, Kitsis RN, Mochly-Rosen D, Townsend RR, Gavathiotis E, Dorn GW 2nd.

Science. 2018 Apr 20;360(6386):336-341. doi: 10.1126/science.aao1785.

2.

Correcting mitochondrial fusion by manipulating mitofusin conformations.

Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW II.

Nature. 2016 Dec 1;540(7631):74-79. doi: 10.1038/nature20156. Epub 2016 Oct 24.

3.

Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation: DRUGGABILITY OF THE SMALL GTPase Rab27a.

Johnson JL, Ramadass M, He J, Brown SJ, Zhang J, Abgaryan L, Biris N, Gavathiotis E, Rosen H, Catz SD.

J Biol Chem. 2016 Dec 9;291(50):25965-25982. Epub 2016 Oct 4.

4.

Synthetic Antibodies Inhibit Bcl-2-associated X Protein (BAX) through Blockade of the N-terminal Activation Site.

Uchime O, Dai Z, Biris N, Lee D, Sidhu SS, Li S, Lai JR, Gavathiotis E.

J Biol Chem. 2016 Jan 1;291(1):89-102. doi: 10.1074/jbc.M115.680918. Epub 2015 Nov 12.

5.

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

Yudina Z, Roa A, Johnson R, Biris N, de Souza Aranha Vieira DA, Tsiperson V, Reszka N, Taylor AB, Hart PJ, Demeler B, Diaz-Griffero F, Ivanov DN.

Cell Rep. 2015 Aug 4;12(5):788-97. doi: 10.1016/j.celrep.2015.06.072. Epub 2015 Jul 23.

6.

Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core.

Biris N, Tomashevski A, Bhattacharya A, Diaz-Griffero F, Ivanov DN.

J Mol Biol. 2013 Dec 13;425(24):5032-44. doi: 10.1016/j.jmb.2013.07.025. Epub 2013 Jul 23.

7.

Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α.

Brandariz-Nuñez A, Roa A, Valle-Casuso JC, Biris N, Ivanov D, Diaz-Griffero F.

Virology. 2013 Jan 20;435(2):463-71. doi: 10.1016/j.virol.2012.09.042. Epub 2012 Oct 16.

8.

Structure of the rhesus monkey TRIM5α PRYSPRY domain, the HIV capsid recognition module.

Biris N, Yang Y, Taylor AB, Tomashevski A, Guo M, Hart PJ, Diaz-Griffero F, Ivanov DN.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13278-83. doi: 10.1073/pnas.1203536109. Epub 2012 Jul 30.

9.

Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes.

Romanuka J, Folkers GE, Biris N, Tishchenko E, Wienk H, Bonvin AM, Kaptein R, Boelens R.

J Mol Biol. 2009 Jul 17;390(3):478-89. doi: 10.1016/j.jmb.2009.05.022. Epub 2009 May 18.

PMID:
19450607
10.

A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription.

Wei Y, Liu S, Lausen J, Woodrell C, Cho S, Biris N, Kobayashi N, Wei Y, Yokoyama S, Werner MH.

Nat Struct Mol Biol. 2007 Jul;14(7):653-61. Epub 2007 Jun 17.

PMID:
17572682
11.

Disorder-order folding transitions underlie catalysis in the helicase motor of SecA.

Keramisanou D, Biris N, Gelis I, Sianidis G, Karamanou S, Economou A, Kalodimos CG.

Nat Struct Mol Biol. 2006 Jul;13(7):594-602. Epub 2006 Jun 18.

PMID:
16783375
12.

Influence of sequential oligopeptide carriers on the bioactive structure of conjugated epitopes: comparative study of the conformation of a Herpes simplex virus glycoprotein gD-1 epitope in the free and conjugated form, and protein "built-in" crystal structure.

Krikorian D, Stavrakoudis A, Biris N, Sakarellos C, Andreu D, de Oliveira E, Mezö G, Majer Z, Hudecz F, Welling-Wester S, Cung MT, Tsikaris V.

Biopolymers. 2006;84(4):383-99.

PMID:
16493659
13.
14.

Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.

Kalodimos CG, Biris N, Bonvin AM, Levandoski MM, Guennuegues M, Boelens R, Kaptein R.

Science. 2004 Jul 16;305(5682):386-9.

15.

Effect of synthetic peptides corresponding to residues 313-332 of the alphaIIb subunit on platelet activation and fibrinogen binding to alphaIIbbeta3.

Mitsios JV, Tambaki AP, Abatzis M, Biris N, Sakarellos-Daitsiotis M, Sakarellos C, Soteriadou K, Goudevenos J, Elisaf M, Tsoukatos D, Tsikaris V, Tselepis AD.

Eur J Biochem. 2004 Feb;271(4):855-62.

16.

Mapping the binding domains of the alpha(IIb) subunit. A study performed on the activated form of the platelet integrin alpha(IIb)beta(3).

Biris N, Abatzis M, Mitsios JV, Sakarellos-Daitsiotis M, Sakarellos C, Tsoukatos D, Tselepis AD, Michalis L, Sideris D, Konidou G, Soteriadou K, Tsikaris V.

Eur J Biochem. 2003 Sep;270(18):3760-7.

17.

The Ac-RGD-NH2 peptide as a probe of slow conformational exchange of short linear peptides in DMSO.

Biris N, Stavrakoudis A, Politou AS, Mikros E, Sakarellos-Daitsiotis M, Sakarellos C, Tsikaris V.

Biopolymers. 2003 May;69(1):72-86.

PMID:
12717723

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