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Items: 1 to 50 of 165

1.

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells.

Lahmann I, Bröhl D, Zyrianova T, Isomura A, Czajkowski MT, Kapoor V, Griger J, Ruffault PL, Mademtzoglou D, Zammit PS, Wunderlich T, Spuler S, Kühn R, Preibisch S, Wolf J, Kageyama R, Birchmeier C.

Genes Dev. 2019 May 1;33(9-10):524-535. doi: 10.1101/gad.322818.118. Epub 2019 Mar 12.

2.

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice.

Hernandez-Miranda LR, Ibrahim DM, Ruffault PL, Larrosa M, Balueva K, Müller T, Weerd W, Stolte-Dijkstra I, Hostra RMW, Brunet JF, Fortin G, Mundlos S, Birchmeier C.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13021-13026. doi: 10.1073/pnas.1813520115. Epub 2018 Nov 28.

3.

Haploinsufficiency of Insm1 Impairs Postnatal Baseline β-Cell Mass.

Tao W, Zhang Y, Ma L, Deng C, Duan H, Liang X, Liao R, Lin S, Nie T, Chen W, Wang C, Birchmeier C, Jia S.

Diabetes. 2018 Dec;67(12):2615-2625. doi: 10.2337/db17-1330. Epub 2018 Sep 26.

4.

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs.

Meyer K, Kirchner M, Uyar B, Cheng JY, Russo G, Hernandez-Miranda LR, Szymborska A, Zauber H, Rudolph IM, Willnow TE, Akalin A, Haucke V, Gerhardt H, Birchmeier C, Kühn R, Krauss M, Diecke S, Pascual JM, Selbach M.

Cell. 2018 Sep 20;175(1):239-253.e17. doi: 10.1016/j.cell.2018.08.019. Epub 2018 Sep 6.

PMID:
30197081
5.

Corrigendum: Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.

Kim M, Wende H, Walcher J, Kühnemund J, Cheret C, Kempa S, McShane E, Selbach M, Lewis GR, Birchmeier C.

Genes Dev. 2018 Aug 1;32(15-16):1101. doi: 10.1101/gad.318477.118. No abstract available.

6.

Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons.

Müller T, Braud S, Jüttner R, Voigt BC, Paulick K, Sheean ME, Klisch C, Gueneykaya D, Rathjen FG, Geiger JR, Poulet JF, Birchmeier C.

EMBO J. 2018 Sep 3;37(17). pii: e98858. doi: 10.15252/embj.201798858. Epub 2018 Jul 26.

7.

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells.

Kim M, Wende H, Walcher J, Kühnemund J, Cheret C, Kempa S, McShane E, Selbach M, Lewin GR, Birchmeier C.

Genes Dev. 2018 May 1;32(9-10):645-657. doi: 10.1101/gad.310490.117. Epub 2018 May 10. Erratum in: Genes Dev. 2018 Aug 1;32(15-16):1101.

8.

Sustained MAPK/ERK Activation in Adult Schwann Cells Impairs Nerve Repair.

Cervellini I, Galino J, Zhu N, Allen S, Birchmeier C, Bennett DL.

J Neurosci. 2018 Jan 17;38(3):679-690. doi: 10.1523/JNEUROSCI.2255-17.2017. Epub 2017 Dec 7.

9.

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest.

Espinosa-Medina I, Jevans B, Boismoreau F, Chettouh Z, Enomoto H, Müller T, Birchmeier C, Burns AJ, Brunet JF.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11980-11985. doi: 10.1073/pnas.1710308114. Epub 2017 Oct 24.

10.

RNA localization is a key determinant of neurite-enriched proteome.

Zappulo A, van den Bruck D, Ciolli Mattioli C, Franke V, Imami K, McShane E, Moreno-Estelles M, Calviello L, Filipchyk A, Peguero-Sanchez E, Müller T, Woehler A, Birchmeier C, Merino E, Rajewsky N, Ohler U, Mazzoni EO, Selbach M, Akalin A, Chekulaeva M.

Nat Commun. 2017 Sep 19;8(1):583. doi: 10.1038/s41467-017-00690-6.

11.

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.

Piwecka M, Glažar P, Hernandez-Miranda LR, Memczak S, Wolf SA, Rybak-Wolf A, Filipchyk A, Klironomos F, Cerda Jara CA, Fenske P, Trimbuch T, Zywitza V, Plass M, Schreyer L, Ayoub S, Kocks C, Kühn R, Rosenmund C, Birchmeier C, Rajewsky N.

Science. 2017 Sep 22;357(6357). pii: eaam8526. doi: 10.1126/science.aam8526. Epub 2017 Aug 10.

PMID:
28798046
12.

Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction.

Spielmann M, Hernandez-Miranda LR, Ceccherini I, Weese-Mayer DE, Kragesteen BK, Harabula I, Krawitz P, Birchmeier C, Leonard N, Mundlos S.

J Med Genet. 2017 Nov;54(11):754-761. doi: 10.1136/jmedgenet-2017-104765. Epub 2017 Aug 4.

PMID:
28779001
13.

Genetic identification of a hindbrain nucleus essential for innate vocalization.

Hernandez-Miranda LR, Ruffault PL, Bouvier JC, Murray AJ, Morin-Surun MP, Zampieri N, Cholewa-Waclaw JB, Ey E, Brunet JF, Champagnat J, Fortin G, Birchmeier C.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8095-8100. doi: 10.1073/pnas.1702893114. Epub 2017 Jul 11.

14.

BMP signaling regulates satellite cell-dependent postnatal muscle growth.

Stantzou A, Schirwis E, Swist S, Alonso-Martin S, Polydorou I, Zarrouki F, Mouisel E, Beley C, Julien A, Le Grand F, Garcia L, Colnot C, Birchmeier C, Braun T, Schuelke M, Relaix F, Amthor H.

Development. 2017 Aug 1;144(15):2737-2747. doi: 10.1242/dev.144089. Epub 2017 Jul 10.

15.

Cell fixation and preservation for droplet-based single-cell transcriptomics.

Alles J, Karaiskos N, Praktiknjo SD, Grosswendt S, Wahle P, Ruffault PL, Ayoub S, Schreyer L, Boltengagen A, Birchmeier C, Zinzen R, Kocks C, Rajewsky N.

BMC Biol. 2017 May 19;15(1):44. doi: 10.1186/s12915-017-0383-5.

16.

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence.

Griger J, Schneider R, Lahmann I, Schöwel V, Keller C, Spuler S, Nazare M, Birchmeier C.

Elife. 2017 May 2;6. pii: e21552. doi: 10.7554/eLife.21552.

17.

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.

Ravindran E, Hu H, Yuzwa SA, Hernandez-Miranda LR, Kraemer N, Ninnemann O, Musante L, Boltshauser E, Schindler D, Hübner A, Reinecker HC, Ropers HH, Birchmeier C, Miller FD, Wienker TF, Hübner C, Kaindl AM.

PLoS Genet. 2017 Apr 28;13(4):e1006746. doi: 10.1371/journal.pgen.1006746. eCollection 2017 Apr.

18.

Neuregulin-1 mutant mice indicate motor and sensory deficits, indeed few references for schizophrenia endophenotype model.

Schneider S, Götz K, Birchmeier C, Schwegler H, Roskoden T.

Behav Brain Res. 2017 Mar 30;322(Pt A):177-185. doi: 10.1016/j.bbr.2017.01.022. Epub 2017 Jan 13.

PMID:
28089851
19.

Touch Receptor-Derived Sensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination.

Arcourt A, Gorham L, Dhandapani R, Prato V, Taberner FJ, Wende H, Gangadharan V, Birchmeier C, Heppenstall PA, Lechner SG.

Neuron. 2017 Jan 4;93(1):179-193. doi: 10.1016/j.neuron.2016.11.027. Epub 2016 Dec 15.

20.

The dorsal spinal cord and hindbrain: From developmental mechanisms to functional circuits.

Hernandez-Miranda LR, Müller T, Birchmeier C.

Dev Biol. 2017 Dec 1;432(1):34-42. doi: 10.1016/j.ydbio.2016.10.008. Epub 2016 Oct 11. Review.

21.

Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.

Esteves de Lima J, Bonnin MA, Birchmeier C, Duprez D.

Elife. 2016 Aug 24;5. pii: e15593. doi: 10.7554/eLife.15593.

22.

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.

Bartus K, Galino J, James ND, Hernandez-Miranda LR, Dawes JM, Fricker FR, Garratt AN, McMahon SB, Ramer MS, Birchmeier C, Bennett DL, Bradbury EJ.

Brain. 2016 May;139(Pt 5):1394-416. doi: 10.1093/brain/aww039. Epub 2016 Mar 17.

23.

Neuregulin/ErbB Signaling in Developmental Myelin Formation and Nerve Repair.

Birchmeier C, Bennett DL.

Curr Top Dev Biol. 2016;116:45-64. doi: 10.1016/bs.ctdb.2015.11.009. Epub 2016 Feb 1. Review.

PMID:
26970613
24.

Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1.

Jia S, Wildner H, Birchmeier C.

Dev Biol. 2015 Dec 1;408(1):90-8. doi: 10.1016/j.ydbio.2015.10.009. Epub 2015 Oct 9.

25.

CO₂ in the spotlight.

Hernandez-Miranda LR, Birchmeier C.

Elife. 2015 May 13;4. doi: 10.7554/eLife.08086. No abstract available.

26.

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function.

Jia S, Ivanov A, Blasevic D, Müller T, Purfürst B, Sun W, Chen W, Poy MN, Rajewsky N, Birchmeier C.

EMBO J. 2015 May 12;34(10):1417-33. doi: 10.15252/embj.201490819. Epub 2015 Mar 31.

28.

Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.

Czajkowski MT, Rassek C, Lenhard DC, Bröhl D, Birchmeier C.

Dev Biol. 2014 Nov 15;395(2):307-16. doi: 10.1016/j.ydbio.2014.09.005. Epub 2014 Sep 16.

29.

Human satellite cells have regenerative capacity and are genetically manipulable.

Marg A, Escobar H, Gloy S, Kufeld M, Zacher J, Spuler A, Birchmeier C, Izsvák Z, Spuler S.

J Clin Invest. 2014 Oct;124(10):4257-65. doi: 10.1172/JCI63992. Epub 2014 Aug 26.

30.

Antagonistic regulation of p57kip2 by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest.

Zalc A, Hayashi S, Auradé F, Bröhl D, Chang T, Mademtzoglou D, Mourikis P, Yao Z, Cao Y, Birchmeier C, Relaix F.

Development. 2014 Jul;141(14):2780-90. doi: 10.1242/dev.110155.

31.

Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors.

Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Müller T, Birchmeier C, Fried K, Ernfors P, Adameyko I.

Science. 2014 Jul 4;345(6192):82-7. doi: 10.1126/science.1253281. Epub 2014 Jun 12.

32.

Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action.

Loos M, Mueller T, Gouwenberg Y, Wijnands R, van der Loo RJ; Neuro-BSIK Mouse Phenomics Consortium, Birchmeier C, Smit AB, Spijker S.

Biol Psychiatry. 2014 Oct 15;76(8):648-55. doi: 10.1016/j.biopsych.2014.02.011. Epub 2014 Feb 24.

PMID:
24703509
33.

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination.

Sheean ME, McShane E, Cheret C, Walcher J, Müller T, Wulf-Goldenberg A, Hoelper S, Garratt AN, Krüger M, Rajewsky K, Meijer D, Birchmeier W, Lewin GR, Selbach M, Birchmeier C.

Genes Dev. 2014 Feb 1;28(3):290-303. doi: 10.1101/gad.230045.113.

34.

Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors.

Welcker JE, Hernandez-Miranda LR, Paul FE, Jia S, Ivanov A, Selbach M, Birchmeier C.

Development. 2013 Dec;140(24):4947-58. doi: 10.1242/dev.097642. Epub 2013 Nov 13.

35.

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.

Grigoryan T, Stein S, Qi J, Wende H, Garratt AN, Nave KA, Birchmeier C, Birchmeier W.

Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18174-9. doi: 10.1073/pnas.1310490110. Epub 2013 Oct 22.

36.

Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities.

Xu Y, Lopes C, Wende H, Guo Z, Cheng L, Birchmeier C, Ma Q.

J Neurosci. 2013 Sep 11;33(37):14738-48. doi: 10.1523/JNEUROSCI.5512-12.2013.

37.

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.

Fricker FR, Antunes-Martins A, Galino J, Paramsothy R, La Russa F, Perkins J, Goldberg R, Brelstaff J, Zhu N, McMahon SB, Orengo C, Garratt AN, Birchmeier C, Bennett DL.

Brain. 2013 Jul;136(Pt 7):2279-97. doi: 10.1093/brain/awt148.

38.

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.

Cheret C, Willem M, Fricker FR, Wende H, Wulf-Goldenberg A, Tahirovic S, Nave KA, Saftig P, Haass C, Garratt AN, Bennett DL, Birchmeier C.

EMBO J. 2013 Jul 17;32(14):2015-28. doi: 10.1038/emboj.2013.146. Epub 2013 Jun 21.

39.

Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity.

Wildner H, Das Gupta R, Bröhl D, Heppenstall PA, Zeilhofer HU, Birchmeier C.

J Neurosci. 2013 Apr 24;33(17):7299-307. doi: 10.1523/JNEUROSCI.0491-13.2013.

40.

A validated regulatory network for Th17 cell specification.

Ciofani M, Madar A, Galan C, Sellars M, Mace K, Pauli F, Agarwal A, Huang W, Parkhurst CN, Muratet M, Newberry KM, Meadows S, Greenfield A, Yang Y, Jain P, Kirigin FK, Birchmeier C, Wagner EF, Murphy KM, Myers RM, Bonneau R, Littman DR.

Cell. 2012 Oct 12;151(2):289-303. doi: 10.1016/j.cell.2012.09.016. Epub 2012 Sep 25.

41.

Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on Notch signals.

Bröhl D, Vasyutina E, Czajkowski MT, Griger J, Rassek C, Rahn HP, Purfürst B, Wende H, Birchmeier C.

Dev Cell. 2012 Sep 11;23(3):469-81. doi: 10.1016/j.devcel.2012.07.014. Epub 2012 Aug 30.

42.

The transcription factor c-Maf in sensory neuron development.

Wende H, Lechner SG, Birchmeier C.

Transcription. 2012 Nov-Dec;3(6):285-9. doi: 10.4161/trns.21809. Epub 2012 Aug 14.

43.

The HGF receptor/Met tyrosine kinase is a key regulator of dendritic cell migration in skin immunity.

Baek JH, Birchmeier C, Zenke M, Hieronymus T.

J Immunol. 2012 Aug 15;189(4):1699-707. doi: 10.4049/jimmunol.1200729. Epub 2012 Jul 16.

44.

Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3.

Cadot B, Gache V, Vasyutina E, Falcone S, Birchmeier C, Gomes ER.

EMBO Rep. 2012 Aug;13(8):741-9. doi: 10.1038/embor.2012.89. Epub 2012 Jun 26.

45.

Uncoupling of PI3K from ErbB3 impairs mammary gland development but does not impact on ErbB2-induced mammary tumorigenesis.

Lahlou H, Müller T, Sanguin-Gendreau V, Birchmeier C, Muller WJ.

Cancer Res. 2012 Jun 15;72(12):3080-90. doi: 10.1158/0008-5472.CAN-11-3513. Epub 2012 Jun 4.

46.

A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis.

Simon R, Brylka H, Schwegler H, Venkataramanappa S, Andratschke J, Wiegreffe C, Liu P, Fuchs E, Jenkins NA, Copeland NG, Birchmeier C, Britsch S.

EMBO J. 2012 Jun 29;31(13):2922-36. doi: 10.1038/emboj.2012.142. Epub 2012 May 15.

47.

Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development.

John A, Brylka H, Wiegreffe C, Simon R, Liu P, Jüttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S.

Development. 2012 May;139(10):1831-41. doi: 10.1242/dev.072850. Epub 2012 Apr 4.

48.

The transcription factor c-Maf controls touch receptor development and function.

Wende H, Lechner SG, Cheret C, Bourane S, Kolanczyk ME, Pattyn A, Reuter K, Munier FL, Carroll P, Lewin GR, Birchmeier C.

Science. 2012 Mar 16;335(6074):1373-6. doi: 10.1126/science.1214314. Epub 2012 Feb 16.

49.

Targeting MET in cancer: rationale and progress.

Gherardi E, Birchmeier W, Birchmeier C, Vande Woude G.

Nat Rev Cancer. 2012 Jan 24;12(2):89-103. doi: 10.1038/nrc3205. Review. Erratum in: Nat Rev Cancer. 2012 Sep;12(9):637.

PMID:
22270953
50.

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.

Adameyko I, Lallemend F, Furlan A, Zinin N, Aranda S, Kitambi SS, Blanchart A, Favaro R, Nicolis S, Lübke M, Müller T, Birchmeier C, Suter U, Zaitoun I, Takahashi Y, Ernfors P.

Development. 2012 Jan;139(2):397-410. doi: 10.1242/dev.065581.

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