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Items: 17

1.

The biodistribution and clearance of AlbudAb, a novel biopharmaceutical medicine platform, assessed via PET imaging in humans.

Thorneloe KS, Sepp A, Zhang S, Galinanes-Garcia L, Galette P, Al-Azzam W, Vugts DJ, van Dongen G, Elsinga P, Wiegers J, Glaudemans AWJM, Vincent V, Renaux J, Szapacs M, Birchler M, Cleveland M, Bergstrom M, Davies M.

EJNMMI Res. 2019 May 21;9(1):45. doi: 10.1186/s13550-019-0514-9.

2.

Immunoassay methods used in clinical studies for the detection of anti-drug antibodies to adalimumab and infliximab.

Gorovits B, Baltrukonis DJ, Bhattacharya I, Birchler MA, Finco D, Sikkema D, Vincent MS, Lula S, Marshall L, Hickling TP.

Clin Exp Immunol. 2018 Jun;192(3):348-365. doi: 10.1111/cei.13112. Epub 2018 Mar 30. Review.

3.

Prediction of natalizumab anti-drug antibodies persistency.

Deisenhammer F, Jank M, Lauren A, Sjödin A, Ryner M, Fogdell-Hahn A, Sievers C, Lindberg R, Jensen PE, Sellebjerg F, Christodoulou L, Birchler M, Pallardy M, Auer M, Liblau R; ABIRISK consortium.

Mult Scler. 2019 Mar;25(3):392-398. doi: 10.1177/1352458517753721. Epub 2018 Jan 16.

PMID:
29336205
4.

Recommendations for the Assessment and Management of Pre-existing Drug-Reactive Antibodies During Biotherapeutic Development.

Xue L, Clements-Egan A, Amaravadi L, Birchler M, Gorovits B, Liang M, Myler H, Purushothama S, Manning MS, Sung C.

AAPS J. 2017 Nov;19(6):1576-1586. doi: 10.1208/s12248-017-0153-x. Epub 2017 Nov 6.

PMID:
29110222
5.

Pre-existing Antibody: Biotherapeutic Modality-Based Review.

Gorovits B, Clements-Egan A, Birchler M, Liang M, Myler H, Peng K, Purushothama S, Rajadhyaksha M, Salazar-Fontana L, Sung C, Xue L.

AAPS J. 2016 Mar;18(2):311-20. doi: 10.1208/s12248-016-9878-1. Epub 2016 Jan 28. Review.

6.

Specificity of human anti-variable heavy (VH ) chain autoantibodies and impact on the design and clinical testing of a VH domain antibody antagonist of tumour necrosis factor-α receptor 1.

Cordy JC, Morley PJ, Wright TJ, Birchler MA, Lewis AP, Emmins R, Chen YZ, Powley WM, Bareille PJ, Wilson R, Tonkyn J, Bayliffe AI, Lazaar AL.

Clin Exp Immunol. 2015 Nov;182(2):139-48. doi: 10.1111/cei.12680. Epub 2015 Sep 11.

7.

Autoantibodies to variable heavy (VH) chain Ig sequences in humans impact the safety and clinical pharmacology of a VH domain antibody antagonist of TNF-α receptor 1.

Holland MC, Wurthner JU, Morley PJ, Birchler MA, Lambert J, Albayaty M, Serone AP, Wilson R, Chen Y, Forrest RM, Cordy JC, Lipson DA, Bayliffe AI.

J Clin Immunol. 2013 Oct;33(7):1192-203. doi: 10.1007/s10875-013-9915-0. Epub 2013 Jul 6.

PMID:
23832582
8.

Exposure patterns of UV filters, fragrances, parabens, phthalates, organochlor pesticides, PBDEs, and PCBs in human milk: correlation of UV filters with use of cosmetics.

Schlumpf M, Kypke K, Wittassek M, Angerer J, Mascher H, Mascher D, Vökt C, Birchler M, Lichtensteiger W.

Chemosphere. 2010 Nov;81(10):1171-83. doi: 10.1016/j.chemosphere.2010.09.079. Epub 2010 Oct 27.

PMID:
21030064
9.

Immunoscintigraphy of patients with head and neck carcinomas, with an anti-angiogenetic antibody fragment.

Birchler MT, Thuerl C, Schmid D, Neri D, Waibel R, Schubiger A, Stoeckli SJ, Schmid S, Goerres GW.

Otolaryngol Head Neck Surg. 2007 Apr;136(4):543-8.

PMID:
17418248
10.

Kaposiform hemangioendothelioma arising in the ethmoid sinus of an 8-year-old girl with severe epistaxis.

Birchler MT, Schmid S, Holzmann D, Stallmach T, Gysin C.

Head Neck. 2006 Aug;28(8):761-4.

PMID:
16721737
11.

Tumor-targeting properties of novel antibodies specific to the large isoform of tenascin-C.

Brack SS, Silacci M, Birchler M, Neri D.

Clin Cancer Res. 2006 May 15;12(10):3200-8.

12.

Expression of the extra domain B of fibronectin, a marker of angiogenesis, in head and neck tumors.

Birchler MT, Milisavlijevic D, Pfaltz M, Neri D, Odermatt B, Schmid S, Stoeckli SJ.

Laryngoscope. 2003 Jul;113(7):1231-7.

PMID:
12838025
13.

Paraganglioma of the cervical sympathetic trunk.

Birchler MT, Landau K, Went PT, Stoeckli SJ.

Ann Otol Rhinol Laryngol. 2002 Dec;111(12 Pt 1):1087-91.

PMID:
12498369
14.

Infrared photodetection for the in vivo localisation of phage-derived antibodies directed against angiogenic markers.

Birchler M, Neri G, Tarli L, Halin C, Viti F, Neri D.

J Immunol Methods. 1999 Dec 10;231(1-2):239-48.

PMID:
10648941
15.

Effect of elevated levels of ornithine decarboxylase on cell cycle progression in skin.

Gilmour SK, Birchler M, Smith MK, Rayca K, Mostochuk J.

Cell Growth Differ. 1999 Nov;10(11):739-48.

16.

Selective targeting and photocoagulation of ocular angiogenesis mediated by a phage-derived human antibody fragment.

Birchler M, Viti F, Zardi L, Spiess B, Neri D.

Nat Biotechnol. 1999 Oct;17(10):984-8.

PMID:
10504699
17.

[Predictive role of IL-6 for multi-organ dysfunction syndrome MODS) in severely injured patients in the early intensive care phase].

Keel M, Birchler M, Wanner GA, Steckholzer U, Ertel W.

Langenbecks Arch Chir Suppl Kongressbd. 1998;115:1086-7. German.

PMID:
9931798

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