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Items: 1 to 50 of 90

1.

UVA-induced Carbon-Centered Radicals in Lightly Pigmented Cells detected using ESR Spectroscopy.

Kassouf N, Kay CWM, Volkov A, Chiang SC, Birch-Machin MA, El-Khamisy SF, Haywood RM.

Free Radic Biol Med. 2018 Jul 25. pii: S0891-5849(18)31279-6. doi: 10.1016/j.freeradbiomed.2018.07.019. [Epub ahead of print]

PMID:
30055236
2.

Optimised detection of mitochondrial DNA strand breaks.

Hanna R, Crowther JM, Bulsara PA, Wang X, Moore DJ, Birch-Machin MA.

Mitochondrion. 2018 May 4. pii: S1567-7249(17)30345-8. doi: 10.1016/j.mito.2018.04.009. [Epub ahead of print]

PMID:
29730480
3.

In vitro protective effects of an aqueous extract of Clitoria ternatea L. flower against hydrogen peroxide-induced cytotoxicity and UV-induced mtDNA damage in human keratinocytes.

Zakaria NNA, Okello EJ, Howes MJ, Birch-Machin MA, Bowman A.

Phytother Res. 2018 Jun;32(6):1064-1072. doi: 10.1002/ptr.6045. Epub 2018 Feb 21.

PMID:
29464849
4.

What is the role of mitochondrial dysfunction in skin photoaging?

Naidoo K, Hanna R, Birch-Machin MA.

Exp Dermatol. 2018 Feb;27(2):124-128. doi: 10.1111/exd.13476. Epub 2017 Dec 22.

PMID:
29197123
5.

Aware, motivated and striving for a 'safe tan': an exploratory mixed-method study of sun-protection during holidays.

Rodrigues AM, Sniehotta FF, Birch-Machin MA, Araujo-Soares V.

Health Psychol Behav Med. 2017 Jun 5;5(1):276-298. doi: 10.1080/21642850.2017.1335205. eCollection 2017.

6.

Systematic and Iterative Development of a Smartphone App to Promote Sun-Protection Among Holidaymakers: Design of a Prototype and Results of Usability and Acceptability Testing.

Rodrigues AM, Sniehotta FF, Birch-Machin MA, Olivier P, Araújo-Soares V.

JMIR Res Protoc. 2017 Jun 12;6(6):e112. doi: 10.2196/resprot.7172.

7.

Bad air gets under your skin.

Koohgoli R, Hudson L, Naidoo K, Wilkinson S, Chavan B, Birch-Machin MA.

Exp Dermatol. 2017 May;26(5):384-387. doi: 10.1111/exd.13257. Epub 2017 Feb 20.

PMID:
27892609
8.

Oxidative stress and ageing.

Birch-Machin MA, Bowman A.

Br J Dermatol. 2016 Oct;175 Suppl 2:26-29. doi: 10.1111/bjd.14906. Review.

PMID:
27667312
9.

Mitochondrial damage and ageing using skin as a model organ.

Hudson L, Bowman A, Rashdan E, Birch-Machin MA.

Maturitas. 2016 Nov;93:34-40. doi: 10.1016/j.maturitas.2016.04.021. Epub 2016 May 7. Review.

PMID:
27215947
10.

Age-Dependent Decrease of Mitochondrial Complex II Activity in Human Skin Fibroblasts.

Bowman A, Birch-Machin MA.

J Invest Dermatol. 2016 May;136(5):912-9. doi: 10.1016/j.jid.2016.01.017. Epub 2016 Jan 29.

11.

Oxidative stress--a key emerging impact factor in health, ageing, lifestyle and aesthetics.

Kandola K, Bowman A, Birch-Machin MA.

Int J Cosmet Sci. 2015 Dec;37 Suppl 2:1-8. doi: 10.1111/ics.12287. Review.

PMID:
26574299
12.

Mitochondria-targeted antioxidants.

Oyewole AO, Birch-Machin MA.

FASEB J. 2015 Dec;29(12):4766-71. doi: 10.1096/fj.15-275404. Epub 2015 Aug 7. Review.

PMID:
26253366
13.

Determination of the Action Spectrum of UVR-Induced Mitochondrial DNA Damage in Human Skin Cells.

Latimer JA, Lloyd JJ, Diffey BL, Matts PJ, Birch-Machin MA.

J Invest Dermatol. 2015 Oct;135(10):2512-2518. doi: 10.1038/jid.2015.194. Epub 2015 Jun 1.

14.

Sebum, inflammasomes and the skin: current concepts and future perspective.

Oyewole AO, Birch-Machin MA.

Exp Dermatol. 2015 Sep;24(9):651-4. doi: 10.1111/exd.12774. Epub 2015 Jul 14.

PMID:
26014614
15.

Mitochondrial DNA as a biosensor of UV exposure in human skin.

Bowman A, Birch-Machin MA.

Methods Mol Biol. 2015;1265:379-88. doi: 10.1007/978-1-4939-2288-8_27.

PMID:
25634289
16.

A role for human mitochondrial complex II in the production of reactive oxygen species in human skin.

Anderson A, Bowman A, Boulton SJ, Manning P, Birch-Machin MA.

Redox Biol. 2014;2:1016-22. doi: 10.1016/j.redox.2014.08.005. Epub 2014 Aug 28.

17.

Skin manifestations of mitochondrial dysfunction: more important than previously thought.

Boulton SJ, Bowman A, Koohgoli R, Birch-Machin MA.

Exp Dermatol. 2015 Jan;24(1):12-3. doi: 10.1111/exd.12597. No abstract available.

PMID:
25403780
18.

Impact of hyperpigmentation on superoxide flux and melanoma cell metabolism at mitochondrial complex II.

Boulton SJ, Birch-Machin MA.

FASEB J. 2015 Jan;29(1):346-53. doi: 10.1096/fj.14-261982. Epub 2014 Oct 28.

PMID:
25351989
19.

Comparing the effects of mitochondrial targeted and localized antioxidants with cellular antioxidants in human skin cells exposed to UVA and hydrogen peroxide.

Oyewole AO, Wilmot MC, Fowler M, Birch-Machin MA.

FASEB J. 2014 Jan;28(1):485-94. doi: 10.1096/fj.13-237008. Epub 2013 Oct 10.

PMID:
24115050
20.

Whales use distinct strategies to counteract solar ultraviolet radiation.

Martinez-Levasseur LM, Birch-Machin MA, Bowman A, Gendron D, Weatherhead E, Knell RJ, Acevedo-Whitehouse K.

Sci Rep. 2013;3:2386. doi: 10.1038/srep02386.

21.

Mitochondrial DNA damage as a biomarker for ultraviolet radiation exposure and oxidative stress.

Birch-Machin MA, Russell EV, Latimer JA.

Br J Dermatol. 2013 Jul;169 Suppl 2:9-14. doi: 10.1111/bjd.12207. Review.

PMID:
23786615
22.

The simultaneous detection of mitochondrial DNA damage from sun-exposed skin of three whale species and its association with UV-induced microscopic lesions and apoptosis.

Bowman A, Martinez-Levasseur LM, Acevedo-Whitehouse K, Gendron D, Birch-Machin MA.

Mitochondrion. 2013 Jul;13(4):342-9. doi: 10.1016/j.mito.2013.04.003. Epub 2013 Apr 11.

PMID:
23583579
23.

Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy.

Wright TJ, McKee C, Birch-Machin MA, Ellis R, Armstrong JL, Lovat PE.

Clin Exp Dermatol. 2013 Jun;38(4):421-3. doi: 10.1111/ced.12138. Epub 2013 Mar 27.

PMID:
23530461
24.

Stressed out mitochondria: the role of mitochondria in ageing and cancer focussing on strategies and opportunities in human skin.

Tulah AS, Birch-Machin MA.

Mitochondrion. 2013 Sep;13(5):444-53. doi: 10.1016/j.mito.2012.11.007. Epub 2012 Nov 27. Review.

PMID:
23195682
25.

Investigating the role of melanin in UVA/UVB- and hydrogen peroxide-induced cellular and mitochondrial ROS production and mitochondrial DNA damage in human melanoma cells.

Swalwell H, Latimer J, Haywood RM, Birch-Machin MA.

Free Radic Biol Med. 2012 Feb 1;52(3):626-634. doi: 10.1016/j.freeradbiomed.2011.11.019. Epub 2011 Dec 8.

PMID:
22178978
26.

Implications of using the fluorescent probes, dihydrorhodamine 123 and 2',7'-dichlorodihydrofluorescein diacetate, for the detection of UVA-induced reactive oxygen species.

Boulton S, Anderson A, Swalwell H, Henderson JR, Manning P, Birch-Machin MA.

Free Radic Res. 2011 Feb;45(2):139-46. doi: 10.3109/10715762.2010.517751. Epub 2010 Oct 13.

PMID:
20942573
27.

Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial.

Rizwan M, Rodriguez-Blanco I, Harbottle A, Birch-Machin MA, Watson RE, Rhodes LE.

Br J Dermatol. 2011 Jan;164(1):154-62. doi: 10.1111/j.1365-2133.2010.10057.x. Epub 2010 Nov 29.

PMID:
20854436
28.

Real-time polymerase chain reaction analysis of a 3895-bp mitochondrial DNA deletion in epithelial swabs and its use as a quantitative marker for sunlight exposure in human skin.

Harbottle A, Maki J, Reguly B, Wittock R, Robinson K, Parr R, Birch-Machin MA.

Br J Dermatol. 2010 Dec;163(6):1291-5. doi: 10.1111/j.1365-2133.2010.10001.x. Epub 2010 Nov 8.

PMID:
20731654
29.

Targeting GRP78 to enhance melanoma cell death.

Martin S, Hill DS, Paton JC, Paton AW, Birch-Machin MA, Lovat PE, Redfern CP.

Pigment Cell Melanoma Res. 2010 Oct;23(5):675-82. doi: 10.1111/j.1755-148X.2010.00731.x. Epub 2010 Jul 12.

30.

How mitochondria record the effects of UV exposure and oxidative stress using human skin as a model tissue.

Birch-Machin MA, Swalwell H.

Mutagenesis. 2010 Mar;25(2):101-7. doi: 10.1093/mutage/gep061. Epub 2009 Dec 2. Review.

PMID:
19955330
31.

Direct, real-time monitoring of superoxide generation in isolated mitochondria.

Henderson JR, Swalwell H, Boulton S, Manning P, McNeil CJ, Birch-Machin MA.

Free Radic Res. 2009 Sep;43(9):796-802. doi: 10.1080/10715760903062895. Epub 2009 Jun 25.

PMID:
19562601
32.

Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma.

Hill DS, Martin S, Armstrong JL, Flockhart R, Tonison JJ, Simpson DG, Birch-Machin MA, Redfern CP, Lovat PE.

Clin Cancer Res. 2009 Feb 15;15(4):1192-8. doi: 10.1158/1078-0432.CCR-08-2150.

33.

The relationship between the aging- and photo-dependent T414G mitochondrial DNA mutation with cellular senescence and reactive oxygen species production in cultured skin fibroblasts.

Birket MJ, Passos JF, von Zglinicki T, Birch-Machin MA.

J Invest Dermatol. 2009 Jun;129(6):1361-6. doi: 10.1038/jid.2008.373. Epub 2008 Dec 4.

34.

Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.

Lovat PE, Corazzari M, Armstrong JL, Martin S, Pagliarini V, Hill D, Brown AM, Piacentini M, Birch-Machin MA, Redfern CP.

Cancer Res. 2008 Jul 1;68(13):5363-9. doi: 10.1158/0008-5472.CAN-08-0035.

35.

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.

Ahmed S, Passos JF, Birket MJ, Beckmann T, Brings S, Peters H, Birch-Machin MA, von Zglinicki T, Saretzki G.

J Cell Sci. 2008 Apr 1;121(Pt 7):1046-53. doi: 10.1242/jcs.019372. Epub 2008 Mar 11.

36.

Management of field change in actinic keratosis.

Vatve M, Ortonne JP, Birch-Machin MA, Gupta G.

Br J Dermatol. 2007 Dec;157 Suppl 2:21-4. Review.

PMID:
18067627
37.

Direct monitoring of UV-induced free radical generation in HaCaT keratinocytes.

Aitken GR, Henderson JR, Chang SC, McNeil CJ, Birch-Machin MA.

Clin Exp Dermatol. 2007 Nov;32(6):722-7.

PMID:
17953641
38.

The mitochondrial genome: a biosensor for early cancer detection?

Parr RL, Jakupciak JP, Birch-Machin MA, Dakubo GD.

Expert Opin Med Diagn. 2007 Oct;1(2):169-82. doi: 10.1517/17530059.1.2.169.

PMID:
23489304
39.
40.

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.

Passos JF, Saretzki G, Ahmed S, Nelson G, Richter T, Peters H, Wappler I, Birket MJ, Harold G, Schaeuble K, Birch-Machin MA, Kirkwood TB, von Zglinicki T.

PLoS Biol. 2007 May;5(5):e110.

41.

Clinical implications and utility of field cancerization.

Dakubo GD, Jakupciak JP, Birch-Machin MA, Parr RL.

Cancer Cell Int. 2007 Mar 15;7:2.

42.

Somatic mitochondrial DNA mutations in prostate cancer and normal appearing adjacent glands in comparison to age-matched prostate samples without malignant histology.

Parr RL, Dakubo GD, Crandall KA, Maki J, Reguly B, Aguirre A, Wittock R, Robinson K, Alexander JS, Birch-Machin MA, Abdel-Malak M, Froberg MK, Diamandis EP, Thayer RE.

J Mol Diagn. 2006 Jul;8(3):312-9.

43.

Towards a "free radical theory of graying": melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage.

Arck PC, Overall R, Spatz K, Liezman C, Handjiski B, Klapp BF, Birch-Machin MA, Peters EM.

FASEB J. 2006 Jul;20(9):1567-9. Epub 2006 May 24.

PMID:
16723385
45.

The role of mitochondria in ageing and carcinogenesis.

Birch-Machin MA.

Clin Exp Dermatol. 2006 Jul;31(4):548-52. Review.

PMID:
16716161
46.

Mitochondrial DNA as a potential tool for early cancer detection.

Parr RL, Dakubo GD, Thayer RE, McKenney K, Birch-Machin MA.

Hum Genomics. 2006 Jan;2(4):252-7.

48.

Using mitochondrial DNA as a biosensor of early cancer development.

Birch-Machin MA.

Br J Cancer. 2005 Aug 8;93(3):271-2. Review. No abstract available.

49.
50.

The use of a 3895 bp mitochondrial DNA deletion as a marker for sunlight exposure in human skin.

Krishnan KJ, Harbottle A, Birch-Machin MA.

J Invest Dermatol. 2004 Dec;123(6):1020-4. Erratum in: J Invest Dermatol. 2005 May;124(5):1092.

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