Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 79


Tumor-Derived Thymic Stromal Lymphopoietin Expands Bone Marrow B-cell Precursors in Circulation to Support Metastasis.

Ragonnaud E, Moritoh K, Bodogai M, Gusev F, Garaud S, Chen C, Wang X, Baljinnyam T, Becker KG, Maul RW, Willard-Gallo K, Rogaev E, Biragyn A.

Cancer Res. 2019 Nov 15;79(22):5826-5838. doi: 10.1158/0008-5472.CAN-19-1058. Epub 2019 Oct 1.


Correction to: Potential importance of B cells in aging and aging-associated neurodegenerative diseases.

Biragyn A, Aliseychik M, Rogaev E.

Semin Immunopathol. 2019 Mar;41(2):277. doi: 10.1007/s00281-018-00729-w.


Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells.

Bodogai M, O'Connell J, Kim K, Kim Y, Moritoh K, Chen C, Gusev F, Vaughan K, Shulzhenko N, Mattison JA, Lee-Chang C, Chen W, Carlson O, Becker KG, Gurung M, Morgun A, White J, Meade T, Perdue K, Mack M, Ferrucci L, Trinchieri G, de Cabo R, Rogaev E, Egan J, Wu J, Biragyn A.

Sci Transl Med. 2018 Nov 14;10(467). pii: eaat4271. doi: 10.1126/scitranslmed.aat4271.


Restoring microglial and astroglial homeostasis using DNA immunization in a Down Syndrome mouse model.

Illouz T, Madar R, Biragyn A, Okun E.

Brain Behav Immun. 2019 Jan;75:163-180. doi: 10.1016/j.bbi.2018.10.004. Epub 2018 Oct 25.


SCAMP4 enhances the senescent cell secretome.

Kim KM, Noh JH, Bodogai M, Martindale JL, Pandey PR, Yang X, Biragyn A, Abdelmohsen K, Gorospe M.

Genes Dev. 2018 Jul 1;32(13-14):909-914. doi: 10.1101/gad.313270.118.


Gut dysbiosis: a potential link between increased cancer risk in ageing and inflammaging.

Biragyn A, Ferrucci L.

Lancet Oncol. 2018 Jun;19(6):e295-e304. doi: 10.1016/S1470-2045(18)30095-0. Epub 2018 Jun 1. Review.


Altered Extracellular Vesicle Concentration, Cargo, and Function in Diabetes.

Freeman DW, Noren Hooten N, Eitan E, Green J, Mode NA, Bodogai M, Zhang Y, Lehrmann E, Zonderman AB, Biragyn A, Egan J, Becker KG, Mattson MP, Ejiogu N, Evans MK.

Diabetes. 2018 Nov;67(11):2377-2388. doi: 10.2337/db17-1308. Epub 2018 May 2.


Identification of senescent cell surface targetable protein DPP4.

Kim KM, Noh JH, Bodogai M, Martindale JL, Yang X, Indig FE, Basu SK, Ohnuma K, Morimoto C, Johnson PF, Biragyn A, Abdelmohsen K, Gorospe M.

Genes Dev. 2017 Aug 1;31(15):1529-1534. doi: 10.1101/gad.302570.117. Epub 2017 Sep 6.


Correction for Lu et al., "Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair".

Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S.

Mol Cell Biol. 2017 Aug 11;37(17). pii: e00310-17. doi: 10.1128/MCB.00310-17. Print 2017 Sep 1. No abstract available.


Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes.

Eitan E, Green J, Bodogai M, Mode NA, Bæk R, Jørgensen MM, Freeman DW, Witwer KW, Zonderman AB, Biragyn A, Mattson MP, Noren Hooten N, Evans MK.

Sci Rep. 2017 May 2;7(1):1342. doi: 10.1038/s41598-017-01386-z.


Potential importance of B cells in aging and aging-associated neurodegenerative diseases.

Biragyn A, Aliseychik M, Rogaev E.

Semin Immunopathol. 2017 Apr;39(3):283-294. doi: 10.1007/s00281-016-0615-8. Epub 2017 Jan 12. Review. Erratum in: Semin Immunopathol. 2019 Jan 14;:.


Fusion of the dendritic cell-targeting chemokine MIP3α to melanoma antigen Gp100 in a therapeutic DNA vaccine significantly enhances immunogenicity and survival in a mouse melanoma model.

Gordy JT, Luo K, Zhang H, Biragyn A, Markham RB.

J Immunother Cancer. 2016 Dec 20;4:96. doi: 10.1186/s40425-016-0189-y. eCollection 2016.


Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers.

Lee-Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, Young HA, Croft M, Ferrucci L, Biragyn A.

J Immunol. 2016 Apr 15;196(8):3385-97. doi: 10.4049/jimmunol.1502034. Epub 2016 Mar 16.


Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo.

Hiyoshi M, Okuma K, Tateyama S, Takizawa K, Saito M, Kuramitsu M, Araki K, Morishita K, Okada S, Yamamoto N, Biragyn A, Yamaguchi K, Hamaguchi I.

Retrovirology. 2015 Aug 20;12:73. doi: 10.1186/s12977-015-0199-8.


Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells.

Bodogai M, Moritoh K, Lee-Chang C, Hollander CM, Sherman-Baust CA, Wersto RP, Araki Y, Miyoshi I, Yang L, Trinchieri G, Biragyn A.

Cancer Res. 2015 Sep 1;75(17):3456-65. doi: 10.1158/0008-5472.CAN-14-3077. Epub 2015 Jul 16.


The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.

Youm YH, Nguyen KY, Grant RW, Goldberg EL, Bodogai M, Kim D, D'Agostino D, Planavsky N, Lupfer C, Kanneganti TD, Kang S, Horvath TL, Fahmy TM, Crawford PA, Biragyn A, Alnemri E, Dixit VD.

Nat Med. 2015 Mar;21(3):263-9. doi: 10.1038/nm.3804. Epub 2015 Feb 16.


Nuclear GIT2 is an ATM substrate and promotes DNA repair.

Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S.

Mol Cell Biol. 2015 Apr;35(7):1081-96. doi: 10.1128/MCB.01432-14. Epub 2015 Jan 20. Erratum in: Mol Cell Biol. 2017 Aug 11;37(17 ):.


Antiviral activity of a single-domain antibody immunotoxin binding to glycoprotein D of herpes simplex virus 2.

Geoghegan EM, Zhang H, Desai PJ, Biragyn A, Markham RB.

Antimicrob Agents Chemother. 2015 Jan;59(1):527-35. doi: 10.1128/AAC.03818-14. Epub 2014 Nov 10.


Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease.

Kapogiannis D, Boxer A, Schwartz JB, Abner EL, Biragyn A, Masharani U, Frassetto L, Petersen RC, Miller BL, Goetzl EJ.

FASEB J. 2015 Feb;29(2):589-96. doi: 10.1096/fj.14-262048. Epub 2014 Oct 23.


Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity.

Lee-Chang C, Bodogai M, Moritoh K, Olkhanud PB, Chan AC, Croft M, Mattison JA, Holst PJ, Gress RE, Ferrucci L, Hakim F, Biragyn A.

Blood. 2014 Aug 28;124(9):1450-9. doi: 10.1182/blood-2014-03-563940. Epub 2014 Jul 18.


Generation and identification of tumor-evoked regulatory B cells.

Biragyn A, Lee-Chang C, Bodogai M.

Methods Mol Biol. 2014;1190:271-89. doi: 10.1007/978-1-4939-1161-5_19.


Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilities.

Luo K, Zhang H, Zavala F, Biragyn A, Espinosa DA, Markham RB.

PLoS One. 2014 Mar 5;9(3):e90413. doi: 10.1371/journal.pone.0090413. eCollection 2014.


Targeted reduction of CCR4⁺ cells is sufficient to suppress allergic airway inflammation.

Honjo A, Ogawa H, Azuma M, Tezuka T, Sone S, Biragyn A, Nishioka Y.

Respir Investig. 2013 Dec;51(4):241-9. doi: 10.1016/j.resinv.2013.04.007. Epub 2013 Jun 22.


Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells.

Lee-Chang C, Bodogai M, Martin-Montalvo A, Wejksza K, Sanghvi M, Moaddel R, de Cabo R, Biragyn A.

J Immunol. 2013 Oct 15;191(8):4141-51. doi: 10.4049/jimmunol.1300606. Epub 2013 Sep 16.


Inhibition of lung metastasis by chemokine CCL17-mediated in vivo silencing of genes in CCR4+ Tregs.

Biragyn A, Bodogai M, Olkhanud PB, Denny-Brown SR, Puri N, Ayukawa K, Kanegasaki S, Hogaboam CM, Wejksza K, Lee-Chang C.

J Immunother. 2013 May;36(4):258-67. doi: 10.1097/CJI.0b013e318294357c.


Cancer-produced metabolites of 5-lipoxygenase induce tumor-evoked regulatory B cells via peroxisome proliferator-activated receptor α.

Wejksza K, Lee-Chang C, Bodogai M, Bonzo J, Gonzalez FJ, Lehrmann E, Becker K, Biragyn A.

J Immunol. 2013 Mar 15;190(6):2575-84. doi: 10.4049/jimmunol.1201920. Epub 2013 Feb 13.


Anti-CD20 antibody promotes cancer escape via enrichment of tumor-evoked regulatory B cells expressing low levels of CD20 and CD137L.

Bodogai M, Lee Chang C, Wejksza K, Lai J, Merino M, Wersto RP, Gress RE, Chan AC, Hesdorffer C, Biragyn A.

Cancer Res. 2013 Apr 1;73(7):2127-38. doi: 10.1158/0008-5472.CAN-12-4184. Epub 2013 Jan 30.


Prime-boost BCG vaccination with DNA vaccines based in β-defensin-2 and mycobacterial antigens ESAT6 or Ag85B improve protection in a tuberculosis experimental model.

Cervantes-Villagrana AR, Hernández-Pando R, Biragyn A, Castañeda-Delgado J, Bodogai M, Martínez-Fierro M, Sada E, Trujillo V, Enciso-Moreno A, Rivas-Santiago B.

Vaccine. 2013 Jan 11;31(4):676-84. doi: 10.1016/j.vaccine.2012.11.042. Epub 2012 Nov 26.


A new paradigm for an old story: the role of regulatory B cells in cancer.

Biragyn A, Lee-Chang C.

Front Immunol. 2012 Jul 23;3:206. doi: 10.3389/fimmu.2012.00206. eCollection 2012. No abstract available.


Neoplastic "Black Ops": cancer's subversive tactics in overcoming host defenses.

Biragyn A, Longo DL.

Semin Cancer Biol. 2012 Feb;22(1):50-9. doi: 10.1016/j.semcancer.2012.01.005. Epub 2012 Jan 12. Review.


DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.

Olkhanud PB, Mughal M, Ayukawa K, Malchinkhuu E, Bodogai M, Feldman N, Rothman S, Lee JH, Chigurupati S, Okun E, Nagashima K, Mattson MP, Biragyn A.

Vaccine. 2012 Feb 21;30(9):1650-8. doi: 10.1016/j.vaccine.2011.12.136. Epub 2012 Jan 14.


Distinctive immunoregulatory effects of adenosine on T cells of older humans.

Hesdorffer CS, Malchinkhuu E, Biragyn A, Mabrouk OS, Kennedy RT, Madara K, Taub DD, Longo DL, Schwartz JB, Ferrucci L, Goetzl EJ.

FASEB J. 2012 Mar;26(3):1301-10. doi: 10.1096/fj.11-197046. Epub 2011 Nov 25.


Thymic stromal lymphopoietin is a key mediator of breast cancer progression.

Olkhanud PB, Rochman Y, Bodogai M, Malchinkhuu E, Wejksza K, Xu M, Gress RE, Hesdorffer C, Leonard WJ, Biragyn A.

J Immunol. 2011 May 15;186(10):5656-62. doi: 10.4049/jimmunol.1100463. Epub 2011 Apr 13.


Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4⁺ T cells to T-regulatory cells.

Olkhanud PB, Damdinsuren B, Bodogai M, Gress RE, Sen R, Wejksza K, Malchinkhuu E, Wersto RP, Biragyn A.

Cancer Res. 2011 May 15;71(10):3505-15. doi: 10.1158/0008-5472.CAN-10-4316. Epub 2011 Mar 28.


Breast cancer lung metastasis requires expression of chemokine receptor CCR4 and regulatory T cells.

Olkhanud PB, Baatar D, Bodogai M, Hakim F, Gress R, Anderson RL, Deng J, Xu M, Briest S, Biragyn A.

Cancer Res. 2009 Jul 15;69(14):5996-6004. doi: 10.1158/0008-5472.CAN-08-4619. Epub 2009 Jun 30.


Tregs utilize beta-galactoside-binding protein to transiently inhibit PI3K/p21ras activity of human CD8+ T cells to block their TCR-mediated ERK activity and proliferation.

Baatar D, Olkhanud PB, Wells V, Indig FE, Mallucci L, Biragyn A.

Brain Behav Immun. 2009 Oct;23(7):1028-37. doi: 10.1016/j.bbi.2009.06.003. Epub 2009 Jun 9.


Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4+ and CD8+ T cells.

Almanzar G, Olkhanud PB, Bodogai M, Dell'agnola C, Baatar D, Hewitt SM, Ghimenton C, Tummala MK, Weeraratna AT, Hoek KS, Kouprina N, Larionov V, Biragyn A.

Clin Cancer Res. 2009 Mar 15;15(6):1954-63. doi: 10.1158/1078-0432.CCR-08-1290. Epub 2009 Mar 10.


Potent human monoclonal antibodies against SARS CoV, Nipah and Hendra viruses.

Prabakaran P, Zhu Z, Xiao X, Biragyn A, Dimitrov AS, Broder CC, Dimitrov DS.

Expert Opin Biol Ther. 2009 Mar;9(3):355-68. doi: 10.1517/14712590902763755 . Review. Erratum in: Expert Opin Biol Ther. 2009 Apr;9(4):533.


Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.

Dissanayake SK, Olkhanud PB, O'Connell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM, Weeraratna AT.

Cancer Res. 2008 Dec 15;68(24):10205-14. doi: 10.1158/0008-5472.CAN-08-2149.


Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck.

Ghosh MC, Baatar D, Collins G, Carter A, Indig F, Biragyn A, Taub DD.

Blood. 2009 Jan 15;113(3):575-84. doi: 10.1182/blood-2008-04-151803. Epub 2008 Oct 7.


Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.

Movsesyan N, Ghochikyan A, Mkrtichyan M, Petrushina I, Davtyan H, Olkhanud PB, Head E, Biragyn A, Cribbs DH, Agadjanyan MG.

PLoS One. 2008 May 7;3(5):e2124. doi: 10.1371/journal.pone.0002124.


Models for lymphoma.

Biragyn A, Kwak LW.

Curr Protoc Immunol. 2002 Feb;Chapter 20:Unit 20.6. doi: 10.1002/0471142735.im2006s46.


Murine beta-defensin 2 promotes TLR-4/MyD88-mediated and NF-kappaB-dependent atypical death of APCs via activation of TNFR2.

Biragyn A, Coscia M, Nagashima K, Sanford M, Young HA, Olkhanud P.

J Leukoc Biol. 2008 Apr;83(4):998-1008. doi: 10.1189/jlb.1007700. Epub 2008 Jan 11.


CCR4-expressing T cell tumors can be specifically controlled via delivery of toxins to chemokine receptors.

Baatar D, Olkhanud P, Newton D, Sumitomo K, Biragyn A.

J Immunol. 2007 Aug 1;179(3):1996-2004.


Tumor-associated embryonic antigen-expressing vaccines that target CCR6 elicit potent CD8+ T cell-mediated protective and therapeutic antitumor immunity.

Biragyn A, Schiavo R, Olkhanud P, Sumitomo K, King A, McCain M, Indig FE, Almanzar G, Baatar D.

J Immunol. 2007 Jul 15;179(2):1381-8.


Clinical utilization of chemokines to combat cancer: the double-edged sword.

Dell'Agnola C, Biragyn A.

Expert Rev Vaccines. 2007 Apr;6(2):267-83. Review.


Cloning of B cell lymphoma-associated antigens using modified phage-displayed expression cDNA library and immunized patient sera.

Cha SC, Kwak LW, Ruffini PA, Qin H, Neelapu S, Biragyn A.

J Immunol Methods. 2006 May 30;312(1-2):79-93. Epub 2006 Mar 31.


Chemokine receptor targeting efficiently directs antigens to MHC class I pathways and elicits antigen-specific CD8+ T-cell responses.

Schiavo R, Baatar D, Olkhanud P, Indig FE, Restifo N, Taub D, Biragyn A.

Blood. 2006 Jun 15;107(12):4597-605. Epub 2006 Mar 2.


Rationale for dendritic cell-based vaccines for acute myeloid leukemia.

Biragyn A.

Haematologica. 2005 Aug;90(8):1010C. No abstract available.


Supplemental Content

Loading ...
Support Center