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Items: 1 to 50 of 396

1.

Clinical impact of genomic diversity from early to advanced hepatocellular carcinoma.

Nault JC, Martin Y, Caruso S, Hirsch TZ, Bayard Q, Calderaro J, Charpy C, Copie-Bergman C, Ziol M, Bioulac-Sage P, Couchy G, Blanc JF, Nahon P, Amaddeo G, Ganne-Carrie N, Morcrette G, Chiche L, Duvoux C, Faivre S, Laurent A, Imbeaud S, Rebouissou S, Llovet J, Seror O, Letouzé E, Zucman-Rossi J.

Hepatology. 2019 Jun 17. doi: 10.1002/hep.30811. [Epub ahead of print]

PMID:
31206197
2.

Analysis of Liver Cancer Cell Lines Identifies Agents With Likely Efficacy Against Hepatocellular Carcinoma and Markers of Response.

Caruso S, Calatayud AL, Pilet J, La Bella T, Rekik S, Imbeaud S, Letouzé E, Meunier L, Bayard Q, Rohr-Udilova N, Péneau C, Grasl-Kraupp B, de Koning L, Ouine B, Bioulac-Sage P, Couchy G, Calderaro J, Nault JC, Zucman-Rossi J, Rebouissou S.

Gastroenterology. 2019 May 4. pii: S0016-5085(19)36771-X. doi: 10.1053/j.gastro.2019.05.001. [Epub ahead of print]

PMID:
31063779
3.

Unclassified hepatocellular adenoma expressing ASS1 associated with inflammatory hepatocellular adenomas.

Frulio N, Balabaud C, Laurent C, Trillaud H, Bioulac-Sage P.

Clin Res Hepatol Gastroenterol. 2019 Apr 29. pii: S2210-7401(19)30089-0. doi: 10.1016/j.clinre.2019.03.012. [Epub ahead of print]

PMID:
31047837
4.

Porto-sinusoidal vascular disease: proposal and description of a novel entity.

De Gottardi A, Rautou PE, Schouten J, Rubbia-Brandt L, Leebeek F, Trebicka J, Murad SD, Vilgrain V, Hernandez-Gea V, Nery F, Plessier A, Berzigotti A, Bioulac-Sage P, Primignani M, Semela D, Elkrief L, Bedossa P, Valla D, Garcia-Pagan JC; VALDIG group.

Lancet Gastroenterol Hepatol. 2019 May;4(5):399-411. doi: 10.1016/S2468-1253(19)30047-0.

PMID:
30957754
5.

A 17-Beta-Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease.

Yang J, Trépo E, Nahon P, Cao Q, Moreno C, Letouzé E, Imbeaud S, Bayard Q, Gustot T, Deviere J, Bioulac-Sage P, Calderaro J, Ganne-Carrié N, Laurent A, Blanc JF, Guyot E, Sutton A, Ziol M, Zucman-Rossi J, Nault JC.

Hepatology. 2019 Jul;70(1):231-240. doi: 10.1002/hep.30623. Epub 2019 Apr 25.

PMID:
30908678
6.

Repeat surgery in HNF1alpha-inactivated adenomatosis.

Balabaud C, Laurent C, Frulio N, Marie Christine SP, Le Bail B, Possenti L, Blanc JF, Chiche L, Bioulac-Sage P.

Clin Res Hepatol Gastroenterol. 2019 Mar 19. pii: S2210-7401(18)30257-2. doi: 10.1016/j.clinre.2018.11.001. [Epub ahead of print]

PMID:
30902584
7.

Actin Depolymerization in Dedifferentiated Liver Sinusoidal Endothelial Cells Promotes Fenestrae Re-Formation.

Di Martino J, Mascalchi P, Legros P, Lacomme S, Gontier E, Bioulac-Sage P, Balabaud C, Moreau V, Saltel F.

Hepatol Commun. 2018 Dec 28;3(2):213-219. doi: 10.1002/hep4.1301. eCollection 2019 Feb.

8.

New MRI features improve subtype classification of hepatocellular adenoma.

Bise S, Frulio N, Hocquelet A, Alberti N, Blanc JF, Laurent C, Laumonier H, Balabaud C, Bioulac-Sage P, Trillaud H.

Eur Radiol. 2019 May;29(5):2436-2447. doi: 10.1007/s00330-018-5784-5. Epub 2018 Dec 6.

PMID:
30523457
9.

Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress.

Bayard Q, Meunier L, Peneau C, Renault V, Shinde J, Nault JC, Mami I, Couchy G, Amaddeo G, Tubacher E, Bacq D, Meyer V, La Bella T, Debaillon-Vesque A, Bioulac-Sage P, Seror O, Blanc JF, Calderaro J, Deleuze JF, Imbeaud S, Zucman-Rossi J, Letouzé E.

Nat Commun. 2018 Dec 7;9(1):5235. doi: 10.1038/s41467-018-07552-9.

10.

PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases.

Yang J, Trépo E, Nahon P, Cao Q, Moreno C, Letouzé E, Imbeaud S, Gustot T, Deviere J, Debette S, Amouyel P, Bioulac-Sage P, Calderaro J, Ganne-Carrié N, Laurent A, Blanc JF, Guyot E, Sutton A, Ziol M, Zucman-Rossi J, Nault JC.

Int J Cancer. 2019 Feb 1;144(3):533-544. doi: 10.1002/ijc.31910. Epub 2018 Nov 9.

PMID:
30289982
11.

OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy.

Sciarra A, Schmidt S, Pellegrinelli A, Maggioni M, Dondossola D, Pasquier J, Cigala C, Tosi D, Halkic N, Bulfamante G, Viale G, Bosari S, Balabaud C, Bioulac-Sage P, Sempoux C.

Liver Int. 2019 Jan;39(1):158-167. doi: 10.1111/liv.13964. Epub 2018 Oct 8.

PMID:
30218633
12.

Snapshot summary of diagnosis and management of hepatocellular adenoma subtypes.

Bioulac-Sage P, Sempoux C, Frulio N, Le Bail B, Blanc JF, Castain C, Laurent C, Trillaud H, Chiche L, Balabaud C.

Clin Res Hepatol Gastroenterol. 2019 Feb;43(1):12-19. doi: 10.1016/j.clinre.2018.07.007. Epub 2018 Sep 10.

PMID:
30213653
13.

A difficult case of β-catenin-mutated hepatocellular adenoma: a lesson for diagnosis.

Cappellen D, Balabaud C, Bioulac-Sage P.

Histopathology. 2019 Jan;74(2):355-357. doi: 10.1111/his.13751. Epub 2018 Dec 6. No abstract available.

PMID:
30184258
14.

Collision of hepatocellular nodules in vascular livers: A medical challenge.

Le Bail B, Chiche L, Balabaud C, Bioulac-Sage P.

Clin Res Hepatol Gastroenterol. 2018 Oct;42(5):e83-e85. doi: 10.1016/j.clinre.2017.11.001. Epub 2018 Aug 23. No abstract available.

PMID:
30145279
15.

Histology of portal vascular changes associated with idiopathic non-cirrhotic portal hypertension: nomenclature and definition.

Guido M, Alves VAF, Balabaud C, Bathal PS, Bioulac-Sage P, Colombari R, Crawford JM, Dhillon AP, Ferrell LD, Gill RM, Hytiroglou P, Nakanuma Y, Paradis V, Quaglia A, Rautou PE, Theise ND, Thung S, Tsui WMS, Sempoux C, Snover D, van Leeuwen DJ; International Liver Pathology Study Group.

Histopathology. 2019 Jan;74(2):219-226. doi: 10.1111/his.13738. Epub 2018 Oct 17. Review.

PMID:
30129657
16.

STED microscopy: A simplified method for liver sinusoidal endothelial fenestrae analysis.

Di Martino J, Mascalchi P, Legros P, Lacomme S, Gontier E, Bioulac-Sage P, Balabaud C, Moreau V, Saltel F.

Biol Cell. 2018 Jul;110(7):159-168. doi: 10.1111/boc.201800016. Epub 2018 Jun 25.

PMID:
29808906
17.

Acute-on-chronic liver failure 2018: a need for (urgent) liver biopsy?

van Leeuwen DJ, Alves V, Balabaud C, Bhathal PS, Bioulac-Sage P, Colombari R, Crawford JM, Dhillon AP, Ferrell L, Gill RM, Guido M, Hytiroglou P, Nakanuma Y, Paradis V, Rautou PE, Sempoux C, Snover DC, Theise ND, Thung SN, Tsui WMS, Quaglia A, Liver Pathology Study Group TI.

Expert Rev Gastroenterol Hepatol. 2018 Jun;12(6):565-573. doi: 10.1080/17474124.2018.1481388. Epub 2018 Jun 14. Review.

PMID:
29806950
18.

Hepatocellular nodules in vascular liver diseases.

Sempoux C, Balabaud C, Paradis V, Bioulac-Sage P.

Virchows Arch. 2018 Jul;473(1):33-44. doi: 10.1007/s00428-018-2373-6. Epub 2018 May 26. Review.

PMID:
29804132
19.

Influence of Progenitor-Derived Regeneration Markers on Hepatitis C Virus-Related Cirrhosis Outcome (ANRS CO12 CirVir Cohort).

Wendum D, Layese R, Ganne-Carrié N, Bourcier V, Merabtene F, Cagnot C, Sauce E, Barget N, Bedossa P, Terris B, Selves J, Bioulac-Sage P, Sturm N, Sattonnet C, Nahon P, Roudot-Thoraval F, Ziol M; ANRS CO12 CirVir Group.

Hepatology. 2018 Oct;68(4):1534-1548. doi: 10.1002/hep.29927.

PMID:
29637581
20.

Vascular liver lesions: contemporary views on long-recognized entities.

Sempoux C, Bioulac-Sage P.

Virchows Arch. 2018 Jul;473(1):1-2. doi: 10.1007/s00428-018-2328-y. Epub 2018 Mar 14. No abstract available.

PMID:
29536168
21.

Unexpected discovery of small HNF1α-inactivated hepatocellular adenoma in pathological specimens from patients resected for liver tumours.

Balabaud C, Laurent C, Le Bail B, Castain C, Possenti L, Frulio N, Chiche L, Blanc JF, Bioulac-Sage P.

Liver Int. 2018 Jul;38(7):1273-1279. doi: 10.1111/liv.13667. Epub 2018 Jan 17.

PMID:
29265678
22.

Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis.

Letouzé E, Shinde J, Renault V, Couchy G, Blanc JF, Tubacher E, Bayard Q, Bacq D, Meyer V, Semhoun J, Bioulac-Sage P, Prévôt S, Azoulay D, Paradis V, Imbeaud S, Deleuze JF, Zucman-Rossi J.

Nat Commun. 2017 Nov 3;8(1):1315. doi: 10.1038/s41467-017-01358-x.

23.

Reply.

Rebouissou S, Bioulac-Sage P, Nault JC, Calderaro J, Zucman-Rossi J.

Hepatology. 2017 Dec;66(6):2093-2094. doi: 10.1002/hep.29563. Epub 2017 Nov 6. No abstract available.

PMID:
28961324
24.

Hepatitis B Virus Pregenomic RNA in Hepatocellular Carcinoma: A Nosological and Prognostic Determinant.

Halgand B, Desterke C, Rivière L, Fallot G, Sebagh M, Calderaro J, Bioulac-Sage P, Neuveut C, Buendia MA, Samuel D, Féray C.

Hepatology. 2018 Jan;67(1):86-96. doi: 10.1002/hep.29463.

PMID:
28802063
25.

Argininosuccinate synthase 1 (ASS1): A marker of unclassified hepatocellular adenoma and high bleeding risk.

Henriet E, Abou Hammoud A, Dupuy JW, Dartigues B, Ezzoukry Z, Dugot-Senant N, Leste-Lasserre T, Pallares-Lupon N, Nikolski M, Le Bail B, Blanc JF, Balabaud C, Bioulac-Sage P, Raymond AA, Saltel F.

Hepatology. 2017 Dec;66(6):2016-2028. doi: 10.1002/hep.29336. Epub 2017 Oct 30.

PMID:
28646562
26.

Focal β-catenin mutation identified on formalin-fixed and paraffin-embedded inflammatory hepatocellular adenomas.

Saldarriaga J, Bisig B, Couchy G, Castain C, Zucman-Rossi J, Balabaud C, Sempoux C, Bioulac-Sage P.

Histopathology. 2017 Dec;71(6):989-993. doi: 10.1111/his.13283. Epub 2017 Oct 6.

PMID:
28618047
27.

Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.

Calderaro J, Couchy G, Imbeaud S, Amaddeo G, Letouzé E, Blanc JF, Laurent C, Hajji Y, Azoulay D, Bioulac-Sage P, Nault JC, Zucman-Rossi J.

J Hepatol. 2017 Oct;67(4):727-738. doi: 10.1016/j.jhep.2017.05.014. Epub 2017 May 19.

PMID:
28532995
28.

Hepatocellular Adenomas: Morphology and Genomics.

Bioulac-Sage P, Sempoux C, Balabaud C.

Gastroenterol Clin North Am. 2017 Jun;46(2):253-272. doi: 10.1016/j.gtc.2017.01.003. Review.

PMID:
28506364
29.

Proliferation Markers Are Associated with MET Expression in Hepatocellular Carcinoma and Predict Tivantinib Sensitivity In Vitro.

Rebouissou S, La Bella T, Rekik S, Imbeaud S, Calatayud AL, Rohr-Udilova N, Martin Y, Couchy G, Bioulac-Sage P, Grasl-Kraupp B, de Koning L, Ganne-Carrié N, Nault JC, Ziol M, Zucman-Rossi J.

Clin Cancer Res. 2017 Aug 1;23(15):4364-4375. doi: 10.1158/1078-0432.CCR-16-3118. Epub 2017 Feb 28.

30.

Hepatocellular adenoma: Classification, variants and clinical relevance.

Bioulac-Sage P, Sempoux C, Balabaud C.

Semin Diagn Pathol. 2017 Mar;34(2):112-125. doi: 10.1053/j.semdp.2016.12.007. Epub 2016 Dec 20. Review.

PMID:
28131467
31.

CYP1A2 is a predictor of HCC recurrence in HCV-related chronic liver disease: A retrospective multicentric validation study.

Sciarra A, Pintea B, Nahm JH, Donadon M, Morenghi E, Maggioni M, Blanc JF, Torzilli G, Yeh M, Bioulac-Sage P, Park YN, Roncalli M, Di Tommaso L.

Dig Liver Dis. 2017 Apr;49(4):434-439. doi: 10.1016/j.dld.2016.12.002. Epub 2016 Dec 16.

PMID:
28040498
32.

Germline and somatic DICER1 mutations in familial and sporadic liver tumors.

Caruso S, Calderaro J, Letouzé E, Nault JC, Couchy G, Boulai A, Luciani A, Zafrani ES, Bioulac-Sage P, Seror O, Imbeaud S, Zucman-Rossi J.

J Hepatol. 2017 Apr;66(4):734-742. doi: 10.1016/j.jhep.2016.12.010. Epub 2016 Dec 22.

PMID:
28012864
33.

Malignant transformation of a β-catenin inflammatory adenoma due to an S45 β-catenin-activating mutation present 12 years before.

Sempoux C, Bisig B, Couchy G, Balabaud C, Zucman-Rossi J, Bioulac-Sage P.

Hum Pathol. 2017 Apr;62:122-125. doi: 10.1016/j.humpath.2016.10.004. Epub 2016 Oct 28.

PMID:
27984126
34.

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.

Nault JC, Couchy G, Balabaud C, Morcrette G, Caruso S, Blanc JF, Bacq Y, Calderaro J, Paradis V, Ramos J, Scoazec JY, Gnemmi V, Sturm N, Guettier C, Fabre M, Savier E, Chiche L, Labrune P, Selves J, Wendum D, Pilati C, Laurent A, De Muret A, Le Bail B, Rebouissou S, Imbeaud S; GENTHEP Investigators, Bioulac-Sage P, Letouzé E, Zucman-Rossi J.

Gastroenterology. 2017 Mar;152(4):880-894.e6. doi: 10.1053/j.gastro.2016.11.042. Epub 2016 Dec 7.

35.

TGF-β1 promotes linear invadosome formation in hepatocellular carcinoma cells, through DDR1 up-regulation and collagen I cross-linking.

Ezzoukhry Z, Henriet E, Piquet L, Boyé K, Bioulac-Sage P, Balabaud C, Couchy G, Zucman-Rossi J, Moreau V, Saltel F.

Eur J Cell Biol. 2016 Nov;95(11):503-512. doi: 10.1016/j.ejcb.2016.09.003. Epub 2016 Oct 4.

PMID:
27720259
36.

Genotype-phenotype correlation of CTNNB1 mutations reveals different ß-catenin activity associated with liver tumor progression.

Rebouissou S, Franconi A, Calderaro J, Letouzé E, Imbeaud S, Pilati C, Nault JC, Couchy G, Laurent A, Balabaud C, Bioulac-Sage P, Zucman-Rossi J.

Hepatology. 2016 Dec;64(6):2047-2061. doi: 10.1002/hep.28638. Epub 2016 Jun 11.

PMID:
27177928
37.

Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV.

Nault JC, Mami I, La Bella T, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J.

Mol Ther. 2016 Apr;24(4):660-1. doi: 10.1038/mt.2016.47. No abstract available.

38.

AAV2 and Hepatocellular Carcinoma.

Nault JC, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J.

Hum Gene Ther. 2016 Mar;27(3):211-3. doi: 10.1089/hum.2016.002. No abstract available.

PMID:
26935016
39.

Liver transplantation for adenomatosis: European experience.

Chiche L, David A, Adam R, Oliverius MM, Klempnauer J, Vibert E, Colledan M, Lerut J, Mazzafero VV, Di-Sandro S, Laurent C, Scuderi V, Suc B, Troisi R, Bachelier P, Dumortier J, Gugenheim J, Mabrut JY, Gonzalez-Pinto I, Pruvot FR, Le-Treut YP, Navarro F, Ortiz-de-Urbina J, Salamé E, Spada M, Bioulac-Sage P.

Liver Transpl. 2016 Apr;22(4):516-26. doi: 10.1002/lt.24417.

40.

Role of aetiology in the progression, regression, and parenchymal remodelling of liver disease: implications for liver biopsy interpretation.

Quaglia A, Alves VA, Balabaud C, Bhathal PS, Bioulac-Sage P, Crawford JM, Dhillon AP, Ferrell L, Guido M, Hytiroglou P, Nakanuma Y, Paradis V, Snover DC, Theise ND, Thung SN, Tsui WM, van Leeuwen DJ; International Liver Pathology Study Group.

Histopathology. 2016 Jun;68(7):953-67. doi: 10.1111/his.12957. Epub 2016 Apr 28. Review.

PMID:
26918878
41.

Inflammatory hepatocellular adenomas developed in the setting of chronic liver disease and cirrhosis.

Calderaro J, Nault JC, Balabaud C, Couchy G, Saint-Paul MC, Azoulay D, Mehdaoui D, Luciani A, Zafrani ES, Bioulac-Sage P, Zucman-Rossi J.

Mod Pathol. 2016 Jan;29(1):43-50. doi: 10.1038/modpathol.2015.119. Epub 2015 Oct 30.

42.

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas.

Nault JC, Datta S, Imbeaud S, Franconi A, Mallet M, Couchy G, Letouzé E, Pilati C, Verret B, Blanc JF, Balabaud C, Calderaro J, Laurent A, Letexier M, Bioulac-Sage P, Calvo F, Zucman-Rossi J.

Nat Genet. 2015 Oct;47(10):1187-93. doi: 10.1038/ng.3389. Epub 2015 Aug 24.

PMID:
26301494
43.

Simultaneous occurrence of focal nodular hyperplasia and HNF1A-inactivated hepatocellular adenoma: a collision tumor simulating a composite FNH-HCA.

Shih A, Lauwers GY, Balabaud C, Bioulac-Sage P, Misdraji J.

Am J Surg Pathol. 2015 Sep;39(9):1296-300. doi: 10.1097/PAS.0000000000000477.

PMID:
26274031
44.

Liver-infiltrating CD8(+) lymphocytes as prognostic factor for tumour recurrence in hepatitis C virus-related hepatocellular carcinoma.

Ramzan M, Sturm N, Decaens T, Bioulac-Sage P, Bancel B, Merle P, Tran Van Nhieu J, Slama R, Letoublon C, Zarski JP, Jouvin-Marche E, Marche PN, Leroy V.

Liver Int. 2016 Mar;36(3):434-44. doi: 10.1111/liv.12927. Epub 2015 Sep 29.

PMID:
26215124
45.

Hepatocellular nodules expressing markers of hepatocellular adenomas in Budd-Chiari syndrome and other rare hepatic vascular disorders.

Sempoux C, Paradis V, Komuta M, Wee A, Calderaro J, Balabaud C, Quaglia A, Bioulac-Sage P.

J Hepatol. 2015 Nov;63(5):1173-80. doi: 10.1016/j.jhep.2015.06.017. Epub 2015 Jun 25.

PMID:
26119687
46.

Hepatocellular adenoma management: advances but still a long way to go.

Blanc JF, Frulio N, Chiche L, Bioulac-Sage P, Balabaud C.

Hepat Oncol. 2015 Apr;2(2):171-180. doi: 10.2217/hep.14.41. Epub 2015 May 15. Review.

47.

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.

Schulze K, Imbeaud S, Letouzé E, Alexandrov LB, Calderaro J, Rebouissou S, Couchy G, Meiller C, Shinde J, Soysouvanh F, Calatayud AL, Pinyol R, Pelletier L, Balabaud C, Laurent A, Blanc JF, Mazzaferro V, Calvo F, Villanueva A, Nault JC, Bioulac-Sage P, Stratton MR, Llovet JM, Zucman-Rossi J.

Nat Genet. 2015 May;47(5):505-511. doi: 10.1038/ng.3252. Epub 2015 Mar 30.

48.

Noninvasive assessment of macrovesicular liver steatosis in cadaveric donors based on computed tomography liver-to-spleen attenuation ratio.

Rogier J, Roullet S, Cornélis F, Biais M, Quinart A, Revel P, Bioulac-Sage P, Le Bail B.

Liver Transpl. 2015 May;21(5):690-5. doi: 10.1002/lt.24105.

49.

BRAF V600E mutational status in bile duct adenomas and hamartomas.

Pujals A, Bioulac-Sage P, Castain C, Charpy C, Zafrani ES, Calderaro J.

Histopathology. 2015 Oct;67(4):562-7. doi: 10.1111/his.12674. Epub 2015 Mar 31.

PMID:
25704541
50.

Well-differentiated hepatocellular neoplasm of uncertain malignant potential.

Balabaud C, Bioulac-Sage P, Ferrell L, Kakar S, Paradis V, Quaglia A, Sempoux C, Thung S, Zucman-Rossi J.

Hum Pathol. 2015 Apr;46(4):634-5. doi: 10.1016/j.humpath.2014.10.029. Epub 2014 Dec 31. No abstract available.

PMID:
25661243

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