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Items: 1 to 50 of 156

1.

A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT.

Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Everingham K, Kocman D, Lourtie J, Drake S, Girling A, Lilford R, Rivett K, Wells D, Mahajan R, Holt P, Yang F, Walker S, Richardson G, Kerry S, Anderson I, Murray D, Cromwell D, Phull M, Grocott MPW, Bion J, Pearse RM; the EPOCH trial group .

Southampton (UK): NIHR Journals Library; 2019 Sep.

2.

Patient experience and reflective learning (PEARL): a mixed methods protocol for staff insight development in acute and intensive care medicine in the UK.

Brookes O, Brown C, Tarrant C, Archer J, Buckley D, Buckley LM, Clement I, Evison F, Gao Smith F, Gibbins C, Hayton E, Jones J, Lilford R, Mullhi R, Packer G, Perkins G, Shelton J, Snelson C, Sullivan P, Vlaev I, Wolstenholme D, Wright SE, Bion J; On-behalf-of the PEARL Collaboration.

BMJ Open. 2019 Jul 24;9(7):e030679. doi: 10.1136/bmjopen-2019-030679.

3.

Cost Effectiveness of Advanced Pharmacy Services Provided in the Community and Primary Care Settings: A Systematic Review.

Dawoud DM, Haines A, Wonderling D, Ashe J, Hill J, Varia M, Dyer P, Bion J.

Pharmacoeconomics. 2019 Oct;37(10):1241-1260. doi: 10.1007/s40273-019-00814-4. Review.

PMID:
31179514
4.

Magnitude and modifiers of the weekend effect in hospital admissions: a systematic review and meta-analysis.

Chen YF, Armoiry X, Higenbottam C, Cowley N, Basra R, Watson SI, Tarrant C, Boyal A, Sutton E, Wu CW, Aldridge CP, Gosling A, Lilford R, Bion J.

BMJ Open. 2019 Jun 4;9(6):e025764. doi: 10.1136/bmjopen-2018-025764. Erratum in: BMJ Open. 2019 Jun 27;9(6):e025764corr1.

5.

Methodological challenges in European ethics approvals for a genetic epidemiology study in critically ill patients: the GenOSept experience.

Tridente A, Holloway PAH, Hutton P, Gordon AC, Mills GH, Clarke GM, Chiche JD, Stuber F, Garrard C, Hinds C, Bion J; GenOSept National Coordinators, European Society of Intensive Care Medicine.

BMC Med Ethics. 2019 May 7;20(1):30. doi: 10.1186/s12910-019-0370-1.

6.

Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial.

Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Rivett K, Wells D, Richardson G, Kerry S, Bion J, Pearse RM; Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial group.

Lancet. 2019 Jun 1;393(10187):2213-2221. doi: 10.1016/S0140-6736(18)32521-2. Epub 2019 Apr 25.

7.

Observational vs randomized: David vs Goliath for thromboprophylaxis in critically ill patients?

Helms J, Bion J, De Jong A.

Intensive Care Med. 2019 Feb;45(2):272-274. doi: 10.1007/s00134-019-05541-0. Epub 2019 Jan 28. No abstract available.

PMID:
30688997
8.

The weekend effect in status epilepticus: a national cohort study.

Goulden R, Whitehouse T, Murphy N, Hayton T, Khan Z, Shyamsundar M, Gao-Smith F, Snelson C, Bion J, Veenith T.

Anaesthesia. 2019 Apr;74(4):468-472. doi: 10.1111/anae.14571. Epub 2019 Jan 3.

PMID:
30604863
9.

Quality and safety of in-hospital care for acute medical patients at weekends: a qualitative study.

Sutton E, Bion J, Aldridge C, Boyal A, Willars J, Tarrant C.

BMC Health Serv Res. 2018 Dec 29;18(1):1015. doi: 10.1186/s12913-018-3833-z.

10.

Effectiveness and cost effectiveness of pharmacist input at the ward level: a systematic review and meta-analysis.

Dawoud DM, Smyth M, Ashe J, Strong T, Wonderling D, Hill J, Varia M, Dyer P, Bion J.

Res Social Adm Pharm. 2019 Oct;15(10):1212-1222. doi: 10.1016/j.sapharm.2018.10.006. Epub 2018 Oct 19.

PMID:
30389320
11.

Sicker patients account for the weekend mortality effect among adult emergency admissions to a large hospital trust.

Sun J, Girling AJ, Aldridge C, Evison F, Beet C, Boyal A, Rudge G, Lilford RJ, Bion J.

BMJ Qual Saf. 2019 Mar;28(3):223-230. doi: 10.1136/bmjqs-2018-008219. Epub 2018 Oct 9.

12.

Correction to: White paper: statement on conflicts of interest.

Bion J, Antonelli M, Blanch L, Curtis JR, Druml C, Du B, Machado FR, Gomersall C, Hartog C, Levy M, Myburgh J, Rubenfeld G, Sprung C.

Intensive Care Med. 2018 Nov;44(11):2021. doi: 10.1007/s00134-018-5373-8.

PMID:
30225624
13.

White paper: statement on conflicts of interest.

Bion J, Antonelli M, Blanch L, Curtis JR, Druml C, Du B, Machado FR, Gomersall C, Hartog C, Levy M, Myburgh J, Rubenfeld G, Sprung C.

Intensive Care Med. 2018 Oct;44(10):1657-1668. doi: 10.1007/s00134-018-5349-8. Epub 2018 Sep 6. Erratum in: Intensive Care Med. 2018 Sep 17;:.

PMID:
30191294
14.

Intensive care medicine in 2050: preventing harm.

Beet C, Benoit D, Bion J.

Intensive Care Med. 2019 Apr;45(4):505-507. doi: 10.1007/s00134-018-5353-z. Epub 2018 Sep 3. No abstract available.

PMID:
30178134
15.

Association Between Hospital Volume and Mortality in Status Epilepticus: A National Cohort Study.

Goulden R, Whitehouse T, Murphy N, Hayton T, Khan Z, Snelson C, Bion J, Veenith T.

Crit Care Med. 2018 Dec;46(12):1969-1976. doi: 10.1097/CCM.0000000000003392.

PMID:
30134302
16.

Should hydroxyethyl starch be banned? - Authors' reply.

Roberts I, Shakur H, Bellomo R, Bion J, Finfer S, Hunt B, Myburgh J, Perner A, Reinhart K.

Lancet. 2018 Jul 14;392(10142):119. doi: 10.1016/S0140-6736(18)31179-6. No abstract available.

PMID:
30017130
17.

Antipathy against SDD is justified: No.

Silvestri L, van Saene HKF, Bion J.

Intensive Care Med. 2018 Jul;44(7):1169-1173. doi: 10.1007/s00134-018-5144-6. Epub 2018 Jun 7. No abstract available.

PMID:
29881988
18.

Protocol for the health economic evaluation of increasing the weekend specialist to patient ratio in hospitals in England.

Watson SI, Chen YF, Bion JF, Aldridge CP, Girling A, Lilford RJ; HiSLAC Collaboration.

BMJ Open. 2018 Feb 23;8(2):e015561. doi: 10.1136/bmjopen-2016-015561.

19.

Hydroxyethyl starch solutions and patient harm.

Roberts I, Shakur H, Bellomo R, Bion J, Finfer S, Hunt B, Myburgh J, Perner A, Reinhart K.

Lancet. 2018 Feb 24;391(10122):736. doi: 10.1016/S0140-6736(18)30255-1. Epub 2018 Feb 12. No abstract available.

PMID:
29449012
20.

Two-epoch cross-sectional case record review protocol comparing quality of care of hospital emergency admissions at weekends versus weekdays.

Bion J, Aldridge CP, Girling A, Rudge G, Beet C, Evans T, Temple RM, Roseveare C, Clancy M, Boyal A, Tarrant C, Sutton E, Sun J, Rees P, Mannion R, Chen YF, Watson SI, Lilford R; HiSLAC collaboration.

BMJ Open. 2017 Dec 22;7(12):e018747. doi: 10.1136/bmjopen-2017-018747.

21.

A qualitative study of speaking out about patient safety concerns in intensive care units.

Tarrant C, Leslie M, Bion J, Dixon-Woods M.

Soc Sci Med. 2017 Nov;193:8-15. doi: 10.1016/j.socscimed.2017.09.036. Epub 2017 Sep 22.

22.

Cytomegalovirus in Patients in the Intensive Care Unit-Reply.

Cowley NJ, Moss P, Bion JF.

JAMA Intern Med. 2017 Oct 1;177(10):1543. doi: 10.1001/jamainternmed.2017.4401. No abstract available.

PMID:
28973283
23.

Derivation and validation of a prognostic model for postoperative risk stratification of critically ill patients with faecal peritonitis.

Tridente A, Bion J, Mills GH, Gordon AC, Clarke GM, Walden A, Hutton P, Holloway PAH, Chiche JD, Stuber F, Garrard C, Hinds C; GenOSept and GAinS Investigators.

Ann Intensive Care. 2017 Sep 12;7(1):96. doi: 10.1186/s13613-017-0314-1.

24.

Surviving Sepsis Campaign Guidelines 2016: omission of selective decontamination of the digestive tract deprives patients of a level 2B therapy.

Silvestri L, van Saene HK, Rommes JH, Petros AJ, de la Cal MA, Bion JF.

Minerva Anestesiol. 2017 Nov;83(11):1214-1215. doi: 10.23736/S0375-9393.17.12105-X. Epub 2017 Jun 12. No abstract available.

25.

Safety and Efficacy of Antiviral Therapy for Prevention of Cytomegalovirus Reactivation in Immunocompetent Critically Ill Patients: A Randomized Clinical Trial.

Cowley NJ, Owen A, Shiels SC, Millar J, Woolley R, Ives N, Osman H, Moss P, Bion JF.

JAMA Intern Med. 2017 Jun 1;177(6):774-783. doi: 10.1001/jamainternmed.2017.0895.

26.

The Association Between Visiting Intensivists and ICU Outcomes.

Whitehouse T, Hodson J, Pemberton P, Veenith T, Snelson C, Bion J, Rubenfeld GD.

Crit Care Med. 2017 Jun;45(6):949-955. doi: 10.1097/CCM.0000000000002373.

PMID:
28398923
27.

The 'weekend effect' in acute medicine: a protocol for a team-based ethnography of weekend care for medical patients in acute hospital settings.

Tarrant C, Sutton E, Angell E, Aldridge CP, Boyal A, Bion J; HiSLAC study.

BMJ Open. 2017 Apr 5;7(4):e016755. doi: 10.1136/bmjopen-2017-016755.

28.

A complex endeavour: an ethnographic study of the implementation of the Sepsis Six clinical care bundle.

Tarrant C, O'Donnell B, Martin G, Bion J, Hunter A, Rooney KD.

Implement Sci. 2016 Nov 16;11(1):149.

29.

The magnitude and mechanisms of the weekend effect in hospital admissions: A protocol for a mixed methods review incorporating a systematic review and framework synthesis.

Chen YF, Boyal A, Sutton E, Armoiry X, Watson S, Bion J, Tarrant C; HiSLAC Collaborative.

Syst Rev. 2016 May 21;5:84. doi: 10.1186/s13643-016-0260-2.

30.

Weekend specialist intensity and admission mortality in acute hospital trusts in England: a cross-sectional study.

Aldridge C, Bion J, Boyal A, Chen YF, Clancy M, Evans T, Girling A, Lord J, Mannion R, Rees P, Roseveare C, Rudge G, Sun J, Tarrant C, Temple M, Watson S, Lilford R; HiSLAC Collaborative.

Lancet. 2016 Jul 9;388(10040):178-86. doi: 10.1016/S0140-6736(16)30442-1. Epub 2016 May 10.

31.

Conditions for making trial data available to other investigators.

Bion JF.

BMJ. 2016 Mar 21;352:i1573. doi: 10.1136/bmj.i1573. No abstract available.

PMID:
27001258
32.

The ethics of migration and critical illness.

Bion J, Azoulay E.

Intensive Care Med. 2016 Feb;42(2):256-7. doi: 10.1007/s00134-015-4146-x. Epub 2015 Nov 24. No abstract available.

PMID:
26602783
33.

Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock.

Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Tan JC, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM.

Health Technol Assess. 2015 Nov;19(97):i-xxv, 1-150. doi: 10.3310/hta19970.

34.

Primary Speciality Intensive Care: Pedagogy, Professionalism, and Patients.

Bion J.

Crit Care Med. 2015 Sep;43(9):2020-1. doi: 10.1097/CCM.0000000000001215. No abstract available.

PMID:
26274706
35.

Virtual restorative environment therapy as an adjunct to pain control during burn dressing changes: study protocol for a randomised controlled trial.

Small C, Stone R, Pilsbury J, Bowden M, Bion J.

Trials. 2015 Aug 5;16:329. doi: 10.1186/s13063-015-0878-8.

36.

Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort.

Mills TC, Chapman S, Hutton P, Gordon AC, Bion J, Chiche JD, Holloway PA, Stüber F, Garrard CS, Hinds CJ, Hill AV, Rautanen A; ESICM/ECCRN GenOSept Investigators.

Clin Infect Dis. 2015 Sep 1;61(5):695-703. doi: 10.1093/cid/civ378. Epub 2015 May 12.

37.

Association between trends in clinical variables and outcome in intensive care patients with faecal peritonitis: analysis of the GenOSept cohort.

Tridente A, Clarke GM, Walden A, Gordon AC, Hutton P, Chiche JD, Holloway PA, Mills GH, Bion J, Stüber F, Garrard C, Hinds C; GenOSept Investigators.

Crit Care. 2015 May 5;19:210. doi: 10.1186/s13054-015-0931-8.

38.

Balancing cure with comfort: palliative care in critical care.

Bion J, Coombs M.

Palliat Med. 2015 Apr;29(4):288-90. doi: 10.1177/0269216315574648. No abstract available.

PMID:
25800271
39.

Trial of early, goal-directed resuscitation for septic shock.

Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM; ProMISe Trial Investigators.

N Engl J Med. 2015 Apr 2;372(14):1301-11. doi: 10.1056/NEJMoa1500896. Epub 2015 Mar 17.

40.

Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study.

Rautanen A, Mills TC, Gordon AC, Hutton P, Steffens M, Nuamah R, Chiche JD, Parks T, Chapman SJ, Davenport EE, Elliott KS, Bion J, Lichtner P, Meitinger T, Wienker TF, Caulfield MJ, Mein C, Bloos F, Bobek I, Cotogni P, Sramek V, Sarapuu S, Kobilay M, Ranieri VM, Rello J, Sirgo G, Weiss YG, Russwurm S, Schneider EM, Reinhart K, Holloway PA, Knight JC, Garrard CS, Russell JA, Walley KR, Stüber F, Hill AV, Hinds CJ; ESICM/ECCRN GenOSept Investigators.

Lancet Respir Med. 2015 Jan;3(1):53-60. doi: 10.1016/S2213-2600(14)70290-5. Epub 2014 Dec 18.

41.

Enhancing rehabilitation of mechanically ventilated patients in the intensive care unit: a quality improvement project.

McWilliams D, Weblin J, Atkins G, Bion J, Williams J, Elliott C, Whitehouse T, Snelson C.

J Crit Care. 2015 Feb;30(1):13-8. doi: 10.1016/j.jcrc.2014.09.018. Epub 2014 Oct 2.

42.

Open Letter to the Executive Director of the European Medicines Agency concerning the licensing of hydroxyethyl starch solutions for fluid resuscitation.

Bellomo R, Bion J, Finfer S, Myburgh J, Perner A, Reinhart K.

Acta Anaesthesiol Scand. 2014 Mar;58(3):365-70. No abstract available.

PMID:
25237699
43.

Night thoughts.

Guidet B, Bion J.

Intensive Care Med. 2014 Oct;40(10):1586-8. doi: 10.1007/s00134-014-3467-5. Epub 2014 Sep 3. No abstract available.

PMID:
25183573
44.

Keystone, matching Michigan, and bacteremia zero.

Bion JF, Dixon-Woods M.

Crit Care Med. 2014 May;42(5):e383-4. doi: 10.1097/CCM.0000000000000190. No abstract available.

PMID:
24736363
45.

Open letter to the Executive Director of the European Medicines Agency concerning the licensing of hydroxyethyl starch solutions for fluid resuscitation.

Bellomo R, Bion J, Finfer S, Myburgh J, Perner A, Reinhart K; all co-signatories.

Br J Anaesth. 2014 Mar;112(3):595-600. doi: 10.1093/bja/aeu025. No abstract available.

46.

Gut instinct.

Bion J.

Crit Care. 2013 Dec 19;17(6):1025. doi: 10.1186/cc13165.

47.

Hydroxyethyl starch: putting patient safety first.

Bion J, Bellomo R, Myburgh J, Perner A, Reinhart K, Finfer S.

Intensive Care Med. 2014 Feb;40(2):256-9. doi: 10.1007/s00134-013-3167-6. Epub 2013 Dec 19. No abstract available.

PMID:
24352482
48.

Models for intensive care training. A European perspective.

Bion J, Rothen HU.

Am J Respir Crit Care Med. 2014 Feb 1;189(3):256-62. doi: 10.1164/rccm.201311-2058CP.

PMID:
24351076
49.

Patients with faecal peritonitis admitted to European intensive care units: an epidemiological survey of the GenOSept cohort.

Tridente A, Clarke GM, Walden A, McKechnie S, Hutton P, Mills GH, Gordon AC, Holloway PA, Chiche JD, Bion J, Stuber F, Garrard C, Hinds CJ; GenOSept Investigators.

Intensive Care Med. 2014 Feb;40(2):202-10. doi: 10.1007/s00134-013-3158-7. Epub 2013 Dec 4.

PMID:
24306080
50.

[Interpretation of arterial blood gas analyses].

Cowley NJ, Owen A, Bion JF.

Praxis (Bern 1994). 2013 Jul 24;102(15):937-42. doi: 10.1024/1661-8157/a001357. German. No abstract available.

PMID:
23876692

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