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Items: 18


Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons.

Döhner K, Ramos-Nascimento A, Bialy D, Anderson F, Hickford-Martinez A, Rother F, Koithan T, Rudolph K, Buch A, Prank U, Binz A, Hügel S, Lebbink RJ, Hoeben RC, Hartmann E, Bader M, Bauerfeind R, Sodeik B.

PLoS Pathog. 2018 Jan 5;14(1):e1006823. doi: 10.1371/journal.ppat.1006823. eCollection 2018 Jan.


Inner tegument proteins of Herpes Simplex Virus are sufficient for intracellular capsid motility in neurons but not for axonal targeting.

Buch A, Müller O, Ivanova L, Döhner K, Bialy D, Bosse JB, Pohlmann A, Binz A, Hegemann M, Nagel CH, Koltzenburg M, Viejo-Borbolla A, Rosenhahn B, Bauerfeind R, Sodeik B.

PLoS Pathog. 2017 Dec 28;13(12):e1006813. doi: 10.1371/journal.ppat.1006813. eCollection 2017 Dec.


The M25 gene products are critical for the cytopathic effect of mouse cytomegalovirus.

Kutle I, Sengstake S, Templin C, Glaß M, Kubsch T, Keyser KA, Binz A, Bauerfeind R, Sodeik B, Čičin-Šain L, Dezeljin M, Messerle M.

Sci Rep. 2017 Nov 14;7(1):15588. doi: 10.1038/s41598-017-15783-x.


Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration.

González-Motos V, Jürgens C, Ritter B, Kropp KA, Durán V, Larsen O, Binz A, Ouwendijk WJD, Lenac Rovis T, Jonjic S, Verjans GMGM, Sodeik B, Krey T, Bauerfeind R, Schulz TF, Kaufer BB, Kalinke U, Proudfoot AEI, Rosenkilde MM, Viejo-Borbolla A.

PLoS Pathog. 2017 May 25;13(5):e1006346. doi: 10.1371/journal.ppat.1006346. eCollection 2017 May.


Cell-intrinsic, Bmal1-dependent Circadian Regulation of Temozolomide Sensitivity in Glioblastoma.

Slat EA, Sponagel J, Marpegan L, Simon T, Kfoury N, Kim A, Binz A, Herzog ED, Rubin JB.

J Biol Rhythms. 2017 Apr;32(2):121-129. doi: 10.1177/0748730417696788. Epub 2017 Mar 16.


The Essential Human Cytomegalovirus Proteins pUL77 and pUL93 Are Structural Components Necessary for Viral Genome Encapsidation.

Borst EM, Bauerfeind R, Binz A, Stephan TM, Neuber S, Wagner K, Steinbrück L, Sodeik B, Lenac Roviš T, Jonjić S, Messerle M.

J Virol. 2016 Jun 10;90(13):5860-5875. doi: 10.1128/JVI.00384-16. Print 2016 Jul 1.


Conserved Tryptophan Motifs in the Large Tegument Protein pUL36 Are Required for Efficient Secondary Envelopment of Herpes Simplex Virus Capsids.

Ivanova L, Buch A, Döhner K, Pohlmann A, Binz A, Prank U, Sandbaumhüter M, Bauerfeind R, Sodeik B.

J Virol. 2016 May 12;90(11):5368-5383. doi: 10.1128/JVI.03167-15. Print 2016 Jun 1.


The Herpes Simplex Virus Protein pUL31 Escorts Nucleocapsids to Sites of Nuclear Egress, a Process Coordinated by Its N-Terminal Domain.

Funk C, Ott M, Raschbichler V, Nagel CH, Binz A, Sodeik B, Bauerfeind R, Bailer SM.

PLoS Pathog. 2015 Jun 17;11(6):e1004957. doi: 10.1371/journal.ppat.1004957. eCollection 2015 Jun.


The interaction of the HSV-1 tegument proteins pUL36 and pUL37 is essential for secondary envelopment during viral egress.

Kelly BJ, Bauerfeind R, Binz A, Sodeik B, Laimbacher AS, Fraefel C, Diefenbach RJ.

Virology. 2014 Apr;454-455:67-77. doi: 10.1016/j.virol.2014.02.003. Epub 2014 Feb 22.


Cytosolic herpes simplex virus capsids not only require binding inner tegument protein pUL36 but also pUL37 for active transport prior to secondary envelopment.

Sandbaumhüter M, Döhner K, Schipke J, Binz A, Pohlmann A, Sodeik B, Bauerfeind R.

Cell Microbiol. 2013 Feb;15(2):248-69. doi: 10.1111/cmi.12075. Epub 2012 Dec 20.


The human cytomegalovirus UL51 protein is essential for viral genome cleavage-packaging and interacts with the terminase subunits pUL56 and pUL89.

Borst EM, Kleine-Albers J, Gabaev I, Babic M, Wagner K, Binz A, Degenhardt I, Kalesse M, Jonjic S, Bauerfeind R, Messerle M.

J Virol. 2013 Feb;87(3):1720-32. doi: 10.1128/JVI.01955-12. Epub 2012 Nov 21.


Improper tagging of the non-essential small capsid protein VP26 impairs nuclear capsid egress of herpes simplex virus.

Nagel CH, Döhner K, Binz A, Bauerfeind R, Sodeik B.

PLoS One. 2012;7(8):e44177. doi: 10.1371/journal.pone.0044177. Epub 2012 Aug 31.


Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation.

Stankov MV, Panayotova-Dimitrova D, Leverkus M, Vondran FW, Bauerfeind R, Binz A, Behrens GM.

AIDS. 2012 Oct 23;26(16):1995-2006. doi: 10.1097/QAD.0b013e32835804f9.


The C terminus of the large tegument protein pUL36 contains multiple capsid binding sites that function differently during assembly and cell entry of herpes simplex virus.

Schipke J, Pohlmann A, Diestel R, Binz A, Rudolph K, Nagel CH, Bauerfeind R, Sodeik B.

J Virol. 2012 Apr;86(7):3682-700. doi: 10.1128/JVI.06432-11. Epub 2012 Jan 18.


Uncoupling uncoating of herpes simplex virus genomes from their nuclear import and gene expression.

Rode K, Döhner K, Binz A, Glass M, Strive T, Bauerfeind R, Sodeik B.

J Virol. 2011 May;85(9):4271-83. doi: 10.1128/JVI.02067-10. Epub 2011 Feb 23.


The essential human cytomegalovirus gene UL52 is required for cleavage-packaging of the viral genome.

Borst EM, Wagner K, Binz A, Sodeik B, Messerle M.

J Virol. 2008 Mar;82(5):2065-78. Epub 2007 Dec 12.


Strategic mutations in the class I major histocompatibility complex HLA-A2 independently affect both peptide binding and T cell receptor recognition.

Baxter TK, Gagnon SJ, Davis-Harrison RL, Beck JC, Binz AK, Turner RV, Biddison WE, Baker BM.

J Biol Chem. 2004 Jul 9;279(28):29175-84. Epub 2004 May 6.


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