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Items: 13

1.

Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors.

Walker AL, Denis A, Bingham RP, Bouillot A, Edgar EV, Ferrie A, Holmes DS, Laroze A, Liddle J, Fouchet MH, Moquette A, Nassau P, Pearce AC, Polyakova O, Smith KJ, Thomas P, Thorpe JH, Trottet L, Wang Y, Hovnanian A.

Bioorg Med Chem Lett. 2019 Oct 15;29(20):126675. doi: 10.1016/j.bmcl.2019.126675. Epub 2019 Sep 7.

PMID:
31521475
2.

Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome.

Walker AL, Bingham RP, Edgar EV, Ferrie A, Holmes DS, Liddle J, Polyakova O, Rella M, Smith KJ, Thorpe JH, Wang Y, White GV, Young RJ, Hovnanian A.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1454-1458. doi: 10.1016/j.bmcl.2019.04.022. Epub 2019 Apr 12.

PMID:
31005442
3.

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

Wyllie S, Brand S, Thomas M, De Rycker M, Chung CW, Pena I, Bingham RP, Bueren-Calabuig JA, Cantizani J, Cebrian D, Craggs PD, Ferguson L, Goswami P, Hobrath J, Howe J, Jeacock L, Ko EJ, Korczynska J, MacLean L, Manthri S, Martinez MS, Mata-Cantero L, Moniz S, Nühs A, Osuna-Cabello M, Pinto E, Riley J, Robinson S, Rowland P, Simeons FRC, Shishikura Y, Spinks D, Stojanovski L, Thomas J, Thompson S, Viayna Gaza E, Wall RJ, Zuccotto F, Horn D, Ferguson MAJ, Fairlamb AH, Fiandor JM, Martin J, Gray DW, Miles TJ, Gilbert IH, Read KD, Marco M, Wyatt PG.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9318-9323. doi: 10.1073/pnas.1820175116. Epub 2019 Apr 8.

4.

Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening.

Borthwick JA, Ancellin N, Bertrand SM, Bingham RP, Carter PS, Chung CW, Churcher I, Dodic N, Fournier C, Francis PL, Hobbs A, Jamieson C, Pickett SD, Smith SE, Somers DO, Spitzfaden C, Suckling CJ, Young RJ.

J Med Chem. 2016 Mar 24;59(6):2452-67. doi: 10.1021/acs.jmedchem.5b01607. Epub 2016 Mar 16.

5.

The role of university and college counseling centers in advancing the professionalization of psychology.

Bingham RP.

Am Psychol. 2015 Nov;70(8):792-6. doi: 10.1037/a0039638.

PMID:
26618974
6.

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.

Bertrand SM, Ancellin N, Beaufils B, Bingham RP, Borthwick JA, Boullay AB, Boursier E, Carter PS, Chung CW, Churcher I, Dodic N, Fouchet MH, Fournier C, Francis PL, Gummer LA, Herry K, Hobbs A, Hobbs CI, Homes P, Jamieson C, Nicodeme E, Pickett SD, Reid IH, Simpson GL, Sloan LA, Smith SE, Somers DO, Spitzfaden C, Suckling CJ, Valko K, Washio Y, Young RJ.

J Med Chem. 2015 Sep 24;58(18):7140-63. doi: 10.1021/acs.jmedchem.5b00313. Epub 2015 Jul 2.

PMID:
26090771
7.

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, Lind KE, Locke K, Maller C, Martinod K, Patten C, Polyakova O, Rise CE, Rüdiger M, Sheppard RJ, Slade DJ, Thomas P, Thorpe J, Yao G, Drewes G, Wagner DD, Thompson PR, Prinjha RK, Wilson DM.

Nat Chem Biol. 2015 Mar;11(3):189-91. doi: 10.1038/nchembio.1735. Epub 2015 Jan 26.

8.

Psychotherapy termination: clinical and ethical responsibilities.

Vasquez MJ, Bingham RP, Barnett JE.

J Clin Psychol. 2008 May;64(5):653-65. doi: 10.1002/jclp.20478.

PMID:
18415948
9.

The diversification of psychology: a multicultural revolution.

Sue DW, Bingham RP, Porché-Burke L, Vasquez M.

Am Psychol. 1999 Dec;54(12):1061-9.

PMID:
15332527
10.

Becoming a competent clinician: basic competencies in intervention.

Spruill J, Rozensky RH, Stigall TT, Vasquez M, Bingham RP, De Vaney Olvey C.

J Clin Psychol. 2004 Jul;60(7):741-54.

PMID:
15195337
11.

A modular, fully integrated ultra-high-throughput screening system based on confocal fluorescence analysis techniques.

Jäger S, Garbow N, Kirsch A, Preckel H, Gandenberger FU, Herrenknecht K, Rüdiger M, Hutchinson JP, Bingham RP, Ramon F, Bardera A, Martin J.

J Biomol Screen. 2003 Dec;8(6):648-59.

PMID:
14711390
12.

Introduction: a report on the National Multicultural Conference and Summit II.

Bingham RP, Porché-Burke L, James S, Sue DW, Vasquez MJ.

Cultur Divers Ethnic Minor Psychol. 2002 May;8(2):75-87.

PMID:
11987593
13.

Real experiences of uHTS: a prototypic 1536-well fluorescence anisotropy-based uHTS screen and application of well-level quality control procedures.

Turconi S, Shea K, Ashman S, Fantom K, Earnshaw DL, Bingham RP, Haupts UM, Brown MJ, Pope AJ.

J Biomol Screen. 2001 Oct;6(5):275-90.

PMID:
11689128

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