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Items: 43


SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite.

Dion C, Roche S, Laberthonnière C, Broucqsault N, Mariot V, Xue S, Gurzau AD, Nowak A, Gordon CT, Gaillard MC, El-Yazidi C, Thomas M, Schlupp-Robaglia A, Missirian C, Malan V, Ratbi L, Sefiani A, Wollnik B, Binetruy B, Salort Campana E, Attarian S, Bernard R, Nguyen K, Amiel J, Dumonceaux J, Murphy JM, Déjardin J, Blewitt ME, Reversade B, Robin JD, Magdinier F.

Nucleic Acids Res. 2019 Apr 8;47(6):2822-2839. doi: 10.1093/nar/gkz005.


Brown-like adipose progenitors derived from human induced pluripotent stem cells: Identification of critical pathways governing their adipogenic capacity.

Hafner AL, Contet J, Ravaud C, Yao X, Villageois P, Suknuntha K, Annab K, Peraldi P, Binetruy B, Slukvin II, Ladoux A, Dani C.

Sci Rep. 2016 Aug 31;6:32490. doi: 10.1038/srep32490.


Efficient and cost-effective generation of mature neurons from human induced pluripotent stem cells.

Badja C, Maleeva G, El-Yazidi C, Barruet E, Lasserre M, Tropel P, Binetruy B, Bregestovski P, Magdinier F.

Stem Cells Transl Med. 2014 Dec;3(12):1467-72. doi: 10.5966/sctm.2014-0024. Epub 2014 Oct 29.


A p38MAPK-p53 cascade regulates mesodermal differentiation and neurogenesis of embryonic stem cells.

Hadjal Y, Hadadeh O, Yazidi CE, Barruet E, Binétruy B.

Cell Death Dis. 2013 Jul 25;4:e737. doi: 10.1038/cddis.2013.246.


The plasminogen activation system modulates differently adipogenesis and myogenesis of embryonic stem cells.

Hadadeh O, Barruet E, Peiretti F, Verdier M, Bernot D, Hadjal Y, Yazidi CE, Robaglia-Schlupp A, De Paula AM, Nègre D, Iacovino M, Kyba M, Alessi MC, Binétruy B.

PLoS One. 2012;7(11):e49065. doi: 10.1371/journal.pone.0049065. Epub 2012 Nov 8.


Tie1 deficiency induces endothelial-mesenchymal transition.

Garcia J, Sandi MJ, Cordelier P, Binétruy B, Pouysségur J, Iovanna JL, Tournaire R.

EMBO Rep. 2012 May 1;13(5):431-9. doi: 10.1038/embor.2012.29.


p38 mitogen activated protein kinase controls two successive-steps during the early mesodermal commitment of embryonic stem cells.

Barruet E, Hadadeh O, Peiretti F, Renault VM, Hadjal Y, Bernot D, Tournaire R, Negre D, Juhan-Vague I, Alessi MC, Binétruy B.

Stem Cells Dev. 2011 Jul;20(7):1233-46. doi: 10.1089/scd.2010.0213. Epub 2010 Nov 24.


Deficiency in the extracellular signal-regulated kinase 1 (ERK1) protects leptin-deficient mice from insulin resistance without affecting obesity.

Jager J, Corcelle V, Grémeaux T, Laurent K, Waget A, Pagès G, Binétruy B, Le Marchand-Brustel Y, Burcelin R, Bost F, Tanti JF.

Diabetologia. 2011 Jan;54(1):180-9. doi: 10.1007/s00125-010-1944-0. Epub 2010 Oct 15.


Are reviewers obstructing stem cell research?

Binetruy B.

Stem Cells Cloning. 2010 Aug 31;3:103-4. doi: 10.2147/SCCAA.S13491. eCollection 2010. No abstract available.


p38MAP Kinase activity is required for human primary adipocyte differentiation.

Aouadi M, Jager J, Laurent K, Gonzalez T, Cormont M, Binétruy B, Le Marchand-Brustel Y, Tanti JF, Bost F.

FEBS Lett. 2007 Dec 11;581(29):5591-6. Epub 2007 Nov 13.


Concise review: regulation of embryonic stem cell lineage commitment by mitogen-activated protein kinases.

Binétruy B, Heasley L, Bost F, Caron L, Aouadi M.

Stem Cells. 2007 May;25(5):1090-5. Epub 2007 Jan 11. Review.


[Obesity, diabetes and insulin resistance. Alterations of insulin signalling].

Le Marchand-Brustel Y, Gual P, Aouadi M, Grémeaux T, Binétruy B, Bost F, Tanti JF.

J Soc Biol. 2006;200(1):93-7. Review. French.


Long-term treatment with lopinavir-ritonavir induces a reduction in peripheral adipose depots in mice.

Prot M, Heripret L, Cardot-Leccia N, Perrin C, Aouadi M, Lavrut T, Garraffo R, Dellamonica P, Durant J, Le Marchand-Brustel Y, Binétruy B.

Antimicrob Agents Chemother. 2006 Dec;50(12):3998-4004. Epub 2006 Sep 25. Erratum in: Antimicrob Agents Chemother. 2007 Apr;51(4):1587.


Role of MAPKs in development and differentiation: lessons from knockout mice.

Aouadi M, Binetruy B, Caron L, Le Marchand-Brustel Y, Bost F.

Biochimie. 2006 Sep;88(9):1091-8. Epub 2006 Jun 27. Review.


Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages.

Aouadi M, Laurent K, Prot M, Le Marchand-Brustel Y, Binétruy B, Bost F.

Diabetes. 2006 Feb;55(2):281-9.


p38 mitogen-activated protein kinase activity commits embryonic stem cells to either neurogenesis or cardiomyogenesis.

Aouadi M, Bost F, Caron L, Laurent K, Le Marchand Brustel Y, Binétruy B.

Stem Cells. 2006 May;24(5):1399-406. Epub 2006 Jan 19.


A new role for the oncogenic high-mobility group A2 transcription factor in myogenesis of embryonic stem cells.

Caron L, Bost F, Prot M, Hofman P, Binétruy B.

Oncogene. 2005 Sep 15;24(41):6281-91.


The Lac repressor provides a reversible gene expression system in undifferentiated and differentiated embryonic stem cell.

Caron L, Prot M, Rouleau M, Rolando M, Bost F, Binétruy B.

Cell Mol Life Sci. 2005 Jul;62(14):1605-12.


The role of MAPKs in adipocyte differentiation and obesity.

Bost F, Aouadi M, Caron L, Binétruy B.

Biochimie. 2005 Jan;87(1):51-6. Review.


The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis.

Bost F, Aouadi M, Caron L, Even P, Belmonte N, Prot M, Dani C, Hofman P, Pagès G, Pouysségur J, Le Marchand-Brustel Y, Binétruy B.

Diabetes. 2005 Feb;54(2):402-11.


Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage.

Bost F, Caron L, Marchetti I, Dani C, Le Marchand-Brustel Y, Binétruy B.

Biochem J. 2002 Feb 1;361(Pt 3):621-7.


The defective transforming phenotype of c-Jun Ala(63/73) is rescued by mutation of the C-terminal phosphorylation site.

Bost F, Caron L, Vial E, Montreau N, Marchetti I, Dejong V, Defize L, Castellazzi M, Binétruy B.

Oncogene. 2001 Nov 1;20(50):7425-9.


The Wilms' tumor gene product represses the transcription of thrombospondin 1 in response to overexpression of c-Jun.

Dejong V, Degeorges A, Filleur S, Ait-Si-Ali S, Mettouchi A, Bornstein P, Binétruy B, Cabon F.

Oncogene. 1999 May 20;18(20):3143-51.


Protein kinase-dependent overexpression of the nuclear protein pirin in c-JUN and RAS transformed fibroblasts.

Bergman AC, Alaiya AA, Wendler W, Binetruy B, Shoshan M, Sakaguchi K, Bergman T, Kronenwett U, Auer G, Appella E, Jörnvall H, Linder S.

Cell Mol Life Sci. 1999 Mar;55(3):467-71.


Down-regulation of tropomyosin-2 expression in c-Jun-transformed rat fibroblasts involves induction of a MEK1-dependent autocrine loop.

Ljungdahl S, Linder S, Franzén B, Binétruy B, Auer G, Shoshan MC.

Cell Growth Differ. 1998 Jul;9(7):565-73.


The c-Jun-induced transformation process involves complex regulation of tenascin-C expression.

Mettouchi A, Cabon F, Montreau N, Dejong V, Vernier P, Gherzi R, Mercier G, Binétruy B.

Mol Cell Biol. 1997 Jun;17(6):3202-9.


Conditional requirement for sequences distinct from the replication origin during episomal establishment of the BPV1 genome.

Pierrefite V, Binetruy B, Rassoulzadegan M, Cuzin F.

Biochem Biophys Res Commun. 1996 Dec 13;229(2):445-8.


Mechanisms in interleukin-2 protection against glucocorticoid-induced apoptosis: regulation of AP-1 and glucocorticoid receptor transcriptional activities.

Guizani L, Perrin-Wolff M, Breard J, Binetruy B, Bertoglio J.

J Interferon Cytokine Res. 1996 Aug;16(8):601-9.


SPARC and thrombospondin genes are repressed by the c-jun oncogene in rat embryo fibroblasts.

Mettouchi A, Cabon F, Montreau N, Vernier P, Mercier G, Blangy D, Tricoire H, Vigier P, Binétruy B.

EMBO J. 1994 Dec 1;13(23):5668-78.


junB promoter regulation: Ras mediated transactivation by c-Ets-1 and c-Ets-2.

Coffer P, de Jonge M, Mettouchi A, Binetruy B, Ghysdael J, Kruijer W.

Oncogene. 1994 Mar;9(3):911-21.


Control of AP-1 activity by signal transduction cascades.

Lin A, Smeal T, Binetruy B, Deng T, Chambard JC, Karin M.

Adv Second Messenger Phosphoprotein Res. 1993;28:255-60. Review. No abstract available.


Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73.

Smeal T, Binetruy B, Mercola D, Grover-Bardwick A, Heidecker G, Rapp UR, Karin M.

Mol Cell Biol. 1992 Aug;12(8):3507-13.


Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.

Smeal T, Binetruy B, Mercola DA, Birrer M, Karin M.

Nature. 1991 Dec 12;354(6353):494-6.


The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells.

Alani R, Brown P, Binétruy B, Dosaka H, Rosenberg RK, Angel P, Karin M, Birrer MJ.

Mol Cell Biol. 1991 Dec;11(12):6286-95.


Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain.

Binétruy B, Smeal T, Karin M.

Nature. 1991 May 9;351(6322):122-7.


Successive steps in the process of immortalization identified by transfer of separate bovine papillomavirus genes into rat fibroblasts.

Cerni C, Binétruy B, Schiller JT, Lowy DR, Meneguzzi G, Cuzin F.

Proc Natl Acad Sci U S A. 1989 May;86(9):3266-70.


The transformed phenotype in culture and tumorigenicity of Fischer rat fibroblast cells (FR3T3) transformed with bovine papilloma virus type 1.

Grisoni M, Meneguzzi G, de Lapeyrière O, Binétruy B, Rassoulzadegan M, Cuzin F.

Virology. 1984 Jun;135(2):406-16.


High frequency of gene transfer after fusion between bacteria and eukaryotic cells.

Rassoulzadegan M, Binetruy B, Cuzin F.

Nature. 1982 Jan 21;295(5846):257-9. No abstract available.


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