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Items: 1 to 50 of 73

1.

Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models.

De Rossi P, Andrew RJ, Musial TF, Buggia-Prevot V, Xu G, Ponnusamy M, Ly H, Krause SV, Rice RC, de l'Estoile V, Valin T, Salem S, Despa F, Borchelt DR, Bindokas VP, Nicholson DA, Thinakaran G.

Brain Pathol. 2018 Nov 30. doi: 10.1111/bpa.12687. [Epub ahead of print]

PMID:
30506549
2.

Nondestructive, multiplex three-dimensional mapping of immune infiltrates in core needle biopsy.

Lee SS, Bindokas VP, Lingen MW, Kron SJ.

Lab Invest. 2018 Nov 6. doi: 10.1038/s41374-018-0156-y. [Epub ahead of print]

PMID:
30401959
3.

Multiplex Three-Dimensional Mapping of Macromolecular Drug Distribution in the Tumor Microenvironment.

Lee SS, Bindokas VP, Kron SJ.

Mol Cancer Ther. 2019 Jan;18(1):213-226. doi: 10.1158/1535-7163.MCT-18-0554. Epub 2018 Oct 15.

PMID:
30322947
4.

Multiplex three-dimensional optical mapping of tumor immune microenvironment.

Lee SS, Bindokas VP, Kron SJ.

Sci Rep. 2017 Dec 5;7(1):17031. doi: 10.1038/s41598-017-16987-x.

5.

Improved deconvolution of very weak confocal signals.

Day KJ, La Rivière PJ, Chandler T, Bindokas VP, Ferrier NJ, Glick BS.

Version 2. F1000Res. 2017 Jun 6 [revised 2017 Jan 1];6:787. doi: 10.12688/f1000research.11773.2. eCollection 2017.

6.

Light Activation of Calcein Inhibits Vesicle Release of Catecholamines.

Miller BA, Papke JB, Bindokas VP, Harkins AB.

ACS Chem Neurosci. 2017 Oct 18;8(10):2309-2314. doi: 10.1021/acschemneuro.7b00225. Epub 2017 Aug 9.

PMID:
28707873
7.

Mitochondrial mechanisms of neuronal rescue by F-68, a hydrophilic Pluronic block co-polymer, following acute substrate deprivation.

Wang JC, Bindokas VP, Skinner M, Emrick T, Marks JD.

Neurochem Int. 2017 Oct;109:126-140. doi: 10.1016/j.neuint.2017.04.007. Epub 2017 Apr 19. Review.

8.

Critical role of microbiota within cecal crypts on the regenerative capacity of the intestinal epithelium following surgical stress.

Zaborin A, Krezalek M, Hyoju S, Defazio JR, Setia N, Belogortseva N, Bindokas VP, Guo Q, Zaborina O, Alverdy JC.

Am J Physiol Gastrointest Liver Physiol. 2017 Feb 1;312(2):G112-G122. doi: 10.1152/ajpgi.00294.2016. Epub 2016 Dec 15.

9.

Tumor-associated fibroblasts predominantly come from local and not circulating precursors.

Arina A, Idel C, Hyjek EM, Alegre ML, Wang Y, Bindokas VP, Weichselbaum RR, Schreiber H.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7551-6. doi: 10.1073/pnas.1600363113. Epub 2016 Jun 17.

10.

Drug-Paired Contextual Stimuli Increase Dendritic Spine Dynamics in Select Nucleus Accumbens Neurons.

Singer BF, Bubula N, Li D, Przybycien-Szymanska MM, Bindokas VP, Vezina P.

Neuropsychopharmacology. 2016 Jul;41(8):2178-87. doi: 10.1038/npp.2016.39. Epub 2016 Mar 16.

11.

TRPC6 channel translocation into phagosomal membrane augments phagosomal function.

Riazanski V, Gabdoulkhakova AG, Boynton LS, Eguchi RR, Deriy LV, Hogarth DK, Loaëc N, Oumata N, Galons H, Brown ME, Shevchenko P, Gallan AJ, Yoo SG, Naren AP, Villereal ML, Beacham DW, Bindokas VP, Birnbaumer L, Meijer L, Nelson DJ.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6486-95. doi: 10.1073/pnas.1518966112. Epub 2015 Nov 10.

12.

Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.

Zhong R, Bao R, Faber PW, Bindokas VP, Bechill J, Lingen MW, Spiotto MT.

Cancer Res. 2015 Sep 15;75(18):3958-3969. doi: 10.1158/0008-5472.CAN-15-0199. Epub 2015 Aug 20.

13.

Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy.

Cortes CJ, Qin K, Norstrom EM, Green WN, Bindokas VP, Mastrianni JA.

Int J Cell Biol. 2013;2013:560421. doi: 10.1155/2013/560421. Epub 2013 Dec 17.

14.

Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase.

Buggia-Prévot V, Fernandez CG, Riordan S, Vetrivel KS, Roseman J, Waters J, Bindokas VP, Vassar R, Thinakaran G.

Mol Neurodegener. 2014 Jan 4;9:1. doi: 10.1186/1750-1326-9-1.

15.

A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production.

Buggia-Prévot V, Fernandez CG, Udayar V, Vetrivel KS, Elie A, Roseman J, Sasse VA, Lefkow M, Meckler X, Bhattacharyya S, George M, Kar S, Bindokas VP, Parent AT, Rajendran L, Band H, Vassar R, Thinakaran G.

Cell Rep. 2013 Dec 26;5(6):1552-63. doi: 10.1016/j.celrep.2013.12.006.

16.

SLIT3-ROBO4 activation promotes vascular network formation in human engineered tissue and angiogenesis in vivo.

Paul JD, Coulombe KLK, Toth PT, Zhang Y, Marsboom G, Bindokas VP, Smith DW, Murry CE, Rehman J.

J Mol Cell Cardiol. 2013 Nov;64:124-31. doi: 10.1016/j.yjmcc.2013.09.005.

17.

Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.

Kawada I, Hasina R, Lennon FE, Bindokas VP, Usatyuk P, Tan YH, Krishnaswamy S, Arif Q, Carey G, Hseu RD, Robinson M, Tretiakova M, Brand TM, Iida M, Ferguson MK, Wheeler DL, Husain AN, Natarajan V, Vokes EE, Singleton PA, Salgia R.

Cancer Biol Ther. 2013 Jul;14(7):679-91. doi: 10.4161/cbt.25091. Epub 2013 May 31.

18.

Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice.

Gong P, Roseman J, Fernandez CG, Vetrivel KS, Bindokas VP, Zitzow LA, Kar S, Parent AT, Thinakaran G.

Mol Neurodegener. 2011 Dec 28;6:87. doi: 10.1186/1750-1326-6-87.

19.

Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors.

Efimova EV, Mauceri HJ, Golden DW, Labay E, Bindokas VP, Darga TE, Chakraborty C, Barreto-Andrade JC, Crawley C, Sutton HG, Kron SJ, Weichselbaum RR.

Cancer Res. 2010 Aug 1;70(15):6277-82. doi: 10.1158/0008-5472.CAN-09-4224. Epub 2010 Jul 7.

20.

Disease-causing mutations in the cystic fibrosis transmembrane conductance regulator determine the functional responses of alveolar macrophages.

Deriy LV, Gomez EA, Zhang G, Beacham DW, Hopson JA, Gallan AJ, Shevchenko PD, Bindokas VP, Nelson DJ.

J Biol Chem. 2009 Dec 18;284(51):35926-38. doi: 10.1074/jbc.M109.057372.

21.

The granular chloride channel ClC-3 is permissive for insulin secretion.

Deriy LV, Gomez EA, Jacobson DA, Wang X, Hopson JA, Liu XY, Zhang G, Bindokas VP, Philipson LH, Nelson DJ.

Cell Metab. 2009 Oct;10(4):316-23. doi: 10.1016/j.cmet.2009.08.012.

22.

Expression of NR2B in cerebellar granule cells specifically facilitates effect of motor training on motor learning.

Jiao J, Nakajima A, Janssen WG, Bindokas VP, Xiong X, Morrison JH, Brorson JR, Tang YP.

PLoS One. 2008 Feb 27;3(2):e1684. doi: 10.1371/journal.pone.0001684.

23.

Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.

Jagadeeswaran R, Surawska H, Krishnaswamy S, Janamanchi V, Mackinnon AC, Seiwert TY, Loganathan S, Kanteti R, Reichman T, Nallasura V, Schwartz S, Faoro L, Wang YC, Girard L, Tretiakova MS, Ahmed S, Zumba O, Soulii L, Bindokas VP, Szeto LL, Gordon GJ, Bueno R, Sugarbaker D, Lingen MW, Sattler M, Krausz T, Vigneswaran W, Natarajan V, Minna J, Vokes EE, Ferguson MK, Husain AN, Salgia R.

Cancer Res. 2008 Jan 1;68(1):132-42. doi: 10.1158/0008-5472.CAN-07-1998.

24.

Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.

Jagadeeswaran R, Jagadeeswaran S, Bindokas VP, Salgia R.

Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1488-94. Epub 2007 Feb 23.

25.

Flow cytometric analysis of phosphorylated histone H2AX following exposure to ionizing radiation in human microvascular endothelial cells.

Kataoka Y, Bindokas VP, Duggan RC, Murley JS, Grdina DJ.

J Radiat Res. 2006 Nov;47(3-4):245-57. Epub 2006 Sep 6.

26.

Visualizing calcium signaling in cells by digitized wide-field and confocal fluorescent microscopy.

Roe MW, Fiekers JF, Philipson LH, Bindokas VP.

Methods Mol Biol. 2006;319:37-66.

PMID:
16719350
27.

Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.

Jagadeeswaran R, Ma PC, Seiwert TY, Jagadeeswaran S, Zumba O, Nallasura V, Ahmed S, Filiberti R, Paganuzzi M, Puntoni R, Kratzke RA, Gordon GJ, Sugarbaker DJ, Bueno R, Janamanchi V, Bindokas VP, Kindler HL, Salgia R.

Cancer Res. 2006 Jan 1;66(1):352-61.

28.

Imaging pancreatic beta-cells in the intact pancreas.

Hara M, Dizon RF, Glick BS, Lee CS, Kaestner KH, Piston DW, Bindokas VP.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E1041-7. Epub 2005 Dec 20.

29.

Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells.

Tamarina NA, Kuznetsov A, Rhodes CJ, Bindokas VP, Philipson LH.

Diabetes. 2005 Nov;54(11):3073-81.

30.

High resolution optical imaging of infarction in intact organs.

Hara M, Noiseux N, Bindokas VP.

Biotechniques. 2005 Sep;39(3):373-6.

31.

FRET-based voltage probes for confocal imaging: membrane potential oscillations throughout pancreatic islets.

Kuznetsov A, Bindokas VP, Marks JD, Philipson LH.

Am J Physiol Cell Physiol. 2005 Jul;289(1):C224-9. Epub 2005 Mar 9.

32.

A mouse model for studying intrahepatic islet transplantation.

Hara M, Yin D, Dizon RF, Shen J, Chong AS, Bindokas VP.

Transplantation. 2004 Aug 27;78(4):615-8.

33.

Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion.

Ma L, Bindokas VP, Kuznetsov A, Rhodes C, Hays L, Edwardson JM, Ueda K, Steiner DF, Philipson LH.

Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9266-71. Epub 2004 Jun 14.

34.

A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.

Zhou YP, Sreenan S, Pan CY, Currie KP, Bindokas VP, Horikawa Y, Lee JP, Ostrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KS.

Metabolism. 2003 May;52(5):528-34.

PMID:
12759879
35.

Visualizing superoxide production in normal and diabetic rat islets of Langerhans.

Bindokas VP, Kuznetsov A, Sreenan S, Polonsky KS, Roe MW, Philipson LH.

J Biol Chem. 2003 Mar 14;278(11):9796-801. Epub 2003 Jan 4.

36.

Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.

Hara M, Wang X, Kawamura T, Bindokas VP, Dizon RF, Alcoser SY, Magnuson MA, Bell GI.

Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E177-83. Epub 2002 Sep 17.

37.

Polyglutamine protein aggregates are dynamic.

Kim S, Nollen EA, Kitagawa K, Bindokas VP, Morimoto RI.

Nat Cell Biol. 2002 Oct;4(10):826-31.

PMID:
12360295
38.

No correlation between aggregates of Cu/Zn superoxide dismutase and cell death in familial amyotrophic lateral sclerosis.

Lee JP, Gerin C, Bindokas VP, Miller R, Ghadge G, Roos RP.

J Neurochem. 2002 Sep;82(5):1229-38.

39.

Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors.

Li C, Fox CJ, Master SR, Bindokas VP, Chodosh LA, Thompson CB.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9830-5. Epub 2002 Jul 12.

40.

Quantal release of free radicals during exocytosis of phagosomes.

Di A, Krupa B, Bindokas VP, Chen Y, Brown ME, Palfrey HC, Naren AP, Kirk KL, Nelson DJ.

Nat Cell Biol. 2002 Apr;4(4):279-85.

PMID:
11901421
41.

Molecular components of tolerance to opiates in single hippocampal neurons.

Bushell T, Endoh T, Simen AA, Ren D, Bindokas VP, Miller RJ.

Mol Pharmacol. 2002 Jan;61(1):55-64.

42.

The C terminus of the Ca channel alpha1B subunit mediates selective inhibition by G-protein-coupled receptors.

Simen AA, Lee CC, Simen BB, Bindokas VP, Miller RJ.

J Neurosci. 2001 Oct 1;21(19):7587-97.

43.

Subcellular localization of calcium-permeable AMPA receptors in spinal motoneurons.

Vandenberghe W, Bindokas VP, Miller RJ, Robberecht W, Brorson JR.

Eur J Neurosci. 2001 Jul;14(2):305-14.

PMID:
11553281
44.

Tetrahydrobiopterin scavenges superoxide in dopaminergic neurons.

Nakamura K, Bindokas VP, Kowlessur D, Elas M, Milstien S, Marks JD, Halpern HJ, Kang UJ.

J Biol Chem. 2001 Sep 14;276(37):34402-7. Epub 2001 Jul 10.

45.

Maturation of vulnerability to excitotoxicity: intracellular mechanisms in cultured postnatal hippocampal neurons.

Marks JD, Bindokas VP, Zhang XM.

Brain Res Dev Brain Res. 2000 Nov 30;124(1-2):101-16.

PMID:
11113517
46.

The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited.

Nakamura K, Bindokas VP, Marks JD, Wright DA, Frim DM, Miller RJ, Kang UJ.

Mol Pharmacol. 2000 Aug;58(2):271-8.

47.

Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion.

Zhou YP, Pena JC, Roe MW, Mittal A, Levisetti M, Baldwin AC, Pugh W, Ostrega D, Ahmed N, Bindokas VP, Philipson LH, Hanahan D, Thompson CB, Polonsky KS.

Am J Physiol Endocrinol Metab. 2000 Feb;278(2):E340-51.

48.

The role of immunophilins in mutant superoxide dismutase-1linked familial amyotrophic lateral sclerosis.

Lee JP, Palfrey HC, Bindokas VP, Ghadge GD, Ma L, Miller RJ, Roos RP.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3251-6.

49.

Changes in mitochondrial function resulting from synaptic activity in the rat hippocampal slice.

Bindokas VP, Lee CC, Colmers WF, Miller RJ.

J Neurosci. 1998 Jun 15;18(12):4570-87.

50.

Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection.

Ghadge GD, Lee JP, Bindokas VP, Jordan J, Ma L, Miller RJ, Roos RP.

J Neurosci. 1997 Nov 15;17(22):8756-66.

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