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Items: 1 to 50 of 702

1.

pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components.

Marini F, Binder H.

BMC Bioinformatics. 2019 Jun 13;20(1):331. doi: 10.1186/s12859-019-2879-1.

2.

Hypertension and multiple cardiovascular risk factors increase the risk for retinal vein occlusions: results from the Gutenberg Retinal Vein Occlusion Study.

Ponto KA, Scharrer I, Binder H, Korb C, Rosner AK, Ehlers TO, Rieser N, Grübel NC, Rossmann H, Wild PS, Feltgen N, Pfeiffer N, Mirshahi A.

J Hypertens. 2019 Jul;37(7):1372-1383. doi: 10.1097/HJH.0000000000002057.

PMID:
31145709
3.

Population Levels Assessment of the Distribution of Disease-Associated Variants With Emphasis on Armenians - A Machine Learning Approach.

Nikoghosyan M, Hakobyan S, Hovhannisyan A, Loeffler-Wirth H, Binder H, Arakelyan A.

Front Genet. 2019 Apr 26;10:394. doi: 10.3389/fgene.2019.00394. eCollection 2019.

4.

A modular transcriptome map of mature B cell lymphomas.

Loeffler-Wirth H, Kreuz M, Hopp L, Arakelyan A, Haake A, Cogliatti SB, Feller AC, Hansmann ML, Lenze D, Möller P, Müller-Hermelink HK, Fortenbacher E, Willscher E, Ott G, Rosenwald A, Pott C, Schwaenen C, Trautmann H, Wessendorf S, Stein H, Szczepanowski M, Trümper L, Hummel M, Klapper W, Siebert R, Loeffler M, Binder H; German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma.

Genome Med. 2019 Apr 30;11(1):27. doi: 10.1186/s13073-019-0637-7.

5.

DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development.

Binder H, Willscher E, Loeffler-Wirth H, Hopp L, Jones DTW, Pfister SM, Kreuz M, Gramatzki D, Fortenbacher E, Hentschel B, Tatagiba M, Herrlinger U, Vatter H, Matschke J, Westphal M, Krex D, Schackert G, Tonn JC, Schlegel U, Steiger HJ, Wick W, Weber RG, Weller M, Loeffler M.

Acta Neuropathol Commun. 2019 Apr 25;7(1):59. doi: 10.1186/s40478-019-0704-8.

6.

Meta-analyses identify differentially expressed micrornas in Parkinson's disease.

Schulz J, Takousis P, Wohlers I, Itua IOG, Dobricic V, Rücker G, Binder H, Middleton L, Ioannidis JPA, Perneczky R, Bertram L, Lill CM.

Ann Neurol. 2019 Jun;85(6):835-851. doi: 10.1002/ana.25490.

PMID:
30990912
7.

A Queue-Poll Extension and DataSHIELD: Standardised, Monitored, Indirect and Secure Access to Sensitive Data.

Gruendner J, Prokosch HU, Schindler S, Lenz S, Binder H.

Stud Health Technol Inform. 2019;258:115-119.

PMID:
30942726
8.

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma.

López C, Kleinheinz K, Aukema SM, Rohde M, Bernhart SH, Hübschmann D, Wagener R, Toprak UH, Raimondi F, Kreuz M, Waszak SM, Huang Z, Sieverling L, Paramasivam N, Seufert J, Sungalee S, Russell RB, Bausinger J, Kretzmer H, Ammerpohl O, Bergmann AK, Binder H, Borkhardt A, Brors B, Claviez A, Doose G, Feuerbach L, Haake A, Hansmann ML, Hoell J, Hummel M, Korbel JO, Lawerenz C, Lenze D, Radlwimmer B, Richter J, Rosenstiel P, Rosenwald A, Schilhabel MB, Stein H, Stilgenbauer S, Stadler PF, Szczepanowski M, Weniger MA, Zapatka M, Eils R, Lichter P, Loeffler M, Möller P, Trümper L, Klapper W; ICGC MMML-Seq Consortium, Hoffmann S, Küppers R, Burkhardt B, Schlesner M, Siebert R.

Nat Commun. 2019 Mar 29;10(1):1459. doi: 10.1038/s41467-019-08578-3.

9.

Genetic Determinants of Ototoxicity During and After Childhood Cancer Treatment: Protocol for the PanCareLIFE Study.

Clemens E, Meijer AJ, Broer L, Langer T, van der Kooi AL, Uitterlinden AG, de Vries A, Kuehni CE, Garrè ML, Kepak T, Kruseova J, Winther JF, Kremer LC, van Dulmen-den Broeder E, Tissing WJ, Rechnitzer C, Kenborg L, Hasle H, Grabow D, Parfitt R, Binder H, Carleton BC, Byrne J, Kaatsch P, Am Zehnhoff-Dinnesen A, Zolk O, van den Heuvel-Eibrink MM.

JMIR Res Protoc. 2019 Mar 19;8(3):e11868. doi: 10.2196/11868.

10.

The buried knot technique for all inside graft link preparation leads to superior biomechanical graft link stability.

Tiefenboeck TM, Hirtler L, Winnisch M, Binder H, Koch T, Komjati M, Hofbauer M, Ostermann RC.

Sci Rep. 2019 Feb 6;9(1):1488. doi: 10.1038/s41598-018-38150-w.

11.

Promoter-proximal pausing mediated by the exon junction complex regulates splicing.

Akhtar J, Kreim N, Marini F, Mohana G, Brüne D, Binder H, Roignant JY.

Nat Commun. 2019 Jan 31;10(1):521. doi: 10.1038/s41467-019-08381-0.

12.

Feasibility and utility of a cognitive screening for risk stratification in hospitalized older patients.

Geschke K, Weyer-Elberich V, Mueller AK, Binder H, Fellgiebel A.

Int J Geriatr Psychiatry. 2019 Apr;34(4):588-593. doi: 10.1002/gps.5056. Epub 2019 Jan 18.

PMID:
30588672
13.

Investigation of intraocular pressure fluctuation as a risk factor of glaucoma progression.

Matlach J, Bender S, König J, Binder H, Pfeiffer N, Hoffmann EM.

Clin Ophthalmol. 2018 Dec 18;13:9-16. doi: 10.2147/OPTH.S186526. eCollection 2019.

14.

Transcriptome 3'end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma.

Ogorodnikov A, Levin M, Tattikota S, Tokalov S, Hoque M, Scherzinger D, Marini F, Poetsch A, Binder H, Macher-Göppinger S, Probst HC, Tian B, Schaefer M, Lackner KJ, Westermann F, Danckwardt S.

Nat Commun. 2018 Dec 14;9(1):5331. doi: 10.1038/s41467-018-07580-5.

15.

Fatigue in survivors of malignant melanoma and its determinants: a register-based cohort study.

Tibubos AN, Ernst M, Brähler E, Fischbeck S, Hinz A, Blettner M, Zeissig SR, Weyer V, Imruck BH, Binder H, Beutel ME.

Support Care Cancer. 2018 Dec 11. doi: 10.1007/s00520-018-4587-1. [Epub ahead of print]

PMID:
30539313
16.

Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome.

Nührenberg TG, Cederqvist M, Marini F, Stratz C, Grüning BA, Trenk D, Binder H, Gilsbach R, Neumann FJ, Hein L.

Biomed Res Int. 2018 Nov 1;2018:8989252. doi: 10.1155/2018/8989252. eCollection 2018.

17.

Intake of Vitamin K Antagonists and Worsening of Cardiac and Vascular Disease: Results From the Population-Based Gutenberg Health Study.

Eggebrecht L, Prochaska JH, Schulz A, Arnold N, Jünger C, Göbel S, Laubert-Reh D, Binder H, Beutel ME, Pfeiffer N, Blankenberg S, Lackner KJ, Spronk HM, Ten Cate H, Münzel T, Wild PS.

J Am Heart Assoc. 2018 Sep 4;7(17):e008650. doi: 10.1161/JAHA.118.008650.

18.

Norovirus Gastroenteritis among Hospitalized Patients, Germany, 2007-2012.

Kowalzik F, Binder H, Zöller D, Riera-Montes M, Clemens R, Verstraeten T, Zepp F.

Emerg Infect Dis. 2018 Nov;24(11):2021-2028. doi: 10.3201/eid2411.170820.

19.

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

Byrne J, Grabow D, Campbell H, O'Brien K, Bielack S, Am Zehnhoff-Dinnesen A, Calaminus G, Kremer L, Langer T, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, Baust K, Bautz A, Beck JD, Berger C, Binder H, Borgmann-Staudt A, Broer L, Cario H, Casagranda L, Clemens E, Deuster D, de Vries A, Dirksen U, Falck Winther J, Fosså S, Font-Gonzalez A, Grandage V, Haupt R, Hecker-Nolting S, Hjorth L, Kaiser M, Kenborg L, Kepak T, Kepáková K, Knudsen LE, Krawczuk-Rybak M, Kruseova J, Kuehni CE, Kunstreich M, Kuonen R, Lackner H, Leiper A, Loeffen EAH, Luks A, Modan-Moses D, Mulder R, Parfitt R, Paul NW, Ranft A, Ruud E, Schilling R, Spix C, Stefanowicz J, Strauβ G, Uitterlinden AG, van den Berg M, van der Kooi AL, van Dijk M, van Leeuwen F, Zolk O, Zöller D, Kaatsch P; PanCareLIFE consortium.

Eur J Cancer. 2018 Nov;103:227-237. doi: 10.1016/j.ejca.2018.08.007. Epub 2018 Sep 29.

PMID:
30273888
20.

Comparison of a sports-hydration drink containing high amylose starch with usual hydration practice in Australian rules footballers during intense summer training.

O'Connell SM, Woodman RJ, Brown IL, Vincent DJ, Binder HJ, Ramakrishna BS, Young GP.

J Int Soc Sports Nutr. 2018 Sep 21;15(1):46. doi: 10.1186/s12970-018-0253-8.

21.

Power of the Wilcoxon-Mann-Whitney test for non-inferiority in the presence of death-censored observations.

Schmidtmann I, Konstantinides S, Binder H.

Biom J. 2018 Sep 19. doi: 10.1002/bimj.201700296. [Epub ahead of print]

PMID:
30230574
22.

Longitudinal anthropometry of children and adolescents using 3D-body scanning.

Loeffler-Wirth H, Vogel M, Kirsten T, Glock F, Poulain T, Körner A, Loeffler M, Kiess W, Binder H.

PLoS One. 2018 Sep 13;13(9):e0203628. doi: 10.1371/journal.pone.0203628. eCollection 2018.

23.

Modeling Activity Tracker Data Using Deep Boltzmann Machines.

Treppner M, Lenz S, Binder H, Zöller D.

Stud Health Technol Inform. 2018;253:155-159.

PMID:
30147063
24.

BAL Cell Gene Expression Is Indicative of Outcome and Airway Basal Cell Involvement in Idiopathic Pulmonary Fibrosis.

Prasse A, Binder H, Schupp JC, Kayser G, Bargagli E, Jaeger B, Hess M, Rittinghausen S, Vuga L, Lynn H, Violette S, Jung B, Quast K, Vanaudenaerde B, Xu Y, Hohlfeld JM, Krug N, Herazo-Maya JD, Rottoli P, Wuyts WA, Kaminski N.

Am J Respir Crit Care Med. 2019 Mar 1;199(5):622-630. doi: 10.1164/rccm.201712-2551OC.

PMID:
30141961
25.

Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome.

Hopp L, Loeffler-Wirth H, Nersisyan L, Arakelyan A, Binder H.

Front Immunol. 2018 Jul 17;9:1620. doi: 10.3389/fimmu.2018.01620. eCollection 2018.

26.

MIRACUM: Medical Informatics in Research and Care in University Medicine.

Prokosch HU, Acker T, Bernarding J, Binder H, Boeker M, Boerries M, Daumke P, Ganslandt T, Hesser J, Höning G, Neumaier M, Marquardt K, Renz H, Rothkötter HJ, Schade-Brittinger C, Schmücker P, Schüttler J, Sedlmayr M, Serve H, Sohrabi K, Storf H.

Methods Inf Med. 2018 Jul;57(S 01):e82-e91. doi: 10.3414/ME17-02-0025. Epub 2018 Jul 17.

27.

RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas.

Kunz M, Löffler-Wirth H, Dannemann M, Willscher E, Doose G, Kelso J, Kottek T, Nickel B, Hopp L, Landsberg J, Hoffmann S, Tüting T, Zigrino P, Mauch C, Utikal J, Ziemer M, Schulze HJ, Hölzel M, Roesch A, Kneitz S, Meierjohann S, Bosserhoff A, Binder H, Schartl M.

Oncogene. 2018 Nov;37(47):6136-6151. doi: 10.1038/s41388-018-0385-y. Epub 2018 Jul 11.

PMID:
29995873
28.

Mechanisms and modulators of cognitive training gain transfer in cognitively healthy aging: study protocol of the AgeGain study.

Wolf D, Tüscher O, Teipel S, Mierau A, Strüder H, Drzezga A, Baier B, Binder H, Fellgiebel A; German AgeGain study group.

Trials. 2018 Jun 27;19(1):337. doi: 10.1186/s13063-018-2688-2.

29.

Combined SOM-portrayal of gene expression and DNA methylation landscapes disentangles modes of epigenetic regulation in glioblastoma.

Hopp L, Löffler-Wirth H, Galle J, Binder H.

Epigenomics. 2018 Jun;10(6):745-764. doi: 10.2217/epi-2017-0140. Epub 2018 Jun 11.

PMID:
29888966
30.

Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness.

Lamparter J, Schmidtmann I, Schuster AK, Siouli A, Wasielica-Poslednik J, Mirshahi A, Höhn R, Unterrainer J, Wild PS, Binder H, Lackner K, Beutel ME, Münzel T, Pfeiffer N, Hoffmann EM.

PLoS One. 2018 May 22;13(5):e0197682. doi: 10.1371/journal.pone.0197682. eCollection 2018.

31.

Determinants of illness-specific social support and its relation to distress in long-term melanoma survivors.

Fischbeck S, Weyer-Elberich V, Zeissig SR, Imruck BH, Blettner M, Binder H, Beutel ME.

BMC Public Health. 2018 Apr 17;18(1):511. doi: 10.1186/s12889-018-5401-1.

32.

Pseudotime Dynamics in Melanoma Single-Cell Transcriptomes Reveals Different Mechanisms of Tumor Progression.

Loeffler-Wirth H, Binder H, Willscher E, Gerber T, Kunz M.

Biology (Basel). 2018 Apr 3;7(2). pii: E23. doi: 10.3390/biology7020023.

33.

The immune contexture of hepatocellular carcinoma predicts clinical outcome.

Foerster F, Hess M, Gerhold-Ay A, Marquardt JU, Becker D, Galle PR, Schuppan D, Binder H, Bockamp E.

Sci Rep. 2018 Mar 29;8(1):5351. doi: 10.1038/s41598-018-21937-2.

34.

The use of the LARS system in the treatment of AC joint instability - Long-term results after a mean of 7.4 years.

Tiefenboeck TM, Boesmueller S, Popp D, Payr S, Joestl J, Binder H, Schurz M, Komjati M, Fialka C, Ostermann RC.

Orthop Traumatol Surg Res. 2018 Oct;104(6):749-754. doi: 10.1016/j.otsr.2018.02.010. Epub 2018 Mar 23.

PMID:
29581067
35.

Time-to-first-event versus recurrent-event analysis: points to consider for selecting a meaningful analysis strategy in clinical trials with composite endpoints.

Rauch G, Kieser M, Binder H, Bayes-Genis A, Jahn-Eimermacher A.

Clin Res Cardiol. 2018 May;107(5):437-443. doi: 10.1007/s00392-018-1205-7. Epub 2018 Feb 16.

PMID:
29453594
36.

Common neural structures activated by epidural and transcutaneous lumbar spinal cord stimulation: Elicitation of posterior root-muscle reflexes.

Hofstoetter US, Freundl B, Binder H, Minassian K.

PLoS One. 2018 Jan 30;13(1):e0192013. doi: 10.1371/journal.pone.0192013. eCollection 2018.

37.

Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study.

Klok FA, Ageno W, Barco S, Binder H, Brenner B, Duerschmied D, Empen K, Faggiano P, Ficker JH, Galiè N, Ghuysen A, Held M, Heydenreich N, Huisman MV, Jiménez D, Kozak M, Lang IM, Lankeit M, Münzel T, Petris A, Pruszczyk P, Quitzau K, Schellong S, Schmidt KH, Stefanovic BS, Verschuren F, Wolf-Puetz A, Meyer G, Konstantinides SV; PEITHO-2 Investigators.

Thromb Haemost. 2017 Dec;117(12):2425-2434. doi: 10.1160/TH17-06-0434. Epub 2017 Dec 6.

PMID:
29212130
38.

On the necessity and design of studies comparing statistical methods.

Boulesteix AL, Binder H, Abrahamowicz M, Sauerbrei W; Simulation Panel of the STRATOS Initiative.

Biom J. 2018 Jan;60(1):216-218. doi: 10.1002/bimj.201700129. Epub 2017 Nov 29. No abstract available.

PMID:
29193206
39.

Recruiting former melanoma patients via hospitals in comparison to office-based dermatologists in a register-based cohort study that required indirect contact.

Zeissig SR, Weyer-Elberich V, Emrich K, Binder H, Fischbeck S, Imruck BH, Friedrich-Mai P, Beutel ME, Blettner M.

BMC Med Res Methodol. 2017 Nov 22;17(1):150. doi: 10.1186/s12874-017-0425-2.

40.

Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles.

Arakelyan A, Nersisyan L, Poghosyan D, Khondkaryan L, Hakobyan A, Löffler-Wirth H, Melanitou E, Binder H.

PLoS One. 2017 Nov 3;12(11):e0187572. doi: 10.1371/journal.pone.0187572. eCollection 2017.

41.

Body typing of children and adolescents using 3D-body scanning.

Loeffler-Wirth H, Vogel M, Kirsten T, Glock F, Poulain T, Körner A, Loeffler M, Kiess W, Binder H.

PLoS One. 2017 Oct 20;12(10):e0186881. doi: 10.1371/journal.pone.0186881. eCollection 2017.

42.

IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits.

Rohde K, Klös M, Hopp L, Liu X, Keller M, Stumvoll M, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Kovacs P, Binder H, Blüher M, Böttcher Y.

Sci Rep. 2017 Sep 28;7(1):12369. doi: 10.1038/s41598-017-12393-5.

43.

Defining patient centricity with patients for patients and caregivers: a collaborative endeavour.

Yeoman G, Furlong P, Seres M, Binder H, Chung H, Garzya V, Jones RR.

BMJ Innov. 2017 Apr;3(2):76-83. doi: 10.1136/bmjinnov-2016-000157. Epub 2017 Mar 24.

44.

Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours.

Yurugi H, Marini F, Weber C, David K, Zhao Q, Binder H, Désaubry L, Rajalingam K.

Oncogene. 2017 Oct 19;36(42):5914. doi: 10.1038/onc.2017.307. Epub 2017 Aug 28.

PMID:
28846116
45.

Acromioclavicular joint dislocation treated with Bosworth screw and additional K-wiring: results after 7.8 years - still an adequate procedure?

Tiefenboeck TM, Popp D, Boesmueller S, Payr S, Joestl J, Komjati M, Binder H, Schurz M, Ostermann RC.

BMC Musculoskelet Disord. 2017 Aug 4;18(1):339. doi: 10.1186/s12891-017-1692-0.

46.

Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis - Data from the Population-based Gutenberg Health Study.

Arnold N, Gori T, Schnabel RB, Schulz A, Prochaska JH, Zeller T, Binder H, Pfeiffer N, Beutel M, Espinola-Klein C, Lackner KJ, Blankenberg S, Münzel T, Wild PS.

Sci Rep. 2017 Jul 24;7(1):6346. doi: 10.1038/s41598-017-06175-2.

47.

Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome.

Binder H, Hopp L, Schweiger MR, Hoffmann S, Jühling F, Kerick M, Timmermann B, Siebert S, Grimm C, Nersisyan L, Arakelyan A, Herberg M, Buske P, Loeffler-Wirth H, Rosolowski M, Engel C, Przybilla J, Peifer M, Friedrichs N, Moeslein G, Odenthal M, Hussong M, Peters S, Holzapfel S, Nattermann J, Hueneburg R, Schmiegel W, Royer-Pokora B, Aretz S, Kloth M, Kloor M, Buettner R, Galle J, Loeffler M.

J Pathol. 2017 Oct;243(2):242-254. doi: 10.1002/path.4948. Epub 2017 Sep 5.

PMID:
28727142
48.

Improving the Patient Experience by Implementing an ICU Diary for Those at Risk of Post-intensive Care Syndrome.

Blair KTA, Eccleston SD, Binder HM, McCarthy MS.

J Patient Exp. 2017 Mar;4(1):4-9. doi: 10.1177/2374373517692927. Epub 2017 Feb 9.

49.

Comparison of Different Hypotheses Regarding the Spread of Alzheimer's Disease Using Markov Random Fields and Multimodal Imaging.

Dyrba M, Grothe MJ, Mohammadi A, Binder H, Kirste T, Teipel SJ; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2018;65(3):731-746. doi: 10.3233/JAD-161197.

PMID:
28697557
50.

European core curriculum in neurorehabilitation.

Sandrini G, Binder H, Hömberg V, Saltuari L, Tarkka I, Smania N, Corradini C, Giustini A, Kätterer C, Picari L, Diserens K, Koenig E, Geurts A, Anghelescu A, Opara J, Tonin P, Kwakkel G, Golyk V, Onose G, Pérennou D, Picelli A.

Funct Neurol. 2017 Apr/Jun;32(2):63-68.

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