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Items: 1 to 50 of 66

1.

The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids.

Ducastel S, Touche V, Trabelsi MS, Boulinguiez A, Butruille L, Nawrot M, Peschard S, Chávez-Talavera O, Dorchies E, Vallez E, Annicotte JS, Lancel S, Briand O, Bantubungi K, Caron S, Bindels LB, Delzenne NM, Tailleux A, Staels B, Lestavel S.

Sci Rep. 2020 Jan 13;10(1):174. doi: 10.1038/s41598-019-56743-x.

2.

Food for thought about manipulating gut bacteria.

Delzenne NM, Bindels LB.

Nature. 2020 Jan;577(7788):32-34. doi: 10.1038/d41586-019-03704-z. No abstract available.

PMID:
31863062
3.

The Janus Face of Cereals: Wheat-Derived Prebiotics Counteract the Detrimental Effect of Gluten on Metabolic Homeostasis in Mice Fed a High-Fat/High-Sucrose Diet.

Olivares M, Rodriguez J, Pötgens SA, Neyrinck AM, Cani PD, Bindels LB, Delzenne NM.

Mol Nutr Food Res. 2019 Dec;63(24):e1900632. doi: 10.1002/mnfr.201900632. Epub 2019 Nov 11.

PMID:
31608562
4.

Chitin-glucan and pomegranate polyphenols improve endothelial dysfunction.

Neyrinck AM, Catry E, Taminiau B, Cani PD, Bindels LB, Daube G, Dessy C, Delzenne NM.

Sci Rep. 2019 Oct 2;9(1):14150. doi: 10.1038/s41598-019-50700-4.

5.

Targeting the Gut Microbiota to Treat Cachexia.

Genton L, Mareschal J, Charretier Y, Lazarevic V, Bindels LB, Schrenzel J.

Front Cell Infect Microbiol. 2019 Sep 12;9:305. doi: 10.3389/fcimb.2019.00305. eCollection 2019. Review.

6.

Functional Effects of EPS-Producing Bifidobacterium Administration on Energy Metabolic Alterations of Diet-Induced Obese Mice.

Salazar N, Neyrinck AM, Bindels LB, Druart C, Ruas-Madiedo P, Cani PD, de Los Reyes-Gavilán CG, Delzenne NM.

Front Microbiol. 2019 Aug 7;10:1809. doi: 10.3389/fmicb.2019.01809. eCollection 2019.

7.

Gut microbiota and osteoarthritis management: An expert consensus of the European society for clinical and economic aspects of osteoporosis, osteoarthritis and musculoskeletal diseases (ESCEO).

Biver E, Berenbaum F, Valdes AM, Araujo de Carvalho I, Bindels LB, Brandi ML, Calder PC, Castronovo V, Cavalier E, Cherubini A, Cooper C, Dennison E, Franceschi C, Fuggle N, Laslop A, Miossec P, Thomas T, Tuzun S, Veronese N, Vlaskovska M, Reginster JY, Rizzoli R.

Ageing Res Rev. 2019 Nov;55:100946. doi: 10.1016/j.arr.2019.100946. Epub 2019 Aug 19. Review.

8.

Effects of a diet based on inulin-rich vegetables on gut health and nutritional behavior in healthy humans.

Hiel S, Bindels LB, Pachikian BD, Kalala G, Broers V, Zamariola G, Chang BPI, Kambashi B, Rodriguez J, Cani PD, Neyrinck AM, Thissen JP, Luminet O, Bindelle J, Delzenne NM.

Am J Clin Nutr. 2019 Jun 1;109(6):1683-1695. doi: 10.1093/ajcn/nqz001.

9.

A Preventive Prebiotic Supplementation Improves the Sweet Taste Perception in Diet-Induced Obese Mice.

Bernard A, Ancel D, Neyrinck AM, Dastugue A, Bindels LB, Delzenne NM, Besnard P.

Nutrients. 2019 Mar 5;11(3). pii: E549. doi: 10.3390/nu11030549.

10.

Contribution of the gut microbiota to the regulation of host metabolism and energy balance: a focus on the gut-liver axis.

Delzenne NM, Knudsen C, Beaumont M, Rodriguez J, Neyrinck AM, Bindels LB.

Proc Nutr Soc. 2019 Aug;78(3):319-328. doi: 10.1017/S0029665118002756. Epub 2019 Jan 10.

PMID:
30628563
11.

Milk Polar Lipids in a High-Fat Diet Can Prevent Body Weight Gain: Modulated Abundance of Gut Bacteria in Relation with Fecal Loss of Specific Fatty Acids.

Milard M, Laugerette F, Durand A, Buisson C, Meugnier E, Loizon E, Louche-Pelissier C, Sauvinet V, Garnier L, Viel S, Bertrand K, Joffre F, Cheillan D, Humbert L, Rainteau D, Plaisancié P, Bindels LB, Neyrinck AM, Delzenne NM, Michalski MC.

Mol Nutr Food Res. 2019 Feb;63(4):e1801078. doi: 10.1002/mnfr.201801078. Epub 2019 Jan 25.

PMID:
30628158
12.

Commensal Escherichia coli Strains Can Promote Intestinal Inflammation via Differential Interleukin-6 Production.

Kittana H, Gomes-Neto JC, Heck K, Geis AL, Segura Muñoz RR, Cody LA, Schmaltz RJ, Bindels LB, Sinha R, Hostetter JM, Benson AK, Ramer-Tait AE.

Front Immunol. 2018 Oct 9;9:2318. doi: 10.3389/fimmu.2018.02318. eCollection 2018.

13.

The Potential Role of the Dipeptidyl Peptidase-4-Like Activity From the Gut Microbiota on the Host Health.

Olivares M, Schüppel V, Hassan AM, Beaumont M, Neyrinck AM, Bindels LB, Benítez-Páez A, Sanz Y, Haller D, Holzer P, Delzenne NM.

Front Microbiol. 2018 Aug 22;9:1900. doi: 10.3389/fmicb.2018.01900. eCollection 2018.

14.

Polyunsaturated fatty acids, polyphenols, amino acids, prebiotics: can they help to tackle cancer cachexia and related inflammation?

Pötgens SA, Sboarina M, Bindels LB.

Curr Opin Clin Nutr Metab Care. 2018 Nov;21(6):458-464. doi: 10.1097/MCO.0000000000000505. Review.

PMID:
30138138
15.

Klebsiella oxytoca expands in cancer cachexia and acts as a gut pathobiont contributing to intestinal dysfunction.

Pötgens SA, Brossel H, Sboarina M, Catry E, Cani PD, Neyrinck AM, Delzenne NM, Bindels LB.

Sci Rep. 2018 Aug 17;8(1):12321. doi: 10.1038/s41598-018-30569-5.

16.

Increased Serpina3n release into circulation during glucocorticoid-mediated muscle atrophy.

Gueugneau M, d'Hose D, Barbé C, de Barsy M, Lause P, Maiter D, Bindels LB, Delzenne NM, Schaeffer L, Gangloff YG, Chambon C, Coudy-Gandilhon C, Béchet D, Thissen JP.

J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):929-946. doi: 10.1002/jcsm.12315. Epub 2018 Jul 10.

17.

Microbiome metabolomics reveals new drivers of human liver steatosis.

Delzenne NM, Bindels LB.

Nat Med. 2018 Jul;24(7):906-907. doi: 10.1038/s41591-018-0126-3. No abstract available.

PMID:
29988145
18.

The gut microbiota metabolite indole alleviates liver inflammation in mice.

Beaumont M, Neyrinck AM, Olivares M, Rodriguez J, de Rocca Serra A, Roumain M, Bindels LB, Cani PD, Evenepoel P, Muccioli GG, Demoulin JB, Delzenne NM.

FASEB J. 2018 Jun 15:fj201800544. doi: 10.1096/fj.201800544. [Epub ahead of print]

19.

The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice.

Olivares M, Neyrinck AM, Pötgens SA, Beaumont M, Salazar N, Cani PD, Bindels LB, Delzenne NM.

Diabetologia. 2018 Aug;61(8):1838-1848. doi: 10.1007/s00125-018-4647-6. Epub 2018 May 25.

20.

Increased gut permeability in cancer cachexia: mechanisms and clinical relevance.

Bindels LB, Neyrinck AM, Loumaye A, Catry E, Walgrave H, Cherbuy C, Leclercq S, Van Hul M, Plovier H, Pachikian B, Bermúdez-Humarán LG, Langella P, Cani PD, Thissen JP, Delzenne NM.

Oncotarget. 2018 Apr 6;9(26):18224-18238. doi: 10.18632/oncotarget.24804. eCollection 2018 Apr 6.

21.

Inulin Improves Postprandial Hypertriglyceridemia by Modulating Gene Expression in the Small Intestine.

Hiel S, Neyrinck AM, Rodriguez J, Pachikian BD, Bouzin C, Thissen JP, Cani PD, Bindels LB, Delzenne NM.

Nutrients. 2018 Apr 25;10(5). pii: E532. doi: 10.3390/nu10050532.

22.

Wheat-derived arabinoxylan oligosaccharides with bifidogenic properties abolishes metabolic disorders induced by western diet in mice.

Neyrinck AM, Hiel S, Bouzin C, Campayo VG, Cani PD, Bindels LB, Delzenne NM.

Nutr Diabetes. 2018 Mar 7;8(1):15. doi: 10.1038/s41387-018-0019-z.

23.

Implication of trans-11,trans-13 conjugated linoleic acid in the development of hepatic steatosis.

Pachikian BD, Druart C, Catry E, Bindels LB, Neyrinck AM, Larondelle Y, Cani PD, Delzenne NM.

PLoS One. 2018 Feb 1;13(2):e0192447. doi: 10.1371/journal.pone.0192447. eCollection 2018.

24.

Gut microbiota in 2017: Contribution of gut microbiota-host cooperation to drug efficacy.

Delzenne NM, Bindels LB.

Nat Rev Gastroenterol Hepatol. 2018 Feb;15(2):69-70. doi: 10.1038/nrgastro.2017.170. Epub 2017 Dec 20. No abstract available.

PMID:
29259330
25.

Galactooligosaccharide supplementation provides protection against Citrobacter rodentium-induced colitis without limiting pathogen burden.

Kittana H, Quintero-Villegas MI, Bindels LB, Gomes-Neto JC, Schmaltz RJ, Segura Munoz RR, Cody LA, Moxley RA, Hostetter J, Hutkins RW, Ramer-Tait AE.

Microbiology. 2018 Feb;164(2):154-162. doi: 10.1099/mic.0.000593. Epub 2017 Dec 19.

26.

A gut pathobiont synergizes with the microbiota to instigate inflammatory disease marked by immunoreactivity against other symbionts but not itself.

Gomes-Neto JC, Kittana H, Mantz S, Segura Munoz RR, Schmaltz RJ, Bindels LB, Clarke J, Hostetter JM, Benson AK, Walter J, Ramer-Tait AE.

Sci Rep. 2017 Dec 18;7(1):17707. doi: 10.1038/s41598-017-18014-5.

27.

Ffar2 expression regulates leukaemic cell growth in vivo.

Bindels LB, Porporato PE, Ducastel S, Sboarina M, Neyrinck AM, Dewulf EM, Feron O, Lestavel S, Cani PD, Staels B, Sonveaux P, Delzenne NM.

Br J Cancer. 2017 Oct 24;117(9):1336-1340. doi: 10.1038/bjc.2017.307. Epub 2017 Sep 5.

28.

A polyphenolic extract from green tea leaves activates fat browning in high-fat-diet-induced obese mice.

Neyrinck AM, Bindels LB, Geurts L, Van Hul M, Cani PD, Delzenne NM.

J Nutr Biochem. 2017 Nov;49:15-21. doi: 10.1016/j.jnutbio.2017.07.008. Epub 2017 Jul 24.

PMID:
28863365
29.

How do probiotics and prebiotics function at distant sites?

Reid G, Abrahamsson T, Bailey M, Bindels LB, Bubnov R, Ganguli K, Martoni C, O'Neill C, Savignac HM, Stanton C, Ship N, Surette M, Tuohy K, van Hemert S.

Benef Microbes. 2017 Aug 24;8(4):521-533. doi: 10.3920/BM2016.0222. Epub 2017 Jul 20. Review.

PMID:
28726511
30.

Fat binding capacity and modulation of the gut microbiota both determine the effect of wheat bran fractions on adiposity.

Suriano F, Bindels LB, Verspreet J, Courtin CM, Verbeke K, Cani PD, Neyrinck AM, Delzenne NM.

Sci Rep. 2017 Jul 17;7(1):5621. doi: 10.1038/s41598-017-05698-y.

31.

Spirulina Protects against Hepatic Inflammation in Aging: An Effect Related to the Modulation of the Gut Microbiota?

Neyrinck AM, Taminiau B, Walgrave H, Daube G, Cani PD, Bindels LB, Delzenne NM.

Nutrients. 2017 Jun 20;9(6). pii: E633. doi: 10.3390/nu9060633.

32.

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

Catry E, Bindels LB, Tailleux A, Lestavel S, Neyrinck AM, Goossens JF, Lobysheva I, Plovier H, Essaghir A, Demoulin JB, Bouzin C, Pachikian BD, Cani PD, Staels B, Dessy C, Delzenne NM.

Gut. 2018 Feb;67(2):271-283. doi: 10.1136/gutjnl-2016-313316. Epub 2017 Apr 4.

33.

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior.

Leclercq S, Mian FM, Stanisz AM, Bindels LB, Cambier E, Ben-Amram H, Koren O, Forsythe P, Bienenstock J.

Nat Commun. 2017 Apr 4;8:15062. doi: 10.1038/ncomms15062.

34.

Resistant starch can improve insulin sensitivity independently of the gut microbiota.

Bindels LB, Segura Munoz RR, Gomes-Neto JC, Mutemberezi V, Martínez I, Salazar N, Cody EA, Quintero-Villegas MI, Kittana H, de Los Reyes-Gavilán CG, Schmaltz RJ, Muccioli GG, Walter J, Ramer-Tait AE.

Microbiome. 2017 Feb 7;5(1):12. doi: 10.1186/s40168-017-0230-5.

35.

Colonic acetate in obesity: location matters!

Bindels LB, Leclercq I.

Clin Sci (Lond). 2016 Nov 1;130(22):2083-2086.

PMID:
27729473
36.

Intestinal Sucrase as a Novel Target Contributing to the Regulation of Glycemia by Prebiotics.

Neyrinck AM, Pachikian B, Taminiau B, Daube G, Frédérick R, Cani PD, Bindels LB, Delzenne NM.

PLoS One. 2016 Aug 17;11(8):e0160488. doi: 10.1371/journal.pone.0160488. eCollection 2016.

37.

Rhubarb extract prevents hepatic inflammation induced by acute alcohol intake, an effect related to the modulation of the gut microbiota.

Neyrinck AM, Etxeberria U, Taminiau B, Daube G, Van Hul M, Everard A, Cani PD, Bindels LB, Delzenne NM.

Mol Nutr Food Res. 2017 Jan;61(1). doi: 10.1002/mnfr.201500899. Epub 2016 Jun 1.

38.

Disparate Metabolic Responses in Mice Fed a High-Fat Diet Supplemented with Maize-Derived Non-Digestible Feruloylated Oligo- and Polysaccharides Are Linked to Changes in the Gut Microbiota.

Yang J, Bindels LB, Segura Munoz RR, Martínez I, Walter J, Ramer-Tait AE, Rose DJ.

PLoS One. 2016 Jan 5;11(1):e0146144. doi: 10.1371/journal.pone.0146144. eCollection 2016.

39.

Synbiotic approach restores intestinal homeostasis and prolongs survival in leukaemic mice with cachexia.

Bindels LB, Neyrinck AM, Claus SP, Le Roy CI, Grangette C, Pot B, Martinez I, Walter J, Cani PD, Delzenne NM.

ISME J. 2016 Jun;10(6):1456-70. doi: 10.1038/ismej.2015.209. Epub 2015 Nov 27.

40.

Prebiotics: why definitions matter.

Hutkins RW, Krumbeck JA, Bindels LB, Cani PD, Fahey G Jr, Goh YJ, Hamaker B, Martens EC, Mills DA, Rastal RA, Vaughan E, Sanders ME.

Curr Opin Biotechnol. 2016 Feb;37:1-7. doi: 10.1016/j.copbio.2015.09.001. Epub 2015 Sep 29. Review.

41.

Resistant starches for the management of metabolic diseases.

Bindels LB, Walter J, Ramer-Tait AE.

Curr Opin Clin Nutr Metab Care. 2015 Nov;18(6):559-65. doi: 10.1097/MCO.0000000000000223. Review.

42.

Gut microbiota: Ganoderma lucidum, a new prebiotic agent to treat obesity?

Delzenne NM, Bindels LB.

Nat Rev Gastroenterol Hepatol. 2015 Oct;12(10):553-4. doi: 10.1038/nrgastro.2015.137. Epub 2015 Aug 18.

PMID:
26284561
43.

Gut microorganisms as promising targets for the management of type 2 diabetes.

Delzenne NM, Cani PD, Everard A, Neyrinck AM, Bindels LB.

Diabetologia. 2015 Oct;58(10):2206-17. doi: 10.1007/s00125-015-3712-7. Epub 2015 Jul 31. Review.

PMID:
26224102
44.

Non Digestible Oligosaccharides Modulate the Gut Microbiota to Control the Development of Leukemia and Associated Cachexia in Mice.

Bindels LB, Neyrinck AM, Salazar N, Taminiau B, Druart C, Muccioli GG, François E, Blecker C, Richel A, Daube G, Mahillon J, de los Reyes-Gavilán CG, Cani PD, Delzenne NM.

PLoS One. 2015 Jun 22;10(6):e0131009. doi: 10.1371/journal.pone.0131009. eCollection 2015.

45.

Intake of Lactobacillus reuteri improves incretin and insulin secretion in glucose-tolerant humans: a proof of concept.

Simon MC, Strassburger K, Nowotny B, Kolb H, Nowotny P, Burkart V, Zivehe F, Hwang JH, Stehle P, Pacini G, Hartmann B, Holst JJ, MacKenzie C, Bindels LB, Martinez I, Walter J, Henrich B, Schloot NC, Roden M.

Diabetes Care. 2015 Oct;38(10):1827-34. doi: 10.2337/dc14-2690. Epub 2015 Jun 17.

PMID:
26084343
46.

Towards a more comprehensive concept for prebiotics.

Bindels LB, Delzenne NM, Cani PD, Walter J.

Nat Rev Gastroenterol Hepatol. 2015 May;12(5):303-10. doi: 10.1038/nrgastro.2015.47. Epub 2015 Mar 31. Review.

PMID:
25824997
47.

Ability of the gut microbiota to produce PUFA-derived bacterial metabolites: Proof of concept in germ-free versus conventionalized mice.

Druart C, Bindels LB, Schmaltz R, Neyrinck AM, Cani PD, Walter J, Ramer-Tait AE, Delzenne NM.

Mol Nutr Food Res. 2015 Aug;59(8):1603-13. doi: 10.1002/mnfr.201500014. Epub 2015 May 12.

48.

Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status.

Everard A, Geurts L, Caesar R, Van Hul M, Matamoros S, Duparc T, Denis RG, Cochez P, Pierard F, Castel J, Bindels LB, Plovier H, Robine S, Muccioli GG, Renauld JC, Dumoutier L, Delzenne NM, Luquet S, Bäckhed F, Cani PD.

Nat Commun. 2014 Dec 5;5:5648. doi: 10.1038/ncomms6648.

49.

Inulin-type fructans modulate intestinal Bifidobacterium species populations and decrease fecal short-chain fatty acids in obese women.

Salazar N, Dewulf EM, Neyrinck AM, Bindels LB, Cani PD, Mahillon J, de Vos WM, Thissen JP, Gueimonde M, de Los Reyes-Gavilán CG, Delzenne NM.

Clin Nutr. 2015 Jun;34(3):501-7. doi: 10.1016/j.clnu.2014.06.001. Epub 2014 Jun 11.

PMID:
24969566
50.

Can prebiotics and probiotics improve therapeutic outcomes for undernourished individuals?

Sheridan PO, Bindels LB, Saulnier DM, Reid G, Nova E, Holmgren K, O'Toole PW, Bunn J, Delzenne N, Scott KP.

Gut Microbes. 2014 Jan-Feb;5(1):74-82. doi: 10.4161/gmic.27252. Epub 2013 Dec 16.

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