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Items: 5

1.

Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations.

Almeida MQ, Azevedo MF, Xekouki P, Bimpaki EI, Horvath A, Collins MT, Karaviti LP, Jeha GS, Bhattacharyya N, Cheadle C, Watkins T, Bourdeau I, Nesterova M, Stratakis CA.

J Clin Endocrinol Metab. 2012 Apr;97(4):E687-93. doi: 10.1210/jc.2011-3000. Epub 2012 Jan 18.

2.

Integrated genomic analysis of nodular tissue in macronodular adrenocortical hyperplasia: progression of tumorigenesis in a disorder associated with multiple benign lesions.

Almeida MQ, Harran M, Bimpaki EI, Hsiao HP, Horvath A, Cheadle C, Watkins T, Nesterova M, Stratakis CA.

J Clin Endocrinol Metab. 2011 Apr;96(4):E728-38. doi: 10.1210/jc.2010-2420. Epub 2011 Jan 20.

3.

MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumourigenesis.

Bimpaki EI, Iliopoulos D, Moraitis A, Stratakis CA.

Clin Endocrinol (Oxf). 2010 Jun;72(6):744-51. doi: 10.1111/j.1365-2265.2009.03725.x. Epub 2009 Oct 22.

4.

Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes.

Bimpaki EI, Nesterova M, Stratakis CA.

Eur J Endocrinol. 2009 Jul;161(1):153-61. doi: 10.1530/EJE-09-0027. Epub 2009 May 8.

5.

MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling.

Iliopoulos D, Bimpaki EI, Nesterova M, Stratakis CA.

Cancer Res. 2009 Apr 15;69(8):3278-82. doi: 10.1158/0008-5472.CAN-09-0155. Epub 2009 Apr 7.

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