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Amikacin liposome inhalation suspension for chronic Pseudomonas aeruginosa infection in cystic fibrosis.

Bilton D, Pressler T, Fajac I, Clancy JP, Sands D, Minic P, Cipolli M, Galeva I, Solé A, Quittner AL, Liu K, McGinnis JP 2nd, Eagle G, Gupta R, Konstan MW; CLEAR-108 Study Group.

J Cyst Fibros. 2019 Aug 23. pii: S1569-1993(19)30833-1. doi: 10.1016/j.jcf.2019.08.001. [Epub ahead of print]


Disease progression in patients with cystic fibrosis treated with ivacaftor: Data from national US and UK registries.

Volkova N, Moy K, Evans J, Campbell D, Tian S, Simard C, Higgins M, Konstan MW, Sawicki GS, Elbert A, Charman SC, Marshall BC, Bilton D.

J Cyst Fibros. 2019 Jun 10. pii: S1569-1993(19)30767-2. doi: 10.1016/j.jcf.2019.05.015. [Epub ahead of print]


Randomised cross-over trial evaluating the short-term effects of non-invasive ventilation as an adjunct to airway clearance techniques in adults with cystic fibrosis.

Stanford G, Parrott H, Bilton D, Agent P, Banya W, Simmonds N.

BMJ Open Respir Res. 2019 Apr 14;6(1):e000399. doi: 10.1136/bmjresp-2018-000399. eCollection 2019.


Health State Utility Data in Cystic Fibrosis: A Systematic Review.

Mohindru B, Turner D, Sach T, Bilton D, Carr S, Archangelidi O, Bhadhuri A, Whitty JA.

Pharmacoecon Open. 2019 May 3. doi: 10.1007/s41669-019-0144-1. [Epub ahead of print] Review.


Results from an online survey of adults with cystic fibrosis: Accessing and using life expectancy information.

Keogh RH, Bilton D, Cosgriff R, Kavanagh D, Rayner O, Sedgwick PM.

PLoS One. 2019 Apr 12;14(4):e0213639. doi: 10.1371/journal.pone.0213639. eCollection 2019.


The emerging burden of liver disease in cystic fibrosis patients: A UK nationwide study.

Toledano MB, Mukherjee SK, Howell J, Westaby D, Khan SA, Bilton D, Simmonds NJ.

PLoS One. 2019 Apr 4;14(4):e0212779. doi: 10.1371/journal.pone.0212779. eCollection 2019.


Phylogenomics of the superfamily Dytiscoidea (Coleoptera: Adephaga) with an evaluation of phylogenetic conflict and systematic error.

Vasilikopoulos A, Balke M, Beutel RG, Donath A, Podsiadlowski L, Pflug JM, Waterhouse RM, Meusemann K, Peters RS, Escalona HE, Mayer C, Liu S, Hendrich L, Alarie Y, Bilton DT, Jia F, Zhou X, Maddison DR, Niehuis O, Misof B.

Mol Phylogenet Evol. 2019 Jun;135:270-285. doi: 10.1016/j.ympev.2019.02.022. Epub 2019 Feb 26.


Two new Mesoceration Janssens, 1967 from the Piketberg, South Africa (Coleoptera, Hydraenidae).

Bilton DT, Mlambo MC.

Zootaxa. 2019 Feb 12;4555(2):268-274. doi: 10.11646/zootaxa.4555.2.7.


Identifying exceptional cystic fibrosis care services: combining statistical process control with focus groups.

MacNeill SJ, Pierotti L, Mohammed MA, Wildman M, Boote J, Harrison S, Carr SB, Cullinan P, Elston C, Bilton D.

Southampton (UK): NIHR Journals Library; 2019 Feb.


Health economic modelling in Cystic Fibrosis: A systematic review.

Mohindru B, Turner D, Sach T, Bilton D, Carr S, Archangelidi O, Bhadhuri A, Whitty JA.

J Cyst Fibros. 2019 Jul;18(4):452-460. doi: 10.1016/j.jcf.2019.01.007. Epub 2019 Feb 7. Review.


Inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis and chronic lung infection with Pseudomonas aeruginosa (ORBIT-3 and ORBIT-4): two phase 3, randomised controlled trials.

Haworth CS, Bilton D, Chalmers JD, Davis AM, Froehlich J, Gonda I, Thompson B, Wanner A, O'Donnell AE.

Lancet Respir Med. 2019 Mar;7(3):213-226. doi: 10.1016/S2213-2600(18)30427-2. Epub 2019 Jan 15. Erratum in: Lancet Respir Med. 2019 Jan 25;:.


Water Beetles as Models in Ecology and Evolution.

Bilton DT, Ribera I, Short AEZ.

Annu Rev Entomol. 2019 Jan 7;64:359-377. doi: 10.1146/annurev-ento-011118-111829. Review.


Non-invasive ventilation and clinical outcomes in cystic fibrosis: Findings from the UK CF registry.

Archangelidi O, Carr SB, Simmonds NJ, Bilton D, Banya W, Cullinan P; CF-EpiNet.

J Cyst Fibros. 2019 Sep;18(5):665-670. doi: 10.1016/j.jcf.2018.11.006. Epub 2018 Nov 28.


A new species of Leielmis Delève, 1964, with a revised key to members of the genus (Coleoptera: Elmidae).

Bilton DT.

Zootaxa. 2018 Jun 28;4441(3):592-596. doi: 10.11646/zootaxa.4441.3.11.


Investigating the effects of long-term dornase alfa use on lung function using registry data.

Newsome SJ, Daniel RM, Carr SB, Bilton D, Keogh RH.

J Cyst Fibros. 2019 Jan;18(1):110-117. doi: 10.1016/j.jcf.2018.08.004. Epub 2018 Aug 29.


Data from the US and UK cystic fibrosis registries support disease modification by CFTR modulation with ivacaftor.

Bessonova L, Volkova N, Higgins M, Bengtsson L, Tian S, Simard C, Konstan MW, Sawicki GS, Sewall A, Nyangoma S, Elbert A, Marshall BC, Bilton D.

Thorax. 2018 Aug;73(8):731-740. doi: 10.1136/thoraxjnl-2017-210394. Epub 2018 May 10.


Use of a rare disease patient registry in long-term post-authorisation drug studies: a model for collaboration with industry.

Bilton D, Caine N, Cunningham S, Simmonds NJ, Cosgriff R, Carr SB.

Lancet Respir Med. 2018 Jul;6(7):495-496. doi: 10.1016/S2213-2600(18)30192-9. Epub 2018 May 4. Review. No abstract available.


The Meladema Laporte, 1835 (Coleoptera, Dytiscidae) of the Sahara Desert.

Ribera I, Bilton DT, Cardoso A.

Zootaxa. 2018 Mar 20;4399(1):119-122. doi: 10.11646/zootaxa.4399.1.7.


A new humicolous Parhydraena d'Orchymont, 1937 from South Africa (Coleoptera, Hydraenidae).

Bilton DT.

Zootaxa. 2018 Feb 7;4378(2):284-288. doi: 10.11646/zootaxa.4378.2.9.


The impact of National Cystic Fibrosis Registries: A review series.

Stephenson AL, Bilton D.

J Cyst Fibros. 2018 May;17(3):287-288. doi: 10.1016/j.jcf.2018.04.001. Epub 2018 Apr 21. No abstract available.


Micro-habitat distribution drives patch quality for sub-tropical rocky plateau amphibians in the northern Western Ghats, India.

Thorpe CJ, Lewis TR, Kulkarni S, Watve A, Gaitonde N, Pryce D, Davies L, Bilton DT, Knight ME.

PLoS One. 2018 Mar 26;13(3):e0194810. doi: 10.1371/journal.pone.0194810. eCollection 2018.


The diagnosis and management of respiratory tract fungal infection in cystic fibrosis: A UK survey of current practice.

Boyle M, Moore JE, Whitehouse JL, Bilton D, Downey DG.

Med Mycol. 2019 Feb 1;57(2):155-160. doi: 10.1093/mmy/myy014.


Laboratory Diagnosis and Characterization of Fungal Disease in Patients with Cystic Fibrosis (CF): A Survey of Current UK Practice in a Cohort of Clinical Microbiology Laboratories.

Boyle M, Moore JE, Whitehouse JL, Bilton D, Downey DG.

Mycopathologia. 2018 Aug;183(4):723-729. doi: 10.1007/s11046-018-0251-z. Epub 2018 Mar 2.


Up-to-date and projected estimates of survival for people with cystic fibrosis using baseline characteristics: A longitudinal study using UK patient registry data.

Keogh RH, Szczesniak R, Taylor-Robinson D, Bilton D.

J Cyst Fibros. 2018 Mar;17(2):218-227. doi: 10.1016/j.jcf.2017.11.019. Epub 2018 Jan 6.


Does plasticity in thermal tolerance trade off with inherent tolerance? The influence of setal tracheal gills on thermal tolerance and its plasticity in a group of European diving beetles.

Verberk WCEP, Calosi P, Spicer JI, Kehl S, Bilton DT.

J Insect Physiol. 2018 Apr;106(Pt 3):163-171. doi: 10.1016/j.jinsphys.2017.12.005. Epub 2017 Dec 24.


Data Resource Profile: The UK Cystic Fibrosis Registry.

Taylor-Robinson D, Archangelidi O, Carr SB, Cosgriff R, Gunn E, Keogh RH, MacDougall A, Newsome S, Schlüter DK, Stanojevic S, Bilton D; CF-EpinNet collaboration.

Int J Epidemiol. 2018 Feb 1;47(1):9-10e. doi: 10.1093/ije/dyx196. No abstract available.


The chicken or the egg? Adaptation to desiccation and salinity tolerance in a lineage of water beetles.

Pallarés S, Arribas P, Bilton DT, Millán A, Velasco J, Ribera I.

Mol Ecol. 2017 Oct;26(20):5614-5628. doi: 10.1111/mec.14334. Epub 2017 Sep 14.


Pleistocene range shifts, refugia and the origin of widespread species in western Palaearctic water beetles.

García-Vázquez D, Bilton DT, Foster GN, Ribera I.

Mol Phylogenet Evol. 2017 Sep;114:122-136. doi: 10.1016/j.ympev.2017.06.007. Epub 2017 Jun 15.


Water beetles from the Bokkeveld Plateau: a semi-arid hotspot of freshwater biodiversity in the Northern Cape of South Africa.

Bilton DT.

Zootaxa. 2017 May 16;4268(2):191-214. doi: 10.11646/zootaxa.4268.2.2.


A revision of the South African riffle beetle genus <i>Leielmis</i> Delève, 1964 (Coleoptera: Elmidae).

Bilton DT.

Zootaxa. 2017 Apr 12;4254(2):255-268. doi: 10.11646/zootaxa.4254.2.6.


Pseudomonas aeruginosa adaptation and diversification in the non-cystic fibrosis bronchiectasis lung.

Hilliam Y, Moore MP, Lamont IL, Bilton D, Haworth CS, Foweraker J, Walshaw MJ, Williams D, Fothergill JL, De Soyza A, Winstanley C.

Eur Respir J. 2017 Apr 26;49(4). pii: 1602108. doi: 10.1183/13993003.02108-2016. Print 2017 Apr.


Developing a guideline for structured content and process in mental health nursing handover.

Cowan D, Brunero S, Luo X, Bilton D, Lamont S.

Int J Ment Health Nurs. 2018 Feb;27(1):429-439. doi: 10.1111/inm.12337. Epub 2017 Apr 12.


A treatment evaluator tool to monitor the real-world effectiveness of inhaled aztreonam lysine in cystic fibrosis.

Plant BJ, Downey DG, Eustace JA, Gunaratnam C, Haworth CS, Jones AM, McKone EF, Peckham DG, Ketchell RI, Bilton D.

J Cyst Fibros. 2017 Nov;16(6):695-701. doi: 10.1016/j.jcf.2017.02.006. Epub 2017 Apr 6.


Diversity and distribution of polyphagan water beetles (Coleoptera) in the Lake St Lucia system, South Africa.

Bird MS, Bilton DT, Perissinotto R.

Zookeys. 2017 Feb 14;(656):51-84. doi: 10.3897/zookeys.656.11622. eCollection 2017.


Frequent discordance between morphology and mitochondrial DNA in a species group of European water beetles (Coleoptera: Dytiscidae).

Bilton DT, Turner L, Foster GN.

PeerJ. 2017 Mar 9;5:e3076. doi: 10.7717/peerj.3076. eCollection 2017.


Ethnicity impacts the cystic fibrosis diagnosis: A note of caution.

Bosch B, Bilton D, Sosnay P, Raraigh KS, Mak DYF, Ishiguro H, Gulmans V, Thomas M, Cuppens H, Amaral M, De Boeck K.

J Cyst Fibros. 2017 Jul;16(4):488-491. doi: 10.1016/j.jcf.2017.01.016. Epub 2017 Feb 21.


Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients.

Cox MJ, Turek EM, Hennessy C, Mirza GK, James PL, Coleman M, Jones A, Wilson R, Bilton D, Cookson WO, Moffatt MF, Loebinger MR.

PLoS One. 2017 Feb 7;12(2):e0170622. doi: 10.1371/journal.pone.0170622. eCollection 2017.


Metabolic and reproductive plasticity of core and marginal populations of the eurythermic saline water bug Sigara selecta (Hemiptera: Corixidae) in a climate change context.

Carbonell JA, Bilton DT, Calosi P, Millán A, Stewart A, Velasco J.

J Insect Physiol. 2017 Apr;98:59-66. doi: 10.1016/j.jinsphys.2016.11.015. Epub 2016 Nov 30.


Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.

Bryant JM, Grogono DM, Rodriguez-Rincon D, Everall I, Brown KP, Moreno P, Verma D, Hill E, Drijkoningen J, Gilligan P, Esther CR, Noone PG, Giddings O, Bell SC, Thomson R, Wainwright CE, Coulter C, Pandey S, Wood ME, Stockwell RE, Ramsay KA, Sherrard LJ, Kidd TJ, Jabbour N, Johnson GR, Knibbs LD, Morawska L, Sly PD, Jones A, Bilton D, Laurenson I, Ruddy M, Bourke S, Bowler IC, Chapman SJ, Clayton A, Cullen M, Daniels T, Dempsey O, Denton M, Desai M, Drew RJ, Edenborough F, Evans J, Folb J, Humphrey H, Isalska B, Jensen-Fangel S, Jönsson B, Jones AM, Katzenstein TL, Lillebaek T, MacGregor G, Mayell S, Millar M, Modha D, Nash EF, O'Brien C, O'Brien D, Ohri C, Pao CS, Peckham D, Perrin F, Perry A, Pressler T, Prtak L, Qvist T, Robb A, Rodgers H, Schaffer K, Shafi N, van Ingen J, Walshaw M, Watson D, West N, Whitehouse J, Haworth CS, Harris SR, Ordway D, Parkhill J, Floto RA.

Science. 2016 Nov 11;354(6313):751-757. doi: 10.1126/science.aaf8156.


Phase I Studies of Acebilustat: Biomarker Response and Safety in Patients with Cystic Fibrosis.

Elborn JS, Horsley A, MacGregor G, Bilton D, Grosswald R, Ahuja S, Springman EB.

Clin Transl Sci. 2017 Jan;10(1):28-34. doi: 10.1111/cts.12428. Epub 2016 Nov 2.


Aquatic insects dealing with dehydration: do desiccation resistance traits differ in species with contrasting habitat preferences?

Pallarés S, Velasco J, Millán A, Bilton DT, Arribas P.

PeerJ. 2016 Aug 31;4:e2382. doi: 10.7717/peerj.2382. eCollection 2016.


A new species of Anacaena Thomson, 1859 from South Africa (Coleoptera: Hydrophilidae).

Bilton DT, Komarek A.

Zootaxa. 2016 Jul 22;4139(4):593-9. doi: 10.11646/zootaxa.4139.4.11.


Two new water beetles from the South African Cape (Coleoptera, Hydraenidae).

Bilton DT.

Zootaxa. 2016 Jul 13;4137(4):585-91. doi: 10.11646/zootaxa.4137.4.11.


A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis.

Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; on behalf of the UK Cystic Fibrosis Gene Therapy Consortium.

Southampton (UK): NIHR Journals Library; 2016 Jul.


Predaceous water beetles (Coleoptera, Hydradephaga) of the Lake St Lucia system, South Africa: biodiversity, community ecology and conservation implications.

Perissinotto R, Bird MS, Bilton DT.

Zookeys. 2016 Jun 2;(595):85-135. doi: 10.3897/zookeys.595.8614. eCollection 2016.


Physiological niche and geographical range in European diving beetles (Coleoptera: Dytiscidae).

Cioffi R, Moody AJ, Millán A, Billington RA, Bilton DT.

Biol Lett. 2016 Jun;12(6). pii: 20160130. doi: 10.1098/rsbl.2016.0130.


A longitudinal study characterising a large adult primary ciliary dyskinesia population.

Shah A, Shoemark A, MacNeill SJ, Bhaludin B, Rogers A, Bilton D, Hansell DM, Wilson R, Loebinger MR.

Eur Respir J. 2016 Aug;48(2):441-50. doi: 10.1183/13993003.00209-2016. Epub 2016 Jun 10.


Corrigendum to "Risk of hemoptysis in cystic fibrosis clinical trials: A retrospective cohort study" [J Cyst Fibros (2015) 632-638].

Thompson V, Mayer-Hamblett N, Kloster M, Bilton D, Flume PA.

J Cyst Fibros. 2016 Sep;15(5):e54-e55. doi: 10.1016/j.jcf.2016.04.010. Epub 2016 May 17. No abstract available.

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