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Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities.

Cardin S, Bilodeau M, Roussy M, Aubert L, Milan T, Jouan L, Rouette A, Laramée L, Gendron P, Duchaine J, Decaluwe H, Spinella JF, Mourad S, Couture F, Sinnett D, Haddad É, Landry JR, Ma J, Humphries RK, Roux PP, Hébert J, Gruber TA, Wilhelm BT, Cellot S.

Blood Adv. 2019 Nov 12;3(21):3307-3321. doi: 10.1182/bloodadvances.2019030981.


Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.

Whalen KA, White BH, Quinn JM, Kriksciukaite K, Alargova R, Au Yeung TP, Bazinet P, Brockman A, DuPont MM, Oller H, Gifford J, Lemelin CA, Lim Soo P, Perino S, Moreau B, Sharma G, Shinde R, Sweryda-Krawiec B, Bilodeau MT, Wooster R.

Mol Cancer Ther. 2019 Nov;18(11):1926-1936. doi: 10.1158/1535-7163.MCT-19-0022.


Effects of intraoperative fluid balance during liver transplantation on postoperative acute kidney injury: an observational cohort study.

Carrier FM, Chassé M, Sylvestre MP, Girard M, Legendre-Courville L, Massicotte L, Bilodeau M.

Transplantation. 2019 Oct 21. doi: 10.1097/TP.0000000000002998. [Epub ahead of print]


Restrictive fluid management strategies and outcomes in liver transplantation: a systematic review.

Carrier FM, Chassé M, Wang HT, Aslanian P, Iorio S, Bilodeau M, Turgeon AF.

Can J Anaesth. 2019 Sep 25. doi: 10.1007/s12630-019-01480-y. [Epub ahead of print] Review.


Cryptic recurrent ACIN1-NUTM1 fusions in non-KMT2A-rearranged infant acute lymphoblastic leukemia.

Pincez T, Landry JR, Roussy M, Jouan L, Bilodeau M, Laramée L, Couture F, Sinnett D, Gendron P, Hébert J, Oligny L, Rouette A, Tran TH, Wilhelm BT, Bittencourt H, Cellot S.

Genes Chromosomes Cancer. 2020 Feb;59(2):125-130. doi: 10.1002/gcc.22808. Epub 2019 Oct 4.


IDH1 as a Cooperating Mutation in AML Arising in the Context of Shwachman-Diamond Syndrome.

Mourad S, Bilodeau M, Roussy M, Laramée L, Boulianne L, Rouette A, Jouan L, Gendron P, Duval M, Teira P, Hébert J, Bittencourt H, Pastore Y, Landry JR, Cellot S.

Front Oncol. 2019 Aug 14;9:772. doi: 10.3389/fonc.2019.00772. eCollection 2019.


Impact of Specialized Pediatric Palliative Care: A Systematic Review.

Marcus KL, Santos G, Ciapponi A, Comandé D, Bilodeau M, Wolfe J, Dussel V.

J Pain Symptom Manage. 2019 Aug 9. pii: S0885-3924(19)30449-X. doi: 10.1016/j.jpainsymman.2019.08.005. [Epub ahead of print] Review.


Centre of pressure displacements produced in sitting during virtual reality training in younger and older adults and patients who have had a stroke.

Sheehy L, Taillon-Hobson A, Finestone H, Bilodeau M, Yang C, Hafizi D, Sveistrup H.

Disabil Rehabil Assist Technol. 2019 Jun 20:1-9. doi: 10.1080/17483107.2019.1629118. [Epub ahead of print]


Experience of parents receiving results from a quality-of-life study in pediatric advanced cancer: A report from the PediQUEST study.

Bilodeau M, Dussel V, Wolfe J.

Pediatr Blood Cancer. 2019 Sep;66(9):e27880. doi: 10.1002/pbc.27880. Epub 2019 Jun 17.


Home-based virtual reality training after discharge from hospital-based stroke rehabilitation: a parallel randomized feasibility trial.

Sheehy L, Taillon-Hobson A, Sveistrup H, Bilodeau M, Yang C, Welch V, Hossain A, Finestone H.

Trials. 2019 Jun 7;20(1):333. doi: 10.1186/s13063-019-3438-9.


Impact of MELD Score-Based Organ Allocation on Mortality, Bleeding, and Transfusion in Liver Transplantation: A Before-and-After Observational Cohort Study.

Massicotte L, Carrier FM, Karakiewicz P, Hevesi Z, Thibeault L, Nozza A, Bilodeau M, Roy A, Denault AY.

J Cardiothorac Vasc Anesth. 2019 Oct;33(10):2719-2725. doi: 10.1053/j.jvca.2019.03.008. Epub 2019 Mar 8.


Older and young adults adopt different postural strategies during quiet bipedal stance after ankle plantarflexor fatigue.

Boyas S, Medd ER, Beaulieu S, Boileau A, Lajoie Y, Bilodeau M.

Neurosci Lett. 2019 May 14;701:208-212. doi: 10.1016/j.neulet.2019.02.044. Epub 2019 Feb 28.


Effect of Bilateral and Unilateral Plantarflexor Muscle Fatigue on Blind Navigation Precision and Gait Parameters.

Richer N, Bisson EJ, Bilodeau M, Paquet N, Lajoie Y.

J Mot Behav. 2020;52(1):41-49. doi: 10.1080/00222895.2019.1576157. Epub 2019 Feb 22.


Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.

White BH, Whalen K, Kriksciukaite K, Alargova R, Au Yeung T, Bazinet P, Brockman A, DuPont M, Oller H, Lemelin CA, Lim Soo P, Moreau B, Perino S, Quinn JM, Sharma G, Shinde R, Sweryda-Krawiec B, Wooster R, Bilodeau MT.

J Med Chem. 2019 Mar 14;62(5):2708-2719. doi: 10.1021/acs.jmedchem.8b02036. Epub 2019 Feb 28.


Oxaloacetate Protects Rat Liver From Experimental Warm Ischemia/Reperfusion Injury by Improving Cellular Energy Metabolism.

Merlen G, Raymond VA, Cassim S, Lapierre P, Bilodeau M.

Liver Transpl. 2019 Apr;25(4):627-639. doi: 10.1002/lt.25415. Epub 2019 Mar 1.


Effectiveness of interventions for non-specific low back pain in older adults. A systematic review and meta-analysis.

Nascimento PRCD, Costa LOP, Araujo AC, Poitras S, Bilodeau M.

Physiotherapy. 2019 Jun;105(2):147-162. doi: 10.1016/ Epub 2018 Nov 15.


Exclusion of Older Adults from Ongoing Clinical Trials on Low Back Pain: A Review of the WHO Trial Registry Database.

Carvalho do Nascimento PR, Ferreira ML, Poitras S, Bilodeau M.

J Am Geriatr Soc. 2019 Mar;67(3):603-608. doi: 10.1111/jgs.15684. Epub 2018 Dec 8. Review.


Effects of perioperative fluid management on postoperative outcomes in liver transplantation: a systematic review protocol.

Carrier FM, Chassé M, Wang HT, Aslanian P, Bilodeau M, Turgeon AF.

Syst Rev. 2018 Oct 31;7(1):180. doi: 10.1186/s13643-018-0841-3.


Type 3 cytokines IL-17A and IL-22 drive TGF-β-dependent liver fibrosis.

Fabre T, Molina MF, Soucy G, Goulet JP, Willems B, Villeneuve JP, Bilodeau M, Shoukry NH.

Sci Immunol. 2018 Oct 26;3(28). pii: eaar7754. doi: 10.1126/sciimmunol.aar7754.


The influence of knee extensor fatigue on lower extremity muscle activity during chair rise in young and older adults.

Bryanton MA, Bilodeau M.

Eur J Appl Physiol. 2019 Jan;119(1):61-71. doi: 10.1007/s00421-018-3999-4. Epub 2018 Oct 13.


Survival associated with cerebrospinal fluid analysis in downer adult dairy cows: A retrospective study (2006-2014).

Bilodeau MÈ, Achard D, Francoz D, Grimes C, Desrochers A, Nichols S, Babkine M, Fecteau G.

J Vet Intern Med. 2018 Sep;32(5):1780-1786. doi: 10.1111/jvim.15305. Epub 2018 Sep 14.


MK-7622: A First-in-Class M1 Positive Allosteric Modulator Development Candidate.

Beshore DC, N Di Marco C, Chang RK, Greshock TJ, Ma L, Wittmann M, Seager MA, Koeplinger KA, Thompson CD, Fuerst J, Hartman GD, Bilodeau MT, Ray WJ, Kuduk SD.

ACS Med Chem Lett. 2018 Apr 30;9(7):652-656. doi: 10.1021/acsmedchemlett.8b00095. eCollection 2018 Jul 12.


Metabolite profiling identifies a signature of tumorigenicity in hepatocellular carcinoma.

Cassim S, Raymond VA, Lacoste B, Lapierre P, Bilodeau M.

Oncotarget. 2018 Jun 1;9(42):26868-26883. doi: 10.18632/oncotarget.25525. eCollection 2018 Jun 1.


Upregulation of Krebs cycle and anaerobic glycolysis activity early after onset of liver ischemia.

Chan TS, Cassim S, Raymond VA, Gottschalk S, Merlen G, Zwingmann C, Lapierre P, Darby P, Mazer CD, Bilodeau M.

PLoS One. 2018 Jun 14;13(6):e0199177. doi: 10.1371/journal.pone.0199177. eCollection 2018.


The management of chronic hepatitis C: 2018 guideline update from the Canadian Association for the Study of the Liver.

Shah H, Bilodeau M, Burak KW, Cooper C, Klein M, Ramji A, Smyth D, Feld JJ; Canadian Association for the Study of the Liver.

CMAJ. 2018 Jun 4;190(22):E677-E687. doi: 10.1503/cmaj.170453. No abstract available.


Sofosbuvir-Based Therapy in the Pre-Liver Transplant Setting: The Canadian National Experience.

Al-Judaibi B, Thomas B, Wong P, Benmassaoud A, Chen JH, Dokus MK, Hussaini T, Bilodeau M, Burak KW, Marotta P, Yoshida EM.

Ann Hepatol. 2018 May-June;17(3):437-443. doi: 10.5604/01.3001.0011.7388. Epub 2018 Apr 9.


Metabolic reprogramming enables hepatocarcinoma cells to efficiently adapt and survive to a nutrient-restricted microenvironment.

Cassim S, Raymond VA, Dehbidi-Assadzadeh L, Lapierre P, Bilodeau M.

Cell Cycle. 2018;17(7):903-916. doi: 10.1080/15384101.2018.1460023. Epub 2018 May 21.


Impact of Sofosbuvir-Based Regimens for the Treatment of Hepatitis C After Liver Transplant on Renal Function: Results of a Canadian National Retrospective Study.

Faisal N, Bilodeau M, Aljudaibi B, Hirch G, Yoshida EM, Hussaini T, Ghali MP, Congly SE, Ma MM, Lilly LB.

Exp Clin Transplant. 2019 Feb;17(1):59-63. doi: 10.6002/ect.2017.0201. Epub 2018 Apr 4.


Successful Liver Transplants for Liver Failure Associated With Pyruvate Kinase Deficiency.

Chartier ME, Hart L, Paganelli M, Ahmed N, Bilodeau M, Alvarez F.

Pediatrics. 2018 Apr;141(Suppl 5):S385-S389. doi: 10.1542/peds.2016-3896.


How do we define and measure sarcopenia? Protocol for a systematic review.

Carvalho do Nascimento PR, Poitras S, Bilodeau M.

Syst Rev. 2018 Mar 27;7(1):51. doi: 10.1186/s13643-018-0712-y.


NUP98-BPTF gene fusion identified in primary refractory acute megakaryoblastic leukemia of infancy.

Roussy M, Bilodeau M, Jouan L, Tibout P, Laramée L, Lemyre E, Léveillé F, Tihy F, Cardin S, Sauvageau C, Couture F, Louis I, Choblet A, Patey N, Gendron P, Duval M, Teira P, Hébert J, Wilhelm BT, Choi JK, Gruber TA, Bittencourt H, Cellot S.

Genes Chromosomes Cancer. 2018 Jun;57(6):311-319. doi: 10.1002/gcc.22532. Epub 2018 Mar 28.


The Effect of Vision and Surface Compliance on Balance in Untrained and Strength Athletes.

Bryanton MA, Bilodeau M.

J Mot Behav. 2019;51(1):75-82. doi: 10.1080/00222895.2017.1423019. Epub 2018 Jan 29.


From in vivo to in vitro: Major metabolic alterations take place in hepatocytes during and following isolation.

Cassim S, Raymond VA, Lapierre P, Bilodeau M.

PLoS One. 2017 Dec 28;12(12):e0190366. doi: 10.1371/journal.pone.0190366. eCollection 2017.


Angiotensin 1-7 in the rostro-ventrolateral medulla increases blood pressure and splanchnic sympathetic nerve activity in anesthetized rats.

Bilodeau MS, Leiter JC.

Respir Physiol Neurobiol. 2018 Jan;247:103-111. doi: 10.1016/j.resp.2017.10.003. Epub 2017 Oct 6.


Household material hardship in families of children post-chemotherapy.

Bilodeau M, Ma C, Al-Sayegh H, Wolfe J, Bona K.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26743. Epub 2017 Sep 20.


A cobalt-nitrosyl complex with a hindered hydrotris(pyrazolyl)borate coligand: detailed electronic structure, and reactivity towards dioxygen.

Fujisawa K, Soma S, Kurihara H, Dong HT, Bilodeau M, Lehnert N.

Dalton Trans. 2017 Oct 10;46(39):13273-13289. doi: 10.1039/c7dt01565h.


Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.

Hart KM, Fabre T, Sciurba JC, Gieseck RL 3rd, Borthwick LA, Vannella KM, Acciani TH, de Queiroz Prado R, Thompson RW, White S, Soucy G, Bilodeau M, Ramalingam TR, Arron JR, Shoukry NH, Wynn TA.

Sci Transl Med. 2017 Jun 28;9(396). pii: eaal3694. doi: 10.1126/scitranslmed.aal3694.


Reply to: "Proposal of a novel MELD exception point system for hepatocellular carcinoma: Dynamics better than tumor characteristics?"

Bhat M, Ghali P, Bilodeau M.

J Hepatol. 2017 Jul;67(1):199-200. doi: 10.1016/j.jhep.2017.03.019. Epub 2017 Mar 24. No abstract available.


Dynamic postural control and associated attentional demands in contemporary dancers versus non-dancers.

Sirois-Leclerc G, Remaud A, Bilodeau M.

PLoS One. 2017 Mar 21;12(3):e0173795. doi: 10.1371/journal.pone.0173795. eCollection 2017.


Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity.

Scott JD, DeMong DE, Greshock TJ, Basu K, Dai X, Harris J, Hruza A, Li SW, Lin SI, Liu H, Macala MK, Hu Z, Mei H, Zhang H, Walsh P, Poirier M, Shi ZC, Xiao L, Agnihotri G, Baptista MA, Columbus J, Fell MJ, Hyde LA, Kuvelkar R, Lin Y, Mirescu C, Morrow JA, Yin Z, Zhang X, Zhou X, Chang RK, Embrey MW, Sanders JM, Tiscia HE, Drolet RE, Kern JT, Sur SM, Renger JJ, Bilodeau MT, Kennedy ME, Parker EM, Stamford AW, Nargund R, McCauley JA, Miller MW.

J Med Chem. 2017 Apr 13;60(7):2983-2992. doi: 10.1021/acs.jmedchem.7b00045. Epub 2017 Mar 16.


The role of thigh muscular efforts in limiting sit-to-stand capacity in healthy young and older adults.

Bryanton M, Bilodeau M.

Aging Clin Exp Res. 2017 Dec;29(6):1211-1219. doi: 10.1007/s40520-016-0702-7. Epub 2017 Feb 25.


Novel Immunotherapies for Autoimmune Hepatitis.

Cassim S, Bilodeau M, Vincent C, Lapierre P.

Front Pediatr. 2017 Jan 26;5:8. doi: 10.3389/fped.2017.00008. eCollection 2017. Review.


Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties.

Lacoste B, Raymond VA, Cassim S, Lapierre P, Bilodeau M.

PLoS One. 2017 Feb 2;12(2):e0171215. doi: 10.1371/journal.pone.0171215. eCollection 2017.


Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics.

Wolkenberg SE, Nolt MB, Bilodeau MT, Trotter BW, Manley PJ, Kett NR, Nanda KK, Wu Z, Cato MJ, Kane SA, Kiss L, Spencer RH, Wang J, Lynch JJ, Regan CP, Stump GL, Li B, White R, Yeh S, Dinsmore CJ, Lindsley CW, Hartman GD.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):1062-1069. doi: 10.1016/j.bmcl.2016.12.054. Epub 2017 Jan 16.


Structural characterization of nonactive site, TrkA-selective kinase inhibitors.

Su HP, Rickert K, Burlein C, Narayan K, Bukhtiyarova M, Hurzy DM, Stump CA, Zhang X, Reid J, Krasowska-Zoladek A, Tummala S, Shipman JM, Kornienko M, Lemaire PA, Krosky D, Heller A, Achab A, Chamberlin C, Saradjian P, Sauvagnat B, Yang X, Ziebell MR, Nickbarg E, Sanders JM, Bilodeau MT, Carroll SS, Lumb KJ, Soisson SM, Henze DA, Cooke AJ.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306. doi: 10.1073/pnas.1611577114. Epub 2016 Dec 30.


Protection against Acute Hepatocellular Injury Afforded by Liver Fibrosis Is Independent of T Lymphocytes.

Lacoste B, Raymond VA, Lapierre P, Bilodeau M.

PLoS One. 2016 Oct 28;11(10):e0165360. doi: 10.1371/journal.pone.0165360. eCollection 2016.


Guided wave scattering by geometrical change or damage: Application to characterization of fatigue crack and machined notch.

Quaegebeur N, Bouslama N, Bilodeau M, Guitel R, Masson P, Maslouhi A, Micheau P.

Ultrasonics. 2017 Jan;73:187-195. doi: 10.1016/j.ultras.2016.09.014. Epub 2016 Sep 14.


Proposal of a novel MELD exception point system for hepatocellular carcinoma based on tumor characteristics and dynamics.

Bhat M, Ghali P, Dupont B, Hilzenrat R, Tazari M, Roy A, Chaudhury P, Alvarez F, Carrier M, Bilodeau M.

J Hepatol. 2017 Feb;66(2):374-381. doi: 10.1016/j.jhep.2016.10.008. Epub 2016 Oct 15.


Postural stability with exhaustive repetitive sit-to-stand exercise in young adults.

Bryanton MA, Bilodeau M.

Hum Mov Sci. 2016 Oct;49:47-53. doi: 10.1016/j.humov.2016.06.006. Epub 2016 Jun 17.


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